Smac mimetics as new cancer therapeutics

Anti-Cancer Drugs

Volumn 20, Issue 8, 2009, Pages 646-658

  Chen, Derrick J ^a   Huerta, Sergio ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Inhibitors of apoptosis; Smac direct IAP binding protein with low pI; Survivin; TRAIL; X linked inhibitor of apoptosis

Indexed keywords

CASPASE 3; CASPASE 9; CASPASE INHIBITOR; COMPOUND 3; COMPOUND A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN; LBW 242; LIPOFECTAMINE; PCDNA3.1 SMAC PROTEIN; POLYNUCLEOTIDE; PROTEIN BCL 2; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SM 164; SMAC MIMETIC AGENT; SMALL MOLECULE TRANSPORT AGENT; TUMOR NECROSIS FACTOR RECEPTOR 1; UNCLASSIFIED DRUG;

CANCER THERAPY; COLON CANCER; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; LUNG NON SMALL CELL CANCER; MELANOMA; OVARY CANCER; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REVIEW; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BIOMIMETIC MATERIALS; CELL SURVIVAL; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOCHONDRIAL PROTEINS; MOLECULAR STRUCTURE; NEOPLASMS;

EID: 70349329714     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/CAD.0b013e32832ced78     Document Type: Review

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