Hyperhomocysteinemia increases β-amyloid by enhancing expression of γ-secretase and phosphorylation of amyloid precursor protein in rat brain

American Journal of Pathology

Volumn 174, Issue 4, 2009, Pages 1481-1491

  Zhang, Chang E ^a   Wei, Wei ^a   Liu, Ying Hua ^a   Peng, Jun Hua ^a   Tian, Qing ^a   Liu, Gong Ping ^a   Zhang, Yao ^a   Wang, Jian Zhi ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; CYANOCOBALAMIN; CYCLIN DEPENDENT KINASE 5; FOLIC ACID; GAMMA SECRETASE; HOMOCYSTEINE; MESSENGER RNA; PRESENILIN 1; PRESENILIN 2; PROTEIN P25; STRESS ACTIVATED PROTEIN KINASE; THREONINE; SECRETASE; VITAMIN B COMPLEX;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HYPERHOMOCYSTEINEMIA; MALE; MEMORY DISORDER; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; RAT; SPATIAL MEMORY; VITAMIN SUPPLEMENTATION; ANIMAL; BIOSYNTHESIS; BRAIN; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BLOTTING, WESTERN; BRAIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FOLIC ACID; GENE EXPRESSION; HYPERHOMOCYSTEINEMIA; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MEMORY DISORDERS; PHOSPHORYLATION; PRESENILIN-1; PRESENILIN-2; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; VITAMIN B 12; VITAMIN B COMPLEX;

EID: 65349162724     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2009.081036     Document Type: Article

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