Impaired innate immunity predicts frailty in old age. The Leiden 85-plus study

Experimental Gerontology

Volumn 39, Issue 9, 2004, Pages 1407-1414

  Van Den Biggelaar, Anita H J ^a   Huizinga, Tom W J ^a   De Craen, Anton J M ^a   Gussekloo, Jacobijn ^a   Heijmans, Bastiaan T ^a   Frölich, Marijke ^a   Westendorp, Rudi G J ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Aging; Human; Immunosenescence; Innate immunity; Mortality

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CYTOKINE; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; AGED; ARTICLE; CHRONIC DISEASE; COMPARATIVE STUDY; CONFIDENCE INTERVAL; CYTOKINE PRODUCTION; FEMALE; GENETICS; HUMAN; IMMUNE RESPONSE; IMMUNITY; MALE; MORALITY; PRIORITY JOURNAL; PROMOTER REGION; RISK ASSESSMENT; SCHOOL CHILD;

AGED; AGED, 80 AND OVER; AGING; CYTOKINES; FEMALE; FOLLOW-UP STUDIES; FRAIL ELDERLY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; IMMUNITY, NATURAL; INTERLEUKIN-10; LIPOPOLYSACCHARIDES; MALE; NETHERLANDS; PROMOTER REGIONS (GENETICS); SURVIVAL ANALYSIS;

BACTERIA (MICROORGANISMS);

EID: 5444225275     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2004.06.009     Document Type: Article

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