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Volumn 78, Issue 1, 2009, Pages 1-17

Epigenetic gene regulation in stem cells and correlation to cancer

Author keywords

Embryonic stem cells; Epigenetics; Normal and cancerous adult stem progenitor cells

Indexed keywords

BCR ABL PROTEIN; CD24 ANTIGEN; CD34 ANTIGEN; CD44V ANTIGEN; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE INHIBITOR; GENOMIC DNA; GLUTATHIONE TRANSFERASE P1; HISTONE; HISTONE DEACETYLASE INHIBITOR; HOX PROTEIN; RETINOIC ACID; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR JUNB; TRANSCRIPTION FACTOR MSX1; TRANSCRIPTION FACTOR MSX2; TRANSCRIPTION FACTOR NKX3.1; UNCLASSIFIED DRUG;

EID: 67649397334     PISSN: 03014681     EISSN: 14320436     Source Type: Journal    
DOI: 10.1016/j.diff.2009.04.002     Document Type: Review
Times cited : (73)

References (192)
  • 2
    • 18744366334 scopus 로고    scopus 로고
    • Hox regulation of normal and leukemic hematopoietic stem cells
    • Abramovich C., and Humphries R.K. Hox regulation of normal and leukemic hematopoietic stem cells. Current Opinion in Hematology 12 (2005) 210-216
    • (2005) Current Opinion in Hematology , vol.12 , pp. 210-216
    • Abramovich, C.1    Humphries, R.K.2
  • 8
    • 33847287408 scopus 로고    scopus 로고
    • Differences between human embryonic stem cell lines
    • Allegrucci C., and Young L.E. Differences between human embryonic stem cell lines. Human Reproduction Update 13 (2007) 103-120
    • (2007) Human Reproduction Update , vol.13 , pp. 103-120
    • Allegrucci, C.1    Young, L.E.2
  • 12
    • 37549050193 scopus 로고    scopus 로고
    • Epigenetics in embryonic stem cells: regulation of pluripotency and differentiation
    • Atkinson S., and Armstrong L. Epigenetics in embryonic stem cells: regulation of pluripotency and differentiation. Cell and Tissue Research 331 (2008) 23-29
    • (2008) Cell and Tissue Research , vol.331 , pp. 23-29
    • Atkinson, S.1    Armstrong, L.2
  • 13
    • 25844518743 scopus 로고    scopus 로고
    • The many faces of REST oversee epigenetic programming of neuronal genes
    • Ballas N., and Mandel G. The many faces of REST oversee epigenetic programming of neuronal genes. Current Opinion in Neurobiology 15 (2005) 500-506
    • (2005) Current Opinion in Neurobiology , vol.15 , pp. 500-506
    • Ballas, N.1    Mandel, G.2
  • 19
    • 0021086610 scopus 로고
    • Two DNA methyltransferases from murine erythroleukemia cells: purification, sequence specificity, and mode of interaction with DNA
    • Bestor T.H., and Ingram V.M. Two DNA methyltransferases from murine erythroleukemia cells: purification, sequence specificity, and mode of interaction with DNA. Proceedings of the National Academy of Sciences of the United States of America 80 (1983) 5559-5563
    • (1983) Proceedings of the National Academy of Sciences of the United States of America , vol.80 , pp. 5559-5563
    • Bestor, T.H.1    Ingram, V.M.2
  • 20
    • 0022000776 scopus 로고
    • A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA
    • Bird A., Taggart M., Frommer M., Miller O.J., and Macleod D. A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA. Cell 40 (1985) 91-99
    • (1985) Cell , vol.40 , pp. 91-99
    • Bird, A.1    Taggart, M.2    Frommer, M.3    Miller, O.J.4    Macleod, D.5
  • 21
    • 0030021453 scopus 로고    scopus 로고
    • Differentiation pathways and histogenetic aspects of normal and abnormal prostatic growth: a stem cell model
    • Bonkhoff H., and Remberger K. Differentiation pathways and histogenetic aspects of normal and abnormal prostatic growth: a stem cell model. The Prostate 28 (1996) 98-106
    • (1996) The Prostate , vol.28 , pp. 98-106
    • Bonkhoff, H.1    Remberger, K.2
  • 22
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • Bonnet D., and Dick J.E. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nature Medicine 3 (1997) 730-737
    • (1997) Nature Medicine , vol.3 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 24
    • 0142105414 scopus 로고    scopus 로고
    • EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
    • Bracken A.P., Pasini D., Capra M., Prosperini E., Colli E., and Helin K. EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer. The EMBO Journal 22 (2003) 5323-5335
    • (2003) The EMBO Journal , vol.22 , pp. 5323-5335
    • Bracken, A.P.1    Pasini, D.2    Capra, M.3    Prosperini, E.4    Colli, E.5    Helin, K.6
  • 25
    • 0036370406 scopus 로고    scopus 로고
    • Hormonal control of alveolar development and its implications for breast carcinogenesis
    • Brisken C. Hormonal control of alveolar development and its implications for breast carcinogenesis. Journal of Mammary Gland Biology and Neoplasia 7 (2002) 39-48
    • (2002) Journal of Mammary Gland Biology and Neoplasia , vol.7 , pp. 39-48
    • Brisken, C.1
  • 26
    • 0032948005 scopus 로고    scopus 로고
    • Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
    • Cameron E.E., Bachman K.E., Myohanen S., Herman J.G., and Baylin S.B. Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nature Genetics 21 (1999) 103-107
    • (1999) Nature Genetics , vol.21 , pp. 103-107
    • Cameron, E.E.1    Bachman, K.E.2    Myohanen, S.3    Herman, J.G.4    Baylin, S.B.5
  • 29
    • 15044346433 scopus 로고    scopus 로고
    • BCR-ABL-transduced human cord blood cells produce abnormal populations in immunodeficient mice
    • Chalandon Y., Jiang X., Christ O., Loutet S., Thanopoulou E., Eaves A., and Eaves C. BCR-ABL-transduced human cord blood cells produce abnormal populations in immunodeficient mice. Leukemia 19 (2005) 442-448
    • (2005) Leukemia , vol.19 , pp. 442-448
    • Chalandon, Y.1    Jiang, X.2    Christ, O.3    Loutet, S.4    Thanopoulou, E.5    Eaves, A.6    Eaves, C.7
  • 33
    • 28744452913 scopus 로고    scopus 로고
    • A self-renewal assay for cancer stem cells
    • Clarke M.F. A self-renewal assay for cancer stem cells. Cancer Chemotherapy and Pharmacology 56 Suppl. 1 (2005) 64-68
    • (2005) Cancer Chemotherapy and Pharmacology , vol.56 , Issue.SUPPL. 1 , pp. 64-68
    • Clarke, M.F.1
  • 34
    • 0038780904 scopus 로고    scopus 로고
    • Chronic myelogenous leukemia as a paradigm of early cancer and possible curative strategies
    • Clarkson B., Strife A., Wisniewski D., Lambek C.L., and Liu C. Chronic myelogenous leukemia as a paradigm of early cancer and possible curative strategies. Leukemia 17 (2003) 1211-1262
    • (2003) Leukemia , vol.17 , pp. 1211-1262
    • Clarkson, B.1    Strife, A.2    Wisniewski, D.3    Lambek, C.L.4    Liu, C.5
  • 36
    • 0033966406 scopus 로고    scopus 로고
    • piwi encodes a nucleoplasmic factor whose activity modulates the number and division rate of germline stem cells
    • Cox D.N., Chao A., and Lin H. piwi encodes a nucleoplasmic factor whose activity modulates the number and division rate of germline stem cells. Development (Cambridge, England) 127 (2000) 503-514
    • (2000) Development (Cambridge, England) , vol.127 , pp. 503-514
    • Cox, D.N.1    Chao, A.2    Lin, H.3
  • 37
    • 0346100567 scopus 로고    scopus 로고
    • Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors
    • Cozzio A., Passegue E., Ayton P.M., Karsunky H., Cleary M.L., and Weissman I.L. Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors. Genes & Development 17 (2003) 3029-3035
    • (2003) Genes & Development , vol.17 , pp. 3029-3035
    • Cozzio, A.1    Passegue, E.2    Ayton, P.M.3    Karsunky, H.4    Cleary, M.L.5    Weissman, I.L.6
  • 38
    • 0035127758 scopus 로고    scopus 로고
    • Human hepatic stem-like cells isolated using c-kit or CD34 can differentiate into biliary epithelium
    • Crosby H.A., Kelly D.A., and Strain A.J. Human hepatic stem-like cells isolated using c-kit or CD34 can differentiate into biliary epithelium. Gastroenterology 120 (2001) 534-544
    • (2001) Gastroenterology , vol.120 , pp. 534-544
    • Crosby, H.A.1    Kelly, D.A.2    Strain, A.J.3
  • 39
    • 0031683673 scopus 로고    scopus 로고
    • Prostate stem cell compartments: expression of the cell cycle inhibitor p27Kip1 in normal, hyperplastic, and neoplastic cells
    • De Marzo A.M., Meeker A.K., Epstein J.I., and Coffey D.S. Prostate stem cell compartments: expression of the cell cycle inhibitor p27Kip1 in normal, hyperplastic, and neoplastic cells. The American Journal of Pathology 153 (1998) 911-919
    • (1998) The American Journal of Pathology , vol.153 , pp. 911-919
    • De Marzo, A.M.1    Meeker, A.K.2    Epstein, J.I.3    Coffey, D.S.4
  • 40
    • 84965810273 scopus 로고
    • Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice
    • Deome K.B., Faulkin Jr. L.J., Bern H.A., and Blair P.B. Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice. Cancer Research 19 (1959) 515-520
    • (1959) Cancer Research , vol.19 , pp. 515-520
    • Deome, K.B.1    Faulkin Jr., L.J.2    Bern, H.A.3    Blair, P.B.4
  • 41
    • 0037068353 scopus 로고    scopus 로고
    • DNA methylation in cancer: too much, but also too little
    • Ehrlich M. DNA methylation in cancer: too much, but also too little. Oncogene 21 (2002) 5400-5413
    • (2002) Oncogene , vol.21 , pp. 5400-5413
    • Ehrlich, M.1
  • 43
    • 0036736522 scopus 로고    scopus 로고
    • CD34(+) or CD34(-): which is the more primitive?
    • Engelhardt M., Lubbert M., and Guo Y. CD34(+) or CD34(-): which is the more primitive?. Leukemia 16 (2002) 1603-1608
    • (2002) Leukemia , vol.16 , pp. 1603-1608
    • Engelhardt, M.1    Lubbert, M.2    Guo, Y.3
  • 44
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • Evans M.J., and Kaufman M.H. Establishment in culture of pluripotential cells from mouse embryos. Nature 292 (1981) 154-156
    • (1981) Nature , vol.292 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 45
    • 59049105873 scopus 로고    scopus 로고
    • Die hard: are cancer stem cells the Bruce Willises of tumor biology?
    • Fabian A., Barok M., Vereb G., and Szollosi J. Die hard: are cancer stem cells the Bruce Willises of tumor biology?. Cytometry A 75 (2009) 67-74
    • (2009) Cytometry A , vol.75 , pp. 67-74
    • Fabian, A.1    Barok, M.2    Vereb, G.3    Szollosi, J.4
  • 47
    • 34249275353 scopus 로고    scopus 로고
    • Phenotypic plasticity and the epigenetics of human disease
    • Feinberg A.P. Phenotypic plasticity and the epigenetics of human disease. Nature 447 (2007) 433-440
    • (2007) Nature , vol.447 , pp. 433-440
    • Feinberg, A.P.1
  • 48
    • 38349109309 scopus 로고    scopus 로고
    • Small RNAs, big potential: the role of MicroRNAs in stem cell function
    • Foshay K.M., and Gallicano G.I. Small RNAs, big potential: the role of MicroRNAs in stem cell function. Current Stem Cell Research and Therapy 2 (2007) 264-271
    • (2007) Current Stem Cell Research and Therapy , vol.2 , pp. 264-271
    • Foshay, K.M.1    Gallicano, G.I.2
  • 49
    • 0023906672 scopus 로고
    • Proliferation and differentiation of rat neuroepithelial precursor cells in vivo
    • Frederiksen K., and McKay R.D. Proliferation and differentiation of rat neuroepithelial precursor cells in vivo. Journal of Neuroscience 8 (1988) 1144-1151
    • (1988) Journal of Neuroscience , vol.8 , pp. 1144-1151
    • Frederiksen, K.1    McKay, R.D.2
  • 50
    • 0032005387 scopus 로고    scopus 로고
    • Shaping animal body plans in development and evolution by modulation of Hox expression patterns
    • Gellon G., and McGinnis W. Shaping animal body plans in development and evolution by modulation of Hox expression patterns. Bioessays 20 (1998) 116-125
    • (1998) Bioessays , vol.20 , pp. 116-125
    • Gellon, G.1    McGinnis, W.2
  • 52
    • 45549098737 scopus 로고    scopus 로고
    • "Stemness" genomics law governs clinical behavior of human cancer: implications for decision making in disease management
    • Glinsky G.V. "Stemness" genomics law governs clinical behavior of human cancer: implications for decision making in disease management. Journal of Clinical Oncology. 26 (2008) 2846-2853
    • (2008) Journal of Clinical Oncology. , vol.26 , pp. 2846-2853
    • Glinsky, G.V.1
  • 54
    • 34447098370 scopus 로고    scopus 로고
    • A chromatin landmark and transcription initiation at most promoters in human cells
    • Guenther M.G., Levine S.S., Boyer L.A., Jaenisch R., and Young R.A. A chromatin landmark and transcription initiation at most promoters in human cells. Cell 130 (2007) 77-88
    • (2007) Cell , vol.130 , pp. 77-88
    • Guenther, M.G.1    Levine, S.S.2    Boyer, L.A.3    Jaenisch, R.4    Young, R.A.5
  • 56
    • 42249098495 scopus 로고    scopus 로고
    • Histone tail modifications and noncanonical functions of histones: perspectives in cancer epigenetics
    • Hadnagy A., Beaulieu R., and Balicki D. Histone tail modifications and noncanonical functions of histones: perspectives in cancer epigenetics. Molecular Cancer Therapeutics 7 (2008) 740-748
    • (2008) Molecular Cancer Therapeutics , vol.7 , pp. 740-748
    • Hadnagy, A.1    Beaulieu, R.2    Balicki, D.3
  • 57
    • 34548455927 scopus 로고    scopus 로고
    • Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
    • Hermann P.C., Huber S.L., Herrler T., Aicher A., Ellwart J.W., Guba M., Bruns C.J., and Heeschen C. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 1 (2007) 313-323
    • (2007) Cell Stem Cell , vol.1 , pp. 313-323
    • Hermann, P.C.1    Huber, S.L.2    Herrler, T.3    Aicher, A.4    Ellwart, J.W.5    Guba, M.6    Bruns, C.J.7    Heeschen, C.8
  • 59
    • 0016439429 scopus 로고
    • DNA modification mechanisms and gene activity during development
    • Holliday R., and Pugh J.E. DNA modification mechanisms and gene activity during development. Science 187 (1975) 226-232
    • (1975) Science , vol.187 , pp. 226-232
    • Holliday, R.1    Pugh, J.E.2
  • 63
    • 39449090031 scopus 로고    scopus 로고
    • CD44+ CD24(-) prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis
    • Hurt E.M., Kawasaki B.T., Klarmann G.J., Thomas S.B., and Farrar W.L. CD44+ CD24(-) prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis. British Journal of Cancer 98 (2008) 756-765
    • (2008) British Journal of Cancer , vol.98 , pp. 756-765
    • Hurt, E.M.1    Kawasaki, B.T.2    Klarmann, G.J.3    Thomas, S.B.4    Farrar, W.L.5
  • 67
    • 33847034841 scopus 로고    scopus 로고
    • Strengths and limitations of the neurosphere culture system
    • Jensen J.B., and Parmar M. Strengths and limitations of the neurosphere culture system. Molecular Neurobiology 34 (2006) 153-161
    • (2006) Molecular Neurobiology , vol.34 , pp. 153-161
    • Jensen, J.B.1    Parmar, M.2
  • 68
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein T., and Allis C.D. Translating the histone code. Science 293 (2001) 1074-1080
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 69
    • 0035839057 scopus 로고    scopus 로고
    • The role of DNA methylation in mammalian epigenetics
    • Jones P.A., and Takai D. The role of DNA methylation in mammalian epigenetics. Science 293 (2001) 1068-1070
    • (2001) Science , vol.293 , pp. 1068-1070
    • Jones, P.A.1    Takai, D.2
  • 70
    • 0027467238 scopus 로고
    • Epithelial-mesenchymal interactions are required for msx 1 and msx 2 gene expression in the developing murine molar tooth
    • Jowett A.K., Vainio S., Ferguson M.W., Sharpe P.T., and Thesleff I. Epithelial-mesenchymal interactions are required for msx 1 and msx 2 gene expression in the developing murine molar tooth. Development 117 (1993) 461-470
    • (1993) Development , vol.117 , pp. 461-470
    • Jowett, A.K.1    Vainio, S.2    Ferguson, M.W.3    Sharpe, P.T.4    Thesleff, I.5
  • 74
    • 58149185600 scopus 로고    scopus 로고
    • Exploring the origins of the normal prostate and prostate cancer stem cell
    • Kasper S. Exploring the origins of the normal prostate and prostate cancer stem cell. Stem Cell Reviews 4 (2008) 193-201
    • (2008) Stem Cell Reviews , vol.4 , pp. 193-201
    • Kasper, S.1
  • 77
    • 18844396119 scopus 로고    scopus 로고
    • Embryonic stem cell differentiation: emergence of a new era in biology and medicine
    • Keller G. Embryonic stem cell differentiation: emergence of a new era in biology and medicine. Genes & Development 19 (2005) 1129-1155
    • (2005) Genes & Development , vol.19 , pp. 1129-1155
    • Keller, G.1
  • 78
    • 0029837610 scopus 로고    scopus 로고
    • Evidence of stem cells in the adult prostatic epithelium based upon responsiveness to mesenchymal inductors
    • Kinbara H., Cunha G.R., Boutin E., Hayashi N., and Kawamura J. Evidence of stem cells in the adult prostatic epithelium based upon responsiveness to mesenchymal inductors. The Prostate 29 (1996) 107-116
    • (1996) The Prostate , vol.29 , pp. 107-116
    • Kinbara, H.1    Cunha, G.R.2    Boutin, E.3    Hayashi, N.4    Kawamura, J.5
  • 79
    • 47149097853 scopus 로고    scopus 로고
    • Epigenetic gene silencing in the Wnt pathway in breast cancer
    • Klarmann G.J., Decker A., and Farrar W.L. Epigenetic gene silencing in the Wnt pathway in breast cancer. Epigenetics 3 (2008) 59-63
    • (2008) Epigenetics , vol.3 , pp. 59-63
    • Klarmann, G.J.1    Decker, A.2    Farrar, W.L.3
  • 85
    • 0016221697 scopus 로고
    • Chromatin structure: a repeating unit of histones and DNA
    • Kornberg R.D. Chromatin structure: a repeating unit of histones and DNA. Science 184 (1974) 868-871
    • (1974) Science , vol.184 , pp. 868-871
    • Kornberg, R.D.1
  • 86
    • 35548934558 scopus 로고    scopus 로고
    • MLL translocations, histone modifications and leukaemia stem-cell development
    • Krivtsov A.V., and Armstrong S.A. MLL translocations, histone modifications and leukaemia stem-cell development. Nature Reviews 7 (2007) 823-833
    • (2007) Nature Reviews , vol.7 , pp. 823-833
    • Krivtsov, A.V.1    Armstrong, S.A.2
  • 87
    • 21744443648 scopus 로고    scopus 로고
    • Bone marrow as a home of heterogenous populations of nonhematopoietic stem cells
    • Kucia M., Reca R., Jala V.R., Dawn B., Ratajczak J., and Ratajczak M.Z. Bone marrow as a home of heterogenous populations of nonhematopoietic stem cells. Leukemia 19 (2005) 1118-1127
    • (2005) Leukemia , vol.19 , pp. 1118-1127
    • Kucia, M.1    Reca, R.2    Jala, V.R.3    Dawn, B.4    Ratajczak, J.5    Ratajczak, M.Z.6
  • 88
    • 0036723652 scopus 로고    scopus 로고
    • I-mfa domain proteins interact with Axin and affect its regulation of the Wnt and c-Jun N-terminal kinase signaling pathways
    • Kusano S., and Raab-Traub N. I-mfa domain proteins interact with Axin and affect its regulation of the Wnt and c-Jun N-terminal kinase signaling pathways. Molecular and Cellular Biology 22 (2002) 6393-6405
    • (2002) Molecular and Cellular Biology , vol.22 , pp. 6393-6405
    • Kusano, S.1    Raab-Traub, N.2
  • 91
    • 0037111831 scopus 로고    scopus 로고
    • Histone methyltransferase activity associated with a human multiprotein complex containing the enhancer of Zeste protein
    • Kuzmichev A., Nishioka K., Erdjument-Bromage H., Tempst P., and Reinberg D. Histone methyltransferase activity associated with a human multiprotein complex containing the enhancer of Zeste protein. Genes & Development 16 (2002) 2893-2905
    • (2002) Genes & Development , vol.16 , pp. 2893-2905
    • Kuzmichev, A.1    Nishioka, K.2    Erdjument-Bromage, H.3    Tempst, P.4    Reinberg, D.5
  • 94
    • 59049098238 scopus 로고    scopus 로고
    • Neural stem cells: mechanisms of fate specification and nuclear reprogramming in regenerative medicine
    • Lederer C.W., and Santama N. Neural stem cells: mechanisms of fate specification and nuclear reprogramming in regenerative medicine. Biotechnology Journal 3 (2008) 1521-1538
    • (2008) Biotechnology Journal , vol.3 , pp. 1521-1538
    • Lederer, C.W.1    Santama, N.2
  • 96
    • 38349078700 scopus 로고    scopus 로고
    • Inhibition of DNA methylation is involved in transdifferentiation of myoblasts into smooth muscle cells
    • Lee W.J., and Kim H.J. Inhibition of DNA methylation is involved in transdifferentiation of myoblasts into smooth muscle cells. Molecules and Cells 24 (2007) 441-444
    • (2007) Molecules and Cells , vol.24 , pp. 441-444
    • Lee, W.J.1    Kim, H.J.2
  • 97
    • 0037673984 scopus 로고    scopus 로고
    • Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
    • Lessard J., and Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 423 (2003) 255-260
    • (2003) Nature , vol.423 , pp. 255-260
    • Lessard, J.1    Sauvageau, G.2
  • 100
    • 36249025636 scopus 로고    scopus 로고
    • Wnt signaling, stem cells, and the cellular origin of breast cancer
    • Lindvall C., Bu W., Williams B.O., and Li Y. Wnt signaling, stem cells, and the cellular origin of breast cancer. Stem Cell Reviews 3 (2007) 157-168
    • (2007) Stem Cell Reviews , vol.3 , pp. 157-168
    • Lindvall, C.1    Bu, W.2    Williams, B.O.3    Li, Y.4
  • 102
    • 30344470789 scopus 로고    scopus 로고
    • Transcript profiling in peripheral T-cell lymphoma, not otherwise specified, and diffuse large B-cell lymphoma identifies distinct tumor profile signatures
    • Mahadevan D., Spier C., Della Croce K., Miller S., George B., Riley C., Warner S., Grogan T.M., and Miller T.P. Transcript profiling in peripheral T-cell lymphoma, not otherwise specified, and diffuse large B-cell lymphoma identifies distinct tumor profile signatures. Molecular Cancer Therapeutics 4 (2005) 1867-1879
    • (2005) Molecular Cancer Therapeutics , vol.4 , pp. 1867-1879
    • Mahadevan, D.1    Spier, C.2    Della Croce, K.3    Miller, S.4    George, B.5    Riley, C.6    Warner, S.7    Grogan, T.M.8    Miller, T.P.9
  • 104
    • 40849134548 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor treatment downregulates VLA-4 adhesion in hematopoietic stem cells and acute myeloid leukemia blast cells
    • Mahlknecht U., and Schonbein C. Histone deacetylase inhibitor treatment downregulates VLA-4 adhesion in hematopoietic stem cells and acute myeloid leukemia blast cells. Haematologica 93 (2008) 443-446
    • (2008) Haematologica , vol.93 , pp. 443-446
    • Mahlknecht, U.1    Schonbein, C.2
  • 105
    • 33846200332 scopus 로고    scopus 로고
    • Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis
    • Mann J., Oakley F., Akiboye F., Elsharkawy A., Thorne A.W., and Mann D.A. Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis. Cell Death and Differentiation 14 (2007) 275-285
    • (2007) Cell Death and Differentiation , vol.14 , pp. 275-285
    • Mann, J.1    Oakley, F.2    Akiboye, F.3    Elsharkawy, A.4    Thorne, A.W.5    Mann, D.A.6
  • 106
    • 2042510518 scopus 로고    scopus 로고
    • Reprogramming erythroleuekmia cells to terminal differentiation and terminal cell division
    • Matushansky I., Radparvar F., Rekhtman N., and Skoultchi A. Reprogramming erythroleuekmia cells to terminal differentiation and terminal cell division. Frontiers in Bioscience 5 (2000) D488-D492
    • (2000) Frontiers in Bioscience , vol.5
    • Matushansky, I.1    Radparvar, F.2    Rekhtman, N.3    Skoultchi, A.4
  • 107
    • 35348814900 scopus 로고    scopus 로고
    • Concise review: hematopoietic stem cells and tissue stem cells: current concepts and unanswered questions
    • Metcalf D. Concise review: hematopoietic stem cells and tissue stem cells: current concepts and unanswered questions. Stem Cells (Dayton, Ohio) 25 (2007) 2390-2395
    • (2007) Stem Cells (Dayton, Ohio) , vol.25 , pp. 2390-2395
    • Metcalf, D.1
  • 108
    • 53649093784 scopus 로고    scopus 로고
    • Accumulation of malignant renal stem cells is associated with epigenetic changes in normal renal progenitor genes
    • Metsuyanim S., Pode-Shakked N., Schmidt-Ott K.M., Keshet G., Rechavi G., Blumental D., and Dekel B. Accumulation of malignant renal stem cells is associated with epigenetic changes in normal renal progenitor genes. Stem Cells 26 (2008) 1808-1817
    • (2008) Stem Cells , vol.26 , pp. 1808-1817
    • Metsuyanim, S.1    Pode-Shakked, N.2    Schmidt-Ott, K.M.3    Keshet, G.4    Rechavi, G.5    Blumental, D.6    Dekel, B.7
  • 109
    • 29244433742 scopus 로고    scopus 로고
    • Leukemogenic MLL fusion proteins bind across a broad region of the Hox a9 locus, promoting transcription and multiple histone modifications
    • Milne T.A., Martin M.E., Brock H.W., Slany R.K., and Hess J.L. Leukemogenic MLL fusion proteins bind across a broad region of the Hox a9 locus, promoting transcription and multiple histone modifications. Cancer Research 65 (2005) 11367-11374
    • (2005) Cancer Research , vol.65 , pp. 11367-11374
    • Milne, T.A.1    Martin, M.E.2    Brock, H.W.3    Slany, R.K.4    Hess, J.L.5
  • 110
    • 52649091291 scopus 로고    scopus 로고
    • Recent progress on normal and malignant pancreatic stem/progenitor cell research: therapeutic implications for the treatment of type 1 or 2 diabetes mellitus and aggressive pancreatic cancer
    • Mimeault M., and Batra S.K. Recent progress on normal and malignant pancreatic stem/progenitor cell research: therapeutic implications for the treatment of type 1 or 2 diabetes mellitus and aggressive pancreatic cancer. Gut 57 (2008) 1456-1468
    • (2008) Gut , vol.57 , pp. 1456-1468
    • Mimeault, M.1    Batra, S.K.2
  • 113
    • 34249692139 scopus 로고    scopus 로고
    • The polycomb group BMI1 gene is a molecular marker for predicting prognosis of chronic myeloid leukemia
    • Mohty M., Yong A.S., Szydlo R.M., Apperley J.F., and Melo J.V. The polycomb group BMI1 gene is a molecular marker for predicting prognosis of chronic myeloid leukemia. Blood 110 (2007) 380-383
    • (2007) Blood , vol.110 , pp. 380-383
    • Mohty, M.1    Yong, A.S.2    Szydlo, R.M.3    Apperley, J.F.4    Melo, J.V.5
  • 114
    • 0038304480 scopus 로고    scopus 로고
    • Precursors of neurons, neuroglia, and ependymal cells in the CNS: what are they? Where are they from? How do they get where they are going?
    • Morest D.K., and Silver J. Precursors of neurons, neuroglia, and ependymal cells in the CNS: what are they? Where are they from? How do they get where they are going?. Glia 43 (2003) 6-18
    • (2003) Glia , vol.43 , pp. 6-18
    • Morest, D.K.1    Silver, J.2
  • 116
    • 0033525587 scopus 로고    scopus 로고
    • Prospective identification, isolation by flow cytometry, and in vivo self-renewal of multipotent mammalian neural crest stem cells
    • Morrison S.J., White P.M., Zock C., and Anderson D.J. Prospective identification, isolation by flow cytometry, and in vivo self-renewal of multipotent mammalian neural crest stem cells. Cell 96 (1999) 737-749
    • (1999) Cell , vol.96 , pp. 737-749
    • Morrison, S.J.1    White, P.M.2    Zock, C.3    Anderson, D.J.4
  • 117
    • 33645734361 scopus 로고    scopus 로고
    • ATRA resolves the differentiation block in t(15;17) acute myeloid leukemia by restoring PU.1 expression
    • Mueller B.U., Pabst T., Fos J., Petkovic V., Fey M.F., Asou N., Buergi U., and Tenen D.G. ATRA resolves the differentiation block in t(15;17) acute myeloid leukemia by restoring PU.1 expression. Blood 107 (2006) 3330-3338
    • (2006) Blood , vol.107 , pp. 3330-3338
    • Mueller, B.U.1    Pabst, T.2    Fos, J.3    Petkovic, V.4    Fey, M.F.5    Asou, N.6    Buergi, U.7    Tenen, D.G.8
  • 118
    • 37349051445 scopus 로고    scopus 로고
    • The human insulin gene displays transcriptionally active epigenetic marks in islet-derived mesenchymal precursor cells in the absence of insulin expression
    • Mutskov V., Raaka B.M., Felsenfeld G., and Gershengorn M.C. The human insulin gene displays transcriptionally active epigenetic marks in islet-derived mesenchymal precursor cells in the absence of insulin expression. Stem Cells 25 (2007) 3223-3233
    • (2007) Stem Cells , vol.25 , pp. 3223-3233
    • Mutskov, V.1    Raaka, B.M.2    Felsenfeld, G.3    Gershengorn, M.C.4
  • 122
    • 0032102949 scopus 로고    scopus 로고
    • Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells
    • Okano M., Xie S., and Li E. Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells. Nucleic Acids Research 26 (1998) 2536-2540
    • (1998) Nucleic Acids Research , vol.26 , pp. 2536-2540
    • Okano, M.1    Xie, S.2    Li, E.3
  • 123
    • 0141785202 scopus 로고    scopus 로고
    • Gene repression by Polycomb group protein complexes: a distinct complex for every occasion?
    • Otte A.P., and Kwaks T.H. Gene repression by Polycomb group protein complexes: a distinct complex for every occasion?. Current Opinion in Genetics and Development 13 (2003) 448-454
    • (2003) Current Opinion in Genetics and Development , vol.13 , pp. 448-454
    • Otte, A.P.1    Kwaks, T.H.2
  • 124
    • 34848885467 scopus 로고    scopus 로고
    • Interplay between chromatin remodelers and protein arginine methyltransferases
    • Pal S., and Sif S. Interplay between chromatin remodelers and protein arginine methyltransferases. Journal of Cellular Physiology 213 (2007) 306-315
    • (2007) Journal of Cellular Physiology , vol.213 , pp. 306-315
    • Pal, S.1    Sif, S.2
  • 128
    • 28444482382 scopus 로고    scopus 로고
    • Leukemic stem cells: where do they come from?
    • Passegue E., and Weissman I.L. Leukemic stem cells: where do they come from?. Stem Cell Reviews 1 (2005) 181-188
    • (2005) Stem Cell Reviews , vol.1 , pp. 181-188
    • Passegue, E.1    Weissman, I.L.2
  • 129
    • 0142039054 scopus 로고    scopus 로고
    • A DNA target of 30 bp is sufficient for RNA-directed DNA methylation
    • Pelissier T., and Wassenegger M. A DNA target of 30 bp is sufficient for RNA-directed DNA methylation. RNA 6 (2000) 55-65
    • (2000) RNA , vol.6 , pp. 55-65
    • Pelissier, T.1    Wassenegger, M.2
  • 130
    • 33745083936 scopus 로고    scopus 로고
    • The emerging roles of DNA methylation in the clinical management of prostate cancer
    • Perry A.S., Foley R., Woodson K., and Lawler M. The emerging roles of DNA methylation in the clinical management of prostate cancer. Endocrine-Related Cancer 13 (2006) 357-377
    • (2006) Endocrine-Related Cancer , vol.13 , pp. 357-377
    • Perry, A.S.1    Foley, R.2    Woodson, K.3    Lawler, M.4
  • 132
    • 42749089216 scopus 로고    scopus 로고
    • Communications between bone cells and hematopoietic stem cells
    • Porter R.L., and Calvi L.M. Communications between bone cells and hematopoietic stem cells. Archives of Biochemistry and Biophysics 473 (2008) 193-200
    • (2008) Archives of Biochemistry and Biophysics , vol.473 , pp. 193-200
    • Porter, R.L.1    Calvi, L.M.2
  • 134
    • 0028890357 scopus 로고
    • The developmental pattern of androgen receptor expression in rat prostate lobes is altered after neonatal exposure to estrogen
    • Prins G.S., and Birch L. The developmental pattern of androgen receptor expression in rat prostate lobes is altered after neonatal exposure to estrogen. Endocrinology 136 (1995) 1303-1314
    • (1995) Endocrinology , vol.136 , pp. 1303-1314
    • Prins, G.S.1    Birch, L.2
  • 136
    • 0023196308 scopus 로고
    • Genomic imprinting determines methylation of parental alleles in transgenic mice
    • Reik W., Collick A., Norris M.L., Barton S.C., and Surani M.A. Genomic imprinting determines methylation of parental alleles in transgenic mice. Nature 328 (1987) 248-251
    • (1987) Nature , vol.328 , pp. 248-251
    • Reik, W.1    Collick, A.2    Norris, M.L.3    Barton, S.C.4    Surani, M.A.5
  • 137
    • 35348868573 scopus 로고    scopus 로고
    • Epigenetic regulation of normal and malignant hematopoiesis
    • Rice K.L., Hormaeche I., and Licht J.D. Epigenetic regulation of normal and malignant hematopoiesis. Oncogene 26 (2007) 6697-6714
    • (2007) Oncogene , vol.26 , pp. 6697-6714
    • Rice, K.L.1    Hormaeche, I.2    Licht, J.D.3
  • 138
    • 0016692220 scopus 로고
    • X inactivation, differentiation, and DNA methylation
    • Riggs A.D. X inactivation, differentiation, and DNA methylation. Cytogenetics and Cell Genetics 14 (1975) 9-25
    • (1975) Cytogenetics and Cell Genetics , vol.14 , pp. 9-25
    • Riggs, A.D.1
  • 141
    • 35848943667 scopus 로고    scopus 로고
    • Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging
    • Rossi D.J., Seita J., Czechowicz A., Bhattacharya D., Bryder D., and Weissman I.L. Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging. Cell Cycle (Georgetown, Tex) 6 (2007) 2371-2376
    • (2007) Cell Cycle (Georgetown, Tex) , vol.6 , pp. 2371-2376
    • Rossi, D.J.1    Seita, J.2    Czechowicz, A.3    Bhattacharya, D.4    Bryder, D.5    Weissman, I.L.6
  • 142
    • 38449083769 scopus 로고    scopus 로고
    • Status of genomic imprinting in human embryonic stem cells as revealed by a large cohort of independently derived and maintained lines
    • Rugg-Gunn P.J., Ferguson-Smith A.C., and Pedersen R.A. Status of genomic imprinting in human embryonic stem cells as revealed by a large cohort of independently derived and maintained lines. Human Molecular Genetics 16 Spec No. 2 (2007) R243-R251
    • (2007) Human Molecular Genetics , vol.16 , Issue.Spec 2
    • Rugg-Gunn, P.J.1    Ferguson-Smith, A.C.2    Pedersen, R.A.3
  • 143
    • 1542636969 scopus 로고    scopus 로고
    • Identification of maspin and S100P as novel hypomethylation targets in pancreatic cancer using global gene expression profiling
    • Sato N., Fukushima N., Matsubayashi H., and Goggins M. Identification of maspin and S100P as novel hypomethylation targets in pancreatic cancer using global gene expression profiling. Oncogene 23 (2004) 1531-1538
    • (2004) Oncogene , vol.23 , pp. 1531-1538
    • Sato, N.1    Fukushima, N.2    Matsubayashi, H.3    Goggins, M.4
  • 145
    • 0037079708 scopus 로고    scopus 로고
    • The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors
    • Scharenberg C.W., Harkey M.A., and Torok-Storb B. The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors. Blood 99 (2002) 507-512
    • (2002) Blood , vol.99 , pp. 507-512
    • Scharenberg, C.W.1    Harkey, M.A.2    Torok-Storb, B.3
  • 148
    • 2942691389 scopus 로고    scopus 로고
    • Stem cell origin of cancer and differentiation therapy
    • Sell S. Stem cell origin of cancer and differentiation therapy. Critical Review in Oncology/Hematology 51 (2004) 1-28
    • (2004) Critical Review in Oncology/Hematology , vol.51 , pp. 1-28
    • Sell, S.1
  • 149
    • 35349006314 scopus 로고    scopus 로고
    • Histone lysine demethylases: emerging roles in development, physiology and disease
    • Shi Y. Histone lysine demethylases: emerging roles in development, physiology and disease. Nature Reviews. Genetics 8 (2007) 829-833
    • (2007) Nature Reviews. Genetics , vol.8 , pp. 829-833
    • Shi, Y.1
  • 150
    • 0036900214 scopus 로고    scopus 로고
    • Limiting dilution analysis for estimating the frequency of hematopoietic stem cells: uncertainty and significance
    • Sieburg H.B., Cho R.H., and Muller-Sieburg C.E. Limiting dilution analysis for estimating the frequency of hematopoietic stem cells: uncertainty and significance. Experimental Hematology 30 (2002) 1436-1443
    • (2002) Experimental Hematology , vol.30 , pp. 1436-1443
    • Sieburg, H.B.1    Cho, R.H.2    Muller-Sieburg, C.E.3
  • 151
    • 0028354154 scopus 로고
    • Characterization and enrichment of fetal rat hepatoblasts by immunoadsorption ("panning") and fluorescence-activated cell sorting
    • Sigal S.H., Brill S., Reid L.M., Zvibel I., Gupta S., Hixson D., Faris R., and Holst P.A. Characterization and enrichment of fetal rat hepatoblasts by immunoadsorption ("panning") and fluorescence-activated cell sorting. Hepatology (Baltimore, MD) 19 (1994) 999-1006
    • (1994) Hepatology (Baltimore, MD) , vol.19 , pp. 999-1006
    • Sigal, S.H.1    Brill, S.2    Reid, L.M.3    Zvibel, I.4    Gupta, S.5    Hixson, D.6    Faris, R.7    Holst, P.A.8
  • 156
    • 0023889974 scopus 로고
    • A morphologically distinct candidate for an epithelial stem cell in mouse mammary gland
    • Smith G.H., and Medina D. A morphologically distinct candidate for an epithelial stem cell in mouse mammary gland. Journal of Cell Science 90 Pt 1 (1988) 173-183
    • (1988) Journal of Cell Science , vol.90 , Issue.PART 1 , pp. 173-183
    • Smith, G.H.1    Medina, D.2
  • 159
    • 27744587735 scopus 로고    scopus 로고
    • PU.1 inhibits the erythroid program by binding to GATA-1 on DNA and creating a repressive chromatin structure
    • Stopka T., Amanatullah D.F., Papetti M., and Skoultchi A.I. PU.1 inhibits the erythroid program by binding to GATA-1 on DNA and creating a repressive chromatin structure. The EMBO Journal 24 (2005) 3712-3723
    • (2005) The EMBO Journal , vol.24 , pp. 3712-3723
    • Stopka, T.1    Amanatullah, D.F.2    Papetti, M.3    Skoultchi, A.I.4
  • 164
  • 167
    • 34548403440 scopus 로고    scopus 로고
    • Intracellular translocation of glutathione S-transferase pi during oligodendrocyte differentiation in adult rat cerebral cortex in vivo
    • Tamura Y., Kataoka Y., Cui Y., Takamori Y., Watanabe Y., and Yamada H. Intracellular translocation of glutathione S-transferase pi during oligodendrocyte differentiation in adult rat cerebral cortex in vivo. Neuroscience 148 (2007) 535-540
    • (2007) Neuroscience , vol.148 , pp. 535-540
    • Tamura, Y.1    Kataoka, Y.2    Cui, Y.3    Takamori, Y.4    Watanabe, Y.5    Yamada, H.6
  • 169
    • 0037968549 scopus 로고    scopus 로고
    • Gene expression analysis of purified hematopoietic stem cells and committed progenitors
    • Terskikh A.V., Miyamoto T., Chang C., Diatchenko L., and Weissman I.L. Gene expression analysis of purified hematopoietic stem cells and committed progenitors. Blood 102 (2003) 94-101
    • (2003) Blood , vol.102 , pp. 94-101
    • Terskikh, A.V.1    Miyamoto, T.2    Chang, C.3    Diatchenko, L.4    Weissman, I.L.5
  • 171
    • 0028225780 scopus 로고
    • Rapid and sustained hematopoietic recovery in lethally irradiated mice transplanted with purified Thy-1.1lo Lin-Sca-1+ hematopoietic stem cells
    • Uchida N., Aguila H.L., Fleming W.H., Jerabek L., and Weissman I.L. Rapid and sustained hematopoietic recovery in lethally irradiated mice transplanted with purified Thy-1.1lo Lin-Sca-1+ hematopoietic stem cells. Blood 83 (1994) 3758-3779
    • (1994) Blood , vol.83 , pp. 3758-3779
    • Uchida, N.1    Aguila, H.L.2    Fleming, W.H.3    Jerabek, L.4    Weissman, I.L.5
  • 173
    • 33645417002 scopus 로고    scopus 로고
    • The continuum of stem cell transdifferentiation: possibility of hematopoietic stem cell plasticity with concurrent CD45 expression
    • Udani V.M. The continuum of stem cell transdifferentiation: possibility of hematopoietic stem cell plasticity with concurrent CD45 expression. Stem Cells Development 15 (2006) 1-3
    • (2006) Stem Cells Development , vol.15 , pp. 1-3
    • Udani, V.M.1
  • 176
    • 0037183884 scopus 로고    scopus 로고
    • Little evidence for developmental plasticity of adult hematopoietic stem cells
    • Wagers A.J., Sherwood R.I., Christensen J.L., and Weissman I.L. Little evidence for developmental plasticity of adult hematopoietic stem cells. Science 297 (2002) 2256-2259
    • (2002) Science , vol.297 , pp. 2256-2259
    • Wagers, A.J.1    Sherwood, R.I.2    Christensen, J.L.3    Weissman, I.L.4
  • 178
    • 33644560281 scopus 로고    scopus 로고
    • Cancer stem cells: an old idea-a paradigm shift
    • (discussion 1886-1895)
    • Wicha M.S., Liu S., and Dontu G. Cancer stem cells: an old idea-a paradigm shift. Cancer Research 66 (2006) 1883-1890 (discussion 1886-1895)
    • (2006) Cancer Research , vol.66 , pp. 1883-1890
    • Wicha, M.S.1    Liu, S.2    Dontu, G.3
  • 179
    • 36849023295 scopus 로고    scopus 로고
    • Differential control of Wnt target genes involves epigenetic mechanisms and selective promoter occupancy by T-cell factors
    • Wohrle S., Wallmen B., and Hecht A. Differential control of Wnt target genes involves epigenetic mechanisms and selective promoter occupancy by T-cell factors. Molecular Cell Biology 27 (2007) 8164-8177
    • (2007) Molecular Cell Biology , vol.27 , pp. 8164-8177
    • Wohrle, S.1    Wallmen, B.2    Hecht, A.3
  • 182
    • 39449106321 scopus 로고    scopus 로고
    • Persistence of CD133+ cells in human and mouse glioma cell lines: detailed characterization of GL261 glioma cells with cancer stem cell-like properties
    • Wu A., Oh S., Wiesner S.M., Ericson K., Chen L., Hall W.A., Champoux P.E., Low W.C., and Ohlfest J.R. Persistence of CD133+ cells in human and mouse glioma cell lines: detailed characterization of GL261 glioma cells with cancer stem cell-like properties. Stem Cells Development 17 (2008) 173-184
    • (2008) Stem Cells Development , vol.17 , pp. 173-184
    • Wu, A.1    Oh, S.2    Wiesner, S.M.3    Ericson, K.4    Chen, L.5    Hall, W.A.6    Champoux, P.E.7    Low, W.C.8    Ohlfest, J.R.9
  • 183
    • 0032769445 scopus 로고    scopus 로고
    • Cloning, expression and chromosome locations of the human DNMT3 gene family
    • Xie S., Wang Z., Okano M., Nogami M., Li Y., He W.W., Okumura K., and Li E. Cloning, expression and chromosome locations of the human DNMT3 gene family. Gene 236 (1999) 87-95
    • (1999) Gene , vol.236 , pp. 87-95
    • Xie, S.1    Wang, Z.2    Okano, M.3    Nogami, M.4    Li, Y.5    He, W.W.6    Okumura, K.7    Li, E.8
  • 185
    • 0038281349 scopus 로고    scopus 로고
    • JunB gene expression is inactivated by methylation in chronic myeloid leukemia
    • Yang M.Y., Liu T.C., Chang J.G., Lin P.M., and Lin S.F. JunB gene expression is inactivated by methylation in chronic myeloid leukemia. Blood 101 (2003) 3205-3211
    • (2003) Blood , vol.101 , pp. 3205-3211
    • Yang, M.Y.1    Liu, T.C.2    Chang, J.G.3    Lin, P.M.4    Lin, S.F.5
  • 189
    • 42349083585 scopus 로고    scopus 로고
    • Genetic programming of liver and pancreas progenitors: lessons for stem-cell differentiation
    • Zaret K.S. Genetic programming of liver and pancreas progenitors: lessons for stem-cell differentiation. Nature Reviews Genetics 9 (2008) 329-340
    • (2008) Nature Reviews Genetics , vol.9 , pp. 329-340
    • Zaret, K.S.1
  • 190
    • 48549097232 scopus 로고    scopus 로고
    • Derepression in the desert: the third workshop on clinical translation of epigenetics in cancer therapeutics
    • Zelent A., Petrie K., Boix-Chornet M., Melnick A.M., Waxman S., and Gore S.D. Derepression in the desert: the third workshop on clinical translation of epigenetics in cancer therapeutics. Cancer Research 68 (2008) 4967-4970
    • (2008) Cancer Research , vol.68 , pp. 4967-4970
    • Zelent, A.1    Petrie, K.2    Boix-Chornet, M.3    Melnick, A.M.4    Waxman, S.5    Gore, S.D.6


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