-
1
-
-
0028233494
-
Hydrogen peroxide mediates amyloid beta protein toxicity
-
Behl C., Davis J.B., Lesley R., Schubert D. Hydrogen peroxide mediates amyloid beta protein toxicity. Cell. 77:1994;817-827
-
(1994)
Cell
, vol.77
, pp. 817-827
-
-
Behl, C.1
Davis, J.B.2
Lesley, R.3
Schubert, D.4
-
2
-
-
0027518937
-
Alzheimer's disease-like dystrophic neurites characteristically associated with senile plaques are not found within other neurodegenerative diseases unless amyloid beta-protein deposition is present
-
Benzing W.C., Mufson E.J., Armstrong D.M. Alzheimer's disease-like dystrophic neurites characteristically associated with senile plaques are not found within other neurodegenerative diseases unless amyloid beta-protein deposition is present. Brain Res. 606:1993;10-18
-
(1993)
Brain Res.
, vol.606
, pp. 10-18
-
-
Benzing, W.C.1
Mufson, E.J.2
Armstrong, D.M.3
-
3
-
-
0030833055
-
Accelerated amyloid deposition in the brains of transgenic mice co-expressing mutant presenilin 1 and amyloid precursor proteins
-
Borchelt D.R., Ratovitski T., van Lare J., Lee M.K., Gonzales V., Jenkins N.A., Copeland N.G., Price D.L., Sisodia S.S. Accelerated amyloid deposition in the brains of transgenic mice co-expressing mutant presenilin 1 and amyloid precursor proteins. Neuron. 19(4):1997;939-945
-
(1997)
Neuron
, vol.19
, Issue.4
, pp. 939-945
-
-
Borchelt, D.R.1
Ratovitski, T.2
Van Lare, J.3
Lee, M.K.4
Gonzales, V.5
Jenkins, N.A.6
Copeland, N.G.7
Price, D.L.8
Sisodia, S.S.9
-
4
-
-
0037041420
-
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
-
Bucciantini M., Giannoni E., Chiti F., Baroni F., Formigli L., Zurdo J., Taddel N., Ramponi G., Dobson C., Stefani M. Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases. Nature. 416:2002;507-511
-
(2002)
Nature
, vol.416
, pp. 507-511
-
-
Bucciantini, M.1
Giannoni, E.2
Chiti, F.3
Baroni, F.4
Formigli, L.5
Zurdo, J.6
Taddel, N.7
Ramponi, G.8
Dobson, C.9
Stefani, M.10
-
5
-
-
0026756887
-
Methodological variables in the assessment of beta amyloid neurotoxicity
-
Busciglio J., Lorenzo A., Yankner B.A. Methodological variables in the assessment of beta amyloid neurotoxicity. Neurobiol. Aging. 13:1992;609-612
-
(1992)
Neurobiol. Aging
, vol.13
, pp. 609-612
-
-
Busciglio, J.1
Lorenzo, A.2
Yankner, B.A.3
-
6
-
-
0027429732
-
β-Amyloid neurotoxicity in human cortical culture is not mediated by excitotoxins
-
Busciglio J., Yeh J., Yankner B.A. β-Amyloid neurotoxicity in human cortical culture is not mediated by excitotoxins. J. Neurochem. 61:1993;1565-1568
-
(1993)
J. Neurochem.
, vol.61
, pp. 1565-1568
-
-
Busciglio, J.1
Yeh, J.2
Yankner, B.A.3
-
7
-
-
0028986916
-
Beta-Amyloid fibrils induce tau phosphorylation and loss of microtubule binding
-
Busciglio J., Lorenzo A., Yeh J., Yankner B.A. Beta-Amyloid fibrils induce tau phosphorylation and loss of microtubule binding. Neuron. 14:1995;879-888
-
(1995)
Neuron
, vol.14
, pp. 879-888
-
-
Busciglio, J.1
Lorenzo, A.2
Yeh, J.3
Yankner, B.A.4
-
8
-
-
0037186074
-
Altered metabolism of the Amyloid beta precursor protein is associated with mitochondrial dysfunction in Down's syndrome
-
Busciglio J., Pelsman A., Wong C., Pigino G., Yuan M., Mori H., Yankner Y.A. Altered metabolism of the Amyloid beta precursor protein is associated with mitochondrial dysfunction in Down's syndrome. Neuron. 33:2002;677-688
-
(2002)
Neuron
, vol.33
, pp. 677-688
-
-
Busciglio, J.1
Pelsman, A.2
Wong, C.3
Pigino, G.4
Yuan, M.5
Mori, H.6
Yankner, Y.A.7
-
9
-
-
0034282177
-
Regulation of amyloid precursor protein processing by Aβ in human glioma cells
-
Carlson C.D., Czilli D.L., Gitter B.D. Regulation of amyloid precursor protein processing by Aβ in human glioma cells. Neurobiol. Aging. 21:2000;747-775
-
(2000)
Neurobiol. Aging
, vol.21
, pp. 747-775
-
-
Carlson, C.D.1
Czilli, D.L.2
Gitter, B.D.3
-
10
-
-
0025773835
-
Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein
-
Cras P., Kawai M., Lowery D., Gonzalez-DeWhitt P., Greenberg B., Perry G. Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein. Proc. Natl. Acad. Sci. U. S. A. 88(17):1991;7552-7556
-
(1991)
Proc. Natl. Acad. Sci. U. S. A.
, vol.88
, Issue.17
, pp. 7552-7556
-
-
Cras, P.1
Kawai, M.2
Lowery, D.3
Gonzalez-Dewhitt, P.4
Greenberg, B.5
Perry, G.6
-
11
-
-
0034705076
-
Fibril formation and neurotoxicity by a Herpes simplex virus glycoprotein B fragment with homology to the Alzheimer's Aβ peptide
-
Cribbs D.H., Azizeh B.Y., Cotman C., LaFerla F.M. Fibril formation and neurotoxicity by a Herpes simplex virus glycoprotein B fragment with homology to the Alzheimer's Aβ peptide. Biochemistry. 39:2000;5988-5994
-
(2000)
Biochemistry
, vol.39
, pp. 5988-5994
-
-
Cribbs, D.H.1
Azizeh, B.Y.2
Cotman, C.3
Laferla, F.M.4
-
12
-
-
0028982272
-
Amyloid β-protein aggregation nullifies its pathologic properties in cultured cerebrovascular smooth muscle cells
-
Davis-Salinas J., Van Nostrand W.E. Amyloid β-protein aggregation nullifies its pathologic properties in cultured cerebrovascular smooth muscle cells. J. Biol. Chem. 270(36):1995;20887-20890
-
(1995)
J. Biol. Chem.
, vol.270
, Issue.36
, pp. 20887-20890
-
-
Davis-Salinas, J.1
Van Nostrand, W.E.2
-
13
-
-
0028983336
-
Amyloid β-protein induces its own production in cultured degenerating cerebrovascular smooth muscle cells
-
Davis-Salinas J., Saporito-Irwin S.M., Cotman C.W., Van Nostrand W.E. Amyloid β-protein induces its own production in cultured degenerating cerebrovascular smooth muscle cells. J. Neurochem. 65:1995;931-934
-
(1995)
J. Neurochem.
, vol.65
, pp. 931-934
-
-
Davis-Salinas, J.1
Saporito-Irwin, S.M.2
Cotman, C.W.3
Van Nostrand, W.E.4
-
14
-
-
0037205154
-
Amyloid precursor protein gene disruption attenuates degeneration of substantia nigra compacta neurons following axotomy
-
De Giorgio L.A., Shimizu Y., Chun H.S., Kim Y.S., Sugama S., Son J.H., Joh T.H., Volpe B.T. Amyloid precursor protein gene disruption attenuates degeneration of substantia nigra compacta neurons following axotomy. Brain Res. 938:2002;38-44
-
(2002)
Brain Res.
, vol.938
, pp. 38-44
-
-
De Giorgio, L.A.1
Shimizu, Y.2
Chun, H.S.3
Kim, Y.S.4
Sugama, S.5
Son, J.H.6
Joh, T.H.7
Volpe, B.T.8
-
15
-
-
0027215550
-
Intraneuronal compartments of the amyloid precursor protein
-
Ferreira A., Caceres A., Kosik K.S. Intraneuronal compartments of the amyloid precursor protein. J. Neurosci. 113(7):1993;3112-3123
-
(1993)
J. Neurosci.
, vol.113
, Issue.7
, pp. 3112-3123
-
-
Ferreira, A.1
Caceres, A.2
Kosik, K.S.3
-
16
-
-
0027483615
-
Neurotoxicity of a prion protein fragment
-
Forloni G., Angeretti N., Chiesa R., Monzani E., Salmona M., Bugiani O., Tagliavini F. Neurotoxicity of a prion protein fragment. Nature. 362(6420):1993;543-546
-
(1993)
Nature
, vol.362
, Issue.6420
, pp. 543-546
-
-
Forloni, G.1
Angeretti, N.2
Chiesa, R.3
Monzani, E.4
Salmona, M.5
Bugiani, O.6
Tagliavini, F.7
-
17
-
-
0037439642
-
Aberrant activation of focal adhesion proteins mediates fibrillar amyloid β-induced neuronal dystrophy
-
Grace E., Busciglio J. Aberrant activation of focal adhesion proteins mediates fibrillar amyloid β-induced neuronal dystrophy. J. Neurosci. 23:2003;493-502
-
(2003)
J. Neurosci.
, vol.23
, pp. 493-502
-
-
Grace, E.1
Busciglio, J.2
-
18
-
-
0037130570
-
Characterization of neuronal dystrophy induced by fibrillar amyloid β: IImplications for Alzheimer's disease
-
Grace E.A., Rabiner C.A., Busciglio J. Characterization of neuronal dystrophy induced by fibrillar amyloid β: implications for Alzheimer's disease. Neuroscience. 114:2002;265-273
-
(2002)
Neuroscience
, vol.114
, pp. 265-273
-
-
Grace, E.A.1
Rabiner, C.A.2
Busciglio, J.3
-
19
-
-
0028169905
-
Secreted forms of beta-amyloid precursor protein protect hippocampal neurons against amyloid beta-peptide-induced oxidative injury
-
Goodman Y., Mattson M.P. Secreted forms of beta-amyloid precursor protein protect hippocampal neurons against amyloid beta-peptide-induced oxidative injury. Exp. Neurol. 128:1994;1-12
-
(1994)
Exp. Neurol.
, vol.128
, pp. 1-12
-
-
Goodman, Y.1
Mattson, M.P.2
-
20
-
-
0032876784
-
Activation of caspase-3 in amyloid beta-induced apoptosis of cultured rat cortical neurons
-
Harada J., Sugimoto M. Activation of caspase-3 in amyloid beta-induced apoptosis of cultured rat cortical neurons. Brain Res. 842:1999;311-323
-
(1999)
Brain Res.
, vol.842
, pp. 311-323
-
-
Harada, J.1
Sugimoto, M.2
-
21
-
-
0033570337
-
Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons
-
Hartley D.M., Walsh D.M., Ye C.P., Diehl T., Vasquez S., Vassilev P.M., Teplow D.B., Selkoe D.J. Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons. J. Neurosci. 19(20):1999;8876-8884
-
(1999)
J. Neurosci.
, vol.19
, Issue.20
, pp. 8876-8884
-
-
Hartley, D.M.1
Walsh, D.M.2
Ye, C.P.3
Diehl, T.4
Vasquez, S.5
Vassilev, P.M.6
Teplow, D.B.7
Selkoe, D.J.8
-
22
-
-
0034329291
-
Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members
-
Heber S., Herms J., Gajic V., Hainfellner J., Aguzzi A., Rulicke T., von Kretzschmar H., von Koch C., Sisodia S., Tremml P., Lipp H.P., Wolfer D.P., Muller U. Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members. J. Neurosci. 20(21):2000;7951-7963
-
(2000)
J. Neurosci.
, vol.20
, Issue.21
, pp. 7951-7963
-
-
Heber, S.1
Herms, J.2
Gajic, V.3
Hainfellner, J.4
Aguzzi, A.5
Rulicke, T.6
Von Kretzschmar, H.7
Von Koch, C.8
Sisodia, S.9
Tremml, P.10
Lipp, H.P.11
Wolfer, D.P.12
Muller, U.13
-
23
-
-
0027439062
-
Amyloid-like properties of peptides flanking the epitope of amyloid precursor protein-specific monoclonal antibody 22C11
-
Hilbich C., Monning U., Grund C., Masters C.L., Beyreuther K. Amyloid-like properties of peptides flanking the epitope of amyloid precursor protein-specific monoclonal antibody 22C11. J. Biol. Chem. 268(35):1993;26571- 26577
-
(1993)
J. Biol. Chem.
, vol.268
, Issue.35
, pp. 26571-26577
-
-
Hilbich, C.1
Monning, U.2
Grund, C.3
Masters, C.L.4
Beyreuther, K.5
-
24
-
-
0029034927
-
Aggregation state and neurotoxic properties of Alzheimer beta-amyloid peptide
-
Howlett D.R., Jennings K.H., Lee D.C., Clark M.S., Brown F., Wetzel R., Wood S.J., Camilleri P., Roberts G.W. Aggregation state and neurotoxic properties of Alzheimer beta-amyloid peptide. Neurodegeneration. 4(1):1995;23-32
-
(1995)
Neurodegeneration
, vol.4
, Issue.1
, pp. 23-32
-
-
Howlett, D.R.1
Jennings, K.H.2
Lee, D.C.3
Clark, M.S.4
Brown, F.5
Wetzel, R.6
Wood, S.J.7
Camilleri, P.8
Roberts, G.W.9
-
26
-
-
0023105114
-
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
-
Kang J., Lemaire H.G., Unterbeck A., Salbaum J.M., Masters C.L., Grzeschik K.H., Multhaup G., Beyreuther K., Muller-Hill B. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature. 325:1987;733-736
-
(1987)
Nature
, vol.325
, pp. 733-736
-
-
Kang, J.1
Lemaire, H.G.2
Unterbeck, A.3
Salbaum, J.M.4
Masters, C.L.5
Grzeschik, K.H.6
Multhaup, G.7
Beyreuther, K.8
Muller-Hill, B.9
-
27
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed R., Head E., Thopson J.L., McIntire T.M., Milton S.C., Cotman C.W., Glabe C.G. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science. 300:2003;486-489
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thopson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabe, C.G.7
-
28
-
-
0037047434
-
The gamma secretase-generated carboxyl terminal domain of the amyloid precursor protein induces apoptosis via Tip60 in H4 cells
-
Kinoshita A., Whelan C.M., Berezovska O., Hyman B.T. The gamma secretase-generated carboxyl terminal domain of the amyloid precursor protein induces apoptosis via Tip60 in H4 cells. J. Biol. Chem. 277(32):2002;28530-28536
-
(2002)
J. Biol. Chem.
, vol.277
, Issue.32
, pp. 28530-28536
-
-
Kinoshita, A.1
Whelan, C.M.2
Berezovska, O.3
Hyman, B.T.4
-
29
-
-
11544279355
-
Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins
-
Lambert M.P., Barlow A.K., Chromy B.A., Edwards C., Freed R., Liosatos M., Morgan T.E., Rozovsky I., Trommer B., Viola K.L., Wals P., Zhang C., Finch C.E., Krafft G.A., Klein W.L. Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc. Natl. Acad. Sci. U. S. A. 95(11):1998;6448-6453
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, Issue.11
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
Morgan, T.E.7
Rozovsky, I.8
Trommer, B.9
Viola, K.L.10
Wals, P.11
Zhang, C.12
Finch, C.E.13
Krafft, G.A.14
Klein, W.L.15
-
30
-
-
0028982840
-
Decreased alpha-secretase-cleaved amyloid precursor protein as a diagnostic marker for Alzheimer's disease
-
Lannfelt L., Basun H., Wahlund L.O., Rowe B.A., Wagner S.L. Decreased alpha-secretase-cleaved amyloid precursor protein as a diagnostic marker for Alzheimer's disease. Nat. Med. 1(8):1995;829-832
-
(1995)
Nat. Med.
, vol.1
, Issue.8
, pp. 829-832
-
-
Lannfelt, L.1
Basun, H.2
Wahlund, L.O.3
Rowe, B.A.4
Wagner, S.L.5
-
31
-
-
0028172886
-
Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red
-
Lorenzo A., Yankner B.A. Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red. Proc. Natl. Acad. Sci. U. S. A. 91:1994;12243-12247
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 12243-12247
-
-
Lorenzo, A.1
Yankner, B.A.2
-
32
-
-
0028303844
-
Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus
-
Lorenzo A., Razzaboni B., Weir G.C., Yankner B.A. Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus. Nature. 368:1994;756-760
-
(1994)
Nature
, vol.368
, pp. 756-760
-
-
Lorenzo, A.1
Razzaboni, B.2
Weir, G.C.3
Yankner, B.A.4
-
33
-
-
0033944538
-
Amyloid beta interacts with amyloid precursor protein: A potential toxic mechanism in Alzheimer's disease
-
Lorenzo A., Yuan M., Zhang Z., Paganetti P., Sturchler-Pierrat C., Staufenbiel M., Mautino J., Sol Vigo F., Sommer B., Yankner B.A. Amyloid beta interacts with amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease. Nat. Neurosci. 3:2000;460-464
-
(2000)
Nat. Neurosci.
, vol.3
, pp. 460-464
-
-
Lorenzo, A.1
Yuan, M.2
Zhang, Z.3
Paganetti, P.4
Sturchler-Pierrat, C.5
Staufenbiel, M.6
Mautino, J.7
Sol Vigo, F.8
Sommer, B.9
Yankner, B.A.10
-
34
-
-
0142179222
-
Caspase cleavage of the amyloid precursor protein modulates amyloid β-protein toxicity
-
Lu D.C., Soriano S., Bredesen D.E., Koo E.H. Caspase cleavage of the amyloid precursor protein modulates amyloid β-protein toxicity. J. Neurochem. 87:2003;733-741
-
(2003)
J. Neurochem.
, vol.87
, pp. 733-741
-
-
Lu, D.C.1
Soriano, S.2
Bredesen, D.E.3
Koo, E.H.4
-
35
-
-
0345602771
-
Amyloid β protein toxicity mediated by the formation of Amyloid-β protein precursor complexes
-
Lu D.C., Shaked G.M., Masliah E., Bredesen D.E., Koo E.H. Amyloid β protein toxicity mediated by the formation of Amyloid-β protein precursor complexes. Ann. Neurol. 54:2003;781-789
-
(2003)
Ann. Neurol.
, vol.54
, pp. 781-789
-
-
Lu, D.C.1
Shaked, G.M.2
Masliah, E.3
Bredesen, D.E.4
Koo, E.H.5
-
36
-
-
0027297138
-
Calcium-destabilizing and neurodegenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF
-
Mattson M.P., Tomaselli K.J., Rydel R.E. Calcium-destabilizing and neurodegenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF. Brain Res. 621:1993;35-49
-
(1993)
Brain Res.
, vol.621
, pp. 35-49
-
-
Mattson, M.P.1
Tomaselli, K.J.2
Rydel, R.E.3
-
37
-
-
0027478347
-
Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of beta-amyloid precursor protein
-
Mattson M.P., Cheng B., Culwell A.R., Esch F.S., Lieberburg I., Rydel R.E. Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of beta-amyloid precursor protein. Neuron. 10:1993;243-254
-
(1993)
Neuron
, vol.10
, pp. 243-254
-
-
Mattson, M.P.1
Cheng, B.2
Culwell, A.R.3
Esch, F.S.4
Lieberburg, I.5
Rydel, R.E.6
-
38
-
-
0034737720
-
Fibrillar amyloid β-protein mediates the pathologic accumulation of its secreted precursor in human cerebrovascular smooth muscle cells
-
Melchor J.P., Van Nostrand W.E. Fibrillar amyloid β-protein mediates the pathologic accumulation of its secreted precursor in human cerebrovascular smooth muscle cells. J. Biol. Chem. 275(13):2000;9782-9791
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.13
, pp. 9782-9791
-
-
Melchor, J.P.1
Van Nostrand, W.E.2
-
39
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid beta
-
Nakagawa T., Zhu H., Morishima N., Li E., Xu J., Yankner B.A., Yuan J. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid beta. Nature. 403:2000;98-103
-
(2000)
Nature
, vol.403
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
Li, E.4
Xu, J.5
Yankner, B.A.6
Yuan, J.7
-
40
-
-
0027447656
-
Alzheimer amyloid protein precursor complexes with brain GTP-binding protein Go
-
Nishimoto I., Okamoto T., Matsuura Y., Takahashi S., Okamoto T., Maruyama Y., Ogata E. Alzheimer amyloid protein precursor complexes with brain GTP-binding protein Go. Nature. 362:1993;75-79
-
(1993)
Nature
, vol.362
, pp. 75-79
-
-
Nishimoto, I.1
Okamoto, T.2
Matsuura, Y.3
Takahashi, S.4
Okamoto, T.5
Maruyama, Y.6
Ogata, E.7
-
41
-
-
0032053984
-
Degeneration in vivo of rat hippocampal neurons by wild-type Alzheimer amyloid precursor protein overexpressed by adenovirus-mediated gene transfer
-
Nishimura I., Uetsuki T., Dani S.U., Ohsawa Y., Saito I., Okamura H., Uchiyama Y., Yoshikawa K. Degeneration in vivo of rat hippocampal neurons by wild-type Alzheimer amyloid precursor protein overexpressed by adenovirus-mediated gene transfer. J. Neurosci. 18:1998;2387-2398
-
(1998)
J. Neurosci.
, vol.18
, pp. 2387-2398
-
-
Nishimura, I.1
Uetsuki, T.2
Dani, S.U.3
Ohsawa, Y.4
Saito, I.5
Okamura, H.6
Uchiyama, Y.7
Yoshikawa, K.8
-
42
-
-
0031033403
-
Altered expression of amyloid protein precursor mRNA in the rat hippocampus following trimethyltin intoxication: An in situ hybridization study
-
O'Connell A.W., Strada O., Earley B., Leonard B.E. Altered expression of amyloid protein precursor mRNA in the rat hippocampus following trimethyltin intoxication: an in situ hybridization study. Neurochem. Int. 30(3):1997;313-320
-
(1997)
Neurochem. Int.
, vol.30
, Issue.3
, pp. 313-320
-
-
O'Connell, A.W.1
Strada, O.2
Earley, B.3
Leonard, B.E.4
-
43
-
-
0026353840
-
Alzheimer's amyloid precursor protein-positive degenerative neurites exist even within kuru plaques not specific to Alzheimer's disease
-
Ohgami T., Kitamoto T., Weidmann A., Beyreuther K., Tateishi J. Alzheimer's amyloid precursor protein-positive degenerative neurites exist even within kuru plaques not specific to Alzheimer's disease. Am. J. Pathol. 139(6):1991;1245-1250
-
(1991)
Am. J. Pathol.
, vol.139
, Issue.6
, pp. 1245-1250
-
-
Ohgami, T.1
Kitamoto, T.2
Weidmann, A.3
Beyreuther, K.4
Tateishi, J.5
-
44
-
-
0026594876
-
Alzheimer's amyloid precursor protein accumulates within axonal swellings in human brain lesions
-
Ohgami T., Kitamoto T., Tateishi J. Alzheimer's amyloid precursor protein accumulates within axonal swellings in human brain lesions. Neurosci. Lett. 136(1):1992;75-78
-
(1992)
Neurosci. Lett.
, vol.136
, Issue.1
, pp. 75-78
-
-
Ohgami, T.1
Kitamoto, T.2
Tateishi, J.3
-
45
-
-
0031880981
-
The effects of excitotoxicity on the expression of the amyloid precursor protein gene in the brain and its modulation by neuroprotective agents
-
Panegyres P.K. The effects of excitotoxicity on the expression of the amyloid precursor protein gene in the brain and its modulation by neuroprotective agents. J. Neural Transm. 105(4-5):1998;463-478
-
(1998)
J. Neural Transm.
, vol.105
, Issue.45
, pp. 463-478
-
-
Panegyres, P.K.1
-
46
-
-
0033215972
-
Cerebral amyloid induces aberrant axonal sprouting and ectopic terminal formation in amyloid precursor protein transgenic mice
-
Phinney A.L., Deller T., Stalder M., Calhoun M.E., Frotscher M., Sommer B., Staufenbiel M., Jucker M. Cerebral amyloid induces aberrant axonal sprouting and ectopic terminal formation in amyloid precursor protein transgenic mice. J. Neurosci. 19(19):1999;8552-8559
-
(1999)
J. Neurosci.
, vol.19
, Issue.19
, pp. 8552-8559
-
-
Phinney, A.L.1
Deller, T.2
Stalder, M.3
Calhoun, M.E.4
Frotscher, M.5
Sommer, B.6
Staufenbiel, M.7
Jucker, M.8
-
47
-
-
0035116513
-
Presenilin-1 mutations reduce cytoskeletal association, deregulate neurite growth, and potentiate neuronal dystrophy and tau phosphorylation
-
Pigino G., Pelsman A., Mori H., Busciglio J. Presenilin-1 mutations reduce cytoskeletal association, deregulate neurite growth, and potentiate neuronal dystrophy and tau phosphorylation. J. Neurosci. 21:2001;834-842
-
(2001)
J. Neurosci.
, vol.21
, pp. 834-842
-
-
Pigino, G.1
Pelsman, A.2
Mori, H.3
Busciglio, J.4
-
48
-
-
0025992417
-
In vitro aging of beta amyloid protein causes peptide aggregation and neurotoxicity
-
Pike C.J., Burduick D., Walancewicz A., Glabe C.G., Cotman C.W. In vitro aging of beta amyloid protein causes peptide aggregation and neurotoxicity. Brain Res. 563:1991;311-314
-
(1991)
Brain Res.
, vol.563
, pp. 311-314
-
-
Pike, C.J.1
Burduick, D.2
Walancewicz, A.3
Glabe, C.G.4
Cotman, C.W.5
-
49
-
-
0026671781
-
Beta-amyloid induces neuritic dystrophy in vitro: Similarities with Alzheimer's disease
-
Pike C.J., Cummings B.J., Cotman C.W. Beta-amyloid induces neuritic dystrophy in vitro: similarities with Alzheimer's disease. NeuroReport. 3:1992;769-772
-
(1992)
NeuroReport
, vol.3
, pp. 769-772
-
-
Pike, C.J.1
Cummings, B.J.2
Cotman, C.W.3
-
50
-
-
0034029430
-
A monoclonal antibody to amyloid precursor protein induces neuronal apatosis
-
Rohn T.T., Ivins K.J., Bahr B.A., Cotman C.W., Cribbs D.H. A monoclonal antibody to amyloid precursor protein induces neuronal apatosis. J. Neurochem. 74:2000;2331-2342
-
(2000)
J. Neurochem.
, vol.74
, pp. 2331-2342
-
-
Rohn, T.T.1
Ivins, K.J.2
Bahr, B.A.3
Cotman, C.W.4
Cribbs, D.H.5
-
51
-
-
0031717925
-
Fe65 and the protein network centered around the cytosolic domain of the Alzheimer's beta-amyloid precursor protein
-
Russo T., Faraonio R., Minopoli G., De Candia P., De Renzis S., Zambrano N. Fe65 and the protein network centered around the cytosolic domain of the Alzheimer's beta-amyloid precursor protein. FEBS Lett. 434:1998;1-7
-
(1998)
FEBS Lett.
, vol.434
, pp. 1-7
-
-
Russo, T.1
Faraonio, R.2
Minopoli, G.3
De Candia, P.4
De Renzis, S.5
Zambrano, N.6
-
52
-
-
0035954426
-
The Alzheimer amyloid precursor protein (AβPP) and Fe65, an AβPP-binding protein, regulate cell movement
-
Sabo S.L., Ikin A.F., Buxbaum J.D., Greengard P. The Alzheimer amyloid precursor protein (AβPP) and Fe65, an AβPP-binding protein, regulate cell movement. J. Cell Biol. 153:2001;1403-1414
-
(2001)
J. Cell Biol.
, vol.153
, pp. 1403-1414
-
-
Sabo, S.L.1
Ikin, A.F.2
Buxbaum, J.D.3
Greengard, P.4
-
53
-
-
0028925737
-
Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL
-
Salgia R., Li J., Lo S., Brunkhorst B., Kansas G., Sobhany E.S., Sun Y., Pisick E., Hallek M., Ernst T., et al. Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL. J. Biol. Chem. 270:1995;5039-5047
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 5039-5047
-
-
Salgia, R.1
Li, J.2
Lo, S.3
Brunkhorst, B.4
Kansas, G.5
Sobhany, E.S.6
Sun, Y.7
Pisick, E.8
Hallek, M.9
Ernst, T.10
-
54
-
-
0031214504
-
Amyloid β25-35 increases cellular APP and inhibits the secretion of APPs in human extraneuronal cells
-
Schmitt T.L., Steiner E., Trieb K., Grubeck-Loebenstein B. Amyloid β25-35 increases cellular APP and inhibits the secretion of APPs in human extraneuronal cells. Exp. Cell Res. 234:1997;336-340
-
(1997)
Exp. Cell Res.
, vol.234
, pp. 336-340
-
-
Schmitt, T.L.1
Steiner, E.2
Trieb, K.3
Grubeck-Loebenstein, B.4
-
55
-
-
0027421474
-
The expression of amyloid beta protein precursor protects nerve cells from beta-amyloid and glutamate toxicity and alters their interaction with the extracellular matrix
-
Schubert D., Behl C. The expression of amyloid beta protein precursor protects nerve cells from beta-amyloid and glutamate toxicity and alters their interaction with the extracellular matrix. Brain Res. 629(2):1993;275-282
-
(1993)
Brain Res.
, vol.629
, Issue.2
, pp. 275-282
-
-
Schubert, D.1
Behl, C.2
-
56
-
-
0035066332
-
Alzheimer's disease: Genes, proteins and therapy
-
Selkoe D. Alzheimer's disease: genes, proteins and therapy. Physiol. Rev. 81:2001;741-766
-
(2001)
Physiol. Rev.
, vol.81
, pp. 741-766
-
-
Selkoe, D.1
-
57
-
-
0027393439
-
Increased levels of the Kunitz protease inhibitor-containing beta APP mRNAs in rat brain following neurotoxic damage
-
Sola C., Garcia-Ladona F.J., Mengod G., Probst A., Frey P., Palacios J.M. Increased levels of the Kunitz protease inhibitor-containing beta APP mRNAs in rat brain following neurotoxic damage. Brain Res. Mol. Brain Res. 17(1-2):1993;41-52
-
(1993)
Brain Res. Mol. Brain Res.
, vol.17
, Issue.12
, pp. 41-52
-
-
Sola, C.1
Garcia-Ladona, F.J.2
Mengod, G.3
Probst, A.4
Frey, P.5
Palacios, J.M.6
-
58
-
-
0034525215
-
Antibody-regulated neurotoxic function of cell-surface beta amyloid precursor protein
-
Sudo H., Jiang H., Yasukawa T., Hashimoto Y., Niikura T., Kawasumi M., Matsuoka M., Murayama Y., Nishimoto I. Antibody-regulated neurotoxic function of cell-surface beta amyloid precursor protein. Mol. Cell. Neurosci. 16:2000;708-723
-
(2000)
Mol. Cell. Neurosci.
, vol.16
, pp. 708-723
-
-
Sudo, H.1
Jiang, H.2
Yasukawa, T.3
Hashimoto, Y.4
Niikura, T.5
Kawasumi, M.6
Matsuoka, M.7
Murayama, Y.8
Nishimoto, I.9
-
59
-
-
0034741266
-
Secreted Abeta does not mediate neurotoxicity by antibody-stimulated amyloid precursor protein
-
Sudo H., Hashimoto Y., Niikura T., Shao Z., Yasukawa T., Ito Y., Yamada M., Hata M., Hiraki T., Kawasumi M., Kouyama K., Nishimoto I. Secreted Abeta does not mediate neurotoxicity by antibody-stimulated amyloid precursor protein. Biochem. Biophys. Res. Commun. 282:2001;548-556
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.282
, pp. 548-556
-
-
Sudo, H.1
Hashimoto, Y.2
Niikura, T.3
Shao, Z.4
Yasukawa, T.5
Ito, Y.6
Yamada, M.7
Hata, M.8
Hiraki, T.9
Kawasumi, M.10
Kouyama, K.11
Nishimoto, I.12
-
60
-
-
0034652232
-
Caspase-2 mediates neuronal cell death induced by amyloid beta
-
Troy C.M., Rabacchi S.A., Friedman W.J., Frappier T.F., Brown K., Shelanski M.L. Caspase-2 mediates neuronal cell death induced by amyloid beta. J. Neurosci. 20:2000;1386-1392
-
(2000)
J. Neurosci.
, vol.20
, pp. 1386-1392
-
-
Troy, C.M.1
Rabacchi, S.A.2
Friedman, W.J.3
Frappier, T.F.4
Brown, K.5
Shelanski, M.L.6
-
61
-
-
0026572465
-
Decreased levels of soluble amyloid beta-protein precursor in cerebrospinal fluid of live Alzheimer disease patients
-
Van Nostrand W.E., Wagner S.L., Shankle W.R., Farrow J.S., Dick M., Rozemuller J.M., Kuipper M.A., Wolters E.C., Zimmerman J., Cotman C.W., et al. Decreased levels of soluble amyloid beta-protein precursor in cerebrospinal fluid of live Alzheimer disease patients. Proc. Natl. Acad. Sci. U. S. A. 89(7):1992;2551-2555
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.89
, Issue.7
, pp. 2551-2555
-
-
Van Nostrand, W.E.1
Wagner, S.L.2
Shankle, W.R.3
Farrow, J.S.4
Dick, M.5
Rozemuller, J.M.6
Kuipper, M.A.7
Wolters, E.C.8
Zimmerman, J.9
Cotman, C.W.10
-
62
-
-
0037184059
-
Localization of a fibrillar amyloid β-protein binding domain on its precursor
-
Van Nostrand W.E., Melchor J., Keane D., Saporito-Irwin S., Romanov G., Davis J., Xu F. Localization of a fibrillar amyloid β-protein binding domain on its precursor. J. Biol. Chem. 277(27):2002;36392-36398
-
(2002)
J. Biol. Chem.
, vol.277
, Issue.27
, pp. 36392-36398
-
-
Van Nostrand, W.E.1
Melchor, J.2
Keane, D.3
Saporito-Irwin, S.4
Romanov, G.5
Davis, J.6
Xu, F.7
-
63
-
-
0034720732
-
Fibrillar amyloid beta protein binds protease nexin2/amyloid beta-protein precursor: Stimulation of its inhibition of coagulation factor XIa
-
Wagner M.R., Keane D., Melchor J., Auspaker K., Van Nostrand W. Fibrillar amyloid beta protein binds protease nexin2/amyloid beta-protein precursor: stimulation of its inhibition of coagulation factor XIa. Biochemistry. 39:2000;7420-7427
-
(2000)
Biochemistry
, vol.39
, pp. 7420-7427
-
-
Wagner, M.R.1
Keane, D.2
Melchor, J.3
Auspaker, K.4
Van Nostrand, W.5
-
64
-
-
0037041426
-
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
-
Walsh D.M., Klyubin I., Fadeeva J.V., Cullen W.K., Anwyl R., Wolfe M.S., Rowan M.J., Selkoe D.J. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature. 416(6880):2002;535-539
-
(2002)
Nature
, vol.416
, Issue.6880
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
Rowan, M.J.7
Selkoe, D.J.8
-
65
-
-
0033232709
-
The Alzheimer's disease amyloid precursor protein modulates copper-induced toxicity and oxidative stress in primary neuronal cultures
-
White Ar., Multhaup G., Maher F., Bellingham S., Camakaris J., Zheng H., Bush A.I., Beyreuther K., Masters C.L., Cappai R. The Alzheimer's disease amyloid precursor protein modulates copper-induced toxicity and oxidative stress in primary neuronal cultures. J. Neurosci. 19:1999;9170-9179
-
(1999)
J. Neurosci.
, vol.19
, pp. 9170-9179
-
-
White, Ar.1
Multhaup, G.2
Maher, F.3
Bellingham, S.4
Camakaris, J.5
Zheng, H.6
Bush, A.I.7
Beyreuther, K.8
Masters, C.L.9
Cappai, R.10
-
66
-
-
0037459782
-
Diverse fibrillar peptides directly bind the Alzheimer's amyloid precursor protein and amyloid-like protein 2 resulting in cellular accumulation
-
White A., Maher F., Brazier M., Jobling M., Thyer J., Stewart L., Thompson A., Gibson R., Masters C., Multhaup G., Beyreuther K., Barrow C., Collins S., Cappai R. Diverse fibrillar peptides directly bind the Alzheimer's amyloid precursor protein and amyloid-like protein 2 resulting in cellular accumulation. Brain Res. 966:2003;231-244
-
(2003)
Brain Res.
, vol.966
, pp. 231-244
-
-
White, A.1
Maher, F.2
Brazier, M.3
Jobling, M.4
Thyer, J.5
Stewart, L.6
Thompson, A.7
Gibson, R.8
Masters, C.9
Multhaup, G.10
Beyreuther, K.11
Barrow, C.12
Collins, S.13
Cappai, R.14
-
67
-
-
15844386159
-
G protein-mediated neuronal DNA fragmentation induced by familial Alzheimer's disease-associated mutants of APP
-
Yamatsuji T., Matsui T., Okamoto T., Komatsuzaki K., Takeda S., Fukumoto H., Iwatsudo T., Suzuki N., Asami-Odaka A., Ireland S., Kinane T., Giambarella U., Nishimoto I. G protein-mediated neuronal DNA fragmentation induced by familial Alzheimer's disease-associated mutants of APP. Science. 272:1996;1349-1352
-
(1996)
Science
, vol.272
, pp. 1349-1352
-
-
Yamatsuji, T.1
Matsui, T.2
Okamoto, T.3
Komatsuzaki, K.4
Takeda, S.5
Fukumoto, H.6
Iwatsudo, T.7
Suzuki, N.8
Asami-Odaka, A.9
Ireland, S.10
Kinane, T.11
Giambarella, U.12
Nishimoto, I.13
-
68
-
-
0031020284
-
Cell surface amyloid beta-protein precursor colocalizes with beta 1 integrins at substrate contact sites in neural cells
-
Yamazaki T., Koo E.H., Selkoe D.J. Cell surface amyloid beta-protein precursor colocalizes with beta 1 integrins at substrate contact sites in neural cells. J. Neurosci. 17(3):1997;1004-1010
-
(1997)
J. Neurosci.
, vol.17
, Issue.3
, pp. 1004-1010
-
-
Yamazaki, T.1
Koo, E.H.2
Selkoe, D.J.3
-
69
-
-
0024990330
-
Neurotrophic and neurotoxic effects of amyloid ß protein: Reversal by tachykinin neuropeptides
-
Yankner B.A., Duffy L.K., Kirschner D.A. Neurotrophic and neurotoxic effects of amyloid ß protein: reversal by tachykinin neuropeptides. Science. 250:1990;279-282
-
(1990)
Science
, vol.250
, pp. 279-282
-
-
Yankner, B.A.1
Duffy, L.K.2
Kirschner, D.A.3
-
70
-
-
0026779680
-
Degeneration in vitro of post-mitotic neurons overexpressing the Alzheimer amyloid protein precursor
-
Yoshikawa K., Aizawa T., Hayashi Y. Degeneration in vitro of post-mitotic neurons overexpressing the Alzheimer amyloid protein precursor. Nature. 359:1992;64-67
-
(1992)
Nature
, vol.359
, pp. 64-67
-
-
Yoshikawa, K.1
Aizawa, T.2
Hayashi, Y.3
-
71
-
-
0027232517
-
Basic FGF, NGF, and IGFs protect hippocampal and cortical neurons against iron-induced degeneration
-
Zhang Y., Tatsuno T., Carney J.M., Mattson M.P. Basic FGF, NGF, and IGFs protect hippocampal and cortical neurons against iron-induced degeneration. J. Cereb. Blood Flow Metab. 13(3):1993;378-388
-
(1993)
J. Cereb. Blood Flow Metab.
, vol.13
, Issue.3
, pp. 378-388
-
-
Zhang, Y.1
Tatsuno, T.2
Carney, J.M.3
Mattson, M.P.4
-
72
-
-
0027988046
-
Focal adhesion kinase expressed by nerve cell line shows increased tyrosine phosphorylation in response to Alzheimer's a beta peptide
-
Zhang C., Lambert M.P., Bunch C., Barber K., Wade W.S., Krafft G.A., Klein W.L. Focal adhesion kinase expressed by nerve cell line shows increased tyrosine phosphorylation in response to Alzheimer's A beta peptide. J. Biol. Chem. 269:1994;25247-25250
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 25247-25250
-
-
Zhang, C.1
Lambert, M.P.2
Bunch, C.3
Barber, K.4
Wade, W.S.5
Krafft, G.A.6
Klein, W.L.7
|