Specific binding of normal prion protein to the scrapie form via a localized domain initiates its conversion to the protease-resistant state

EMBO Journal

Volumn 18, Issue 12, 1999, Pages 3193-3203

  Horiuchi, Motohiro ^a,b   Caughey, Byron ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b OBIHIRO UNIVERSITY OF AGRICULTURE AND VETERINARY MEDICINE   (Japan)

Author keywords

Cell free conversion; Prion protein; Scrapie

Indexed keywords

ANTIBODY; PRION PROTEIN;

ANTIGEN BINDING; ARTICLE; BINDING SITE; CELL FREE SYSTEM; CELL LYSATE; CONTROLLED STUDY; HAMSTER; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN MODIFICATION; PROTEIN STRUCTURE; SCRAPIE; STEREOSPECIFICITY;

ANIMALS; ANTIBODIES, MONOCLONAL; BINDING SITES; BRAIN; CARBOXYPEPTIDASES; CRICETINAE; ENDOPEPTIDASE K; ENDOPEPTIDASES; EPITOPES; GLYCOSYLATION; IMMUNOGLOBULIN FAB FRAGMENTS; MICE; MODELS, MOLECULAR; MOLECULAR WEIGHT; POTASSIUM CHLORIDE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN ISOFORMS; PRPC PROTEINS; PRPSC PROTEINS; SEQUENCE DELETION; SODIUM CHLORIDE;

EID: 0033564204     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.12.3193     Document Type: Article

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