Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

Science

Volumn 250, Issue 4985, 1990, Pages 1233-1238

  Malkin, David ^a   Li, Frederick P ^b,c   Strong, Louise C ^d   Fraumeni Jr , Joseph F ^b   Nelson, Camille E ^a,b,c   Kim, David H ^a   Kassel, Jayne ^a   Gryka, Magdalena A ^a   Bischoff, Farideh Z ^d   Tainsky, Michael A ^d   Friend, Stephen H ^a,e,f  

^a MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

^d UNIVERSITY OF TEXAS   (United States)

^e BOSTON CHILDREN S HOSPITAL   (United States)

^f HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BRAIN TUMOR; BREAST CANCER; CANCER; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FAMILIAL DISEASE; FEMALE; GENETICS; HUMAN; HUMAN CELL; MALE; MUTATION; PRIORITY JOURNAL; SARCOMA;

AMINO ACID SEQUENCE; BASE SEQUENCE; BREAST NEOPLASMS; CHROMOSOMES, HUMAN, PAIR 17; CLONING, MOLECULAR; CODON; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA; GENES, P53; GENETIC SCREENING; GERM CELLS; HUMAN; MOLECULAR SEQUENCE DATA; MUTATION; NEOPLASTIC SYNDROMES, HEREDITARY; PEDIGREE; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PROTEIN P53; REPETITIVE SEQUENCES, NUCLEIC ACID; SARCOMA; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0025633582     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1978757     Document Type: Article

References (0)