High pretreatment serum concentration of basic fibroblast growth factor is a predictor of poor prognosis in small cell lung cancer

Cancer Epidemiology Biomarkers and Prevention

Volumn 11, Issue 11, 2002, Pages 1492-1495

  Ruotsalainen, Tarja ^a   Joensuu, Heikki ^a   Mattson, Karin ^a   Salven, Petri ^b  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; CISPLATIN; EPIRUBICIN; ETOPOSIDE; FINNFERON ALPHA; IFOSFAMIDE; INTERFERON; RECOMBINANT ALPHA2A INTERFERON; ROCERON A;

ANGIOGENESIS; ARTICLE; CANCER STAGING; DISEASE ASSOCIATION; HUMAN; LUNG SMALL CELL CANCER; MAJOR CLINICAL STUDY; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; SURVIVAL;

ADULT; AGED; CARCINOMA, SMALL CELL; DISEASE PROGRESSION; FEMALE; FIBROBLAST GROWTH FACTOR 2; FINLAND; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM STAGING; PREDICTIVE VALUE OF TESTS; PROGNOSIS; SURVIVAL ANALYSIS; TIME FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 0036847635     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Folkman, J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med., 1: 27-31, 1995
2. Hanahan, D., and Folkman, J, Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell, 86: 353-364, 1996
3. Friesel, R. E., and Maciag. T. Molecular mechanisms of angiogenesis: Fibroblast growth factor signal transduction. FASEB J., 9: 919-925, 1995
4. Bikfalvi, A., Klein, S., Pintucci, G., and Rifkin, D. B. Biological roles of fibroblast growth factor-2. Endocr. Rev., 18: 26-45, 1997
5. Hori, A., Sasada, R., Matsutani. E., Naito, K., Sakura, Y., Fujita, T., and Kozai, Y. Suppression of solid tumor growth by immunoneutralizing monoclonal antibody against human basic fibroblast growth factor. Cancer Res, 51: 6180-6184, 1991
6. Dirix, L. Y., Vermeulen, P. B. Pawinski, A., Prove, A., Benoy, I., De Pooter, C., Martin, M., and Van Oosterom, A. T. Elevated levels of the angiogenic cytokines basic fibroblast growth factor and vascular endothelial growth factor in sera of cancer patients. Br. J. Cancer, 76: 238 -243, 1997
7. Cronauer, M. V., Hittmair, A., Eder, I. E., Hobisch, A., Culig, Z., Ramoner, R., Zhang, J., Bartsch, G., Reissigl, A., Radmayr, C., Thurnher, M., and Klocker, H. Basic fibroblast growth factor levels in cancer cells and in sera of patients suffering from proliferative disorders of the prostate. Prostate, 31: 223-233, 1997
8. Landriscina, M., Cassano, A., Ratto, C., Longo, R., Ippoliti, M., Palazzotti, B., Crucitti, F., and Barone, C. Quantitative analysis of basic fibroblast growth factor and vascular endothelial growth factor in human colorectal cancer. Br. J. Cancer, 78: 765-770, 1998
9. Chodak, G. W., Hospelhorn, V., Judge, S. M., Mayforth, R., Koeppen, H., and Sasse, J. Increased levels of fibroblast growth factor-like activity in urine from patients with bladder or kidney cancer. Cancer Res., 48: 2083-2088, 1988
10. Nguyen, M., Watanabe, H., Budson, A. E., Richie, J. P., Hayes, D. F., and Folkman, J. Elevated levels of an angiogenic peptide, basic fibroblast growth factor, in the urine of patients with a wide spectrum of cancers. J. Natl. Cancer Inst. (Bethesda), 86: 356-361, 1994
11. O'Brien, T. S., Smith, K., Cranston, D., Fuggle, S., Bicknell, R., and Harris, A. L. Urinary basic fibroblast growth factor in patients with bladder cancer and benign prostatic hypertrophy. Br. J. Urol., 76: 311-314, 1995
12. Ugurel, S., Rappl, G., Tilgen, W., and Reinhold, U. Increased serum concentration of angiogenic factors in malignant melanoma patients correlates with tumor progression and survival. J. Clin. Oncol., 19: 577-583, 2001
13. Leunig, A., Tauber, S., Spaett, R., Grevers, G., and Leunig, M. Basic fibroblast growth factor in serum and urine of patients with head and neck cancer. Oncol. Rep., 5: 955-958, 1998
14. Dirix, L. Y., Vermeulen, P. B., Hubens, G., Benoy, I., Martin, M., De Pooter, C., and Van Oosterom, A., T. Serum basic fibroblast growth factor and vascular endothelial growth factor and tumour growth kinetics in advanced colorectal cancer. Ann. Oncol., 7: 843-848, 1996
15. Menzel, T., Rahman, Z., Calleja, E., White, K., Wilson, E. L., Wieder, R., and Gabrilove, J. Elevated intracellular level of basic fibroblast growth factor correlates with stage of chronic lymphocytic leukemia and is associated with resistance to fludarabine. Blood, 87: 1056-1063, 1996
16. Salven, P., Teerenhovi, L., and Joensuu, H. A high pretreatment serum basic fibroblast growth factor concentration is an independent predictor of poor prognosis in non-Hodgkin's lymphoma. Blood, 94: 3334-3339, 1999
17. Salven, P., Orpana, A., Teerenhovi, L., and Joensuu, H. Simultaneous elevation in the serum concentrations of the angiogenic growth factors VEGF and bFGF is an independent predictor of poor prognosis in non-Hodgkin lymphoma: A single- institution study of 200 patients. Blood, 96: 3712-3718, 2000
18. Mattson. K., Niiranen, A., Pyrhönen, S., Riska, H., Maasilta, P., Halme, M., Jekunen, A., Sarna, S., and Cantell. K. Concomitant chemotherapy (CT) and interferon α (IFNα) for SCLC. Proc. Am. Soc. Clin. Oncol., 14: 370, 1995
19. Song, S., Wientjes, M. G., Gan, Y., and Au, J. L. Fibroblast growth factors: An epigenetic mechanism of broad spectrum resistance to anticancer drugs. Proc. Natl. Acad. Sci. USA, 97: 8658-8663, 2000
20. Brunner, G., Nguyen, H., Gabrilove, J., Rifkin, D., B., and Wilson, E. L. Basic fibroblast growth factor expression in human bone marrow and peripheral blood cells. Blood, 81: 631-638, 1993
21. Gu, X. F., Bikfalvi, A., Chen, Y. Z., Caen, J. P., and Han, Z., C. Constitutive and selective expression of basic fibroblast growth factor in human leukaemia cell lines. Eur. J. Haematol., 55: 189-194, 1995
22. Peoples, G. E., Blotnick, S., Takahashi, K., Freeman, M. R., Klagsbrun, M., and Eberlein, T. J. T lymphocytes that infiltrate tumors and atherosclerotic plaques produce heparin-binding epidermal growth factor-like growth factor and basic fibroblast growth factor: A potential pathologic role. Proc. Natl. Acad. Sci. USA, 92: 6547-6551, 1995
23. Blotnick, S., Peoples, G. E., Freeman, M. R., Eberlein, T. J., and Klagsbrun, M. T lymphocytes synthesize and export heparin-binding epidermal growth factor-like growth factor and basic fibroblast growth factor, mitogens for vascular cells and fibroblasts: Differential production and release by CD4+ and CD8+ T cells. Proc. Natl. Acad. Sci. USA, 91: 2890-2894, 1994
24. Kuwabara, K., Ogawa, S., Matsumoto, M., Koga, S., Clauss, M., Pinsky, D. J., Lyn, P., Leavy, J., Witte, L., Joseph-Silverstein, J., et al. Hypoxia-mediated induction of acidic/basic fibroblast growth factor and platelet-derived growth factor in mononuclear phagocytes stimulates growth of hypoxic endothelial cells. Proc. Natl. Acad. Sci. USA, 92: 4606-4610, 1995
25. Kandel, J., Bossy-Wetzel, E., Radvanyi, F., Klagsbrun, M., Folkman, J., and Hanahan, D. Neovascularization is associated with a switch to the export of bFGF in the multistep development of fibrosarcoma. Cell, 66: 1095-1104, 1991
26. Soutter, A. D., Nguyen, M., Watanabe, H., and Folkman, J. Basic fibroblast growth factor secreted by an animal tumor is detectable in urine. Cancer Res., 53: 5297-5299, 1993
27. Hondermarck, H., Courty, J., Boilly, B., and Thomas, D. Distribution of intravenously administered acidic and basic fibroblast growth factors in the mouse. Experientia (Basel), 46: 973-974, 1990