MacrophAging: A cellular and molecular review

Immunobiology

Volumn 210, Issue 2-4, 2005, Pages 121-126

  Sebastián, Carlos ^a   Espia, Marta ^a   Serra, Maria ^a   Celada, Antonio ^a   Lloberas, Jorge ^a  

^a INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

Author keywords

Aging; DNA damage; Immunosenescence; Macrophages

Indexed keywords

CD28 ANTIGEN; COLONY STIMULATING FACTOR 1; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

AGING; ANTIGEN EXPRESSION; CELL AGING; CELL DIFFERENTIATION; CELL FUNCTION; CELL MATURATION; CELL PROLIFERATION; CYTOKINE RELEASE; FUNGUS; GRAM POSITIVE BACTERIUM; IMMUNE SYSTEM; IMMUNOPATHOLOGY; INCIDENCE; INFECTION RESISTANCE; INFECTION SENSITIVITY; INFLAMMATION; INNATE IMMUNITY; MACROPHAGE FUNCTION; MALIGNANT NEOPLASTIC DISEASE; MICROBIAL IMMUNITY; MOLECULAR MECHANICS; MORTALITY; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; REVIEW; SENESCENCE;

EID: 22644444814     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imbio.2005.05.006     Document Type: Review

References (52)

1. S. Akira K. Takeda T. Kaisho Toll-like receptors: Critical proteins linking innate and acquired immunity Nat. Immunol. 2 2001 675-680
2. L. Alexopoulou A.C. Holt R. Medzhitov R.A. Flavell Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3 Nature 413 2001 732-738
3. R. Arking Biology of Aging: Observations and Principles second ed 1998 Sinauer Sunderland
4. M.A. Blasco Immunosenescence phenotypes in the telomerase knockout mouse Springer Semin. Immunopathol. 24 2002 75-85
5. E.D. Boehmer J. Goral D.E. Faunce E.J. Kovacs Age-dependent decrease in Toll-like receptor 4-mediated proinflammatory cytokine production and mitogen-activated protein kinase expression J. Leukoc. Biol. 75 2004 342-349
6. Breitbart, E., Wang, X., Leka, L.S., Dallal, G.E., Meydani, S.N., Stollar, B.D. (2002). Altered memory B-cell homeostasis in human aging. J. Gerontol. A Biol. Sci. Med. Sci. 57, B304-311.
7. S.K. Butcher H. Chahal L. Nayak A. Sinclair N.V. Henriquez E. Sapey D. O'Mahony J.M. Lord Senescence in innate immune responses: Reduced neutrophil phagocytic capacity and CD16 expression in elderly humans J. Leukoc. Biol. 70 2001 881-886
8. A. Celada C. Nathan Macrophage activation revisited Immunol. Today 15 1994 100-102
9. A. Celada M.J. Klemsz R.A. Maki Interferon-gamma activates multiple pathways to regulate the expression of the genes for major histocompatibility class II I-A beta, tumor necrosis factor and complement component C3 in mouse macrophages Eur. J. Immunol. 19 1989 1103-1109
10. G. Colonna-Romano M. Bulati A. Aquino G. Scialabba G. Candore D. Lio M. Motta M. Malaguarnera C. Caruso B cells in the aged: CD27, CD5, and CD40 expression Mech. Ageing Dev. 124 2003 389-393
11. M. Cullell-Young M. Barrachina C. Lopez-Lopez E. Gonalons J. Lloberas C. Soler A. Celada From transcription to cell surface expression, the induction of MHC class II I-A alpha by interferon-gamma in macrophages is regulated at different levels Immunogenetics 53 2001 136-144
12. D.R. Davila C.K. Edwards III S. Arkins J. Simon K.W. Kelley Interferon-gamma-induced priming for secretion of superoxide anion and tumor necrosis factor-alpha declines in macrophages from aged rats FASEB J. 4 1990 2906-2911
13. A.D. Delpedro M.J. Barjavel Z. Mamdouh S. Faure O. Bakouche Signal transduction in LPS-activated aged and young monocytes J. Interferon Cytokine Res. 18 1998 429-437
14. A. Ding S. Hwang R. Schwab Effect of aging on murine macrophages. Diminished response to IFN-gamma for enhanced oxidative metabolism J. Immunol. 153 1994 2146-2152
15. A. Donnini K. Argentati R. Mancini A. Smorlesi B. Bartozzi G. Bernardini M. Provinciali Phenotype, antigen-presenting capacity, and migration of antigen-presenting cells in young and old age Exp. Gerontol. 37 2002 1097-1112
16. R.B. Effros Ageing and the immune system Novartis Found. Symp. 235 2001 130-149
17. R.B. Effros N. Boucher V. Porter X. Zhu C. Spaulding R.L. Walford M. Kronenberg D. Cohen F. Schachter Decline in CD28+ T cells in centenarians and in long-term T cell cultures: A possible cause for both in vivo and in vitro immunosenescence Exp. Gerontol. 29 1994 601-609
18. N. Fabris E. Mocchegiani M. Provinciali Plasticity of neuroendocrine-thymus interactions during aging Exp. Gerontol. 32 1997 415-429
19. M. Garg W. Luo A.M. Kaplan S. Bondada Cellular basis of decreased immune responses to pneumococcal vaccines in aged mice Infect. Immun. 64 1996 4456-4462
20. H. Geiger G. Van Zant The aging of lympho-hematopoietic stem cells Nat. Immunol. 3 2002 329-333
21. A.J. George M.A. Ritter Thymic involution with ageing: Obsolescence or good housekeeping? Immunol. Today 17 1996 267-272
22. A.T. Gewirtz T.A. Navas S. Lyons P.J. Godowski J.L. Madara Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression J. Immunol. 167 2001 1882-1885
23. E. Gonalons M. Barrachina J.A. Garcia-Sanz A. Celada Translational control of MHC class II I-A molecules by IFN-gamma J. Immunol. 161 1998 1837-1843
24. S. Gordon Alternative activation of macrophages Nat. Rev. Immunol. 3 2003 23-35
25. S. Hekimi L. Guarente Genetics and the specificity of the aging process Science 299 2003 1351-1354
26. H. Hemmi T. Kaisho O. Takeuchi S. Sato H. Sanjo K. Hoshino T. Horiuchi H. Tomizawa K. Takeda S. Akira Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway Nat. Immunol. 3 2002 196-200
27. C. Herrero L. Marques J. Lloberas A. Celada IFN-gamma-dependent transcription of MHC class II IA is impaired in macrophages from aged mice J. Clin. Invest. 107 2001 485-493
28. C. Herrero C. Sebastian L. Marques M. Comalada J. Xaus A.F. Valledor J. Lloberas A. Celada Immunosenescence of macrophages: Reduced MHC class II gene expression Exp. Gerontol. 37 2002 389-394
29. B.H. Howard Replicative senescence: Considerations relating to the stability of heterochromatin domains Exp. Gerontol. 31 1996 281-293
30. H. Iwama K. Ohyashiki J.H. Ohyashiki S. Hayashi N. Yahata K. Ando K. Toyama A. Hoshika M. Takasaki M. Mori J.W. Shay Telomeric length and telomerase activity vary with age in peripheral blood cells obtained from normal individuals Hum. Genet. 102 1998 397-402
31. M.S. Kanungo A model for ageing J. Theor. Biol. 53 1975 253-261
32. M.L. Kohut D.S. Senchina K.S. Madden A.E. Martin D.L. Felten J.A. Moynihan Age effects on macrophage function vary by tissue site, nature of stimulant, and exercise behavior Exp. Gerontol. 39 2004 1347-1360
33. P. Kropf S. Herath V. Weber M. Modolell I. Muller Factors influencing Leishmania major infection in IL-4-deficient BALB/c mice Parasite Immunol. 25 2003 439-447
34. P. Liu P.F. Smith I. Appleton C.L. Darlington D.K. Bilkey Nitric oxide synthase and arginase in the rat hippocampus and the entorhinal, perirhinal, postrhinal, and temporal cortices: Regional variations and age-related changes Hippocampus 13 2003a 859-867
35. P. Liu P.F. Smith I. Appleton C.L. Darlington D.K. Bilkey Regional variations and age-related changes in nitric oxide synthase and arginase in the sub-regions of the hippocampus Neuroscience 119 2003b 679-687
36. J. Lloberas A. Celada Effect of aging on macrophage function Exp. Gerontol. 37 2002 1325-1331
37. J. Lloberas C. Soler A. Celada The key role of PU.1/SPI-1 in B cells, myeloid cells and macrophages Immunol. Today 20 1999 184-189
38. R.A. Miller The aging immune system: Primer and prospectus Science 273 1996 70-74
39. T. Ogawa M. Kitagawa K. Hirokawa Age-related changes of human bone marrow: A histometric estimation of proliferative cells, apoptotic cells, T cells, B cells and macrophages Mech. Ageing Dev. 117 2000 57-68
40. V.V. Ogryzko T.H. Hirai V.R. Russanova D.A. Barbie B.H. Howard Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent Mol. Cell Biol. 16 1996 5210-5218
41. G. Pawelec R. Solana Immunosenescence Immunol. Today 18 1997 514-516
42. J. Plowden M. Renshaw-Hoelscher C. Engleman J. Katz S. Sambhara Innate immunity in aging: Impact on macrophage function Aging Cell 3 2004 161-167
43. M. Renshaw J. Rockwell C. Engleman A. Gewirtz J. Katz S. Sambhara Cutting edge: Impaired Toll-like receptor expression and function in aging J. Immunol. 169 2002 4697-4701
44. P. Smith D.W. Dunne P.G. Fallon Defective in vivo induction of functional type 2 cytokine responses in aged mice Eur. J. Immunol. 31 2001 1495-1502
45. R. Solana E. Mariani NK and NK/T cells in human senescence Vaccine 18 2000 1613-1620
46. L.Q. Sun D.W. Lee Q. Zhang W. Xiao E.H. Raabe A. Meeker D. Miao D.L. Huso R.J. Arceci Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG Genes Dev. 18 2004 1035-1046
47. J.L. Villanueva R. Solana M.C. Alonso J. Pena Changes in the expression of HLA-class II antigens on peripheral blood monocytes from aged humans Dis. Markers 8 1990 85-91
48. B. Villeponteau The heterochromatin loss model of aging Exp. Gerontol. 32 1997 383-394
49. C.Q. Wang K.B. Udupa H. Xiao D.A. Lipschitz Effect of age on marrow macrophage number and function Aging (Milano) 7 1995 379-384
50. N. Weng Interplay between telomere length and telomerase in human leukocyte differentiation and aging J. Leukoc. Biol. 70 2001 861-867
51. J. Xaus M. Cardo A.F. Valledor C. Soler J. Lloberas A. Celada Interferon gamma induces the expression of p21waf-1 and arrests macrophage cell cycle, preventing induction of apoptosis Immunity 11 1999 103-113
52. B. Zheng S. Han Y. Takahashi G. Kelsoe Immunosenescence and germinal center reaction Immunol. Rev. 160 1997 63-77