SMAC/Diablo mediates the proapoptotic function of PUMA by regulating PUMA-induced mitochondrial events

Oncogene

Volumn 26, Issue 29, 2007, Pages 4189-4198

  Yu, J ^a   Wang, P ^a   Ming, L ^a   Wood, M A ^a   Zhang, L ^a  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

Apoptosis; DNA damage; Mitochondria; PUMA; SMAC Diablo

Indexed keywords

ANTINEOPLASTIC AGENT; BH3 PROTEIN; CASPASE 3; CASPASE 9; CYTOCHROME C; DOXORUBICIN; ETOPOSIDE; N ACETYLLEUCYLLEUCYLNORLEUCINAL; P53 UPREGULATED MODULATOR OF APOPTOSIS; PROTEIN BCL 2; PUROMYCIN; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER CHEMOTHERAPY; CELL CYCLE; CELL STRAIN HCT116; COLON CANCER; CONTROLLED STUDY; CYTOSOL; DNA DAMAGE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; ONCOGENE MYC; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RNA INTERFERENCE; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASE 9; CELL LINE, TUMOR; CYTOCHROMES C; HCT116 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; PROTO-ONCOGENE PROTEINS;

INTRACISTERNAL A-PARTICLES;

EID: 34250880206     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210196     Document Type: Article

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