-
1
-
-
67649404131
-
Blood monocytes: development, heterogeneity, and relationship with dendritic cells
-
Auffray C., et al. Blood monocytes: development, heterogeneity, and relationship with dendritic cells. Annu. Rev. Immunol. 27 (2009) 669-692
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 669-692
-
-
Auffray, C.1
-
2
-
-
22644444814
-
MacrophAging: a cellular and molecular review
-
Sebastian C., et al. MacrophAging: a cellular and molecular review. Immunobiology 210 (2005) 121-126
-
(2005)
Immunobiology
, vol.210
, pp. 121-126
-
-
Sebastian, C.1
-
3
-
-
0028198809
-
Influence of aging on some specific and nonspecific mechanisms of the host defense system in 146 healthy subjects
-
Fietta A., et al. Influence of aging on some specific and nonspecific mechanisms of the host defense system in 146 healthy subjects. Gerontology 40 (1994) 237-245
-
(1994)
Gerontology
, vol.40
, pp. 237-245
-
-
Fietta, A.1
-
4
-
-
0034663420
-
Age-related changes of human bone marrow: a histometric estimation of proliferative cells, apoptotic cells, T cells. B cells and macrophages
-
Ogawa T., et al. Age-related changes of human bone marrow: a histometric estimation of proliferative cells, apoptotic cells, T cells. B cells and macrophages. Mech. Ageing Dev. 117 (2000) 57-68
-
(2000)
Mech. Ageing Dev.
, vol.117
, pp. 57-68
-
-
Ogawa, T.1
-
6
-
-
0028597408
-
Cytokine production and aging: overproduction of IL-8 in elderly males in response to lipopolysaccharide
-
Clark J.A., and Peterson T.C. Cytokine production and aging: overproduction of IL-8 in elderly males in response to lipopolysaccharide. Mech. Ageing Dev. 77 (1994) 127-139
-
(1994)
Mech. Ageing Dev.
, vol.77
, pp. 127-139
-
-
Clark, J.A.1
Peterson, T.C.2
-
7
-
-
0031803322
-
Signal transduction in LPS-activated aged and young monocytes
-
Delpedro A.D., et al. Signal transduction in LPS-activated aged and young monocytes. J. Interferon Cytokine Res. 18 (1998) 429-437
-
(1998)
J. Interferon Cytokine Res.
, vol.18
, pp. 429-437
-
-
Delpedro, A.D.1
-
8
-
-
0037011794
-
RANTES and MIP-1alpha production by T lymphocytes, monocytes and NK cells from nonagenarian subjects
-
Mariani E., et al. RANTES and MIP-1alpha production by T lymphocytes, monocytes and NK cells from nonagenarian subjects. Exp. Gerontol. 37 (2002) 219-226
-
(2002)
Exp. Gerontol.
, vol.37
, pp. 219-226
-
-
Mariani, E.1
-
9
-
-
0029737506
-
Lower serum concentrations of cytokines in elderly patients with pneumonia and the impaired production of cytokines by peripheral blood monocytes in the elderly
-
Gon Y., et al. Lower serum concentrations of cytokines in elderly patients with pneumonia and the impaired production of cytokines by peripheral blood monocytes in the elderly. Clin. Exp. Immunol. 106 (1996) 120-126
-
(1996)
Clin. Exp. Immunol.
, vol.106
, pp. 120-126
-
-
Gon, Y.1
-
10
-
-
34548279776
-
Toll-like receptors in older adults
-
van Duin D., and Shaw A.C. Toll-like receptors in older adults. J. Am. Geriatr. Soc. 55 (2007) 1438-1444
-
(2007)
J. Am. Geriatr. Soc.
, vol.55
, pp. 1438-1444
-
-
van Duin, D.1
Shaw, A.C.2
-
11
-
-
0021739814
-
Admission criteria for immunogerontological studies in man: the SENIEUR protocol
-
Ligthart G.J., et al. Admission criteria for immunogerontological studies in man: the SENIEUR protocol. Mech. Ageing Dev. 28 (1984) 47-55
-
(1984)
Mech. Ageing Dev.
, vol.28
, pp. 47-55
-
-
Ligthart, G.J.1
-
12
-
-
33846208784
-
Age-associated defect in human TLR-1/2 function
-
van Duin D., et al. Age-associated defect in human TLR-1/2 function. J. Immunol. 178 (2007) 970-975
-
(2007)
J. Immunol.
, vol.178
, pp. 970-975
-
-
van Duin, D.1
-
13
-
-
34249107969
-
Prevaccine determination of the expression of costimulatory b7 molecules in activated monocytes predicts influenza vaccine responses in young and older adults
-
van Duin D., et al. Prevaccine determination of the expression of costimulatory b7 molecules in activated monocytes predicts influenza vaccine responses in young and older adults. J. Infect. Dis. 195 (2007) 1590-1597
-
(2007)
J. Infect. Dis.
, vol.195
, pp. 1590-1597
-
-
van Duin, D.1
-
14
-
-
47749112908
-
Dysregulation of TLR3 impairs the innate immune response to West Nile virus in the elderly
-
Kong K.F., et al. Dysregulation of TLR3 impairs the innate immune response to West Nile virus in the elderly. J. Virol. 82 (2008) 7613-7623
-
(2008)
J. Virol.
, vol.82
, pp. 7613-7623
-
-
Kong, K.F.1
-
15
-
-
5444225275
-
Impaired innate immunity predicts frailty in old age. The Leiden 85-plus study
-
van den Biggelaar A.H.J., et al. Impaired innate immunity predicts frailty in old age. The Leiden 85-plus study. Exp. Gerontol. 39 (2004) 1407-1414
-
(2004)
Exp. Gerontol.
, vol.39
, pp. 1407-1414
-
-
van den Biggelaar, A.H.J.1
-
16
-
-
54249124166
-
Aging, microglial cell priming, and the discordant central inflammatory response to signals from the peripheral immune system
-
Dilger R.N., and Johnson R.W. Aging, microglial cell priming, and the discordant central inflammatory response to signals from the peripheral immune system. J. Leukoc. Biol. 84 (2008) 932-939
-
(2008)
J. Leukoc. Biol.
, vol.84
, pp. 932-939
-
-
Dilger, R.N.1
Johnson, R.W.2
-
17
-
-
34447321028
-
Ageing and Toll-like receptor expression by innate immune cells in chronic human schistosomiasis
-
Comin F., et al. Ageing and Toll-like receptor expression by innate immune cells in chronic human schistosomiasis. Clin. Exp. Immunol. 149 (2007) 274-284
-
(2007)
Clin. Exp. Immunol.
, vol.149
, pp. 274-284
-
-
Comin, F.1
-
18
-
-
0027265827
-
Increased cytokine production in mononuclear cells of healthy elderly people
-
Fagiolo U., et al. Increased cytokine production in mononuclear cells of healthy elderly people. Eur. J. Immunol. 23 (1993) 2375-2378
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 2375-2378
-
-
Fagiolo, U.1
-
19
-
-
33846111415
-
Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans
-
Franceschi C., et al. Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans. Mech. Ageing Dev. 128 (2007) 92-105
-
(2007)
Mech. Ageing Dev.
, vol.128
, pp. 92-105
-
-
Franceschi, C.1
-
20
-
-
0034051068
-
Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty
-
Ershler W.B., and Keller E.T. Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty. Annu. Rev. Med. 51 (2000) 245-270
-
(2000)
Annu. Rev. Med.
, vol.51
, pp. 245-270
-
-
Ershler, W.B.1
Keller, E.T.2
-
21
-
-
0037396220
-
Plasma cytokine profiles in elderly humans
-
Forsey R.J., et al. Plasma cytokine profiles in elderly humans. Mech. Ageing Dev. 124 (2003) 487-493
-
(2003)
Mech. Ageing Dev.
, vol.124
, pp. 487-493
-
-
Forsey, R.J.1
-
22
-
-
0035093402
-
Serum interleukin-6, soluble interleukin-6 receptor and soluble gp130 exhibit different patterns of age- and menopause-related changes
-
Giuliani N., et al. Serum interleukin-6, soluble interleukin-6 receptor and soluble gp130 exhibit different patterns of age- and menopause-related changes. Exp. Gerontol. 36 (2001) 547-557
-
(2001)
Exp. Gerontol.
, vol.36
, pp. 547-557
-
-
Giuliani, N.1
-
23
-
-
0035140821
-
Interleukin-6 production does not increase with age
-
Beharka A.A., et al. Interleukin-6 production does not increase with age. J. Gerontol. A Biol. Sci. Med. Sci. 56 (2001) B81-B88
-
(2001)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.56
-
-
Beharka, A.A.1
-
24
-
-
0037372505
-
Chronic inflammation and the effect of IGF-I on muscle strength and power in older persons
-
Barbieri M., et al. Chronic inflammation and the effect of IGF-I on muscle strength and power in older persons. Am. J. Physiol. Endocrinol. Metab. 284 (2003) E481-E487
-
(2003)
Am. J. Physiol. Endocrinol. Metab.
, vol.284
-
-
Barbieri, M.1
-
25
-
-
0037440670
-
Coagulation and activation of inflammatory pathways in the development of functional decline and mortality in the elderly
-
Cohen H.J., et al. Coagulation and activation of inflammatory pathways in the development of functional decline and mortality in the elderly. Am. J. Med. 114 (2003) 180-187
-
(2003)
Am. J. Med.
, vol.114
, pp. 180-187
-
-
Cohen, H.J.1
-
26
-
-
0033024330
-
Serum IL-6 level and the development of disability in older persons
-
Ferrucci L., et al. Serum IL-6 level and the development of disability in older persons. J. Am. Geriatr. Soc. 47 (1999) 639-646
-
(1999)
J. Am. Geriatr. Soc.
, vol.47
, pp. 639-646
-
-
Ferrucci, L.1
-
27
-
-
34347338725
-
Inflammation and frailty in older women
-
Leng S.X., et al. Inflammation and frailty in older women. J. Am. Geriatr. Soc. 55 (2007) 864-871
-
(2007)
J. Am. Geriatr. Soc.
, vol.55
, pp. 864-871
-
-
Leng, S.X.1
-
28
-
-
2442699834
-
Frailty in older adults: evidence for a phenotype
-
Fried L.P., et al. Frailty in older adults: evidence for a phenotype. J. Gerontol. A Biol. Sci. Med. Sci. 56 (2001) M146-M156
-
(2001)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.56
-
-
Fried, L.P.1
-
29
-
-
57749202485
-
Effect of interleukin-6 polymorphisms on human longevity: a systematic review and meta-analysis
-
Di Bona D., et al. Effect of interleukin-6 polymorphisms on human longevity: a systematic review and meta-analysis. Ageing Res. Rev. 8 (2009) 36-42
-
(2009)
Ageing Res. Rev.
, vol.8
, pp. 36-42
-
-
Di Bona, D.1
-
30
-
-
27744600560
-
The immunopathogenesis of sepsis in elderly patients
-
Opal S.M., et al. The immunopathogenesis of sepsis in elderly patients. Clin. Infect. Dis. 41 Suppl 7 (2005) S504-S512
-
(2005)
Clin. Infect. Dis.
, vol.41
, Issue.SUPPL. 7
-
-
Opal, S.M.1
-
31
-
-
33745185337
-
Interleukin-6 in aging and chronic disease: a magnificent pathway
-
Maggio M., et al. Interleukin-6 in aging and chronic disease: a magnificent pathway. J. Gerontol. A Biol. Sci. Med. Sci. 61 (2006) 575-584
-
(2006)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.61
, pp. 575-584
-
-
Maggio, M.1
-
32
-
-
0037012005
-
Overproduction of monokines by leukocytes after stimulation with lipopolysaccharide in the elderly
-
Gabriel P., et al. Overproduction of monokines by leukocytes after stimulation with lipopolysaccharide in the elderly. Exp. Gerontol. 37 (2002) 235-247
-
(2002)
Exp. Gerontol.
, vol.37
, pp. 235-247
-
-
Gabriel, P.1
-
33
-
-
84891713034
-
Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor
-
Coppe J.P., et al. Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biol. 6 (2008) 2853-2868
-
(2008)
PLoS Biol.
, vol.6
, pp. 2853-2868
-
-
Coppe, J.P.1
-
34
-
-
20344384993
-
Immunosenescence and macrophage functional plasticity: dysregulation of macrophage function by age-associated microenvironmental changes
-
Stout R.D., and Suttles J. Immunosenescence and macrophage functional plasticity: dysregulation of macrophage function by age-associated microenvironmental changes. Immunol. Rev. 205 (2005) 60-71
-
(2005)
Immunol. Rev.
, vol.205
, pp. 60-71
-
-
Stout, R.D.1
Suttles, J.2
-
35
-
-
67649396851
-
-
Straub, R.H. and Mocchegiani, E. (eds) (2004) The Neuroendocrine Immune Network in Ageing (Neuroimmune Biology, 4), Elsevier
-
Straub, R.H. and Mocchegiani, E. (eds) (2004) The Neuroendocrine Immune Network in Ageing (Neuroimmune Biology, Vol. 4), Elsevier
-
-
-
-
36
-
-
48149112746
-
Leptin beyond body weight regulation-current concepts concerning its role in immune function and inflammation
-
Lago R., et al. Leptin beyond body weight regulation-current concepts concerning its role in immune function and inflammation. Cell. Immunol. 252 (2008) 139-145
-
(2008)
Cell. Immunol.
, vol.252
, pp. 139-145
-
-
Lago, R.1
-
37
-
-
0032054571
-
Endocrine regulation of murine macrophage function: effects of dehydroepiandrosterone, androstenediol, and androstenetriol
-
Padgett D.A., and Loria R.M. Endocrine regulation of murine macrophage function: effects of dehydroepiandrosterone, androstenediol, and androstenetriol. J. Neuroimmunol. 84 (1998) 61-68
-
(1998)
J. Neuroimmunol.
, vol.84
, pp. 61-68
-
-
Padgett, D.A.1
Loria, R.M.2
-
38
-
-
84975806501
-
Inflammatory networks in ageing, age-related diseases and longevity
-
Vasto S., et al. Inflammatory networks in ageing, age-related diseases and longevity. Mech. Ageing Dev. 128 (2007) 83-91
-
(2007)
Mech. Ageing Dev.
, vol.128
, pp. 83-91
-
-
Vasto, S.1
-
39
-
-
0021213410
-
Effects of aging on the in vitro response of human lymphocytes to interleukin-2
-
Yamashita N., et al. Effects of aging on the in vitro response of human lymphocytes to interleukin-2. Jpn. J. Med. 23 (1984) 211-215
-
(1984)
Jpn. J. Med.
, vol.23
, pp. 211-215
-
-
Yamashita, N.1
-
40
-
-
0026802522
-
Immunosenescence of human NK cells: effects on tumor target recognition, lethal hit and interferon sensitivity
-
Krishnaraj R. Immunosenescence of human NK cells: effects on tumor target recognition, lethal hit and interferon sensitivity. Immunol. Lett. 34 (1992) 79-84
-
(1992)
Immunol. Lett.
, vol.34
, pp. 79-84
-
-
Krishnaraj, R.1
-
41
-
-
0033026570
-
NK phenotypic markers and IL2 response in NK cells from elderly people
-
Borrego F., et al. NK phenotypic markers and IL2 response in NK cells from elderly people. Exp. Gerontol. 34 (1999) 253-265
-
(1999)
Exp. Gerontol.
, vol.34
, pp. 253-265
-
-
Borrego, F.1
-
42
-
-
0026492479
-
The impairment of natural killer function in the healthy aged is due to a postbinding deficient mechanism
-
Vitale M., et al. The impairment of natural killer function in the healthy aged is due to a postbinding deficient mechanism. Cell. Immunol. 145 (1992) 1-10
-
(1992)
Cell. Immunol.
, vol.145
, pp. 1-10
-
-
Vitale, M.1
-
43
-
-
0027381336
-
Lymphocyte subsets and natural killer cell activity in healthy old people and centenarians
-
Sansoni P., et al. Lymphocyte subsets and natural killer cell activity in healthy old people and centenarians. Blood 82 (1993) 2767-2773
-
(1993)
Blood
, vol.82
, pp. 2767-2773
-
-
Sansoni, P.1
-
44
-
-
0021259180
-
The immune status of healthy centenarians
-
Thompson J.S., et al. The immune status of healthy centenarians. J. Am. Geriatr. Soc. 32 (1984) 274-281
-
(1984)
J. Am. Geriatr. Soc.
, vol.32
, pp. 274-281
-
-
Thompson, J.S.1
-
45
-
-
0033788507
-
Functional alteration of granulocytes, NK cells, and natural killer T cells in centenarians
-
Miyaji C., et al. Functional alteration of granulocytes, NK cells, and natural killer T cells in centenarians. Hum. Immunol. 61 (2000) 908-916
-
(2000)
Hum. Immunol.
, vol.61
, pp. 908-916
-
-
Miyaji, C.1
-
46
-
-
0023225697
-
Increased number of circulating Leu 11+ (CD 16) large granular lymphocytes and decreased NK activity during human ageing
-
Facchini A., et al. Increased number of circulating Leu 11+ (CD 16) large granular lymphocytes and decreased NK activity during human ageing. Clin. Exp. Immunol. 68 (1987) 340-347
-
(1987)
Clin. Exp. Immunol.
, vol.68
, pp. 340-347
-
-
Facchini, A.1
-
47
-
-
0025113854
-
Age-associated changes in CD8+ and CD16+ cell reactivity: clonal analysis
-
Mariani E., et al. Age-associated changes in CD8+ and CD16+ cell reactivity: clonal analysis. Clin. Exp. Immunol. 81 (1990) 479-484
-
(1990)
Clin. Exp. Immunol.
, vol.81
, pp. 479-484
-
-
Mariani, E.1
-
48
-
-
0031240062
-
Natural killer cells in the late decades of human life
-
Ogata K., et al. Natural killer cells in the late decades of human life. Clin. Immunol. Immunopathol. 84 (1997) 269-275
-
(1997)
Clin. Immunol. Immunopathol.
, vol.84
, pp. 269-275
-
-
Ogata, K.1
-
49
-
-
0030607135
-
Age-associated decline in IL-2 and IL-12 induction of LAK cell activity of human PBMC samples
-
Kutza J., and Murasko D.M. Age-associated decline in IL-2 and IL-12 induction of LAK cell activity of human PBMC samples. Mech. Ageing Dev. 90 (1996) 209-222
-
(1996)
Mech. Ageing Dev.
, vol.90
, pp. 209-222
-
-
Kutza, J.1
Murasko, D.M.2
-
50
-
-
0031842690
-
Age-dependent decreases of NK cell phosphoinositide turnover during spontaneous but not Fc-mediated cytolytic activity
-
Mariani E., et al. Age-dependent decreases of NK cell phosphoinositide turnover during spontaneous but not Fc-mediated cytolytic activity. Int. Immunol. 10 (1998) 981-989
-
(1998)
Int. Immunol.
, vol.10
, pp. 981-989
-
-
Mariani, E.1
-
51
-
-
0018633191
-
Antibody-dependent cellular cytotoxicity effector cell capability among normal individuals
-
Edwards D.L., and Avis F.P. Antibody-dependent cellular cytotoxicity effector cell capability among normal individuals. J. Immunol. 123 (1979) 1887-1893
-
(1979)
J. Immunol.
, vol.123
, pp. 1887-1893
-
-
Edwards, D.L.1
Avis, F.P.2
-
52
-
-
0019592559
-
Natural killing and antibody-dependent cytotoxicity by lymphocyte subpopulations in young and aging humans
-
Fernandes G., and Gupta S. Natural killing and antibody-dependent cytotoxicity by lymphocyte subpopulations in young and aging humans. J. Clin. Immunol. 1 (1981) 141-148
-
(1981)
J. Clin. Immunol.
, vol.1
, pp. 141-148
-
-
Fernandes, G.1
Gupta, S.2
-
53
-
-
0030014593
-
Cytokine sensitivity of human NK cells during immunosenescence. 2. IL2-induced interferon gamma secretion
-
Krishnaraj R., and Bhooma T. Cytokine sensitivity of human NK cells during immunosenescence. 2. IL2-induced interferon gamma secretion. Immunol. Lett. 50 (1996) 59-63
-
(1996)
Immunol. Lett.
, vol.50
, pp. 59-63
-
-
Krishnaraj, R.1
Bhooma, T.2
-
54
-
-
0036085174
-
Chemokine production by natural killer cells from nonagenarians
-
Mariani E., et al. Chemokine production by natural killer cells from nonagenarians. Eur. J. Immunol. 32 (2002) 1524-1529
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 1524-1529
-
-
Mariani, E.1
-
55
-
-
0034916891
-
Association between natural killer cell activity and infection in immunologically normal elderly people
-
Ogata K., et al. Association between natural killer cell activity and infection in immunologically normal elderly people. Clin. Exp. Immunol. 124 (2001) 392-397
-
(2001)
Clin. Exp. Immunol.
, vol.124
, pp. 392-397
-
-
Ogata, K.1
-
56
-
-
42149193103
-
Effect of zinc supplementation on plasma IL-6 and MCP-1 production and NK cell function in healthy elderly: interactive influence of +647 MT1a and -174 IL-6 polymorphic alleles
-
Mariani E., et al. Effect of zinc supplementation on plasma IL-6 and MCP-1 production and NK cell function in healthy elderly: interactive influence of +647 MT1a and -174 IL-6 polymorphic alleles. Exp. Gerontol. 43 (2008) 462-471
-
(2008)
Exp. Gerontol.
, vol.43
, pp. 462-471
-
-
Mariani, E.1
-
57
-
-
0037398726
-
Metallothioneins/PARP-1/IL-6 interplay on natural killer cell activity in elderly: parallelism with nonagenarians and old infected humans. Effect of zinc supply
-
Mocchegiani E., et al. Metallothioneins/PARP-1/IL-6 interplay on natural killer cell activity in elderly: parallelism with nonagenarians and old infected humans. Effect of zinc supply. Mech. Ageing Dev. 124 (2003) 459-468
-
(2003)
Mech. Ageing Dev.
, vol.124
, pp. 459-468
-
-
Mocchegiani, E.1
-
58
-
-
34247842744
-
The biology of NKT cells
-
Bendelac A., et al. The biology of NKT cells. Annu. Rev. Immunol. 25 (2007) 297-336
-
(2007)
Annu. Rev. Immunol.
, vol.25
, pp. 297-336
-
-
Bendelac, A.1
-
59
-
-
0037011793
-
Valpha24+ NKT cells are decreased in elderly humans
-
DelaRosa O., et al. Valpha24+ NKT cells are decreased in elderly humans. Exp. Gerontol. 37 (2002) 213-217
-
(2002)
Exp. Gerontol.
, vol.37
, pp. 213-217
-
-
DelaRosa, O.1
-
60
-
-
34447316133
-
Aging is associated with a rapid decline in frequency, alterations in subset composition, and enhanced Th2 response in CD1d-restricted NKT cells from human peripheral blood
-
Jing Y., et al. Aging is associated with a rapid decline in frequency, alterations in subset composition, and enhanced Th2 response in CD1d-restricted NKT cells from human peripheral blood. Exp. Gerontol. 42 (2007) 719-732
-
(2007)
Exp. Gerontol.
, vol.42
, pp. 719-732
-
-
Jing, Y.1
-
61
-
-
34250314036
-
Decreased frequency and proliferative response of invariant Valpha24Vbeta11 natural killer T (iNKT) cells in healthy elderly
-
Peralbo E., et al. Decreased frequency and proliferative response of invariant Valpha24Vbeta11 natural killer T (iNKT) cells in healthy elderly. Biogerontology 7 (2006) 483-492
-
(2006)
Biogerontology
, vol.7
, pp. 483-492
-
-
Peralbo, E.1
-
62
-
-
0035915803
-
Increased expression of NK cell markers on T lymphocytes in aging and chronic activation of the immune system reflects the accumulation of effector/senescent T cells
-
Tarazona R., et al. Increased expression of NK cell markers on T lymphocytes in aging and chronic activation of the immune system reflects the accumulation of effector/senescent T cells. Mech. Ageing Dev. 121 (2000) 77-88
-
(2000)
Mech. Ageing Dev.
, vol.121
, pp. 77-88
-
-
Tarazona, R.1
-
63
-
-
34447325353
-
Invariant NKT and NKT-like lymphocytes: two different T cell subsets that are differentially affected by ageing
-
Peralbo E., et al. Invariant NKT and NKT-like lymphocytes: two different T cell subsets that are differentially affected by ageing. Exp. Gerontol. 42 (2007) 703-708
-
(2007)
Exp. Gerontol.
, vol.42
, pp. 703-708
-
-
Peralbo, E.1
-
64
-
-
40749155922
-
Induction of CD56 and TCR-independent activation of T cells with aging
-
Lemster B.H., et al. Induction of CD56 and TCR-independent activation of T cells with aging. J. Immunol. 180 (2008) 1979-1990
-
(2008)
J. Immunol.
, vol.180
, pp. 1979-1990
-
-
Lemster, B.H.1
-
65
-
-
23044510924
-
Diversity of NKR expression in aging T cells and in T cells of the aged: the new frontier into the exploration of protective immunity in the elderly
-
Abedin S., et al. Diversity of NKR expression in aging T cells and in T cells of the aged: the new frontier into the exploration of protective immunity in the elderly. Exp. Gerontol. 40 (2005) 537-548
-
(2005)
Exp. Gerontol.
, vol.40
, pp. 537-548
-
-
Abedin, S.1
-
66
-
-
50849117520
-
Epigenetic mechanisms of age-dependent KIR2DL4 expression in T cells
-
Li G., et al. Epigenetic mechanisms of age-dependent KIR2DL4 expression in T cells. J. Leukoc. Biol. 84 (2008) 824-834
-
(2008)
J. Leukoc. Biol.
, vol.84
, pp. 824-834
-
-
Li, G.1
-
67
-
-
0038217024
-
Population-based study of the epidemiology of and the risk factors for invasive Staphylococcus aureus infections
-
Laupland K.B., et al. Population-based study of the epidemiology of and the risk factors for invasive Staphylococcus aureus infections. J. Infect. Dis. 187 (2003) 1452-1459
-
(2003)
J. Infect. Dis.
, vol.187
, pp. 1452-1459
-
-
Laupland, K.B.1
-
68
-
-
0020697050
-
Infectious diseases in the elderly
-
Schneider E.L. Infectious diseases in the elderly. Ann. Intern. Med. 98 (1983) 395-400
-
(1983)
Ann. Intern. Med.
, vol.98
, pp. 395-400
-
-
Schneider, E.L.1
-
69
-
-
0030737716
-
Seeing the wood for the trees: the forgotten role of neutrophils in rheumatoid arthritis
-
Edwards S.W., and Hallett M.B. Seeing the wood for the trees: the forgotten role of neutrophils in rheumatoid arthritis. Immunol. Today 18 (1997) 320-324
-
(1997)
Immunol. Today
, vol.18
, pp. 320-324
-
-
Edwards, S.W.1
Hallett, M.B.2
-
70
-
-
21644479222
-
Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin
-
Raza K., et al. Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin. Arthritis Res. Ther. 7 (2005) R784-R795
-
(2005)
Arthritis Res. Ther.
, vol.7
-
-
Raza, K.1
-
71
-
-
39449099608
-
Age-related changes in eosinophil function in human subjects
-
Mathur S.K., et al. Age-related changes in eosinophil function in human subjects. Chest 133 (2008) 412-419
-
(2008)
Chest
, vol.133
, pp. 412-419
-
-
Mathur, S.K.1
-
72
-
-
0019914184
-
Skin reactivity, basophil degranulation and IgE levels in ageing
-
Schwarzenbach H.R., et al. Skin reactivity, basophil degranulation and IgE levels in ageing. Clin. Allergy 12 (1982) 465-473
-
(1982)
Clin. Allergy
, vol.12
, pp. 465-473
-
-
Schwarzenbach, H.R.1
-
73
-
-
0022575332
-
Human basophil releasability. I. Age-related changes in basophil releasability
-
Marone G., et al. Human basophil releasability. I. Age-related changes in basophil releasability. J. Allergy Clin. Immunol. 77 (1986) 377-383
-
(1986)
J. Allergy Clin. Immunol.
, vol.77
, pp. 377-383
-
-
Marone, G.1
-
74
-
-
39449133957
-
A mechanism for the initiation of allergen-induced T helper type 2 responses
-
Sokol C.L., et al. A mechanism for the initiation of allergen-induced T helper type 2 responses. Nat. Immunol. 9 (2008) 310-318
-
(2008)
Nat. Immunol.
, vol.9
, pp. 310-318
-
-
Sokol, C.L.1
-
75
-
-
45549087159
-
Basophils enhance immunological memory responses
-
Denzel A., et al. Basophils enhance immunological memory responses. Nat. Immunol. 9 (2008) 733-742
-
(2008)
Nat. Immunol.
, vol.9
, pp. 733-742
-
-
Denzel, A.1
-
76
-
-
54249156556
-
Aging and neutrophils: there is still much to do
-
Fortin C.F., et al. Aging and neutrophils: there is still much to do. Rejuvenation Res. 11 (2008) 873-882
-
(2008)
Rejuvenation Res.
, vol.11
, pp. 873-882
-
-
Fortin, C.F.1
-
77
-
-
0035975703
-
Neutrophil ageing and immunesenescence
-
Lord J.M., et al. Neutrophil ageing and immunesenescence. Mech. Ageing Dev. 122 (2001) 1521-1535
-
(2001)
Mech. Ageing Dev.
, vol.122
, pp. 1521-1535
-
-
Lord, J.M.1
-
78
-
-
34347361753
-
Age-related impairment of GM-CSF-induced signalling in neutrophils: role of SHP-1 and SOCS proteins
-
Tortorella C., et al. Age-related impairment of GM-CSF-induced signalling in neutrophils: role of SHP-1 and SOCS proteins. Ageing Res. Rev. 6 (2007) 81-93
-
(2007)
Ageing Res. Rev.
, vol.6
, pp. 81-93
-
-
Tortorella, C.1
-
79
-
-
0037397899
-
Neutrophil immunity of the elderly
-
Schroder A.K., and Rink L. Neutrophil immunity of the elderly. Mech. Ageing Dev. 124 (2003) 419-425
-
(2003)
Mech. Ageing Dev.
, vol.124
, pp. 419-425
-
-
Schroder, A.K.1
Rink, L.2
-
80
-
-
84919718194
-
Synergistic effects of ageing and stress on neutrophil function
-
Fulop T., et al. (Ed), Springer
-
Lord J.M., et al. Synergistic effects of ageing and stress on neutrophil function. In: Fulop T., et al. (Ed). Handbook of Immunosenescence (2009), Springer 475-498
-
(2009)
Handbook of Immunosenescence
, pp. 475-498
-
-
Lord, J.M.1
-
81
-
-
33947660464
-
GM-CSF activates the Jak/STAT pathway to rescue polymorphonuclear neutrophils from spontaneous apoptosis in young but not elderly individuals
-
Fortin C.F., et al. GM-CSF activates the Jak/STAT pathway to rescue polymorphonuclear neutrophils from spontaneous apoptosis in young but not elderly individuals. Biogerontology 8 (2007) 173-187
-
(2007)
Biogerontology
, vol.8
, pp. 173-187
-
-
Fortin, C.F.1
-
82
-
-
33745121896
-
Burying the dead: the impact of failed apoptotic cell removal (efferocytosis) on chronic inflammatory lung disease
-
Vandivier R.W., et al. Burying the dead: the impact of failed apoptotic cell removal (efferocytosis) on chronic inflammatory lung disease. Chest 129 (2006) 1673-1682
-
(2006)
Chest
, vol.129
, pp. 1673-1682
-
-
Vandivier, R.W.1
-
83
-
-
33847732694
-
Effects of aging on triggering receptor expressed on myeloid cells (TREM)-1-induced PMN functions
-
Fortin C.F., et al. Effects of aging on triggering receptor expressed on myeloid cells (TREM)-1-induced PMN functions. FEBS Lett. 581 (2007) 1173-1178
-
(2007)
FEBS Lett.
, vol.581
, pp. 1173-1178
-
-
Fortin, C.F.1
-
84
-
-
0035009177
-
Age-related changes in membrane lipid composition, fluidity and respiratory burst in rat peritoneal neutrophils
-
Alvarez E., et al. Age-related changes in membrane lipid composition, fluidity and respiratory burst in rat peritoneal neutrophils. Clin. Exp. Immunol. 124 (2001) 95-102
-
(2001)
Clin. Exp. Immunol.
, vol.124
, pp. 95-102
-
-
Alvarez, E.1
-
86
-
-
33646580485
-
Impairment of SHP-1 down-regulation in the lipid rafts of human neutrophils under GM-CSF stimulation contributes to their age-related, altered functions
-
Fortin C.F., et al. Impairment of SHP-1 down-regulation in the lipid rafts of human neutrophils under GM-CSF stimulation contributes to their age-related, altered functions. J. Leukoc. Biol. 79 (2006) 1061-1072
-
(2006)
J. Leukoc. Biol.
, vol.79
, pp. 1061-1072
-
-
Fortin, C.F.1
-
87
-
-
5644265023
-
Signal transduction and functional changes in neutrophils with aging
-
Fulop T., et al. Signal transduction and functional changes in neutrophils with aging. Aging Cell 3 (2004) 217-226
-
(2004)
Aging Cell
, vol.3
, pp. 217-226
-
-
Fulop, T.1
-
88
-
-
33845954235
-
Role of phosphoinositide 3-kinase and extracellular signal-regulated kinase pathways in granulocyte macrophage-colony-stimulating factor failure to delay fas-induced neutrophil apoptosis in elderly humans
-
Tortorella C., et al. Role of phosphoinositide 3-kinase and extracellular signal-regulated kinase pathways in granulocyte macrophage-colony-stimulating factor failure to delay fas-induced neutrophil apoptosis in elderly humans. J. Gerontol. A Biol. Sci. Med. Sci. 61 (2006) 1111-1118
-
(2006)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.61
, pp. 1111-1118
-
-
Tortorella, C.1
-
89
-
-
0030446825
-
Neutrophil migration, oxidative metabolism, and adhesion in elderly and young subjects
-
Biasi D., et al. Neutrophil migration, oxidative metabolism, and adhesion in elderly and young subjects. Inflammation 20 (1996) 673-681
-
(1996)
Inflammation
, vol.20
, pp. 673-681
-
-
Biasi, D.1
-
90
-
-
0035216133
-
Senescence in innate immune responses: reduced neutrophil phagocytic capacity and CD16 expression in elderly humans
-
Butcher S.K., et al. Senescence in innate immune responses: reduced neutrophil phagocytic capacity and CD16 expression in elderly humans. J. Leukoc. Biol. 70 (2001) 881-886
-
(2001)
J. Leukoc. Biol.
, vol.70
, pp. 881-886
-
-
Butcher, S.K.1
-
91
-
-
0033958830
-
Effect of age on human neutrophil function
-
Wenisch C., et al. Effect of age on human neutrophil function. J. Leukoc. Biol. 67 (2000) 40-45
-
(2000)
J. Leukoc. Biol.
, vol.67
, pp. 40-45
-
-
Wenisch, C.1
-
92
-
-
1342332122
-
Blood polymorphonuclear leukocyte migration as a predictive marker for infections in severe trauma: comparison with various inflammation parameters
-
Egger G., et al. Blood polymorphonuclear leukocyte migration as a predictive marker for infections in severe trauma: comparison with various inflammation parameters. Intensive Care Med. 30 (2004) 331-334
-
(2004)
Intensive Care Med.
, vol.30
, pp. 331-334
-
-
Egger, G.1
-
93
-
-
0024397502
-
Neutrophil chemotaxis, phagocytosis and parameters of reactive oxygen species in human aging: cross-sectional and longitudinal studies
-
Niwa Y., et al. Neutrophil chemotaxis, phagocytosis and parameters of reactive oxygen species in human aging: cross-sectional and longitudinal studies. Life Sci. 44 (1989) 1655-1664
-
(1989)
Life Sci.
, vol.44
, pp. 1655-1664
-
-
Niwa, Y.1
-
94
-
-
63849217133
-
The divergence and interplay between pDC and mDC in humans
-
Kadowaki N. The divergence and interplay between pDC and mDC in humans. Front. Biosci. 14 (2009) 808-817
-
(2009)
Front. Biosci.
, vol.14
, pp. 808-817
-
-
Kadowaki, N.1
-
95
-
-
33846046984
-
Peripheral blood dendritic cells and monocytes are differently regulated in the elderly
-
Della Bella S., et al. Peripheral blood dendritic cells and monocytes are differently regulated in the elderly. Clin. Immunol. 122 (2007) 220-228
-
(2007)
Clin. Immunol.
, vol.122
, pp. 220-228
-
-
Della Bella, S.1
-
96
-
-
0036436469
-
Circulating, interferon-producing plasmacytoid dendritic cells decline during human ageing
-
Shodell M., and Siegal F.P. Circulating, interferon-producing plasmacytoid dendritic cells decline during human ageing. Scand. J. Immunol. 56 (2002) 518-521
-
(2002)
Scand. J. Immunol.
, vol.56
, pp. 518-521
-
-
Shodell, M.1
Siegal, F.P.2
-
97
-
-
34249775503
-
Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathway
-
Agrawal A., et al. Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathway. J. Immunol. 178 (2007) 6912-6922
-
(2007)
J. Immunol.
, vol.178
, pp. 6912-6922
-
-
Agrawal, A.1
-
98
-
-
0029822246
-
Morphologically and functionally intact dendritic cells can be derived from the peripheral blood of aged individuals
-
Steger M.M., et al. Morphologically and functionally intact dendritic cells can be derived from the peripheral blood of aged individuals. Clin. Exp. Immunol. 105 (1996) 544-550
-
(1996)
Clin. Exp. Immunol.
, vol.105
, pp. 544-550
-
-
Steger, M.M.1
-
99
-
-
0033951305
-
Unimpaired dendritic cells can be derived from monocytes in old age and can mobilize residual function in senescent T cells
-
Lung T.L., et al. Unimpaired dendritic cells can be derived from monocytes in old age and can mobilize residual function in senescent T cells. Vaccine 18 (2000) 1606-1612
-
(2000)
Vaccine
, vol.18
, pp. 1606-1612
-
-
Lung, T.L.1
-
100
-
-
0036174828
-
Tumour necrosis factor-alpha-induced migration of human Langerhans cells: the influence of ageing
-
Bhushan M., et al. Tumour necrosis factor-alpha-induced migration of human Langerhans cells: the influence of ageing. Br. J. Dermatol. 146 (2002) 32-40
-
(2002)
Br. J. Dermatol.
, vol.146
, pp. 32-40
-
-
Bhushan, M.1
-
101
-
-
33845469025
-
Do Langerhans cells behave similarly in elderly and younger patients with chronic periodontitis?
-
Bodineau A., et al. Do Langerhans cells behave similarly in elderly and younger patients with chronic periodontitis?. Arch Oral Biol. 52 (2007) 189-194
-
(2007)
Arch Oral Biol.
, vol.52
, pp. 189-194
-
-
Bodineau, A.1
-
102
-
-
56549121816
-
Increase of gingival matured dendritic cells number in elderly patients with chronic periodontitis
-
Bodineau A., et al. Increase of gingival matured dendritic cells number in elderly patients with chronic periodontitis. Arch. Oral Biol. 54 (2009) 12-16
-
(2009)
Arch. Oral Biol.
, vol.54
, pp. 12-16
-
-
Bodineau, A.1
-
103
-
-
33750624489
-
Deterioration of the Langerhans cell network of the human gingival epithelium with aging
-
Zavala W.D., and Cavicchia J.C. Deterioration of the Langerhans cell network of the human gingival epithelium with aging. Arch. Oral Biol. 51 (2006) 1150-1155
-
(2006)
Arch. Oral Biol.
, vol.51
, pp. 1150-1155
-
-
Zavala, W.D.1
Cavicchia, J.C.2
-
104
-
-
0036668678
-
Molecular interactions of FDCs with B cells in aging
-
Szakal A.K., et al. Molecular interactions of FDCs with B cells in aging. Semin. Immunol. 14 (2002) 267-274
-
(2002)
Semin. Immunol.
, vol.14
, pp. 267-274
-
-
Szakal, A.K.1
-
105
-
-
0037397605
-
Effects of age on antibody affinity maturation
-
Dunn-Walters D.K., et al. Effects of age on antibody affinity maturation. Biochem. Soc. Trans. 31 (2003) 447-448
-
(2003)
Biochem. Soc. Trans.
, vol.31
, pp. 447-448
-
-
Dunn-Walters, D.K.1
-
106
-
-
45949103917
-
Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells
-
Frasca D., et al. Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells. J. Immunol. 180 (2008) 5283-5290
-
(2008)
J. Immunol.
, vol.180
, pp. 5283-5290
-
-
Frasca, D.1
-
107
-
-
0032524932
-
Changes in CD8 and CD4 lymphocyte subsets. T cell proliferation responses and non-survival in the very old: the Swedish longitudinal OCTO-immune study
-
Wikby A., et al. Changes in CD8 and CD4 lymphocyte subsets. T cell proliferation responses and non-survival in the very old: the Swedish longitudinal OCTO-immune study. Mech. Ageing Dev. 102 (1998) 187-198
-
(1998)
Mech. Ageing Dev.
, vol.102
, pp. 187-198
-
-
Wikby, A.1
-
108
-
-
0033106240
-
Antigen presenting cell function is enhanced in healthy elderly
-
Castle S.C., et al. Antigen presenting cell function is enhanced in healthy elderly. Mech. Ageing Dev. 107 (1999) 137-145
-
(1999)
Mech. Ageing Dev.
, vol.107
, pp. 137-145
-
-
Castle, S.C.1
-
109
-
-
0034073189
-
Surface markers and transendothelial migration of dendritic cells from elderly subjects
-
Pietschmann P., et al. Surface markers and transendothelial migration of dendritic cells from elderly subjects. Exp. Gerontol. 35 (2000) 213-224
-
(2000)
Exp. Gerontol.
, vol.35
, pp. 213-224
-
-
Pietschmann, P.1
-
110
-
-
0036499158
-
Effect of aging on cytokine production in response to respiratory syncytial virus infection
-
Looney R.J., et al. Effect of aging on cytokine production in response to respiratory syncytial virus infection. J. Infect. Dis. 185 (2002) 682-685
-
(2002)
J. Infect. Dis.
, vol.185
, pp. 682-685
-
-
Looney, R.J.1
-
111
-
-
60549108257
-
Increased reactivity of dendritic cells from aged subjects to self-antigen, the human DNA
-
Agrawal A., et al. Increased reactivity of dendritic cells from aged subjects to self-antigen, the human DNA. J. Immunol. 182 (2009) 1138-1145
-
(2009)
J. Immunol.
, vol.182
, pp. 1138-1145
-
-
Agrawal, A.1
-
112
-
-
0037629646
-
PI3K and negative regulation of TLR signaling
-
Fukao T., and Koyasu S. PI3K and negative regulation of TLR signaling. Trends Immunol. 24 (2003) 358-363
-
(2003)
Trends Immunol.
, vol.24
, pp. 358-363
-
-
Fukao, T.1
Koyasu, S.2
|