Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 7, 1999, Pages 3987-3992

  Raeber, Alex J ^a,b   Sailer, Andreas ^a,c   Hegyi, Ivan ^b   Klein, Michael A ^b   Rülicke, Thomas ^b   Fischer, Marek ^a,b   Brandner, Sebastian ^b   Aguzzi, Adriano ^b   Weissmann, Charles ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Lymphoreticular system; Prion disease; PrP null mice; Scrapie; Transgenic mice

Indexed keywords

ALBUMIN; INTERFERON REGULATORY FACTOR 1; PRION PROTEIN;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; KNOCKOUT MOUSE; LIVER CELL; MOUSE; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RETICULOENDOTHELIAL SYSTEM; SCRAPIE; SPLEEN; T LYMPHOCYTE; THYMUS; VIRUS INFECTIVITY; VIRUS REPLICATION;

ANIMALS; BRAIN; ENHANCER ELEMENTS (GENETICS); EXONS; LIVER; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; ORGAN SPECIFICITY; PRIONS; PROMOTER REGIONS (GENETICS); REGULATORY SEQUENCES, NUCLEIC ACID; RESTRICTION MAPPING; SPLEEN; T-LYMPHOCYTES; TRANSCRIPTION, GENETIC;

ANIMALIA; DROMAIUS NOVAEHOLLANDIAE; MUS MUSCULUS;

EID: 0033616564     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.7.3987     Document Type: Article

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