Neutrophil migration, oxidative metabolism, and adhesion in elderly and young subjects

Inflammation

Volumn 20, Issue 6, 1996, Pages 673-681

  Biasi, D ^a   Carletto, A ^a   Dell'Agnola, C ^a   Caramaschi, P ^a   Montesanti, F ^b   Zavateri, G ^b   Zeminian, S ^a   Bellavite, P ^a   Bambara, L M ^a  

^a UNIVERSITY OF VERONA   (Italy)

^b Ospedaliera de Verona   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

FORMYLMETHIONYLLEUCYLPHENYLALANINE; PHORBOL 13 ACETATE 12 MYRISTATE; RECEPTOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; ZYMOSAN;

ADULT; AEROBIC METABOLISM; AGE; AGED; ARTICLE; CELL ADHESION; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVATION; EXUDATE; FEMALE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; MALE; NEUTROPHIL; NORMAL HUMAN; SIGNAL TRANSDUCTION; SKIN;

ADULT; AGED; AGED, 80 AND OVER; AGING; CELL ADHESION; CHEMOTAXIS, LEUKOCYTE; FEMALE; HUMANS; MALE; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NADPH OXIDASE; NEUTROPHILS; RECEPTORS, FORMYL PEPTIDE; RECEPTORS, IMMUNOLOGIC; RECEPTORS, PEPTIDE; RESPIRATORY BURST; SUPEROXIDES; TETRADECANOYLPHORBOL ACETATE; ZYMOSAN;

EID: 0030446825     PISSN: 03603997     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01488803     Document Type: Article

References (32)

1. VAN EPPS, D. E., and M. L. GARCIA. 1980. Enhancement of neutrophil function as a result of prior exposure to chemotactic factor. J. Clin. Invest. 66:167-175.
2. BRIHEIM, G., O. STENDHAL, B. I. COBLE, and C. DAHLGREN. 1988. Exudate polymorphonuclear leukocytes isolated from chambers are primed for enhanced response to subsequent stimulation with the chemoattractant fMet-Leu-Phe and C3 opsonized yeast particles. Inflammation 12:141-152.
3. BIASI, D., L. M. BAMBARA, A. CARLETTO, M. CARAFFI, M. C. SERRA, S. CHIRUMBOLO, and P. BELLAVITE. 1993. Factor-specific changes in oxidative burst response of human PMNs in skin window exudates. Inflammation 17:13-23.
4. BIASI, D., L. M. BAMBARA, A. CARLETTO, P. CARAMASCHI, M. C. SERRA, C. SANTONASTASO, P. GUZZO, and P. BELLAVITE. 1993. Molecular mechanisms of priming: exudate human PMNs are primed to fMET-LEU-PHE but have normal intracellular calcium and cAMP responses. Bull. Mol. Biol. Med. 18:225-235.
5. PATY, P. B., R. W. GRAEFF, S. J. MATES, and T. K. HUNT. 1990. Superoxide production by wound PMNs. Evidence for increased activity of the NADPH oxidase. Arch. Surg. 125:65-69.
6. BELLAVITE, P., A. CARLETTO, D. BIASI, P. CARAMASCHI, F. POLI, F. SUTTORA, and L. M. BAMBARA. 1994. Studies of skin window exudate human neutrophils. Complex patterns of adherence to serum-coated surfaces in dependence on fMLP doses. Inflammation. 18:575-587.
7. NURCOMBE, H. L., R. C. BUCKNALL, and S. W. EDWARDS. 1991. Neutrophils isolated from the synovial fluid of patients with rheumatoid arthritis: priming and action in vivo. Ann. Rheum. Dis. 50:147-153.
8. WARD, P. A., J. S. WARREN, and K. J. JOHNSONN. 1988. Oxygen radicals, inflammation and tissue injury. Free Rad. Biol. Med. 5:403-408.
9. WEISS, S. J. 1989. Tissue destruction by neutrophils. N. Engl. J Med. 320:365-376.
10. FOLLIN, P., M. P. WYMANN, B. DEWALD, M. CESKA, and C. DAHLGREN. 1991. Human neutrophil migration into skin chambers is associated with production of NAP-1/IL8 and C5a. Eur. J. Haematol. 47:71-76.
11. CORBERAND, J. X., P. F. LAHARRAGUE, and G. FILLOLA. 1986. Neutrophils of healthy aged humans are normal. Mech. Ageing Dev. 36:57-63.
12. ANTONACI, S., E. JIRILLO, M. T. VENTURA, A. R. GAROFALO, and L. BONOMO. 1984. Non-specific immunity in aging: deficiency of monocyte and polymorphonuclear cell-mediated functions. Mech. Ageing Dev. 24:367-375.
13. NIWA, Y., T. KASAMA, Y. MIYACHI, and T. KANOH. 1989. Neutrophil chemotaxis, phagocytosis and parameters of reactive oxygen species in human aging: cross-sectional and longitudinal studies. Life Sci. 44:1655-1664.
14. RABATIC, S., A. SABIONCELLO, D. DEKARIS, and I. KARDUN. 1988. Age related changes in functions of peripheral blood phagocytes. Mech. Ageing Dev. 45:223-229.
15. TORTORELLA, C., A. OTTOLENGHI, P. PUGLIESE, E. JIRILLO, and S. ANTONACI. 1993. Relationship between respiratory burst and adhesiveness capacity in elderly polymorphonuclear cells. Mech. Ageing Dev. 69:53-63.
16. NAGEL, J. E., R. S. PYLE, F. J. CHREST, and W. H. ADLER. 1982. Oxidative metabolism and bactericidal capacity of polymorphonuclear leukocyte from young and aged adults. J. Geronol. 37:529-534.
17. LIPSCHITZ, D. A., K. B. UDUPA, and L. A. BOXER. 1988. The role of calcium in the age-related decline of neutrophil function. Blood 71:659-665.
18. LIGTHART, G. J., J. X. CORBERAND, C. FOURNIER, R. GALANAUD, W. HUMANS, B. KENNES, A. MULLER-HERMELINK, and G. G. STEINMANN. 1984. Admission criteria for immunogerontological studies in man: the SENIEUR protocol. Mech. Ageing Dev. 28:47-55.
19. METCALF, J. A., J. I. GALLIN, W. M. NAUSEEF, and R. K. ROOT. 1986. In: Laboratory Manual of Neutrophil Function. Raven Press, New York.
20. SENN, H. J., and W. F. JUNGI. 1975. Neutrophil migration in health and disease. Semin. Hematol. 12:27-45.
21. BABIOR, B. M., R. S. KIPNES, and J. T. CURNUTTE. 1973. Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent. J. Clin. Invest. 52:741-744.
22. BELLAVITE, P., S. CHIRUMBOLO, C. MANSOLDO, G. GANDINI, and P. DRI. 1992. A simultaneous assay for oxidative metabolism and adhesion of human neutrophils. Evidence for correlations and dissociation of the two responses. J. Leukocyte Biol. 51:329-333.
23. MC LAUGHLIN, B., K. O'MALLEY, and T. G. COTTER. 1986. Age-related differences in granulocyte chemotaxis and degranulation. Clin. Sci. 70:59-62.
24. SERLENGA, E., A. OTTOLENGHI, M. T. VENTURA, A. V. POLIGNANO, C. TORTORELLA, E. JIRILLO, and S. ANTONACI. 1990. Monocyte-polymorph- and lymphocyte-mediated chemotactic responsiveness in the elderly. EOS-Riv. Immunol. Immunopharmacol. 10:28-31.
25. RAO, K. M. K., M. S. CURRIE, J. PABMANABHAN, and H. J. COHEN. 1992. Age-related alterations in actin cytoschleton and receptor expression in human leukocytes. J. Gerontol. 47:B37-B44.
26. RIVNAY, B., S. BERGMAN, M. SHINITZKY, and A. GLOBERSON. 1980. Correlation between membrane viscosity, serum cholesterol, lymphocyte activation and ageing in man. Mech. Ageing Dev. 12:119-126.
27. TORTORELLA, C., A. OTTOLENGHI, P. PUGLIESE, E. JIRILLO, and S. ANTONACI. 1994. Polymorphonuclear cells in elderly subjects. Facts Res. Gerontol. 3:211-220.
28. CRONSTEIN, B. N., S. B. KRAMER, G. WEISSMANN, and R. HIRSHHORN. 1983. Adenosine: a physiological modulator of superoxide anion generation by human neutrophils. J. Exp. Med. 158:1160-1177.
29. 2 generation, respectively. J. Clin. Invest. 85:1150-1157.
30. DELLA BIANCA, V., P. DE TOGNI, M. GRZESKOWIAK, L. M. VICENTINI, and F. DI VIRGILIO. 1986. Cyclic AMP inhibition of phosphoinositide turnover in human neutrophils. Biochim. Biophys. Acta 886:441-447.
31. BELLAVITE, P. 1988. The superoxide-forming enzymatic system of phagotcytes. Free Radical Biol. Med. 4:225-261.
32. IYENGAR, R. 1996. Gating by Cyclic AMP: expanded role for an signaling pathway. Science 271:461-463.