The Role of G Protein Activation in the Toxicity of Amyloidogenic Aβ-(1-40), Aβ-(25-35), and Bovine Calcitonin

Journal of Biological Chemistry

Volumn 276, Issue 4, 2001, Pages 2523-2530

  Rymer, Dawn L ^b   Good, Theresa A ^a  

^a Texas AandM University   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; ENZYME INHIBITION; ENZYME KINETICS; HYDROLYSIS; PATIENT TREATMENT; TOXICITY;

ALZHEIMER DISEASES;

PROTEINS;

AMYLOID BETA PROTEIN; CALCITONIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; AMYLOID BETA PROTEIN (35 25); AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA-PROTEIN (35-25); NEUROPROTECTIVE AGENT; NEUROTOXIN; PEPTIDE FRAGMENT;

ALPHA CHAIN; ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOIDOSIS; ANIMAL CELL; ARTICLE; BETA SHEET; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS; TOXICITY; ANIMAL; CATTLE; CELL MEMBRANE; CELL STRAIN; CHEMISTRY; DRUG ANTAGONISM; ENZYME ACTIVATION; METABOLISM; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE;

ANIMALIA; BOVINAE;

AMYLOID BETA-PROTEIN; AMYLOIDOSIS; ANIMALS; CALCITONIN; CATTLE; CELL MEMBRANE; ENZYME ACTIVATION; GTP-BINDING PROTEINS; NEUROPROTECTIVE AGENTS; NEUROTOXINS; PC12 CELLS; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; RATS;

EID: 0035951774     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M005800200     Document Type: Article

References (101)

1. Kelly, J. W. (1996) Curr. Opin. Struct. Biol. 6, 11-17
2. Kelly, J. W. (1998) Curr. Opin. Struct. Biol. 8, 101-106
3. Lansbury, P. T., Jr. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 3342-3344
4. Sipe, J. D. (1992) Annu. Rev. Biochem. 61, 947-975
5. Sipe, J. D. (1994) Crit. Rev. Clin. Lab. Sci. 31, 325-354
6. Kelly, J. W. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 930-932
7. Taubes, G. (1996) Science 271, 1493-1495
8. Glenner, G. G., and Terry, W. D. (1974) Annu. Rev. Med. 25, 131-135
9. Glenner, G. G. (1980) N. Engl. J. Med. 302, 1283-1292
10. Glenner, G. G. (1980) N. Engl. J. Med. 302, 1333-1343
11. Castano, E. M., and Frangione, B. (1995) Curr. Opin. Neurol. 8, 279-285
12. Walsh, D. M., Hartley, D. M., Kusumoto, Y., Fezoui, Y., Condron, M. M., Lomakin, A., Benedek, G. B., Selkoe, D. J., and Teplow, D. B. (1999) J. Biol. Chem. 274, 25945-25952
13. Howlett, D. R., Jennings, K. H., Lee, D. C., Clark, M. S., Brown, F., Wetzel, R., Wood, S. J., Camilleri, P., and Roberts, G. W. (1995) Neurodegeneration 4, 23-32
14. Ward, R. V., Jennings, K. H., Jepras, R., Neville, W., Owen, D. E., Hawkins, J., Christie, G., Davis, J. B., George, A., Karran, E. H., and Howlett, D. R. (2000) Biochem. J. 348, 137-144
15. Seilheimer, B., Bohrmann, B., Bondolfi, L., Muller, F., Stuber, D., and Dobeli, H. (1997) J. Struct. Biol. 119, 59-71
16. Yankner, B. A., Duffy, L. K., and Kirschner, D. A. (1990) Science 250, 279-282
17. Busciglio, J., Yeh, J., and Yankner, B. A. (1993) J. Neurochem. 61, 1565-1568
18. Koh, J. Y., Yang, L. L., and Cotman, C. W. (1990) Brain Res. 533, 315-320
19. Hartley, D. M., Walsh, D. M., Ye, C. P., Diehl, T., Vasquez, S., Vassilev, P. M., Teplow, D. B., and Selkoe, D. J. (1999) J. Neurosci. 19, 8876-8884
20. Lambert, M. P., Barlow, A. K., Chromy, B. A., Edwards, C., Freed, R., Liosatos, M., Morgan, T. E., Rozovsky, I., Trommer, B., Viola, K. L., Wals, P., Zhang, C., Finch, C. E., Krafft, G. A., and Klein, W. L. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 6448-6453
21. Burgevin, M. C., Passat, M., Daniel, N., Capet, M., and Doble, A. (1994) Neuroreport 5, 2429-2432
22. Lorenzo, A., and Yankner, B. A. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 12243-12247
23. Sadler, I. I., Smith, D. W., Shearman, M. S., Ragan, C. I., Tailor, V. J., and Pollack, S. J. (1995) Neuroreport 7, 49-53
24. Tomiyama, T., Asano, S., Suwa, Y., Morita, T., Kataoka, K., Mori, H., and Endo, N. (1994) Biochem. Biophys. Res. Commun. 204, 76-83
25. Arispe, N., Pollard, H. B., and Rojas, E. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 10573-10577
26. Arispe, N., Rojas, E., and Pollard, H. B. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 567-571
27. Behl, C., Davis, J. B., Lesley, R., and Schubert, D. (1994) Cell 77, 817-827
28. Butterfield, D. A., Hensley, K., Harris, M., Mattson, M., and Carney, J. (1994) Biochem. Biophys. Res. Commun. 200, 710-715
29. Butterfield, D. A. (1997) Chem. Res. Toxicol. 10, 495-506
30. Good, T. A., Smith, D. O., and Murphy, R. M. (1996) Biophys. J. 70, 296-304
31. Hensley, K., Carney, J. M., Mattson, M. P., Aksenova, M., Harris, M., Wu, J. F., Floyd, R. A., and Butterfield, D. A. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 3270-3274
32. Mattson, M. P., Mark, R. J., Furukawa, K., and Bruce, A. J. (1997) Chem. Res. Toxicol. 10, 507-517
33. McLaurin, J., and Chakrabartty, A. (1996) J. Biol. Chem. 271, 26482-26489
34. McLaurin, J., Franklin, T., Fraser, P. E., and Chakrabartty, A. (1998) J. Biol. Chem. 273, 4506-4515
35. Pike, C. J., Balazs, R., and Cotman, C. W. (1996) J. Neurochem. 67, 1774-1777
36. Simmons, M. A., and Schneider, C. R. (1993) Neurosci. Lett. 150, 133-136
37. Berger, G., Berger, N., Guillaud, M. H., Trouillas, J., and Vauzelle, J. L. (1988) Virchows Arch. A Pathol. Anat. Histopathol. 412, 543-551
38. Butler, M., and Khan, S. (1986) Arch. Pathol. Lab. Med. 110, 647-649
39. Byard, R. W., Thorner, P. S., Chan, H. S., Griffiths, A. M., and Cutz, E. (1990) Pediatr. Pathol. 10, 581-592
40. Dammrich, J., Ormanns, W., and Schaffer, R. (1984) Histochemistry 81, 369-372
41. DeLellis, R. A., Nunnemacher, G., Bitman, W. R., Gagel, R. F., Tashjian, A. H., Jr., Blount, M., and Wolfe, H. J. (1979) Lab. Invest. 40, 140-154
42. Silver, M. M., Hearn, S. A., Lines, L. D., and Troster, M. (1988) J. Histochem. Cytochem. 36, 1031-1036
43. Sletten, K., Westermark, P., and Natvig, J. B. (1976) J. Exp. Med. 143, 993-998
44. Schubert, D., Behl, C., Lesley, R., Brack, A., Dargusch, R., Sagara, Y., and Kimura, H. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 1989-1993
45. Liu, Y., and Schubert, D. (1997) J. Neurochem. 69, 2285-2293
46. Koo, E. H., Lansbury, P. T., Jr., and Kelly, J. W. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 9989-9990
47. Gorevic, P. D., Castano, E. M., Sarma, R., and Frangione, B. (1987) Biochem. Biophys. Res. Commun. 147, 854-862
48. Shen, C. L., Fitzgerald, M. C., and Murphy, R. M. (1994) Biophys. J. 67, 1238-1246
49. Shen, C. L., and Murphy, R. M. (1995) Biophys. J. 69, 640-651
50. Whitson, J. S., Mims, M. P., Strittmatter, W. J., Yamaki, T., Morrisett, J. D., and Appel, S. H. (1994) Biochem. Biophys. Res. Commun. 199, 163-170
51. Chang, C. T., Wu, C. S., and Yang, J. T. (1978) Anal. Biochem. 91, 13-31
52. Klunk, W. E., Pettegrew, J. W., and Abraham, D. J. (1989) J. Histochem. Cytochem. 37, 1293-1297
53. Klunk, W. E., Pettegrew, J. W., and Abraham, D. J. (1989) J. Histochem. Cytochem. 37, 1273-1281
54. Seifert, R., and Schultz, G. (1987) Biochem. Biophys. Res. Commun. 146, 1296-1302
55. Smith, P. K., Krohn, R. I., Hermanson, G. T., Mallia, A. K., Gartner, F. H., Provenzano, M. D., Fujimoto, E. K., Goeke, N. M., Olson, B. J., and Klenk, D. C. (1985) Anal. Biochem. 150, 76-85
56. Cassel, D., and Selinger, Z. (1976) Biochim. Biophys. Acta 452, 538-551
57. Aktories, K., Schultz, G., and Jakobs, K. H. (1983) Naunyn-Schmiedeberg's Arch. Pharmacol. 324, 196-200
58. Brouillet, E., Trembleau, A., Galanaud, D., Volovitch, M., Bouillot, C., Valenza, C., Prochiantz, A., and Allinquant, B. (1999) J. Neurosci. 19, 1717-1727
59. Klinker, J. F., Lichtenberg-Kraag, B., Damm, H., and Rommelspacher, H. (1996) Neurosci. Lett. 213, 25-28
60. Offermanns, S., Schultz, G., and Rosenthal, W. (1989) Eur. J. Biochem. 180, 283-287
61. Lazari, M. F., Porto, C. S., Freymuller, E., Abreu, L. C., and Picarelli, Z. P. (1997) Biochem. Pharmacol. 54, 399-408
62. Dorland, R. B., Middlebrook, J. L., and Leppla, S. H. (1979) J. Biol. Chem. 254, 11337-11342
63. Trop, M., and Birk, Y. (1970) Biochem. J. 116, 19-25
64. Pollack, S. J., Sadler, I. I., Hawtin, S. R., Tailor, V. J., and Shearman, M. S. (1995) Neurosci. Lett. 184, 113-116
65. Pedersen, S. E., and Ross, E. M. (1982) Proc. Natl. Acad. Sci. U. S. A. 79, 7228-7232
66. Burch, R. M., and Axelrod, J. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 6374-6378
67. Butler, S. J., Kelly, E. C., McKenzie, F. R., Guild, S. B., Wakelam, M. J., and Milligan, G. (1988) Biochem. J. 251, 201-205
68. Eckstein, F., Cassel, D., Levkovitz, H., Lowe, M., and Selinger, Z. (1979) J. Biol. Chem. 254, 9829-9834
69. Freissmuth, M., Boehm, S., Beindl, W., Nickel, P., Ijzerman, A. P., Hohenegger, M., and Nanoff, C. (1996) Mol. Pharmacol. 49, 602-611
70. Freissmuth, M., Waldhoer, M., Bofill-Cardona, E., and Nanoff, C. (1999) Trends Pharmacol. Sci. 20, 237-245
71. Gilman, A. G. (1987) Annu. Rev. Biochem. 56, 615-649
72. Huang, R. R., Dehaven, R. N., Cheung, A. H., Diehl, R. E., Dixon, R. A., and Strader, C. D. (1990) Mol. Pharmacol. 37, 304-310
73. Silk, S. T., Clejan, S., and Witkom, K. (1989) J. Biol. Chem. 264, 21466-21469
74. Birnbaumer, L. (1990) Annu. Rev. Pharmacol. Toxicol. 30, 675-705
75. Bokoch, G. M., Katada, T., Northup, J. K., Hewlett, E. L., and Gilman, A. G. (1983) J. Biol. Chem. 258, 2072-2075
76. Bokoch, G. M., Katada, T., Northup, J. K., Ui, M., and Gilman, A. G. (1984) J. Biol. Chem. 259, 3560-3567
77. Jones, D. T., and Reed, R. R. (1987) J. Biol. Chem. 262, 14241-14249
78. Jones, D. T., Masters, S. B., Bourne, H. R., and Reed, R. R. (1990) J. Biol. Chem. 265, 2671-2676
79. Cribbs, D. H., Pike, C. J., Weinstein, S. L., Velazquez, P., and Cotman, C. W. (1997) J. Biol. Chem. 272, 7431-7436
80. Pallitto, M. M., Ghanta, J., Heinzelman, P., Kiessling, L. L., and Murphy, R. M. (1999) Biochemistry 38, 3570-3578
81. Ghanta, J., Shen, C. L., Kiessling, L. L., and Murphy, R. M. (1996) J. Biol. Chem. 271, 29525-29528
82. Soomets, U., Mahlapuu, R., Tehranian, R., Jarvet, J., Karelson, E., Zilmer, M., Iverfeldt, K., Zorko, M., Graslund, A., and Langel, U. (1999) Brain Res. 850, 179-188
83. Singh, I. N., Sorrentino, G., Sitar, D. S., and Kanfer, J. N. (1998) Brain Res. 800, 275-281
84. Schnecko, A., Witte, K., Bohl, J., Ohm, T., and Lemmer, B. (1994) Brain Res. 644, 291-296
85. Brorson, J. R., Bindokas, V. P., Iwama, T., Marcuccilli, C. J., Chisholm, J. C., and Miller, R. J. (1995) J. Neurobiol. 26, 325-338
86. Mattson, M. P., Cheng, B., Davis, D., Bryant, K., Lieberburg, I., and Rydel, R. E. (1992) J. Neurosci. 12, 376-389
87. Davidson, R. M., Shajenko, L., and Donta, T. S. (1994) Brain Res. 643, 324-327
88. Li, W. Y., Czilli, D. L., and Simmons, L. K. (1995) Brain Res. 682, 207-211
89. Birnbaumer, L., Yatani, A., VanDongen, A. M., Graf, R., Codina, J., Okabe, K., Mattera, R., and Brown, A. M. (1990) Soc. Gen. Physiol. Ser. 45, 169-183
90. Brown, A. M., Yatani, A., Codina, J., and Birnbaumer, L. (1990) Prog. Clin. Biol. Res. 334, 303-312
91. Hescheler, J., Rosenthal, W., Trautwein, W., and Schultz, G. (1987) Nature 325, 445-447
92. Spiegel, A. M., Shenker, A., and Weinstein, L. S. (1992) Endocr. Rev. 13, 536-565
93. Schultz, G., Rosenthal, W., Hescheler, J., and Trautwein, W. (1990) Annu. Rev. Physiol. 52, 275-292
94. Birnbaumer, L., Abramowitz, J., and Brown, A. M. (1990) Biochim. Biophys. Acta 1031, 163-224
95. Brown, A. M., and Birnbaumer, L. (1990) Annu. Rev. Physiol. 52, 197-213
96. Simon, M. I., Strathmann, M. P., and Gautam, N. (1991) Science 252, 802-808
97. Higashijima, T., Uzu, S., Nakajima, T., and Ross, E. M. (1988) J. Biol. Chem. 263, 6491-6494
98. Gudi, S. R., Clark, C. B., and Frangos, J. A. (1996) Circ. Res. 79, 834-839
99. Berthiaume, F., and Frangos, J. A. (1994) Biochim. Biophys. Acta 1191, 209-218
100. Choo-Smith, L. P., Garzon-Rodriguez, W., Glabe, C. G., and Surewicz, W. K. (1997) J. Biol. Chem. 272, 22987-22990
101. Choo-Smith, L. P., and Surewicz, W. K. (1997) FEBS Lett. 402, 95-98