Dietary deficiency increases presenilin expression, gamma-secretase activity, and Abeta levels: Potentiation by ApoE genotype and alleviation by S-adenosyl methionine

Journal of Neurochemistry

Volumn 110, Issue 3, 2009, Pages 831-836

  Chan, Amy ^a   Tchantchou, Flaubert ^a   Rogers, Eugene J ^a   Shea, Thomas B ^a  

^a UNIVERSITY OF MASSACHUSETTS LOWELL   (United States)

Author keywords

Abeta; Alzheimer's disease; Apolipoprotein E; Folate; Gamma secretase; Presenilin; S adenosylmethionine

Indexed keywords

ALPHA TOCOPHEROL; AMYLOID BETA PROTEIN; APOLIPOPROTEIN E2; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; FOLIC ACID; GAMMA SECRETASE; IRON; PRESENILIN 1; S ADENOSYLMETHIONINE;

ALPHA TOCOPHEROL DEFICIENCY; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENZYME ACTIVITY; FOLIC ACID DEFICIENCY; GENOTYPE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RISK FACTOR;

ALLELES; AMYLOID BETA-PROTEIN; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; APOLIPOPROTEINS E; ENZYME ACTIVATION; FOLIC ACID DEFICIENCY; GENE EXPRESSION REGULATION; GENOTYPE; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PRESENILIN-1; S-ADENOSYLMETHIONINE; VITAMIN E DEFICIENCY;

MURINAE; MUS;

EID: 67650472722     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06177.x     Document Type: Article

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