Role of Reactive Oxygen Species-elicited Apoptosis in the Pathophysiology of Mitochondrial and Neurodegenerative Diseases Associated With Mitochondrial DNA Mutations

Journal of the Formosan Medical Association

Volumn 108, Issue 8, 2009, Pages 599-611

  Liu, Chun Yi ^a   Lee, Cheng Feng ^a   Wei, Yau Huei ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

apoptosis; mitochondrial diseases; mitochondrial DNA mutation; neurodegenerative diseases; reactive oxygen species

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 4 HYDROXYNONENAL; ACETYLCYSTEINE; ALPHA SYNUCLEIN; AMYLOID BETA PROTEIN; ANTIOXIDANT; APOPTOSIS INDUCING FACTOR; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 8; CYCLOPHILIN D; CYTOCHROME C; CYTOCHROME C OXIDASE; DEOXYRIBONUCLEASE I; DJ 1 PROTEIN; GLUTATHIONE; LEUCINE RICH REPEAT KINASE 2; MALONALDEHYDE; MANGANESE SUPEROXIDE DISMUTASE; MELATONIN; MITOCHONDRIAL DNA; PARKIN; PROCASPASE 3; PROCASPASE 9; PROTEIN BAX; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; STAUROSPORINE; UBIDECARENONE;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL MODEL; APOPTOSIS; CELL DAMAGE; CELL FUNCTION; CHRONIC PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CYBRID; DEGENERATIVE DISEASE; DISEASE PREDISPOSITION; DRUG MECHANISM; DRUG SAFETY; DRUG TOLERABILITY; GENE DELETION; GENE MUTATION; HUMAN; KEARNS SAYRE SYNDROME; LEBER HEREDITARY OPTIC NEUROPATHY; LEIGH DISEASE; LIPID PEROXIDATION; MALE INFERTILITY; MELAS SYNDROME; MERRF SYNDROME; MITOCHONDRIAL DNA DISORDER; MITOCHONDRION; NARP SYNDROME; NEUROPROTECTION; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PATHOPHYSIOLOGY; PEARSON SYNDROME; POINT MUTATION; RANDOMIZED CONTROLLED TRIAL; REVIEW; ULTRAVIOLET RADIATION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; DISEASE MODELS, ANIMAL; DNA, MITOCHONDRIAL; HUMANS; MITOCHONDRIA; MITOCHONDRIAL DISEASES; MUTATION; NEURODEGENERATIVE DISEASES; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 70349289808     PISSN: None     EISSN: 09296646     Source Type: Journal    
DOI: 10.1016/S0929-6646(09)60380-6     Document Type: Review

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