-
1
-
-
21344445937
-
Molecular neurology of prion disease
-
Collinge J. Molecular neurology of prion disease. J. Neurol. Neurosurg. Psychiatr. 76 (2005) 906-919
-
(2005)
J. Neurol. Neurosurg. Psychiatr.
, vol.76
, pp. 906-919
-
-
Collinge, J.1
-
2
-
-
0842281643
-
Mammalian prion biology: one century of evolving concepts
-
Aguzzi A., and Polymenidou M. Mammalian prion biology: one century of evolving concepts. Cell 116 (2004) 313-327
-
(2004)
Cell
, vol.116
, pp. 313-327
-
-
Aguzzi, A.1
Polymenidou, M.2
-
3
-
-
33646000833
-
Prions and their lethal journey to the brain
-
Mabbott N.A., and MacPherson G.G. Prions and their lethal journey to the brain. Nat. Rev. Microbiol. 4 (2006) 201-211
-
(2006)
Nat. Rev. Microbiol.
, vol.4
, pp. 201-211
-
-
Mabbott, N.A.1
MacPherson, G.G.2
-
4
-
-
78651041685
-
Degenerative disease of the central nervous system in New Guinea - the endemic occurrence of 'kuru'in the native population
-
Gajdusek D.C., and Zigas V. Degenerative disease of the central nervous system in New Guinea - the endemic occurrence of 'kuru'in the native population. New Engl. J. Med. 257 (1957) 974-978
-
(1957)
New Engl. J. Med.
, vol.257
, pp. 974-978
-
-
Gajdusek, D.C.1
Zigas, V.2
-
5
-
-
0029999065
-
A new variant of prion disease
-
Collinge J., and Rossor M. A new variant of prion disease. Lancet 347 (1996) 916-917
-
(1996)
Lancet
, vol.347
, pp. 916-917
-
-
Collinge, J.1
Rossor, M.2
-
6
-
-
0342951746
-
A new variant of Creutzfeldt-Jakob disease in the UK
-
Will R.G., et al. A new variant of Creutzfeldt-Jakob disease in the UK. Lancet 347 (1996) 921-925
-
(1996)
Lancet
, vol.347
, pp. 921-925
-
-
Will, R.G.1
-
7
-
-
1142273431
-
Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion
-
Llewelyn C.A., Hewitt P.E., Knight R.S., Amar K., Cousens S., Mackenzie J., and Will R.G. Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion. Lancet 363 (2004) 417-421
-
(2004)
Lancet
, vol.363
, pp. 417-421
-
-
Llewelyn, C.A.1
Hewitt, P.E.2
Knight, R.S.3
Amar, K.4
Cousens, S.5
Mackenzie, J.6
Will, R.G.7
-
8
-
-
33744511127
-
Prion infections, blood and transfusions
-
Aguzzi A., and Glatzel M. Prion infections, blood and transfusions. Nat. Clin. Pract. Neurol. 2 (2006) 321-329
-
(2006)
Nat. Clin. Pract. Neurol.
, vol.2
, pp. 321-329
-
-
Aguzzi, A.1
Glatzel, M.2
-
9
-
-
0033616564
-
Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication
-
Raeber A.J., et al. Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication. Proc. Natl. Acad. Sci. USA 96 (1999) 3987-3992
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 3987-3992
-
-
Raeber, A.J.1
-
10
-
-
0033577717
-
PrP-dependent association of prions with splenic but not circulating lymphocytes of scrapie-infected mice
-
Raeber A.J., Klein M.A., Frigg R., Flechsig E., Aguzzi A., and Weissmann C. PrP-dependent association of prions with splenic but not circulating lymphocytes of scrapie-infected mice. EMBO J. 18 (1999) 2702-2706
-
(1999)
EMBO J.
, vol.18
, pp. 2702-2706
-
-
Raeber, A.J.1
Klein, M.A.2
Frigg, R.3
Flechsig, E.4
Aguzzi, A.5
Weissmann, C.6
-
11
-
-
34547632554
-
Prion biology: the quest for the test
-
Aguzzi A. Prion biology: the quest for the test. Nat. Meth. 4 (2007) 614-616
-
(2007)
Nat. Meth.
, vol.4
, pp. 614-616
-
-
Aguzzi, A.1
-
12
-
-
33745440706
-
Kuru in the 21st century - an acquired human prion disease with very long incubation periods
-
Collinge J., Whitfield J., McKintosh E., Beck J., Mead S., Thomas D.J., and Alpers M.P. Kuru in the 21st century - an acquired human prion disease with very long incubation periods. Lancet 367 (2006) 2068-2074
-
(2006)
Lancet
, vol.367
, pp. 2068-2074
-
-
Collinge, J.1
Whitfield, J.2
McKintosh, E.3
Beck, J.4
Mead, S.5
Thomas, D.J.6
Alpers, M.P.7
-
13
-
-
34347323652
-
Identification and characterization of two bovine spongiform encephalopathy cases diagnosed in the United States
-
Richt J.A., et al. Identification and characterization of two bovine spongiform encephalopathy cases diagnosed in the United States. J. Vet. Diagn. Invest. 19 (2007) 142-154
-
(2007)
J. Vet. Diagn. Invest.
, vol.19
, pp. 142-154
-
-
Richt, J.A.1
-
14
-
-
1542357669
-
Identification of a second bovine amyloidotic spongiform encephalopathy: molecular similarities with sporadic Creutzfeldt-Jakob disease
-
Casalone C., Zanusso G., Acutis P., Ferrari S., Capucci L., Tagliavini F., Monaco S., and Caramelli M. Identification of a second bovine amyloidotic spongiform encephalopathy: molecular similarities with sporadic Creutzfeldt-Jakob disease. Proc. Natl. Acad. Sci. USA 101 (2004) 3065-3070
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3065-3070
-
-
Casalone, C.1
Zanusso, G.2
Acutis, P.3
Ferrari, S.4
Capucci, L.5
Tagliavini, F.6
Monaco, S.7
Caramelli, M.8
-
15
-
-
0037072088
-
Incidence of Creutzfeldt-Jakob disease in Switzerland
-
Glatzel M., Rogivue C., Ghani A., Streffer J.R., Amsler L., and Aguzzi A. Incidence of Creutzfeldt-Jakob disease in Switzerland. Lancet 360 (2002) 139-1341
-
(2002)
Lancet
, vol.360
, pp. 139-1341
-
-
Glatzel, M.1
Rogivue, C.2
Ghani, A.3
Streffer, J.R.4
Amsler, L.5
Aguzzi, A.6
-
16
-
-
50049084898
-
A prion disease of cervids: chronic wasting disease
-
Sigurdson C.J. A prion disease of cervids: chronic wasting disease. Vet. Res. 39 (2008) 41
-
(2008)
Vet. Res.
, vol.39
, pp. 41
-
-
Sigurdson, C.J.1
-
17
-
-
13844275788
-
Prions, cytokines, and chemokines: a meeting in lymphoid organs
-
Aguzzi A., and Heikenwalder M. Prions, cytokines, and chemokines: a meeting in lymphoid organs. Immunity 22 (2005) 145-154
-
(2005)
Immunity
, vol.22
, pp. 145-154
-
-
Aguzzi, A.1
Heikenwalder, M.2
-
18
-
-
0035928432
-
Tissue distribution of protease resistant prion protein in variant CJD using a highly sensitive immuno-blotting assay
-
Wadsworth J.D.F., Joiner S., Hill A.F., Campbell T.A., Desbruslais M., Luthert P.J., and Collinge J. Tissue distribution of protease resistant prion protein in variant CJD using a highly sensitive immuno-blotting assay. Lancet 358 (2001) 171-180
-
(2001)
Lancet
, vol.358
, pp. 171-180
-
-
Wadsworth, J.D.F.1
Joiner, S.2
Hill, A.F.3
Campbell, T.A.4
Desbruslais, M.5
Luthert, P.J.6
Collinge, J.7
-
19
-
-
0242361687
-
Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob disease
-
Glatzel M., Abela E., Maissen M., and Aguzzi A. Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob disease. New Engl. J. Med. 349 (2003) 1812-1820
-
(2003)
New Engl. J. Med.
, vol.349
, pp. 1812-1820
-
-
Glatzel, M.1
Abela, E.2
Maissen, M.3
Aguzzi, A.4
-
20
-
-
33644651130
-
Detection and localization of PrPSc in the skeletal muscle of patients with variant, iatrogenic, and sporadic forms of Creutzfeldt-Jakob disease
-
Peden A.H., Ritchie D.L., Head M.W., and Ironside J.W. Detection and localization of PrPSc in the skeletal muscle of patients with variant, iatrogenic, and sporadic forms of Creutzfeldt-Jakob disease. Am. J. Pathol. 168 (2006) 927-935
-
(2006)
Am. J. Pathol.
, vol.168
, pp. 927-935
-
-
Peden, A.H.1
Ritchie, D.L.2
Head, M.W.3
Ironside, J.W.4
-
21
-
-
0842347567
-
Prion deposition in olfactory biopsy of sporadic Creutzfeldt-Jakob disease
-
Tabaton M., Monaco S., Cordone M.P., Colucci M., Giaccone G., Tagliavini F., and Zanusso G. Prion deposition in olfactory biopsy of sporadic Creutzfeldt-Jakob disease. Ann. Neurol. 55 (2004) 294-296
-
(2004)
Ann. Neurol.
, vol.55
, pp. 294-296
-
-
Tabaton, M.1
Monaco, S.2
Cordone, M.P.3
Colucci, M.4
Giaccone, G.5
Tagliavini, F.6
Zanusso, G.7
-
22
-
-
33749618609
-
Infectious prions in the saliva and blood of deer with chronic wasting disease
-
Mathiason C.K., et al. Infectious prions in the saliva and blood of deer with chronic wasting disease. Science 314 (2006) 133-136
-
(2006)
Science
, vol.314
, pp. 133-136
-
-
Mathiason, C.K.1
-
23
-
-
33644554856
-
Prions in skeletal muscles of deer with chronic wasting disease
-
Angers R.C., Browning S.R., Seward T.S., Sigurdson C.J., Miller M.W., Hoover E.A., and Telling G.C. Prions in skeletal muscles of deer with chronic wasting disease. Science 311 (2006) 1117
-
(2006)
Science
, vol.311
, pp. 1117
-
-
Angers, R.C.1
Browning, S.R.2
Seward, T.S.3
Sigurdson, C.J.4
Miller, M.W.5
Hoover, E.A.6
Telling, G.C.7
-
24
-
-
0347949706
-
Creutzfeldt-Jakob disease and inclusion body myositis: Alig
-
Kovacs G.G., et al. Creutzfeldt-Jakob disease and inclusion body myositis: Alig. Ann. Neurol. 55 (2004) 121-125
-
(2004)
Ann. Neurol.
, vol.55
, pp. 121-125
-
-
Kovacs, G.G.1
-
25
-
-
58149234376
-
Prions in milk from ewes incubating natural scrapie
-
Lacroux C., et al. Prions in milk from ewes incubating natural scrapie. PLoS Pathog. 4 (2008) e1000238
-
(2008)
PLoS Pathog.
, vol.4
-
-
Lacroux, C.1
-
26
-
-
30744466152
-
PrPSc in mammary glands of sheep affected by scrapie and mastitis
-
Ligios C., et al. PrPSc in mammary glands of sheep affected by scrapie and mastitis. Nat. Med. 11 (2005) 1137-1138
-
(2005)
Nat. Med.
, vol.11
, pp. 1137-1138
-
-
Ligios, C.1
-
27
-
-
13844259181
-
Chronic lymphocytic inflammation specifies the organ tropism of prions
-
Heikenwalder M., et al. Chronic lymphocytic inflammation specifies the organ tropism of prions. Science 307 (2005) 1107-1110
-
(2005)
Science
, vol.307
, pp. 1107-1110
-
-
Heikenwalder, M.1
-
28
-
-
33646455867
-
Abnormal prion protein in ectopic lymphoid tissue in a kidney of an asymptomatic white-tailed deer experimentally inoculated with the agent of chronic wasting disease
-
Hamir A.N., Kunkle R.A., Miller J.M., and Hall S.M. Abnormal prion protein in ectopic lymphoid tissue in a kidney of an asymptomatic white-tailed deer experimentally inoculated with the agent of chronic wasting disease. Vet. Pathol. 43 (2006) 367-369
-
(2006)
Vet. Pathol.
, vol.43
, pp. 367-369
-
-
Hamir, A.N.1
Kunkle, R.A.2
Miller, J.M.3
Hall, S.M.4
-
29
-
-
26844563437
-
Coincident scrapie infection and nephritis lead to urinary prion excretion
-
Seeger H., et al. Coincident scrapie infection and nephritis lead to urinary prion excretion. Science 310 (2005) 324-326
-
(2005)
Science
, vol.310
, pp. 324-326
-
-
Seeger, H.1
-
30
-
-
58849129829
-
Bacterial colitis increases susceptibility to oral prion disease
-
Sigurdson C.J., et al. Bacterial colitis increases susceptibility to oral prion disease. J. Infect. Dis. 199 (2009) 243-252
-
(2009)
J. Infect. Dis.
, vol.199
, pp. 243-252
-
-
Sigurdson, C.J.1
-
31
-
-
33748857338
-
Pathogenesis of prion diseases: current status and future outlook
-
Aguzzi A., and Heikenwalder M. Pathogenesis of prion diseases: current status and future outlook. Nat. Rev. Microbiol. 4 (2006) 765-775
-
(2006)
Nat. Rev. Microbiol.
, vol.4
, pp. 765-775
-
-
Aguzzi, A.1
Heikenwalder, M.2
-
32
-
-
33748440083
-
Urine from scrapie-infected hamsters comprises low levels of prion infectivity
-
Kariv-Inbal Z., Ben-Hur T., Grigoriadis N.C., Engelstein R., and Gabizon R. Urine from scrapie-infected hamsters comprises low levels of prion infectivity. Neurodegener. Dis. 3 (2006) 123-128
-
(2006)
Neurodegener. Dis.
, vol.3
, pp. 123-128
-
-
Kariv-Inbal, Z.1
Ben-Hur, T.2
Grigoriadis, N.C.3
Engelstein, R.4
Gabizon, R.5
-
33
-
-
33749020837
-
Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host
-
Meyer-Luehmann M., et al. Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host. Science 313 (2006) 1781-1784
-
(2006)
Science
, vol.313
, pp. 1781-1784
-
-
Meyer-Luehmann, M.1
-
34
-
-
0242300624
-
Games played by rogue proteins in prion disorders and Alzheimer's disease
-
Aguzzi A., and Haass C. Games played by rogue proteins in prion disorders and Alzheimer's disease. Science 302 (2003) 814-818
-
(2003)
Science
, vol.302
, pp. 814-818
-
-
Aguzzi, A.1
Haass, C.2
-
35
-
-
33751352055
-
Cell biology: infectious Alzheimer's disease?
-
Riek R. Cell biology: infectious Alzheimer's disease?. Nature 444 (2006) 429-431
-
(2006)
Nature
, vol.444
, pp. 429-431
-
-
Riek, R.1
-
36
-
-
0020321767
-
Novel proteinaceous infectious particles cause scrapie
-
Prusiner S.B. Novel proteinaceous infectious particles cause scrapie. Science 216 (1982) 136-144
-
(1982)
Science
, vol.216
, pp. 136-144
-
-
Prusiner, S.B.1
-
37
-
-
0027534612
-
Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing
-
Stahl N., Baldwin M.A., Teplow D.B., Hood L., Gibson B.W., Burlingame A.L., and Prusiner S.B. Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing. Biochemistry 32 (1993) 1991-2002
-
(1993)
Biochemistry
, vol.32
, pp. 1991-2002
-
-
Stahl, N.1
Baldwin, M.A.2
Teplow, D.B.3
Hood, L.4
Gibson, B.W.5
Burlingame, A.L.6
Prusiner, S.B.7
-
38
-
-
0029937271
-
NMR structure of the mouse prion protein domain PrP(121-231)
-
Riek R., Hornemann S., Wider G., Billeter M., Glockshuber R., and Wüthrich K. NMR structure of the mouse prion protein domain PrP(121-231). Nature 382 (1996) 180-182
-
(1996)
Nature
, vol.382
, pp. 180-182
-
-
Riek, R.1
Hornemann, S.2
Wider, G.3
Billeter, M.4
Glockshuber, R.5
Wüthrich, K.6
-
39
-
-
0027332116
-
Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins
-
Pan K.M., et al. Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins. Proc. Natl. Acad. Sci. USA 90 (1993) 10962-10966
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10962-10966
-
-
Pan, K.M.1
-
40
-
-
0027182522
-
Conformational transitions, dissociation, and unfolding of scrapie amyloid (prion) protein
-
Safar J., Roller P.P., Gajdusek D.C., and Gibbs Jr. C.J. Conformational transitions, dissociation, and unfolding of scrapie amyloid (prion) protein. J. Biol. Chem. 268 (1993) 20276-20284
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 20276-20284
-
-
Safar, J.1
Roller, P.P.2
Gajdusek, D.C.3
Gibbs Jr., C.J.4
-
41
-
-
36049020231
-
A general model of prion strains and their pathogenicity
-
Collinge J., and Clarke A.R. A general model of prion strains and their pathogenicity. Science 318 (2007) 930-936
-
(2007)
Science
, vol.318
, pp. 930-936
-
-
Collinge, J.1
Clarke, A.R.2
-
43
-
-
24644486403
-
Extraneural prion neuroinvasion without lymphoreticular system infection
-
Bartz J.C., Dejoia C., Tucker T., Kincaid A.E., and Bessen R.A. Extraneural prion neuroinvasion without lymphoreticular system infection. J. Virol. 79 (2005) 11858-11863
-
(2005)
J. Virol.
, vol.79
, pp. 11858-11863
-
-
Bartz, J.C.1
Dejoia, C.2
Tucker, T.3
Kincaid, A.E.4
Bessen, R.A.5
-
44
-
-
2342522638
-
Understanding the diversity of prions
-
Aguzzi A. Understanding the diversity of prions. Nat. Cell Biol. 6 (2004) 290-292
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 290-292
-
-
Aguzzi, A.1
-
45
-
-
0020080097
-
Measurement of the scrapie agent using an incubation time interval assay
-
Prusiner S.B., Cochran S.P., Groth D.F., Downey D.E., Bowman K.A., and Martinez H.M. Measurement of the scrapie agent using an incubation time interval assay. Ann. Neurol. 11 (1982) 353-358
-
(1982)
Ann. Neurol.
, vol.11
, pp. 353-358
-
-
Prusiner, S.B.1
Cochran, S.P.2
Groth, D.F.3
Downey, D.E.4
Bowman, K.A.5
Martinez, H.M.6
-
46
-
-
0141593548
-
A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions
-
Klohn P.C., Stoltze L., Flechsig E., Enari M., and Weissmann C. A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions. Proc. Natl. Acad. Sci. USA 100 (2003) 11666-11671
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 11666-11671
-
-
Klohn, P.C.1
Stoltze, L.2
Flechsig, E.3
Enari, M.4
Weissmann, C.5
-
47
-
-
0021023167
-
A protease-resistant protein is a structural component of the scrapie prion
-
McKinley M.P., Bolton D.C., and Prusiner S.B. A protease-resistant protein is a structural component of the scrapie prion. Cell 35 (1983) 57-62
-
(1983)
Cell
, vol.35
, pp. 57-62
-
-
McKinley, M.P.1
Bolton, D.C.2
Prusiner, S.B.3
-
49
-
-
0026644090
-
Regional mapping of prion proteins in brain
-
Taraboulos A., Jendroska K., Serban D., Yang S.L., DeArmond S.J., and Prusiner S.B. Regional mapping of prion proteins in brain. Proc. Natl. Acad. Sci. USA 89 (1992) 7620-7624
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7620-7624
-
-
Taraboulos, A.1
Jendroska, K.2
Serban, D.3
Yang, S.L.4
DeArmond, S.J.5
Prusiner, S.B.6
-
50
-
-
0035859102
-
Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding
-
Saborio G.P., Permanne B., and Soto C. Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding. Nature 411 (2001) 810-813
-
(2001)
Nature
, vol.411
, pp. 810-813
-
-
Saborio, G.P.1
Permanne, B.2
Soto, C.3
-
51
-
-
24744446203
-
Detection of prions in blood
-
Castilla J., Saa P., and Soto C. Detection of prions in blood. Nat. Med. 11 (2005) 982-985
-
(2005)
Nat. Med.
, vol.11
, pp. 982-985
-
-
Castilla, J.1
Saa, P.2
Soto, C.3
-
53
-
-
0031720905
-
Sc molecules with different conformations
-
Sc molecules with different conformations. Nat. Med. 4 (1998) 1157-1165
-
(1998)
Nat. Med.
, vol.4
, pp. 1157-1165
-
-
Safar, J.1
Wille, H.2
Itri, V.3
Groth, D.4
Serban, H.5
Torchia, M.6
Cohen, F.7
Prusiner, S.8
-
54
-
-
0026600865
-
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
-
Büeler H.R., et al. Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature 356 (1992) 577-582
-
(1992)
Nature
, vol.356
, pp. 577-582
-
-
Büeler, H.R.1
-
55
-
-
0242363656
-
Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis
-
Mallucci G., Dickinson A., Linehan J., Klohn P.C., Brandner S., and Collinge J. Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis. Science 302 (2003) 871-874
-
(2003)
Science
, vol.302
, pp. 871-874
-
-
Mallucci, G.1
Dickinson, A.2
Linehan, J.3
Klohn, P.C.4
Brandner, S.5
Collinge, J.6
-
56
-
-
42049099020
-
Physiology of the prion protein
-
Linden R., Martins V.R., Prado M.A., Cammarota M., Izquierdo I., and Brentani R.R. Physiology of the prion protein. Physiol. Rev. 88 (2008) 673-728
-
(2008)
Physiol. Rev.
, vol.88
, pp. 673-728
-
-
Linden, R.1
Martins, V.R.2
Prado, M.A.3
Cammarota, M.4
Izquierdo, I.5
Brentani, R.R.6
-
57
-
-
0029825830
-
Normal host prion protein (PrPC) is required for scrapie spread within the central nervous system
-
Brandner S., Raeber A., Sailer A., Blattler T., Fischer M., Weissmann C., and Aguzzi A. Normal host prion protein (PrPC) is required for scrapie spread within the central nervous system. Proc. Natl. Acad. Sci. USA 93 (1996) 13148-13151
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 13148-13151
-
-
Brandner, S.1
Raeber, A.2
Sailer, A.3
Blattler, T.4
Fischer, M.5
Weissmann, C.6
Aguzzi, A.7
-
58
-
-
20344394154
-
Anchorless prion protein results in infectious amyloid disease without clinical scrapie
-
Chesebro B., et al. Anchorless prion protein results in infectious amyloid disease without clinical scrapie. Science 308 (2005) 1435-1439
-
(2005)
Science
, vol.308
, pp. 1435-1439
-
-
Chesebro, B.1
-
59
-
-
20344406271
-
Cell biology. Prion toxicity: all sail and no anchor
-
Aguzzi A. Cell biology. Prion toxicity: all sail and no anchor. Science 308 (2005) 1420-1421
-
(2005)
Science
, vol.308
, pp. 1420-1421
-
-
Aguzzi, A.1
-
60
-
-
61349201380
-
Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers
-
Lauren J., Gimbel D.A., Nygaard H.B., Gilbert J.W., and Strittmatter S.M. Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers. Nature 457 (2009) 1128-1132
-
(2009)
Nature
, vol.457
, pp. 1128-1132
-
-
Lauren, J.1
Gimbel, D.A.2
Nygaard, H.B.3
Gilbert, J.W.4
Strittmatter, S.M.5
-
61
-
-
61349138103
-
Alzheimer's disease: a prion protein connection
-
Cisse M., and Mucke L. Alzheimer's disease: a prion protein connection. Nature 457 (2009) 1090-1091
-
(2009)
Nature
, vol.457
, pp. 1090-1091
-
-
Cisse, M.1
Mucke, L.2
-
62
-
-
0025212147
-
Cellular isoform of the scrapie agent protein participates in lymphocyte activation
-
Cashman N.R., Loertscher R., Nalbantoglu J., Shaw I., Kascsak R.J., Bolton D.C., and Bendheim P.E. Cellular isoform of the scrapie agent protein participates in lymphocyte activation. Cell 61 (1990) 185-192
-
(1990)
Cell
, vol.61
, pp. 185-192
-
-
Cashman, N.R.1
Loertscher, R.2
Nalbantoglu, J.3
Shaw, I.4
Kascsak, R.J.5
Bolton, D.C.6
Bendheim, P.E.7
-
63
-
-
33744905327
-
Functional implication of cellular prion protein in antigen-driven interactions between T cells and dendritic cells
-
Ballerini C., et al. Functional implication of cellular prion protein in antigen-driven interactions between T cells and dendritic cells. J. Immunol. 176 (2006) 7254-7262
-
(2006)
J. Immunol.
, vol.176
, pp. 7254-7262
-
-
Ballerini, C.1
-
64
-
-
33644839257
-
Overexpression of cellular prion protein induces an antioxidant environment altering T cell development in the thymus
-
Jouvin-Marche E., et al. Overexpression of cellular prion protein induces an antioxidant environment altering T cell development in the thymus. J. Immunol. 176 (2006) 3490-3497
-
(2006)
J. Immunol.
, vol.176
, pp. 3490-3497
-
-
Jouvin-Marche, E.1
-
65
-
-
65449161728
-
Perturbation of T-cell development by insertional mutation of a PrP transgene
-
Zabel M., Greenwood C., Thackray A.M., Pulford B., Rens W., and Bujdoso R. Perturbation of T-cell development by insertional mutation of a PrP transgene. Immunology 127 (2009) 226-236
-
(2009)
Immunology
, vol.127
, pp. 226-236
-
-
Zabel, M.1
Greenwood, C.2
Thackray, A.M.3
Pulford, B.4
Rens, W.5
Bujdoso, R.6
-
66
-
-
14644399854
-
The cellular prion protein modulates phagocytosis and inflammatory response
-
de Almeida C.J., Chiarini L.B., da Silva J.P., PM E.S., Martins M.A., and Linden R. The cellular prion protein modulates phagocytosis and inflammatory response. J. Leukoc. Biol. 77 (2009) 238-246
-
(2009)
J. Leukoc. Biol.
, vol.77
, pp. 238-246
-
-
de Almeida, C.J.1
Chiarini, L.B.2
da Silva, J.P.3
PM, E.S.4
Martins, M.A.5
Linden, R.6
-
67
-
-
0037477612
-
Cellular prion protein promotes Brucella infection into macrophages
-
Watarai M., Kim S., Erdenebaatar J., Makino S., Horiuchi M., Shirahata T., Sakaguchi S., and Katamine S. Cellular prion protein promotes Brucella infection into macrophages. J. Exp. Med. 198 (2003) 5-17
-
(2003)
J. Exp. Med.
, vol.198
, pp. 5-17
-
-
Watarai, M.1
Kim, S.2
Erdenebaatar, J.3
Makino, S.4
Horiuchi, M.5
Shirahata, T.6
Sakaguchi, S.7
Katamine, S.8
-
68
-
-
0038491424
-
Dangerous liaisons between a microbe and the prion protein
-
Aguzzi A., and Hardt W.D. Dangerous liaisons between a microbe and the prion protein. J. Exp. Med. 198 (2003) 1-4
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1-4
-
-
Aguzzi, A.1
Hardt, W.D.2
-
69
-
-
25444516224
-
Absence of evidence for the participation of the macrophage cellular prion protein in infection with Brucella suis
-
Fontes P., Alvarez-Martinez M.T., Gross A., Carnaud C., Kohler S., and Liautard J.P. Absence of evidence for the participation of the macrophage cellular prion protein in infection with Brucella suis. Infect. Immun. 73 (2005) 6229-6236
-
(2005)
Infect. Immun.
, vol.73
, pp. 6229-6236
-
-
Fontes, P.1
Alvarez-Martinez, M.T.2
Gross, A.3
Carnaud, C.4
Kohler, S.5
Liautard, J.P.6
-
70
-
-
33144456321
-
Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal
-
Zhang C.C., Steele A.D., Lindquist S., and Lodish H.F. Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal. Proc. Natl. Acad. Sci. USA 103 (2006) 2184-2189
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 2184-2189
-
-
Zhang, C.C.1
Steele, A.D.2
Lindquist, S.3
Lodish, H.F.4
-
71
-
-
43149121009
-
The prion protein knockout mouse: a phenotype under challenge
-
Steele A.D., Lindquist S., and Aguzzi A. The prion protein knockout mouse: a phenotype under challenge. Prion 1 (2007) 83-93
-
(2007)
Prion
, vol.1
, pp. 83-93
-
-
Steele, A.D.1
Lindquist, S.2
Aguzzi, A.3
-
72
-
-
1442302400
-
Murine scrapie infection causes an abnormal germinal centre reaction in the spleen
-
McGovern G., Brown K.L., Bruce M.E., and Jeffrey M. Murine scrapie infection causes an abnormal germinal centre reaction in the spleen. J. Comp. Pathol. 130 (2004) 181-194
-
(2004)
J. Comp. Pathol.
, vol.130
, pp. 181-194
-
-
McGovern, G.1
Brown, K.L.2
Bruce, M.E.3
Jeffrey, M.4
-
73
-
-
0015026826
-
Multiplication of scrapie agent in mouse spleen
-
Clarke M.C., and Haig D.A. Multiplication of scrapie agent in mouse spleen. Res. Vet. Sci. 12 (1971) 195-197
-
(1971)
Res. Vet. Sci.
, vol.12
, pp. 195-197
-
-
Clarke, M.C.1
Haig, D.A.2
-
74
-
-
0024519176
-
The role of the spleen in the neuroinvasion of scrapie in mice
-
Kimberlin R.H., and Walker C.A. The role of the spleen in the neuroinvasion of scrapie in mice. Virus Res. 12 (1989) 201-211
-
(1989)
Virus Res.
, vol.12
, pp. 201-211
-
-
Kimberlin, R.H.1
Walker, C.A.2
-
75
-
-
0022629053
-
Pathogenesis of scrapie (strain 263K) in hamsters infected intracerebrally, intraperitoneally or intraocularly
-
Kimberlin R.H., and Walker C.A. Pathogenesis of scrapie (strain 263K) in hamsters infected intracerebrally, intraperitoneally or intraocularly. J. Gen. Virol. 67 (1986) 255-263
-
(1986)
J. Gen. Virol.
, vol.67
, pp. 255-263
-
-
Kimberlin, R.H.1
Walker, C.A.2
-
76
-
-
0023095066
-
Lack of effect of thymus and spleen on the incubation period of Creutzfeldt-Jakob disease in mice
-
Mohri S., Handa S., and Tateishi J. Lack of effect of thymus and spleen on the incubation period of Creutzfeldt-Jakob disease in mice. J. Gen. Virol. 68 (1987) 1187-1189
-
(1987)
J. Gen. Virol.
, vol.68
, pp. 1187-1189
-
-
Mohri, S.1
Handa, S.2
Tateishi, J.3
-
77
-
-
0017877789
-
Transmission of Creutzfeldt-Jakob disease with scrapie-like syndromes to mice
-
Manuelidis E.E., Gorgacz E.J., and Manuelidis L. Transmission of Creutzfeldt-Jakob disease with scrapie-like syndromes to mice. Nature 271 (1978) 778-779
-
(1978)
Nature
, vol.271
, pp. 778-779
-
-
Manuelidis, E.E.1
Gorgacz, E.J.2
Manuelidis, L.3
-
78
-
-
0015301828
-
Isolation from mouse spleen of cell populations with high specific infectivity for scrapie virus
-
Lavelle G.C., Sturman L., and Hadlow W.J. Isolation from mouse spleen of cell populations with high specific infectivity for scrapie virus. Infect. Immun. 5 (1972) 319-323
-
(1972)
Infect. Immun.
, vol.5
, pp. 319-323
-
-
Lavelle, G.C.1
Sturman, L.2
Hadlow, W.J.3
-
79
-
-
0021212843
-
Pathogenesis of mouse scrapie: distribution of agent in the pulp and stroma of infected spleens
-
Clarke M.C., and Kimberlin R.H. Pathogenesis of mouse scrapie: distribution of agent in the pulp and stroma of infected spleens. Vet. Microbiol. 9 (1984) 215-225
-
(1984)
Vet. Microbiol.
, vol.9
, pp. 215-225
-
-
Clarke, M.C.1
Kimberlin, R.H.2
-
80
-
-
0023094630
-
Ionising radiation has no influence on scrapie incubation period in mice
-
Fraser H., and Farquhar C.F. Ionising radiation has no influence on scrapie incubation period in mice. Vet. Microbiol. 13 (1987) 211-223
-
(1987)
Vet. Microbiol.
, vol.13
, pp. 211-223
-
-
Fraser, H.1
Farquhar, C.F.2
-
81
-
-
0034953560
-
Efficient lymphoreticular prion propagation requires PrP(c) in stromal and hematopoietic cells
-
Kaeser P.S., Klein M.A., Schwarz P., and Aguzzi A. Efficient lymphoreticular prion propagation requires PrP(c) in stromal and hematopoietic cells. J. Virol. 75 (2001) 7097-7106
-
(2001)
J. Virol.
, vol.75
, pp. 7097-7106
-
-
Kaeser, P.S.1
Klein, M.A.2
Schwarz, P.3
Aguzzi, A.4
-
82
-
-
0038186806
-
PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain
-
Blättler T., Brandner S., Raeber A.J., Klein M.A., Voigtländer T., Weissmann C., and Aguzzi A. PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain. Nature 389 (1997) 69-73
-
(1997)
Nature
, vol.389
, pp. 69-73
-
-
Blättler, T.1
Brandner, S.2
Raeber, A.J.3
Klein, M.A.4
Voigtländer, T.5
Weissmann, C.6
Aguzzi, A.7
-
83
-
-
33751098243
-
Early and rapid engraftment of bone marrow-derived microglia in scrapie
-
Priller J., Prinz M., Heikenwalder M., Zeller N., Schwarz P., and Aguzzi A. Early and rapid engraftment of bone marrow-derived microglia in scrapie. J. Neuorsci. 26 (2006) 11753-11762
-
(2006)
J. Neuorsci.
, vol.26
, pp. 11753-11762
-
-
Priller, J.1
Prinz, M.2
Heikenwalder, M.3
Zeller, N.4
Schwarz, P.5
Aguzzi, A.6
-
84
-
-
0031444295
-
A crucial role for B cells in neuroinvasive scrapie
-
Klein M.A., et al. A crucial role for B cells in neuroinvasive scrapie. Nature 390 (1997) 687-690
-
(1997)
Nature
, vol.390
, pp. 687-690
-
-
Klein, M.A.1
-
85
-
-
0031759918
-
PrP expression in B lymphocytes is not required for prion neuroinvasion
-
Klein M.A., Frigg R., Raeber A.J., Flechsig E., Hegyi I., Zinkernagel R.M., Weissmann C., and Aguzzi A. PrP expression in B lymphocytes is not required for prion neuroinvasion. Nat. Med. 4 (1998) 1429-1433
-
(1998)
Nat. Med.
, vol.4
, pp. 1429-1433
-
-
Klein, M.A.1
Frigg, R.2
Raeber, A.J.3
Flechsig, E.4
Hegyi, I.5
Zinkernagel, R.M.6
Weissmann, C.7
Aguzzi, A.8
-
86
-
-
0035957340
-
B lymphocyte-restricted expression of prion protein does not enable prion replication in prion protein knockout mice
-
Montrasio F., et al. B lymphocyte-restricted expression of prion protein does not enable prion replication in prion protein knockout mice. Proc. Natl. Acad. Sci. USA 98 (2001) 4034-4037
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 4034-4037
-
-
Montrasio, F.1
-
87
-
-
0025983158
-
Abnormal isoform of prion protein accumulates in follicular dendritic cells in mice with Creutzfeldt-Jakob disease
-
Kitamoto T., Muramoto T., Mohri S., Doh ura K., and Tateishi J. Abnormal isoform of prion protein accumulates in follicular dendritic cells in mice with Creutzfeldt-Jakob disease. J. Virol. 65 (1991) 6292-6295
-
(1991)
J. Virol.
, vol.65
, pp. 6292-6295
-
-
Kitamoto, T.1
Muramoto, T.2
Mohri, S.3
Doh ura, K.4
Tateishi, J.5
-
88
-
-
47249139528
-
Inhibition of the lymphotoxin pathway as a therapy for autoimmune disease
-
Browning J.L. Inhibition of the lymphotoxin pathway as a therapy for autoimmune disease. Immunol. Rev. 223 (2008) 202-220
-
(2008)
Immunol. Rev.
, vol.223
, pp. 202-220
-
-
Browning, J.L.1
-
89
-
-
0034686002
-
Impaired prion replication in spleens of mice lacking functional follicular dendritic cells
-
Montrasio F., Frigg R., Glatzel M., Klein M.A., Mackay F., Aguzzi A., and Weissmann C. Impaired prion replication in spleens of mice lacking functional follicular dendritic cells. Science 288 (2000) 1257-1259
-
(2000)
Science
, vol.288
, pp. 1257-1259
-
-
Montrasio, F.1
Frigg, R.2
Glatzel, M.3
Klein, M.A.4
Mackay, F.5
Aguzzi, A.6
Weissmann, C.7
-
90
-
-
45149087942
-
Follicular dendritic cells control engulfment of apoptotic bodies by secreting Mfge8
-
Kranich J., et al. Follicular dendritic cells control engulfment of apoptotic bodies by secreting Mfge8. J. Exp. Med. 205 (2008) 1293-1302
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1293-1302
-
-
Kranich, J.1
-
91
-
-
0035047889
-
Complement facilitates early prion pathogenesis
-
Klein M.A., et al. Complement facilitates early prion pathogenesis. Nat. Med. 7 (2001) 488-492
-
(2001)
Nat. Med.
, vol.7
, pp. 488-492
-
-
Klein, M.A.1
-
92
-
-
0035053039
-
Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie
-
Mabbott N.A., Bruce M.E., Botto M., Walport M.J., and Pepys M.B. Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie. Nat. Med. 7 (2001) 485-487
-
(2001)
Nat. Med.
, vol.7
, pp. 485-487
-
-
Mabbott, N.A.1
Bruce, M.E.2
Botto, M.3
Walport, M.J.4
Pepys, M.B.5
-
93
-
-
38449119141
-
Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis
-
Zabel M.D., et al. Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis. J. Immunol. 179 (2007) 6144-6152
-
(2007)
J. Immunol.
, vol.179
, pp. 6144-6152
-
-
Zabel, M.D.1
-
94
-
-
0023736747
-
Noradrenergic sympathetic innervation of lymphoid organs
-
Felten S.Y., Felten D.L., Bellinger D.L., Carlson S.L., Ackerman K.D., Madden K.S., Olschowka J.A., and Livnat S. Noradrenergic sympathetic innervation of lymphoid organs. Prog Allergy 43 (1988) 14-36
-
(1988)
Prog Allergy
, vol.43
, pp. 14-36
-
-
Felten, S.Y.1
Felten, D.L.2
Bellinger, D.L.3
Carlson, S.L.4
Ackerman, K.D.5
Madden, K.S.6
Olschowka, J.A.7
Livnat, S.8
-
95
-
-
0021808813
-
Pathogenesis of mouse scrapie: dynamics of vacuolation in brain and spinal cord after intraperitoneal infection
-
Cole S., and Kimberlin R.H. Pathogenesis of mouse scrapie: dynamics of vacuolation in brain and spinal cord after intraperitoneal infection. Neuropathol. Appl. Neurobiol. 11 (1985) 213-227
-
(1985)
Neuropathol. Appl. Neurobiol.
, vol.11
, pp. 213-227
-
-
Cole, S.1
Kimberlin, R.H.2
-
96
-
-
0033574604
-
Pathological PrP is abundant in sympathetic and sensory ganglia of hamsters fed with scrapie
-
McBride P.A., and Beekes M. Pathological PrP is abundant in sympathetic and sensory ganglia of hamsters fed with scrapie. Neurosci. Lett. 265 (1999) 135-138
-
(1999)
Neurosci. Lett.
, vol.265
, pp. 135-138
-
-
McBride, P.A.1
Beekes, M.2
-
97
-
-
0141573165
-
The sympathetic nervous system is involved in variant Creutzfeldt-Jakob disease
-
Haik S., Faucheux B.A., Sazdovitch V., Privat N., Kemeny J.L., Perret-Liaudet A., and Hauw J.J. The sympathetic nervous system is involved in variant Creutzfeldt-Jakob disease. Nat Med 9 (2003) 1121-1122
-
(2003)
Nat Med
, vol.9
, pp. 1121-1122
-
-
Haik, S.1
Faucheux, B.A.2
Sazdovitch, V.3
Privat, N.4
Kemeny, J.L.5
Perret-Liaudet, A.6
Hauw, J.J.7
-
98
-
-
0034891027
-
Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion
-
Glatzel M., Heppner F.L., Albers K.M., and Aguzzi A. Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion. Neuron 31 (2001) 25-34
-
(2001)
Neuron
, vol.31
, pp. 25-34
-
-
Glatzel, M.1
Heppner, F.L.2
Albers, K.M.3
Aguzzi, A.4
-
99
-
-
0033763178
-
PrP(C) expression in the peripheral nervous system is a determinant of prion neuroinvasion
-
Glatzel M., and Aguzzi A. PrP(C) expression in the peripheral nervous system is a determinant of prion neuroinvasion. J. Gen. Virol. 81 (2000) 2813-2821
-
(2000)
J. Gen. Virol.
, vol.81
, pp. 2813-2821
-
-
Glatzel, M.1
Aguzzi, A.2
-
101
-
-
0242499506
-
Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion
-
Prinz M., et al. Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion. Nature 425 (2003) 957-962
-
(2003)
Nature
, vol.425
, pp. 957-962
-
-
Prinz, M.1
-
102
-
-
0030582773
-
A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen
-
Forster R., Mattis A.E., Kremmer E., Wolf E., Brem G., and Lipp M. A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell 87 (1996) 1037-1047
-
(1996)
Cell
, vol.87
, pp. 1037-1047
-
-
Forster, R.1
Mattis, A.E.2
Kremmer, E.3
Wolf, E.4
Brem, G.5
Lipp, M.6
-
103
-
-
0033987269
-
Early accumulation of pathological PrP in the enteric nervous system and gut-associated lymphoid tissue of hamsters orally infected with scrapie
-
Beekes M., and McBride P.A. Early accumulation of pathological PrP in the enteric nervous system and gut-associated lymphoid tissue of hamsters orally infected with scrapie. Neurosci. Lett. 278 (2000) 181-184
-
(2000)
Neurosci. Lett.
, vol.278
, pp. 181-184
-
-
Beekes, M.1
McBride, P.A.2
-
104
-
-
0038618854
-
Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility
-
Mabbott N.A., Young J., McConnell I., and Bruce M.E. Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility. J. Virol. 77 (2003) 6845-6854
-
(2003)
J. Virol.
, vol.77
, pp. 6845-6854
-
-
Mabbott, N.A.1
Young, J.2
McConnell, I.3
Bruce, M.E.4
-
105
-
-
36749084554
-
Germinal center B cells are dispensable in prion transport and neuroinvasion
-
Heikenwalder M., et al. Germinal center B cells are dispensable in prion transport and neuroinvasion. J. Neuroimmunol. 192 (2007) 113-123
-
(2007)
J. Neuroimmunol.
, vol.192
, pp. 113-123
-
-
Heikenwalder, M.1
-
106
-
-
0034798246
-
Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie
-
Aucouturier P., Geissmann F., Damotte D., Saborio G.P., Meeker H.C., Kascsak R., Carp R.I., and Wisniewski T. Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie. J. Clin. Invest. 108 (2001) 703-708
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 703-708
-
-
Aucouturier, P.1
Geissmann, F.2
Damotte, D.3
Saborio, G.P.4
Meeker, H.C.5
Kascsak, R.6
Carp, R.I.7
Wisniewski, T.8
-
107
-
-
34347236155
-
Assessing the involvement of migratory dendritic cells in the transfer of the scrapie agent from the immune to peripheral nervous systems
-
Raymond C.R., and Mabbott N.A. Assessing the involvement of migratory dendritic cells in the transfer of the scrapie agent from the immune to peripheral nervous systems. J. Neuroimmunol. 187 (2007) 114-125
-
(2007)
J. Neuroimmunol.
, vol.187
, pp. 114-125
-
-
Raymond, C.R.1
Mabbott, N.A.2
-
108
-
-
0032746253
-
Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells
-
Brown K.L., Stewart K., Ritchie D.L., Mabbott N.A., Williams A., Fraser H., Morrison W.I., and Bruce M.E. Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells. Nat. Med. 5 (1999) 1308-1312
-
(1999)
Nat. Med.
, vol.5
, pp. 1308-1312
-
-
Brown, K.L.1
Stewart, K.2
Ritchie, D.L.3
Mabbott, N.A.4
Williams, A.5
Fraser, H.6
Morrison, W.I.7
Bruce, M.E.8
-
109
-
-
0037154263
-
Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells
-
Prinz M., Montrasio F., Klein M.A., Schwarz P., Priller J., Odermatt B., Pfeffer K., and Aguzzi A. Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells. Proc. Natl. Acad. Sci. USA 99 (2002) 919-924
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 919-924
-
-
Prinz, M.1
Montrasio, F.2
Klein, M.A.3
Schwarz, P.4
Priller, J.5
Odermatt, B.6
Pfeffer, K.7
Aguzzi, A.8
-
110
-
-
0036237549
-
Temporary blockade of the tumor necrosis factor receptor signaling pathway impedes the spread of scrapie to the brain
-
Mabbott N.A., McGovern G., Jeffrey M., and Bruce M.E. Temporary blockade of the tumor necrosis factor receptor signaling pathway impedes the spread of scrapie to the brain. J. Virol. 76 (2002) 5131-5139
-
(2002)
J. Virol.
, vol.76
, pp. 5131-5139
-
-
Mabbott, N.A.1
McGovern, G.2
Jeffrey, M.3
Bruce, M.E.4
-
111
-
-
13244268542
-
Experimental transmission of sheep scrapie by intracerebral and oral routes to genetically susceptible Suffolk sheep in the United States
-
Hamir A.N., Kunkle R.A., Richt J.A., Miller J.M., Cutlip R.C., and Jenny A.L. Experimental transmission of sheep scrapie by intracerebral and oral routes to genetically susceptible Suffolk sheep in the United States. J. Vet. Diagn. Invest. 17 (2005) 3-9
-
(2005)
J. Vet. Diagn. Invest.
, vol.17
, pp. 3-9
-
-
Hamir, A.N.1
Kunkle, R.A.2
Richt, J.A.3
Miller, J.M.4
Cutlip, R.C.5
Jenny, A.L.6
-
112
-
-
0032480316
-
Turning off follicular dendritic cells
-
Mackay F., and Browning J.L. Turning off follicular dendritic cells. Nature 395 (1998) 26-27
-
(1998)
Nature
, vol.395
, pp. 26-27
-
-
Mackay, F.1
Browning, J.L.2
-
113
-
-
34247585476
-
Prion infection of muscle cells in vitro
-
Dlakic W.M., Grigg E., and Bessen R.A. Prion infection of muscle cells in vitro. J. Virol. 81 (2007) 4615-4624
-
(2007)
J. Virol.
, vol.81
, pp. 4615-4624
-
-
Dlakic, W.M.1
Grigg, E.2
Bessen, R.A.3
-
114
-
-
0036230174
-
Lymphotoxin-alpha- and lymphotoxin-beta-deficient mice differ in susceptibility to scrapie: evidence against dendritic cell involvement in neuroinvasion
-
Oldstone M.B., et al. Lymphotoxin-alpha- and lymphotoxin-beta-deficient mice differ in susceptibility to scrapie: evidence against dendritic cell involvement in neuroinvasion. J. Virol. 76 (2002) 4357-4363
-
(2002)
J. Virol.
, vol.76
, pp. 4357-4363
-
-
Oldstone, M.B.1
-
115
-
-
0033102301
-
A novel epitope for the specific detection of exogenous prion proteins in transgenic mice and transfected murine cell lines
-
Vorberg I., Buschmann A., Harmeyer S., Saalm ller A., Pfaff E., and Groschup M.H. A novel epitope for the specific detection of exogenous prion proteins in transgenic mice and transfected murine cell lines. Virology 255 (1999) 26-31
-
(1999)
Virology
, vol.255
, pp. 26-31
-
-
Vorberg, I.1
Buschmann, A.2
Harmeyer, S.3
Saalm ller, A.4
Pfaff, E.5
Groschup, M.H.6
-
116
-
-
38049170555
-
Prion strain discrimination in cell culture: the cell panel assay
-
Mahal S.P., Baker C.A., Demczyk C.A., Smith E.W., Julius C., and Weissmann C. Prion strain discrimination in cell culture: the cell panel assay. Proc. Natl. Acad. Sci. USA 104 (2007) 20908-20913
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 20908-20913
-
-
Mahal, S.P.1
Baker, C.A.2
Demczyk, C.A.3
Smith, E.W.4
Julius, C.5
Weissmann, C.6
-
117
-
-
57449112742
-
Lymphotoxin-dependent prion replication in inflammatory stromal cells of granulomas
-
Heikenwalder M., et al. Lymphotoxin-dependent prion replication in inflammatory stromal cells of granulomas. Immunity 29 (2008) 998-1008
-
(2008)
Immunity
, vol.29
, pp. 998-1008
-
-
Heikenwalder, M.1
-
118
-
-
34249662650
-
Accumulation of pathological prion protein PrPSc in the skin of animals with experimental and natural scrapie
-
Thomzig A., Schulz-Schaeffer W., Wrede A., Wemheuer W., Brenig B., Kratzel C., Lemmer K., and Beekes M. Accumulation of pathological prion protein PrPSc in the skin of animals with experimental and natural scrapie. PLoS Pathog. 3 (2007) e66
-
(2007)
PLoS Pathog.
, vol.3
-
-
Thomzig, A.1
Schulz-Schaeffer, W.2
Wrede, A.3
Wemheuer, W.4
Brenig, B.5
Kratzel, C.6
Lemmer, K.7
Beekes, M.8
-
119
-
-
4544224048
-
Antiprion immunotherapy: to suppress or to stimulate?
-
Aguzzi A., and Sigurdson C.J. Antiprion immunotherapy: to suppress or to stimulate?. Nat. Rev. Immunol. 4 (2004) 725-736
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 725-736
-
-
Aguzzi, A.1
Sigurdson, C.J.2
-
120
-
-
0037143011
-
Postexposure prophylaxis against prion disease with a stimulator of innate immunity
-
Sethi S., Lipford G., Wagner H., and Kretzschmar H. Postexposure prophylaxis against prion disease with a stimulator of innate immunity. Lancet 360 (2002) 229-230
-
(2002)
Lancet
, vol.360
, pp. 229-230
-
-
Sethi, S.1
Lipford, G.2
Wagner, H.3
Kretzschmar, H.4
-
121
-
-
0037297956
-
Prion pathogenesis in the absence of Toll-like receptor signalling
-
Prinz M., Heikenwalder M., Schwarz P., Takeda K., Akira S., and Aguzzi A. Prion pathogenesis in the absence of Toll-like receptor signalling. EMBO Rep. 4 (2003) 195-199
-
(2003)
EMBO Rep.
, vol.4
, pp. 195-199
-
-
Prinz, M.1
Heikenwalder, M.2
Schwarz, P.3
Takeda, K.4
Akira, S.5
Aguzzi, A.6
-
122
-
-
0842343142
-
Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration
-
Heikenwalder M., Polymenidou M., Junt T., Sigurdson C., Wagner H., Akira S., Zinkernagel R., and Aguzzi A. Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration. Nat. Med. 10 (2004) 187-192
-
(2004)
Nat. Med.
, vol.10
, pp. 187-192
-
-
Heikenwalder, M.1
Polymenidou, M.2
Junt, T.3
Sigurdson, C.4
Wagner, H.5
Akira, S.6
Zinkernagel, R.7
Aguzzi, A.8
-
124
-
-
0033564204
-
Specific binding of normal prion protein to the scrapie form via a localized domain initiates its conversion to the protease-resistant state
-
Horiuchi M., and Caughey B. Specific binding of normal prion protein to the scrapie form via a localized domain initiates its conversion to the protease-resistant state. EMBO J. 18 (1999) 3193-3203
-
(1999)
EMBO J.
, vol.18
, pp. 3193-3203
-
-
Horiuchi, M.1
Caughey, B.2
-
125
-
-
0035979274
-
Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody
-
Enari M., Flechsig E., and Weissmann C. Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody. Proc. Natl. Acad. Sci. USA 98 (2001) 9295-9299
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9295-9299
-
-
Enari, M.1
Flechsig, E.2
Weissmann, C.3
-
126
-
-
0035899413
-
Antibodies inhibit prion propagation and clear cell cultures of prion infectivity
-
Peretz D., et al. Antibodies inhibit prion propagation and clear cell cultures of prion infectivity. Nature 412 (2001) 739-743
-
(2001)
Nature
, vol.412
, pp. 739-743
-
-
Peretz, D.1
-
127
-
-
0035812752
-
Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies
-
Heppner F.L., et al. Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies. Science 294 (2001) 178-182
-
(2001)
Science
, vol.294
, pp. 178-182
-
-
Heppner, F.L.1
-
128
-
-
0036317750
-
Immunization delays the onset of prion disease in mice
-
Sigurdsson E.M., et al. Immunization delays the onset of prion disease in mice. Am. J. Pathol. 161 (2002) 13-17
-
(2002)
Am. J. Pathol.
, vol.161
, pp. 13-17
-
-
Sigurdsson, E.M.1
-
129
-
-
4444325310
-
Humoral immune response to native eukaryotic prion protein correlates with anti-prion protection
-
Polymenidou M., et al. Humoral immune response to native eukaryotic prion protein correlates with anti-prion protection. Proc. Natl. Acad. Sci. USA 101 (2004) 14670-14676
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 14670-14676
-
-
Polymenidou, M.1
-
130
-
-
43049165807
-
High titers of mucosal and systemic anti-PrP antibodies abrogate oral prion infection in mucosal-vaccinated mice
-
Goni F., et al. High titers of mucosal and systemic anti-PrP antibodies abrogate oral prion infection in mucosal-vaccinated mice. Neuroscience 153 (2008) 679-686
-
(2008)
Neuroscience
, vol.153
, pp. 679-686
-
-
Goni, F.1
-
131
-
-
0037422133
-
Monoclonal antibodies inhibit prion replication and delay the development of prion disease
-
White A.R., et al. Monoclonal antibodies inhibit prion replication and delay the development of prion disease. Nature 422 (2003) 80-83
-
(2003)
Nature
, vol.422
, pp. 80-83
-
-
White, A.R.1
-
132
-
-
12144291519
-
Cross-linking cellular prion protein triggers neuronal apoptosis in vivo
-
Solforosi L., et al. Cross-linking cellular prion protein triggers neuronal apoptosis in vivo. Science 303 (2004) 1514-1516
-
(2004)
Science
, vol.303
, pp. 1514-1516
-
-
Solforosi, L.1
-
133
-
-
0020639765
-
In vitro propagation of the scrapie agent. I. Transformation of mouse glia and neuroblastoma cells after infection with the mouse-adapted scrapie strain c-506
-
Markovits P., Dautheville C., Dormont D., Dianoux L., and Latarjet R. In vitro propagation of the scrapie agent. I. Transformation of mouse glia and neuroblastoma cells after infection with the mouse-adapted scrapie strain c-506. Acta Neuropathol. Berl. 60 (1983) 75-80
-
(1983)
Acta Neuropathol. Berl.
, vol.60
, pp. 75-80
-
-
Markovits, P.1
Dautheville, C.2
Dormont, D.3
Dianoux, L.4
Latarjet, R.5
-
134
-
-
0023091197
-
Characterization of scrapie infection in mouse neuroblastoma cells
-
Race R.E., Fadness L.H., and Chesebro B. Characterization of scrapie infection in mouse neuroblastoma cells. J. Gen. Virol. 68 (1987) 1391-1399
-
(1987)
J. Gen. Virol.
, vol.68
, pp. 1391-1399
-
-
Race, R.E.1
Fadness, L.H.2
Chesebro, B.3
-
135
-
-
0033988236
-
Successful transmission of three mouse-adapted scrapie strains to murine neuroblastoma cell lines overexpressing wild-type mouse prion protein
-
Nishida N., et al. Successful transmission of three mouse-adapted scrapie strains to murine neuroblastoma cell lines overexpressing wild-type mouse prion protein. J. Virol. 74 (2000) 320-325
-
(2000)
J. Virol.
, vol.74
, pp. 320-325
-
-
Nishida, N.1
-
136
-
-
0028967732
-
Proteinase-resistant protein in human neuroblastoma cells infected with brain material from Creutzfeldt-Jakob patient
-
Ladogana A., Liu Q., Xi Y.G., and Pocchiari M. Proteinase-resistant protein in human neuroblastoma cells infected with brain material from Creutzfeldt-Jakob patient. Lancet 345 (1995) 594-595
-
(1995)
Lancet
, vol.345
, pp. 594-595
-
-
Ladogana, A.1
Liu, Q.2
Xi, Y.G.3
Pocchiari, M.4
-
137
-
-
0021745705
-
In vitro replication of scrapie agent in a neuronal model: infection of PC12 cells
-
Rubenstein R., Carp R.I., and Callahan S.M. In vitro replication of scrapie agent in a neuronal model: infection of PC12 cells. J. Gen. Virol. 65 (1984) 2191-2198
-
(1984)
J. Gen. Virol.
, vol.65
, pp. 2191-2198
-
-
Rubenstein, R.1
Carp, R.I.2
Callahan, S.M.3
-
138
-
-
0037611374
-
A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis
-
Schätzl H.M., Laszlo L., Holtzman D.M., Tatzelt J., DeArmond S.J., Weiner R.I., Mobley W.C., and Prusiner S.B. A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis. J. Virol. 71 (1997) 8821-8831
-
(1997)
J. Virol.
, vol.71
, pp. 8821-8831
-
-
Schätzl, H.M.1
Laszlo, L.2
Holtzman, D.M.3
Tatzelt, J.4
DeArmond, S.J.5
Weiner, R.I.6
Mobley, W.C.7
Prusiner, S.B.8
-
139
-
-
33144469836
-
Mouse-adapted scrapie infection of SN56 cells: greater efficiency with microsome-associated versus purified PrP-res
-
Baron G.S., Magalhaes A.C., Prado M.A., and Caughey B. Mouse-adapted scrapie infection of SN56 cells: greater efficiency with microsome-associated versus purified PrP-res. J. Virol. 80 (2006) 2106-2117
-
(2006)
J. Virol.
, vol.80
, pp. 2106-2117
-
-
Baron, G.S.1
Magalhaes, A.C.2
Prado, M.A.3
Caughey, B.4
-
140
-
-
34547118602
-
Scrapie infection of prion protein-deficient cell line upon ectopic expression of mutant prion proteins
-
Maas E., Geissen M., Groschup M.H., Rost R., Onodera T., Schätzl H., and Vorberg I.M. Scrapie infection of prion protein-deficient cell line upon ectopic expression of mutant prion proteins. J.Biol. Chem. 282 (2007) 18702-18710
-
(2007)
J.Biol. Chem.
, vol.282
, pp. 18702-18710
-
-
Maas, E.1
Geissen, M.2
Groschup, M.H.3
Rost, R.4
Onodera, T.5
Schätzl, H.6
Vorberg, I.M.7
-
141
-
-
4344628202
-
Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death
-
Cronier S., Laude H., and Peyrin J.M. Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death. Proc. Natl. Acad. Sci. USA. 101 (2004) 12271-12276
-
(2004)
Proc. Natl. Acad. Sci. USA.
, vol.101
, pp. 12271-12276
-
-
Cronier, S.1
Laude, H.2
Peyrin, J.M.3
-
143
-
-
0014930651
-
Evidence for the multiplication of scrapie agent in cell culture
-
Clarke M.C., and Haig D.A. Evidence for the multiplication of scrapie agent in cell culture. Nature 225 (1970) 100-101
-
(1970)
Nature
, vol.225
, pp. 100-101
-
-
Clarke, M.C.1
Haig, D.A.2
-
144
-
-
0035796463
-
Scrapie strains maintain biological phenotypes on propagation in a cell line in culture
-
Birkett C.R., Hennion R.M., Bembridge D.A., Clarke M.C., Chree A., Bruce M.E., and Bostock C.J. Scrapie strains maintain biological phenotypes on propagation in a cell line in culture. EMBO J. 20 (2001) 3351-3358
-
(2001)
EMBO J.
, vol.20
, pp. 3351-3358
-
-
Birkett, C.R.1
Hennion, R.M.2
Bembridge, D.A.3
Clarke, M.C.4
Chree, A.5
Bruce, M.E.6
Bostock, C.J.7
-
145
-
-
0017143089
-
Infection of a cell line of mouse L fibroblasts with scrapie agent
-
Clarke M.C., and Millson G.C. Infection of a cell line of mouse L fibroblasts with scrapie agent. Nature 261 (1976) 144-145
-
(1976)
Nature
, vol.261
, pp. 144-145
-
-
Clarke, M.C.1
Millson, G.C.2
-
147
-
-
1142285202
-
Susceptibility of common fibroblast cell lines to transmissible spongiform encephalopathy agents
-
Vorberg I., Raines A., Story B., and Priola S.A. Susceptibility of common fibroblast cell lines to transmissible spongiform encephalopathy agents. J. Infect. Dis. 189 (2004) 431-439
-
(2004)
J. Infect. Dis.
, vol.189
, pp. 431-439
-
-
Vorberg, I.1
Raines, A.2
Story, B.3
Priola, S.A.4
-
148
-
-
34250142721
-
Attempts to establish the scrapie agent in cell lines
-
Elleman C.J. Attempts to establish the scrapie agent in cell lines. Vet. Res. Commun. 8 (1984) 309-316
-
(1984)
Vet. Res. Commun.
, vol.8
, pp. 309-316
-
-
Elleman, C.J.1
-
149
-
-
0023144970
-
Persistence of the scrapie agent in glial cells from rat Gasserian ganglion
-
Roikhel V.M., Fokina G.I., Lisak V.M., Kondakova L.I., Korolev M.B., and Pogodina V.V. Persistence of the scrapie agent in glial cells from rat Gasserian ganglion. Acta Virol. 31 (1987) 36-42
-
(1987)
Acta Virol.
, vol.31
, pp. 36-42
-
-
Roikhel, V.M.1
Fokina, G.I.2
Lisak, V.M.3
Kondakova, L.I.4
Korolev, M.B.5
Pogodina, V.V.6
-
150
-
-
0025373111
-
Scrapie prion proteins accumulate in the cytoplasm of persistently infected cultured cells
-
Taraboulos A., Serban D., and Prusiner S.B. Scrapie prion proteins accumulate in the cytoplasm of persistently infected cultured cells. J. Cell Biol. 110 (1990) 2117-2132
-
(1990)
J. Cell Biol.
, vol.110
, pp. 2117-2132
-
-
Taraboulos, A.1
Serban, D.2
Prusiner, S.B.3
-
151
-
-
33846530529
-
Microglial cell line established from prion protein-overexpressing mice is susceptible to various murine prion strains
-
Iwamaru T.T., Ogihara K., Hoshino M., Takata M., Imamura M., Tagawa Y., Hayashi-Kato H., Ushiki-Kaku Y., Shimizu Y., Okada H., Shinagawa M., Kitani H., and Yokoyama T. Microglial cell line established from prion protein-overexpressing mice is susceptible to various murine prion strains. J. Virol. 81 (2007) 1524-1527
-
(2007)
J. Virol.
, vol.81
, pp. 1524-1527
-
-
Iwamaru, T.T.1
Ogihara, K.2
Hoshino, M.3
Takata, M.4
Imamura, M.5
Tagawa, Y.6
Hayashi-Kato, H.7
Ushiki-Kaku, Y.8
Shimizu, Y.9
Okada, H.10
Shinagawa, M.11
Kitani, H.12
Yokoyama, T.13
-
152
-
-
0036174389
-
PrP expression and replication by Schwann cells: implications in prion spreading
-
Follet J., et al. PrP expression and replication by Schwann cells: implications in prion spreading. J. Virol. 76 (2002) 2434-2439
-
(2002)
J. Virol.
, vol.76
, pp. 2434-2439
-
-
Follet, J.1
-
153
-
-
10744231794
-
Cultured peripheral neuroglial cells are highly permissive to sheep prion infection
-
Archer F., et al. Cultured peripheral neuroglial cells are highly permissive to sheep prion infection. J. Virol. 78 (2004) 482-4890
-
(2004)
J. Virol.
, vol.78
, pp. 482-4890
-
-
Archer, F.1
-
154
-
-
30344443997
-
Inhibition of protease-resistant prion protein formation in a transformed deer cell line infected with chronic wasting disease
-
Raymond G.J., et al. Inhibition of protease-resistant prion protein formation in a transformed deer cell line infected with chronic wasting disease. J. Virol. 80 (2006) 596-604
-
(2006)
J. Virol.
, vol.80
, pp. 596-604
-
-
Raymond, G.J.1
-
155
-
-
0035957345
-
Ex vivo propagation of infectious sheep scrapie agent in heterologous epithelial cells expressing ovine prion protein
-
Vilette D., Andreoletti O., Archer F., Madelaine M.F., Vilotte J.L., Lehmann S., and Laude H. Ex vivo propagation of infectious sheep scrapie agent in heterologous epithelial cells expressing ovine prion protein. Proc. Natl. Acad. Sci. USA 98 (2001) 4055-4059
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 4055-4059
-
-
Vilette, D.1
Andreoletti, O.2
Archer, F.3
Madelaine, M.F.4
Vilotte, J.L.5
Lehmann, S.6
Laude, H.7
-
156
-
-
38349079829
-
A cell line infectible by prion strains from different species
-
Courageot M.P., et al. A cell line infectible by prion strains from different species. J. Gen. Virol. 89 (2008) 341-347
-
(2008)
J. Gen. Virol.
, vol.89
, pp. 341-347
-
-
Courageot, M.P.1
-
157
-
-
33947709328
-
Packaging of prions into exosomes is associated with a novel pathway of PrP processing
-
Vella L.J., Sharples R.A., Lawson V.A., Masters C.L., Cappai R., and Hill A.F. Packaging of prions into exosomes is associated with a novel pathway of PrP processing. J. Pathol. 211 (2007) 582-590
-
(2007)
J. Pathol.
, vol.211
, pp. 582-590
-
-
Vella, L.J.1
Sharples, R.A.2
Lawson, V.A.3
Masters, C.L.4
Cappai, R.5
Hill, A.F.6
|