-
1
-
-
0029999787
-
Alzheimer's disease hyperphosphorylated τ sequesters normal τ into tangles of filaments and disassembles microtubules
-
Alonso A.C., Grundke-Iqbal I., Iqbal K. Alzheimer's disease hyperphosphorylated τ sequesters normal τ into tangles of filaments and disassembles microtubules. Nat. Med. 2:1996;783-787.
-
(1996)
Nat. Med.
, vol.2
, pp. 783-787
-
-
Alonso, A.C.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
2
-
-
0020490156
-
Identification of a protein that purifies with the scrapie prion
-
Bolton D.C., McKinley M.P., Prusiner S.B. Identification of a protein that purifies with the scrapie prion. Science. 218:1982;1309-1311.
-
(1982)
Science
, vol.218
, pp. 1309-1311
-
-
Bolton, D.C.1
McKinley, M.P.2
Prusiner, S.B.3
-
3
-
-
0028143841
-
Mouse cortical cells lacking cellular PrP survive in culture with a neurotoxic PrP fragment
-
Brown D.R., Herms J., Kretzschmar H.A. Mouse cortical cells lacking cellular PrP survive in culture with a neurotoxic PrP fragment. Neuroreport. 5:1994;2057-2060.
-
(1994)
Neuroreport
, vol.5
, pp. 2057-2060
-
-
Brown, D.R.1
Herms, J.2
Kretzschmar, H.A.3
-
4
-
-
0026600865
-
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
-
Bueler H., Fischer M., Lang Y., Bluethmann H., Lipp H., DeArmond S.J., Prusiner S.B., Aguet M., Weissmann C. Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature. 356:1992;577-582.
-
(1992)
Nature
, vol.356
, pp. 577-582
-
-
Bueler, H.1
Fischer, M.2
Lang, Y.3
Bluethmann, H.4
Lipp, H.5
DeArmond, S.J.6
Prusiner, S.B.7
Aguet, M.8
Weissmann, C.9
-
5
-
-
0027531316
-
βPP participates in PrP-amyloid plaques of Gerstmann-Straussler-Scheinker disease, Indiana kindred
-
Bugiani O., Giaccone G., Verga L., Pollo B., Frangione B., Farlow M.R., Tagliavini F., Ghetti B. βPP participates in PrP-amyloid plaques of Gerstmann-Straussler-Scheinker disease, Indiana kindred. J. Neuropathol. Exp. Neurol. 52:1993;64-70.
-
(1993)
J. Neuropathol. Exp. Neurol.
, vol.52
, pp. 64-70
-
-
Bugiani, O.1
Giaccone, G.2
Verga, L.3
Pollo, B.4
Frangione, B.5
Farlow, M.R.6
Tagliavini, F.7
Ghetti, B.8
-
6
-
-
0028986916
-
Beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding
-
Busciglio J., Lorenzo A., Yeh J., Yankner B.A. Beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding. Neuron. 14:1995;879-888.
-
(1995)
Neuron
, vol.14
, pp. 879-888
-
-
Busciglio, J.1
Lorenzo, A.2
Yeh, J.3
Yankner, B.A.4
-
7
-
-
0032897878
-
Recombinant human amyloid precursor-like protein 2 (APLP2) expressed in the yeast Pichia pastoris can stimulate neurite outgrowth
-
Cappai R., Mok S.S., Galatis D., Tucker D.F., Henry A., Beyreuther K., Small D.H., Masters C.L. Recombinant human amyloid precursor-like protein 2 (APLP2) expressed in the yeast Pichia pastoris can stimulate neurite outgrowth. FEBS Lett. 442:1999;95-98.
-
(1999)
FEBS Lett.
, vol.442
, pp. 95-98
-
-
Cappai, R.1
Mok, S.S.2
Galatis, D.3
Tucker, D.F.4
Henry, A.5
Beyreuther, K.6
Small, D.H.7
Masters, C.L.8
-
8
-
-
0033574264
-
Familial prion protein mutation alters the secondary structure of recombinant mouse prion protein: Implications for the mechanism of prion formation
-
Cappai R., Stewart L.R., Jobling M.F., Thyer J.M., White A.R., Collins S.J., Beyreuther K., Masters C.L., Barrow C.J. Familial prion protein mutation alters the secondary structure of recombinant mouse prion protein: implications for the mechanism of prion formation. Biochemistry. 38:1999;3280-3284.
-
(1999)
Biochemistry
, vol.38
, pp. 3280-3284
-
-
Cappai, R.1
Stewart, L.R.2
Jobling, M.F.3
Thyer, J.M.4
White, A.R.5
Collins, S.J.6
Beyreuther, K.7
Masters, C.L.8
Barrow, C.J.9
-
9
-
-
0000875128
-
Aβ induces increased expression and processing of amyloid precursor protein in cortical neurons
-
Cribbs D.H., Davis-Salinas J., Cotman C.W., Van Nostrand W.E. Aβ induces increased expression and processing of amyloid precursor protein in cortical neurons. Alzheimer Res. 1:1995;197-200.
-
(1995)
Alzheimer Res.
, vol.1
, pp. 197-200
-
-
Cribbs, D.H.1
Davis-Salinas, J.2
Cotman, C.W.3
Van Nostrand, W.E.4
-
10
-
-
0034705076
-
Fibril formation and neurotoxicity by a herpes simplex virus glycoprotein B fragment with homology to the Alzheimer's Aβ peptide
-
Cribbs D.H., Azizeh B.Y., Cotman C.W., LaFerla F.M. Fibril formation and neurotoxicity by a herpes simplex virus glycoprotein B fragment with homology to the Alzheimer's Aβ peptide. Biochemistry. 39:2000;5988-5994.
-
(2000)
Biochemistry
, vol.39
, pp. 5988-5994
-
-
Cribbs, D.H.1
Azizeh, B.Y.2
Cotman, C.W.3
LaFerla, F.M.4
-
11
-
-
0030297178
-
Copper, iron, and zinc imbalances in severely degenerated brain regions in Alzheimer's disease: Possible relation to oxidative stress
-
Deibel M.A., Ehmann W.D., Markesbery W.R. Copper, iron, and zinc imbalances in severely degenerated brain regions in Alzheimer's disease: possible relation to oxidative stress. J. Neurol. Sci. 143:1996;137-142.
-
(1996)
J. Neurol. Sci.
, vol.143
, pp. 137-142
-
-
Deibel, M.A.1
Ehmann, W.D.2
Markesbery, W.R.3
-
12
-
-
0030879686
-
Selective phosphorylation of adult tau isoforms in mature hippocampal neurons exposed to fibrillar A-beta
-
Ferreira A., Lu Q., Orecchio L., Kosik K.S. Selective phosphorylation of adult tau isoforms in mature hippocampal neurons exposed to fibrillar A-beta. Mol. Cell. Neurosci. 9:1997;220-234.
-
(1997)
Mol. Cell. Neurosci.
, vol.9
, pp. 220-234
-
-
Ferreira, A.1
Lu, Q.2
Orecchio, L.3
Kosik, K.S.4
-
13
-
-
0027483615
-
Neurotoxicity of a prion protein fragment
-
Forloni G., Angeretti N., Chiesa R., Monzani E., Salmona M., Bugiani O., Tagliavini F. Neurotoxicity of a prion protein fragment. Nature. 362:1993;543-546.
-
(1993)
Nature
, vol.362
, pp. 543-546
-
-
Forloni, G.1
Angeretti, N.2
Chiesa, R.3
Monzani, E.4
Salmona, M.5
Bugiani, O.6
Tagliavini, F.7
-
14
-
-
0020410055
-
Heterogeneity of microtubule-associated proteins and brain development
-
Francon J., Lennon A.M., Fellous A., Mareck A., Pierre M., Nunez J. Heterogeneity of microtubule-associated proteins and brain development. Eur. J. Biochem. 129:1982;465-471.
-
(1982)
Eur. J. Biochem.
, vol.129
, pp. 465-471
-
-
Francon, J.1
Lennon, A.M.2
Fellous, A.3
Mareck, A.4
Pierre, M.5
Nunez, J.6
-
15
-
-
0021207461
-
Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein
-
Glenner G.G., Wong C.W. Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril protein. Biochem. Biophys. Res. Commun. 122:1984;1131-1135.
-
(1984)
Biochem. Biophys. Res. Commun.
, vol.122
, pp. 1131-1135
-
-
Glenner, G.G.1
Wong, C.W.2
-
16
-
-
0345654322
-
Neuronal apoptosis in Creutzfeldt-Jakob disease
-
Gray F., Chretien F., Adle-Biassette H., Dorandeu A., Ereau T., Delisle M.-B., Kopp N., Ironside J.W., Vital C. Neuronal apoptosis in Creutzfeldt-Jakob disease. J. Neuropathol. Exp. Neurol. 58:1999;321-328.
-
(1999)
J. Neuropathol. Exp. Neurol.
, vol.58
, pp. 321-328
-
-
Gray, F.1
Chretien, F.2
Adle-Biassette, H.3
Dorandeu, A.4
Ereau, T.5
Delisle, M.-B.6
Kopp, N.7
Ironside, J.W.8
Vital, C.9
-
17
-
-
0032517134
-
Mouse cortical neurones lacking APP show normal neurite outgrowth and survival responses in vitro
-
Harper S.J., Bilsland J.G., Shearman M.S., Zheng H., Van der Ploeg L., Sirinathsinghji D.J. Mouse cortical neurones lacking APP show normal neurite outgrowth and survival responses in vitro. Neuroreport. 9:1998;3053-3058.
-
(1998)
Neuroreport
, vol.9
, pp. 3053-3058
-
-
Harper, S.J.1
Bilsland, J.G.2
Shearman, M.S.3
Zheng, H.4
Van der Ploeg, L.5
Sirinathsinghji, D.J.6
-
18
-
-
0031724581
-
Inhibition of platelet activation by the Alzheimer's disease amyloid precursor protein
-
Henry A., Li Q.X., Galatis D., Hesse L., Multhaup G., Beyreuther K., Masters C.L., Cappai R. Inhibition of platelet activation by the Alzheimer's disease amyloid precursor protein. Br. J. Haematol. 103:1998;402-415.
-
(1998)
Br. J. Haematol.
, vol.103
, pp. 402-415
-
-
Henry, A.1
Li, Q.X.2
Galatis, D.3
Hesse, L.4
Multhaup, G.5
Beyreuther, K.6
Masters, C.L.7
Cappai, R.8
-
19
-
-
0026101636
-
Aggregation and secondary structure of synthetic amyloid beta A4 peptides of Alzheimer's disease
-
Hilbich C., Kisters-Woike B., Reed J., Masters C.L., Beyreuther K. Aggregation and secondary structure of synthetic amyloid beta A4 peptides of Alzheimer's disease. J. Mol. Biol. 218:1991;149-163.
-
(1991)
J. Mol. Biol.
, vol.218
, pp. 149-163
-
-
Hilbich, C.1
Kisters-Woike, B.2
Reed, J.3
Masters, C.L.4
Beyreuther, K.5
-
20
-
-
0033198295
-
Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1
-
Homayouni R., Rice D.S., Sheldon M., Curran T. Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1. J. Neurosci. 19:1999;7507-7515.
-
(1999)
J. Neurosci.
, vol.19
, pp. 7507-7515
-
-
Homayouni, R.1
Rice, D.S.2
Sheldon, M.3
Curran, T.4
-
21
-
-
0033601338
-
Cu(II) potentiation of Alzheimer Aβ neurotoxicity: Correlation with cell-free hydrogen peroxide production and metal reduction
-
Huang X., Atwood C.S., Cuajungco M.P., Hartshorn M.A., Tyndall J., Hanson G.R., Stokes K.C., Leopold M., Multhaup G., Goldstein L.E., Scarpa R.C., Saunders A.J., Lim J., Moir R.D., Glabe C., Bowden E.F., Masters C.L., Fairlie D.P., Tanzi R.E., Bush A.I. Cu(II) potentiation of Alzheimer Aβ neurotoxicity: correlation with cell-free hydrogen peroxide production and metal reduction. J. Biol. Chem. 274:1999;37111-37116.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37111-37116
-
-
Huang, X.1
Atwood, C.S.2
Cuajungco, M.P.3
Hartshorn, M.A.4
Tyndall, J.5
Hanson, G.R.6
Stokes, K.C.7
Leopold, M.8
Multhaup, G.9
Goldstein, L.E.10
Scarpa, R.C.11
Saunders, A.J.12
Lim, J.13
Moir, R.D.14
Glabe, C.15
Bowden, E.F.16
Masters, C.L.17
Fairlie, D.P.18
Tanzi, R.E.19
Bush, A.I.20
more..
-
22
-
-
0032820644
-
The hydrophobic core sequence modulates the neurotoxic and secondary structure properties of the prion peptide 106-126
-
Jobling M.F., Stewart L.R., White A.R., McLean C., Friedhuber A., Maher F., Beyreuther K., Masters C.L., Barrow C.J., Collins S.J., Cappai R. The hydrophobic core sequence modulates the neurotoxic and secondary structure properties of the prion peptide 106-126. J. Neurochem. 73:1999;1557-1565.
-
(1999)
J. Neurochem.
, vol.73
, pp. 1557-1565
-
-
Jobling, M.F.1
Stewart, L.R.2
White, A.R.3
McLean, C.4
Friedhuber, A.5
Maher, F.6
Beyreuther, K.7
Masters, C.L.8
Barrow, C.J.9
Collins, S.J.10
Cappai, R.11
-
23
-
-
0033636136
-
Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-1
-
Kamal A., Stokin G.B., Yang Z., Xia C.-H., Goldstein L.S.B. Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-1. Neuron. 28:2000;449-459.
-
(2000)
Neuron
, vol.28
, pp. 449-459
-
-
Kamal, A.1
Stokin, G.B.2
Yang, Z.3
Xia, C.-H.4
Goldstein, L.S.B.5
-
24
-
-
0019164525
-
The structure of plasma low density lipoproteins: Experimental facts and interpretations: A minireview
-
Kirchhausen T., Fless G., Scanu A.M. The structure of plasma low density lipoproteins: experimental facts and interpretations: a minireview. Lipids. 15:1980;464-467.
-
(1980)
Lipids
, vol.15
, pp. 464-467
-
-
Kirchhausen, T.1
Fless, G.2
Scanu, A.M.3
-
25
-
-
0030813068
-
High density lipoprotein aggregated by oxidation induces degeneration of neuronal cells
-
Kivatinitz S.C., Pelsman M.A., Alonso A.D., Bagatolli L., Quiroga S. High density lipoprotein aggregated by oxidation induces degeneration of neuronal cells. J. Neurochem. 69:1997;2102-2114.
-
(1997)
J. Neurochem.
, vol.69
, pp. 2102-2114
-
-
Kivatinitz, S.C.1
Pelsman, M.A.2
Alonso, A.D.3
Bagatolli, L.4
Quiroga, S.5
-
26
-
-
0028172886
-
Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red
-
Lorenzo A., Yankner B.A. Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red. Proc. Natl. Acad. Sci. USA. 91:1994;12243-12247.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12243-12247
-
-
Lorenzo, A.1
Yankner, B.A.2
-
27
-
-
0028303844
-
Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus
-
Lorenzo A., Razzaboni B., Weir G.C., Yankner B.A. Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus. Nature. 368:1994;756-760.
-
(1994)
Nature
, vol.368
, pp. 756-760
-
-
Lorenzo, A.1
Razzaboni, B.2
Weir, G.C.3
Yankner, B.A.4
-
28
-
-
0033944538
-
Amyloid beta interacts with the amyloid precursor protein: A potential toxic mechanism in Alzheimer's disease
-
Lorenzo A., Yuan M., Zhang Z., Paganetti P.A., Sturchler-Pierrat C., Staufenbiel M., Mautino J., Vigo F.S., Sommer B., Yankner B.A. Amyloid beta interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease. Nat. Neurosci. 3:2000;460-464.
-
(2000)
Nat. Neurosci.
, vol.3
, pp. 460-464
-
-
Lorenzo, A.1
Yuan, M.2
Zhang, Z.3
Paganetti, P.A.4
Sturchler-Pierrat, C.5
Staufenbiel, M.6
Mautino, J.7
Vigo, F.S.8
Sommer, B.9
Yankner, B.A.10
-
29
-
-
0032507975
-
Copper, iron and zinc in Alzheimer's disease senile plaques
-
Lovell M.A., Robertson J.D., Teesdale W.J., Campbell J.L., Markesbery W.R. Copper, iron and zinc in Alzheimer's disease senile plaques. J. Neurol. Sci. 158:1998;47-52.
-
(1998)
J. Neurol. Sci.
, vol.158
, pp. 47-52
-
-
Lovell, M.A.1
Robertson, J.D.2
Teesdale, W.J.3
Campbell, J.L.4
Markesbery, W.R.5
-
30
-
-
0012510759
-
Amyloid plaque core protein in Alzheimer disease and Down syndrome
-
Masters C.L., Simms G., Weinman N.A., Multhaup G., McDonald B.L., Beyreuther K. Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc. Natl. Acad. Sci. USA. 82:1985;4245-4249.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 4245-4249
-
-
Masters, C.L.1
Simms, G.2
Weinman, N.A.3
Multhaup, G.4
McDonald, B.L.5
Beyreuther, K.6
-
31
-
-
0027478347
-
Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein
-
Mattson M.P., Cheng B., Culwell A.R., Esch F.S., Lieberburg I., Rydel R.E. Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein. Neuron. 10:1993;243-254.
-
(1993)
Neuron
, vol.10
, pp. 243-254
-
-
Mattson, M.P.1
Cheng, B.2
Culwell, A.R.3
Esch, F.S.4
Lieberburg, I.5
Rydel, R.E.6
-
32
-
-
0030797336
-
4-Hydroxynonenal, a product of lipid peroxidation, inhibits dephosphorylation of the microtubule-associated protein tau
-
Mattson M.P., Fu W., Waeg G., Uchida K. 4-Hydroxynonenal, a product of lipid peroxidation, inhibits dephosphorylation of the microtubule-associated protein tau. Neuroreport. 8:1997;2275-2281.
-
(1997)
Neuroreport
, vol.8
, pp. 2275-2281
-
-
Mattson, M.P.1
Fu, W.2
Waeg, G.3
Uchida, K.4
-
33
-
-
0034737720
-
Fibrillar amyloid beta-protein mediates the pathologic accumulation of its secreted precursor in human cerebrovascular smooth muscle cells
-
Melchor J.P., Van Nostrand W.E. Fibrillar amyloid beta-protein mediates the pathologic accumulation of its secreted precursor in human cerebrovascular smooth muscle cells. J. Biol. Chem. 275:2000;9782-9791.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 9782-9791
-
-
Melchor, J.P.1
Van Nostrand, W.E.2
-
34
-
-
0026663993
-
The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth
-
Milward E., Papadopoulos R., Fuller S.J., Moir R.D., Small D., Beyreuther K., Masters C.L. The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth. Neuron. 9:1992;129-137.
-
(1992)
Neuron
, vol.9
, pp. 129-137
-
-
Milward, E.1
Papadopoulos, R.2
Fuller, S.J.3
Moir, R.D.4
Small, D.5
Beyreuther, K.6
Masters, C.L.7
-
35
-
-
0013347606
-
A novel metalloprotease in rat brain cleaves the amyloid precursor protein of Alzheimer's disease generating amyloidogenic fragments
-
Mok S.S., Evin G., Li Q.X., Smith I., Beyreuther K., Masters C.L., Small D.H. A novel metalloprotease in rat brain cleaves the amyloid precursor protein of Alzheimer's disease generating amyloidogenic fragments. Biochemistry. 36:1996;156-163.
-
(1996)
Biochemistry
, vol.36
, pp. 156-163
-
-
Mok, S.S.1
Evin, G.2
Li, Q.X.3
Smith, I.4
Beyreuther, K.5
Masters, C.L.6
Small, D.H.7
-
36
-
-
0032525329
-
Beta-A amyloid peptide (25-35) induced APP expression in cultured astrocytes
-
Moreno-Flores M.T., Salinero O., Wandosell F. Beta-A amyloid peptide (25-35) induced APP expression in cultured astrocytes. J. Neurosci. Res. 52:1998;661-671.
-
(1998)
J. Neurosci. Res.
, vol.52
, pp. 661-671
-
-
Moreno-Flores, M.T.1
Salinero, O.2
Wandosell, F.3
-
37
-
-
0029935396
-
The amyloid precursor protein of Alzheimer's disease in the reduction of copper (II) to copper (I)
-
Multhaup G., Schlicksupp A., Hesse L., Beher D., Ruppert T., Masters C.L., Beyreuther K. The amyloid precursor protein of Alzheimer's disease in the reduction of copper (II) to copper (I). Science. 271:1996;1406-1409.
-
(1996)
Science
, vol.271
, pp. 1406-1409
-
-
Multhaup, G.1
Schlicksupp, A.2
Hesse, L.3
Beher, D.4
Ruppert, T.5
Masters, C.L.6
Beyreuther, K.7
-
38
-
-
0032546577
-
Copper-binding amyloid precursor protein undergoes a site-specific fragmentation in the reduction of hydrogen peroxide
-
Multhaup G., Ruppert T., Schlicksupp A., Hesse L., Bill E., Pipkorn R., Masters C.L., Beyreuther K. Copper-binding amyloid precursor protein undergoes a site-specific fragmentation in the reduction of hydrogen peroxide. Biochemistry. 37:1998;7224-7230.
-
(1998)
Biochemistry
, vol.37
, pp. 7224-7230
-
-
Multhaup, G.1
Ruppert, T.2
Schlicksupp, A.3
Hesse, L.4
Bill, E.5
Pipkorn, R.6
Masters, C.L.7
Beyreuther, K.8
-
39
-
-
0027233992
-
Cytoprotective effect of NMDA receptor antagonists on prion protein (PrionSc)-induced toxicity in rat cortical cell cultures
-
Müller W.E.G., Ushijima H., Schroder H.C., Forrest J.M.S., Schatton W.F.H., Rytik P.G., Heffner-Lauc M. Cytoprotective effect of NMDA receptor antagonists on prion protein (PrionSc)-induced toxicity in rat cortical cell cultures. Eur. J. Pharmacol. 246:1993;261-267.
-
(1993)
Eur. J. Pharmacol.
, vol.246
, pp. 261-267
-
-
Müller, W.E.G.1
Ushijima, H.2
Schroder, H.C.3
Forrest, J.M.S.4
Schatton, W.F.H.5
Rytik, P.G.6
Heffner-Lauc, M.7
-
40
-
-
0032053984
-
Degeneration in vivo of rat hippocampal neurons by wild-type Alzheimer amyloid precursor protein overexpresed by adenovirus-mediated gene transfer
-
Nishimura I., Uetsuki T., Dani S.U., Ohsawa Y., Saito I., Okamura H., Uchiyama Y., Yoshikawa K. Degeneration in vivo of rat hippocampal neurons by wild-type Alzheimer amyloid precursor protein overexpresed by adenovirus-mediated gene transfer. J. Neurosci. 18:1998;2387-2398.
-
(1998)
J. Neurosci.
, vol.18
, pp. 2387-2398
-
-
Nishimura, I.1
Uetsuki, T.2
Dani, S.U.3
Ohsawa, Y.4
Saito, I.5
Okamura, H.6
Uchiyama, Y.7
Yoshikawa, K.8
-
41
-
-
0026353840
-
Alzheimer's amyloid precursor protein-positive degenerative neurites exist even within kuru plaques not specific to Alzheimer's disease
-
Ohgami T., Kitamoto T., Weidmann A., Beyreuther K., Tateishi J. Alzheimer's amyloid precursor protein-positive degenerative neurites exist even within kuru plaques not specific to Alzheimer's disease. Am. J. Pathol. 139:1991;1245-1250.
-
(1991)
Am. J. Pathol.
, vol.139
, pp. 1245-1250
-
-
Ohgami, T.1
Kitamoto, T.2
Weidmann, A.3
Beyreuther, K.4
Tateishi, J.5
-
42
-
-
0031437769
-
Human amyloid precursor-like protein 1 cDNA cloning, ectopic expression in COS-7 cells and identification of soluble forms in the cerebrospinal fluid
-
Paliga K., Peraus G., Kreger S., Dürrwang U., Hesse L., Multhaup G., Masters C.L., Beyreuther K., Weidemann A. Human amyloid precursor-like protein 1 cDNA cloning, ectopic expression in COS-7 cells and identification of soluble forms in the cerebrospinal fluid. Eur. J. Biochem. 250:1997;354-363.
-
(1997)
Eur. J. Biochem.
, vol.250
, pp. 354-363
-
-
Paliga, K.1
Peraus, G.2
Kreger, S.3
Dürrwang, U.4
Hesse, L.5
Multhaup, G.6
Masters, C.L.7
Beyreuther, K.8
Weidemann, A.9
-
43
-
-
0033571721
-
Amyloid precursor protein, although partially detergent-insoluble in mouse cerebral cortex, behaves as an atypical lipid raft protein
-
Parkin E.T., Turner A.J., Hooper N.M. Amyloid precursor protein, although partially detergent-insoluble in mouse cerebral cortex, behaves as an atypical lipid raft protein. Biochem. J. 344:1999;23-30.
-
(1999)
Biochem. J.
, vol.344
, pp. 23-30
-
-
Parkin, E.T.1
Turner, A.J.2
Hooper, N.M.3
-
44
-
-
0025910229
-
Molecular biology of prion diseases
-
Prusiner S.B. Molecular biology of prion diseases. Science. 252:1991;1515-1522.
-
(1991)
Science
, vol.252
, pp. 1515-1522
-
-
Prusiner, S.B.1
-
45
-
-
0027351432
-
Microglia progenitor cells: A subpopulation in cultures of mouse neopallial astroglia
-
Richardson A., Hao C., Fedoroff S. Microglia progenitor cells: a subpopulation in cultures of mouse neopallial astroglia. Glia. 7:1993;25-33.
-
(1993)
Glia
, vol.7
, pp. 25-33
-
-
Richardson, A.1
Hao, C.2
Fedoroff, S.3
-
46
-
-
0028174629
-
Beta amyloid protein deposition in the brain after severe head injury: Implications for the pathogenesis of Alzheimer's disease
-
Roberts G.W., Gentleman S.M., Lynch A., Murray L., Landon M., Graham D.I. Beta amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease. J. Neurol. Neurosurg. Psychiatr. 57:1994;419-425.
-
(1994)
J. Neurol. Neurosurg. Psychiatr.
, vol.57
, pp. 419-425
-
-
Roberts, G.W.1
Gentleman, S.M.2
Lynch, A.3
Murray, L.4
Landon, M.5
Graham, D.I.6
-
47
-
-
0032945805
-
Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein
-
Rossjohn J., Cappai R., Feil S.C., Henry A., McKinstry W.J., Galatis D., Hesse L., Multhaup G., Beyreuther K., Masters C.L., Parker M.W. Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein. Nat. Struct. Biol. 6:1999;327-331.
-
(1999)
Nat. Struct. Biol.
, vol.6
, pp. 327-331
-
-
Rossjohn, J.1
Cappai, R.2
Feil, S.C.3
Henry, A.4
McKinstry, W.J.5
Galatis, D.6
Hesse, L.7
Multhaup, G.8
Beyreuther, K.9
Masters, C.L.10
Parker, M.W.11
-
48
-
-
0024395366
-
Secreted form of amyloid β protein precursor is involved in the growth regulation of fibroblasts
-
Saitoh T., Sundsmo M., Roch J.-M., Kimura N., Cole G., Schenk D. Secreted form of amyloid β protein precursor is involved in the growth regulation of fibroblasts. Cell. 58:1989;615-622.
-
(1989)
Cell
, vol.58
, pp. 615-622
-
-
Saitoh, T.1
Sundsmo, M.2
Roch, J.-M.3
Kimura, N.4
Cole, G.5
Schenk, D.6
-
49
-
-
0013401339
-
Amyloid β-protein stimulates parallel increases in cellular levels of its precursor and amyloid precursor-like protein 2 (APLP2) in human smooth muscle cultures
-
Saporito-Irwin S.M., Thinskaran G., Ruffini L., Sisodia S.S., Van Nostrand W.E. Amyloid β-protein stimulates parallel increases in cellular levels of its precursor and amyloid precursor-like protein 2 (APLP2) in human smooth muscle cultures. Amyloid Int. J. Exp. Clin. Invest. 4:1997;54-60.
-
(1997)
Amyloid Int. J. Exp. Clin. Invest.
, vol.4
, pp. 54-60
-
-
Saporito-Irwin, S.M.1
Thinskaran, G.2
Ruffini, L.3
Sisodia, S.S.4
Van Nostrand, W.E.5
-
51
-
-
0033536163
-
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
-
Schenk D., Barbour R., Dunn W., Gordon G., Grajeda H., Guido T., Hu K., Huang J., Johnson-Wood K., Khan K., Kholodenko D., Lee M., Liao Z., Lieberburg I., Motter R., Mutter L., Soriano F., Shopp G., Vasquez N., Vandevert C., Walker S., Wogulis M., Yednock T., Games D., Seubert P. Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature. 400:1999;173-177.
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guido, T.6
Hu, K.7
Huang, J.8
Johnson-Wood, K.9
Khan, K.10
Kholodenko, D.11
Lee, M.12
Liao, Z.13
Lieberburg, I.14
Motter, R.15
Mutter, L.16
Soriano, F.17
Shopp, G.18
Vasquez, N.19
Vandevert, C.20
Walker, S.21
Wogulis, M.22
Yednock, T.23
Games, D.24
Seubert, P.25
more..
-
52
-
-
0031214504
-
Amyloid beta-protein (25-35) increases cellular APP and inhibits the secretion of APPs in human extraneuronal cells
-
Schmitt T.L., Steiner E., Trieb K., Grubeck-Loebenstein B. Amyloid beta-protein (25-35) increases cellular APP and inhibits the secretion of APPs in human extraneuronal cells. Exp. Cell Res. 234:1997;336-340.
-
(1997)
Exp. Cell Res.
, vol.234
, pp. 336-340
-
-
Schmitt, T.L.1
Steiner, E.2
Trieb, K.3
Grubeck-Loebenstein, B.4
-
53
-
-
0028267440
-
Normal and abnormal biology of the beta-amyloid precursor protein
-
Selkoe D.J. Normal and abnormal biology of the beta-amyloid precursor protein. Annu. Rev. Neurosci. 17:1994;489-517.
-
(1994)
Annu. Rev. Neurosci.
, vol.17
, pp. 489-517
-
-
Selkoe, D.J.1
-
54
-
-
0028059841
-
Expression of a ubiquitous, cross-reactive homologue of the mouse β-amyloid precursor protein (APP)
-
Slunt H.H., Thinakaran G., Von Koch C., Lo A.C.Y., Tanzi R.E., Sisodia S.S. Expression of a ubiquitous, cross-reactive homologue of the mouse β-amyloid precursor protein (APP). J. Biol. Chem. 269:1994;2637-2644.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 2637-2644
-
-
Slunt, H.H.1
Thinakaran, G.2
Von Koch, C.3
Lo, A.C.Y.4
Tanzi, R.E.5
Sisodia, S.S.6
-
55
-
-
0028213567
-
A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth
-
Small D.H., Nurcombe V., Reed G., Clarris H., Moir R., Beyreuther K., Masters C.L. A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth. J. Neurosci. 14:1994;2117-2127.
-
(1994)
J. Neurosci.
, vol.14
, pp. 2117-2127
-
-
Small, D.H.1
Nurcombe, V.2
Reed, G.3
Clarris, H.4
Moir, R.5
Beyreuther, K.6
Masters, C.L.7
-
56
-
-
0342781230
-
Phagocytosis of aggregated lipoprotein by macrophages: Low density lipoprotein receptor-dependent foam-cell formation
-
Suits A.G., Chait A., Aviram M., Heinecke J.W. Phagocytosis of aggregated lipoprotein by macrophages: low density lipoprotein receptor-dependent foam-cell formation. Proc. Natl. Acad. Sci. USA. 86:1989;2713-2717.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 2713-2717
-
-
Suits, A.G.1
Chait, A.2
Aviram, M.3
Heinecke, J.W.4
-
57
-
-
0027367506
-
Synthetic peptides homologous to prion protein residues 106-147 form amyloid-like fibrils in vitro
-
Tagliavini F., Prelli F., Verga L., Giaccone G., Sarma R., Gorevic P., Ghetti B., Passerini F., Ghibaudi E., Forloni G., Salmona M., Bugiani O., Frangione B. Synthetic peptides homologous to prion protein residues 106-147 form amyloid-like fibrils in vitro. Proc. Natl. Acad. Sci. USA. 90:1993;9678-9682.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 9678-9682
-
-
Tagliavini, F.1
Prelli, F.2
Verga, L.3
Giaccone, G.4
Sarma, R.5
Gorevic, P.6
Ghetti, B.7
Passerini, F.8
Ghibaudi, E.9
Forloni, G.10
Salmona, M.11
Bugiani, O.12
Frangione, B.13
-
58
-
-
0031695652
-
Activation of tau protein kinase I/glycogen synthase kinase-3beta by amyloid beta peptide (25-35) enhances phosphorylation of tau in hippocampal neurons
-
Takashima A., Honda T., Yasutake K., Michel G., Murayama O., Murayama M., Ishiguro K., Yamaguchi H. Activation of tau protein kinase I/glycogen synthase kinase-3beta by amyloid beta peptide (25-35) enhances phosphorylation of tau in hippocampal neurons. Neurosci. Res. 31:1998;317-323.
-
(1998)
Neurosci. Res.
, vol.31
, pp. 317-323
-
-
Takashima, A.1
Honda, T.2
Yasutake, K.3
Michel, G.4
Murayama, O.5
Murayama, M.6
Ishiguro, K.7
Yamaguchi, H.8
-
60
-
-
0031983456
-
Pathologic amyloid beta-protein cell surface fibril assembly on cultured human cerebrovascular smooth muscle cells
-
Van Nostrand W.E., Melchor J.P., Ruffini L. Pathologic amyloid beta-protein cell surface fibril assembly on cultured human cerebrovascular smooth muscle cells. J. Neurochem. 70:1998;216-223.
-
(1998)
J. Neurochem.
, vol.70
, pp. 216-223
-
-
Van Nostrand, W.E.1
Melchor, J.P.2
Ruffini, L.3
-
61
-
-
0037184059
-
Localization of a fibrillar amyloid β-protein binding domain on its precursor
-
Van Nostrand W.E., Melchor J.P., Keane D.M., Saporito-Irwin S.M., Romanov G., Davis J., Xu F. Localization of a fibrillar amyloid β-protein binding domain on its precursor. J. Biol. Chem. 277:2002;36392-36398.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 36392-36398
-
-
Van Nostrand, W.E.1
Melchor, J.P.2
Keane, D.M.3
Saporito-Irwin, S.M.4
Romanov, G.5
Davis, J.6
Xu, F.7
-
62
-
-
0028273377
-
An investigation into the proteolytic cleavage of Alzheimer amyloid precursor protein in PC-12 cells
-
Walsh D.M., Williams C.H., Kennedy H.E., Allsop D. An investigation into the proteolytic cleavage of Alzheimer amyloid precursor protein in PC-12 cells. Biochem. Soc. Trans. 22:1994;14S.
-
(1994)
Biochem. Soc. Trans.
, vol.22
-
-
Walsh, D.M.1
Williams, C.H.2
Kennedy, H.E.3
Allsop, D.4
-
63
-
-
0026442891
-
Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid β protein precursor
-
Wasco W., Bupp K., Magendantz M., Gusella J.F., Tanzi R.E., Solomon F. Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid β protein precursor. Proc. Natl. Acad. Sci. USA. 89:1992;10758-10762.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10758-10762
-
-
Wasco, W.1
Bupp, K.2
Magendantz, M.3
Gusella, J.F.4
Tanzi, R.E.5
Solomon, F.6
-
64
-
-
0032529710
-
Survival of cultured neurons from APP knockout mice against Alzheimer's amyloid Aβ toxicity and oxidative stress
-
White A.R., Zheng H., Galatis D., Maher F., Hesse L., Multhaup G., Beyreuther K., Masters C.L., Cappai R. Survival of cultured neurons from APP knockout mice against Alzheimer's amyloid Aβ toxicity and oxidative stress. J. Neurosci. 18:1998;6207-6217.
-
(1998)
J. Neurosci.
, vol.18
, pp. 6207-6217
-
-
White, A.R.1
Zheng, H.2
Galatis, D.3
Maher, F.4
Hesse, L.5
Multhaup, G.6
Beyreuther, K.7
Masters, C.L.8
Cappai, R.9
-
65
-
-
0033232709
-
The Alzheimer's disease amyloid precursor protein modulates copper-induced toxicity and oxidative stress in primary neuronal cultures
-
White A.R., Multhaup G., Maher F., Bellingham S., Camakaris J., Zheng H., Bush A.I., Beyreuther K., Masters C.L., Cappai R. The Alzheimer's disease amyloid precursor protein modulates copper-induced toxicity and oxidative stress in primary neuronal cultures. J. Neurosci. 19:1999;9170-9179.
-
(1999)
J. Neurosci.
, vol.19
, pp. 9170-9179
-
-
White, A.R.1
Multhaup, G.2
Maher, F.3
Bellingham, S.4
Camakaris, J.5
Zheng, H.6
Bush, A.I.7
Beyreuther, K.8
Masters, C.L.9
Cappai, R.10
-
66
-
-
0035093878
-
Homocysteine potentiates copper and amyloid beta peptide-mediated toxicity in primary neuronal cultures: Possible risk factors in the Alzheimer's-type neurodegenerative pathways
-
White A.R., Huang X., Jobling M.F., Barrow C.J., Beyreuther K., Masters C.L., Bush A.I., Cappai R. Homocysteine potentiates copper and amyloid beta peptide-mediated toxicity in primary neuronal cultures: possible risk factors in the Alzheimer's-type neurodegenerative pathways. J. Neurochem. 76:2001;1509-1520.
-
(2001)
J. Neurochem.
, vol.76
, pp. 1509-1520
-
-
White, A.R.1
Huang, X.2
Jobling, M.F.3
Barrow, C.J.4
Beyreuther, K.5
Masters, C.L.6
Bush, A.I.7
Cappai, R.8
-
67
-
-
0029896354
-
Mechanisms of neuronal degeneration in Alzheimer's disease
-
Yankner B.A. Mechanisms of neuronal degeneration in Alzheimer's disease. Neuron. 16:1996;921-932.
-
(1996)
Neuron
, vol.16
, pp. 921-932
-
-
Yankner, B.A.1
|