Shaping animal body plans in development and evolution by modulation of Hox expression patterns

BioEssays

Volumn 20, Issue 2, 1998, Pages 116-125

  Gellon, Gabriel ^a,b   McGinnis, William ^b  

^a YALE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSECT PROTEIN;

ANIMAL; CELL DIFFERENTIATION; DROSOPHILA; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HOMEOBOX; MOLECULAR EVOLUTION; MORPHOGENESIS; PHYSIOLOGY; REVIEW;

ANIMALS; CELL DIFFERENTIATION; DROSOPHILA; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, HOMEOBOX; INSECT PROTEINS; MORPHOGENESIS;

EID: 0032005387     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-1878(199802)20:2<116::AID-BIES4>3.0.CO;2-R     Document Type: Review

References (81)

1. Botas, J. (1993) Control of morphogenesis and differentiation by HOM/ Hox genes. Curr Opm Cell Biol 5:1015-1022.
2. McGinnis, W. and Krumlauf, R. (1992) Homeobox genes and axial patterning. Cell 68:283-302.
3. Muragaki, Y., Mundlos, S., Upton, J. and Olsen, B.R. (1996) Altered growth and branching patterns in synpolydactyly caused by mutations in HOXD13. Science 272:548-551.
4. Mortlock, D.P., Post, L.C. and Innis J.W. (1996) The molecular basis of hypodactyly (Hd): A deletion in Hoxa13 leads to arrest of digital arch formation. Nature Gene 13:284-289.
5. Mann, R.S. (1994) engrailed-mediated repression of Ultrabithorax is necessary for the parasegment 6 identity in Drosophila. Development 120: 3205-3212.
6. Castelli-Gair, J., Greig, S., Micklem, G. and Akam, M. (1994) Dissecting the temporal requirements for homeotic gene function. Development 120:1983-1995.
7. Castelli-Gair, J. and Akam M. (1995) How the Hox gene Ultrabithorax specifies two different segments: The significance of spatial and temporal regulation within metameres. Development 121:2973-2982.
8. Salser, S. and Kenyon C. (1996) A C. elegans Hox gene switches on, off, on and off again to regulate proliferation, differentiation and morphogenesis. Development 122:1651-1661.
9. Eresh, S., Riese, J., Jackson, D.B., Bohmann, D. and Bienz, M. (1997) A CREB-binding site as a target for decapentaplegic signalling during Drosophila endoderm induction. EMBO J 16:2014-2022.
10. Riese, J., Yu, X., Munnerlyn, A., Eresh, S., Hsu, S.C., Grosschedl, R. and Bienz, M. (1997) LEF-1, a nuclear factor coordinating signalling inputs from wingless and decapentaplegic. Cell 88:777-787.
11. Small, S., Kraut, R., Hoey, T., Warrior, R. and Levine M. (1991) Transcriptional regulation of a pair-rule stripe in Drosophila. Genes Dev 5:827-839.
12. Qian, S., Capovilla, M. and Pirrotta, V. (1993) Molecular mechanisms of pattern formation by the BRE enhancer of the Ubx gene. EMBO J 12:3865-3877.
13. Shimell, M., Simon, J., Bender, W. and O'Connor, M. (1994) Enhancer point mutation results in a homeotic transformation in Drosophila. Science 264:968-971.
14. Patel, N. (1994) The evolution of arthropod segmentation: Insights from comparisons of gene expression patterns. Development suppl: 201-207.
15. Sommer, R.J. and Tautz, D. (1993) Involvement of an orthologue of the Drosophila pair rule gene hairy in segment formation of the short germ band embryo of Tribolium(Coleoptera). Nature 361:448-450.
16. Wolff, C., Sommer, R., Schroder, R., Glaser, G. and Tautz, D. (1995) Conserved and divergent expression aspects of the Drosophila segmentation gene hunchback in the short germ band embryo of the flour beetle Tribolium. Development 121:4227-4236.
17. Brown, S. and Denell, R. (1996) Segmentation and dorsoventral patterning in Tribolium. Cell Dev Biol 7:553-560.
18. Sulston, I. and Anderson, K. (1996) Genetic analysis of embryonic patterning mechanisms in the beetle Tribolium castaneum. Cell Dev Biol 7:561-571.
19. Cowing, D. and Kenyon, C. (1996) Correct Hox gene expression established independently of position in Caenorhabditis elegans. Nature 382:353-356
20. Nardelli-Haefliger, D., Bruce, A.E.E. and Shankland, M. (1994) An axial domain of HOM/Hox gene expression is formed by morphogenetic alignment of independently specified cell lineages in the leech Helobdella. Development 120:1839-1849.
21. Sham, M.H. (1993) The zinc linger gene Krox20 regulates HoxB2 (Hox2.8) during hindbram segmentation. Cell 72:183-196.
22. Manzanares, M., Cordes, S., Kwan, C.T., Sham, M.H., Barsh, G.S. and Krumlauf, R. (1997) Segmental regulation of Hoxb-3 by kreisler. Nature 387: 191-195.
23. Boncinelli, E., Simeone, A., Acampora, D. and Mavilio, F. (1991) Hox gene activation by retinoic acid. Trends Gene 7:329-334.
24. Krumlauf, R. (1994) Hox genes in vertebrate development. Cell 78:191-201.
25. Marshall, H., Nonchev, S., Sham, M.A., Muchamore, I., Lumsden, A. and Krumlauf R. (1992) Retinoic acid alters hindbrain Hox code and induces transformation of rhombomeres 2/3 into a 4/5 identity. Nature 360:737-741.
26. Marshall, H., Studer, M., Popperl, H., Aparicio, S., Kurolwa, A., Brenner, S. and Krumlauf, R. (1994) A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1. Nature 370:567-571.
27. Lewis, E.B. (1964) Genetic control and regulation of developmental pathways. In The Chromosomes in Development, (ed. M. Loke) Academic Press, New York.
28. Hoppler, S. and Bienz, M. (1994) Specification of a single cell type by a Drosophila homeotic gene. Cell 76:689-702.
29. Lewis, E.B. (1978) A gene complex controlling segmentation in Drosophila. Nature 276:565-570.
30. Struhl, G. and Akam, M. (1985) Altered distributions of Ultrabithorax transcripts in extra sex combs mutant embryos of Drosophila. EMBO J 4:3259-3264.
31. Wedeen, C., Harding, K. and Levine, M. (1986) Spatial regulation of Antennapedia and bithorax gene expression by the Polycomb locus in Drosophila. Cell 44:739-748.
32. Simon, J. (1995) Locking in stable states of gene expression: Transcriptional control during Drosophila development. Curr Opin Cell Biol 7:376-385.
33. Chan, C.S., Rastelli, L. and Pirrotta, V. (1994) A Polycomb response element in the Ubx gene that determines an epigenetically inherited state of repression. EMBO J 13:2553-2564.
34. Chang, Y.L., King, B., O'Conner, M., Mazo, A. and Huang, D.H. (1995) Functional reconstruction of frans regulation of the Ultrabithorax promoter by the products of two antagonistic genes, trithorax and Polycomb. Mol Cell Biol 15:6601-6612.
35. Shearn, A. (1989) The ash-1, ash-2, and trx genes of Drosophila melanogaster are functionally related. Genetics 121:517-525.
36. Kennison, J.A. (1993) Transcriptional activation of Drosophila homeotic genes from distant regulatory elements. Trends Gene 9:75-79.
37. Breen, T.R. and Harte P.J. (1993) trithorax regulates multiple homeotic genes in the bithorax and Antennapedia complexes and exerts different tissue-specific, parasegment-specific and promoter-specific effects on each. Development 117:119-134.
38. Tamkun, J.W., Deuring, R., Scott, M.P., Kissinger, M., Pattatucci, A.M., Kaufman, T.C., and Kennison J.A. (1992) brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2. Cell 68:561-572.
39. Pazin, M.J. and Kadonaga J.T. (1997) SWI2/SNF2 and related proteins: ATP-driven motors that disrupt Protein-DNA interactions? Cell 88:737-740.
40. Biggin, M.D. and Tijan R. (1988) Transcription factors that activate the Ultrabithorax promoter in developmentally staged extracts. Cell 53:699-711.
41. Farkas, G., Gausz, J., Galloni, M., Reuters, G., Gyurkovics, H. and Karch F. (1994) The Trithorax-like gene encodes the Drosophila GAGA factor Nature 371:806-808.
42. Tsukiyama, T. and Wu C. (1995) Purification and properties of an ATP-dependent nucleosome remodeling factor. Cell 83:1011-1020.
43. Muller, J., Gaunt, S. and Lawrence P. (1995) Function of the Polycomb protein is conserved in mice and flies. Development 121:2847-2852.
44. Goodrich, J., Puangsomlee, P., Martin, M., Long, D., Meyerowitz, E.M. and Coupland G. (1997) A Polycomb-group gene regulates homeotic gene expression in Arabidopsis. Nature 386:44-51.
45. Regulski, M., Dessain, S., McGinnis, N. and McGinnis W. (1991) High-affinity binding sites for the Deformed protein are required for the function of an autoregulatory enhancer of the Deformed gene. Genes Dev 5:278-286.
46. Chouinard, S. and Kaufman T.C. (1991) Control of expression of the homeotic labial (lab) locus of Drosophila melanogaster: evidence for both positive and negative autogenous regulation. Development 113:1267-1280.
47. Chan, S.K., Popperl, H., Krumlauf, R. and Mann, R.S. (1996) An extradenticle-induced conformational change in a HOX protein overcomes an inhibitory function of the conserved hexapeptide motif. EMBO J 15:2476-2487.
48. Popperl, H., Bienz, M., Studer, M., Chan, S., Aparicio, S., Brenner, S., Mann, R.S. and Krumlauf, R. (1995) Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx. Cell 81:1031-1042.
49. Gould, A., Morrison, A., Sproat, G., White, R.A.H. and Krumlauf, R. (1997) Positive cross-regulation and enhancer sharing: two mechanisms for specifying overlapping Hox expression patterns. Genes Dev 11:900-913.
50. Malicki, J., Cianetti, J., Peschle, C.L. and McGinnis, W. (1992) A human HOX4B regulatory element provides head-specific expression in Drosophila embryos. Nature 358:345-347.
51. Awgulewitsch, A. and Jacobs, D. (1992) The Deformed autoregulatory element functions in a conserved manner in transgenic mice. Nature 358:341-344.
52. Pinsonneault, J., Florence, B., Vaessin, H. and McGinnis, W. (1997) A model for extradenticle function as a switch that changes Hox proteins from repressors to activators. EMBO J 16:2032-2042.
53. van Dijk, M. and Murre, C. (1994) extradenticle raises the DNA binding specificity of homeotic selector gene products. Cell 78:617-624.
54. Bienz, M. (1994) Homeotic genes and positional signalling in the Drosophila viscera. Trends Gene 10:22-26.
55. Appel, B. and Sakonju, S. (1993) Cell-type-specific mechanisms of transcriptional repression by the homeotic gene products UBX and ABD-A in Drosophila embryos. EMBO J 12:1099-1109.
56. Peifer, M. and Wieschaus, E. (1990) Mutations in the Drosophila gene extradenticle affect the way specific homeo domain proteins regulate segmental identity. Genes Dev 4:1209-1223.
57. Reuter, R. and Scott, M.P. (1990) Expression and function of the homeotic genes Antennapedia and Sex combs reduced in the embryonic midgut of Drosophila. Development 109:289-303.
58. Celniker, S.E., Sharma, S., Keelan, D.J. and Lewis, E.B. (1990) The molecular genetics of the bithorax complex of Drosophila: cis-regulation of the Abdominal-B domain. EMBO J 9:4277-4286
59. Gerard, M., Chen, J.Y., Gronemeyer, H., Chambon, P., Duboule, D. and Zakany, J. (1996) In vivo targeted mutagenesis of a regulatory element required for positioning the Hoxd-11 and Hoxd-10 expression boundaries. Genes Dev 10:2326-2334.
60. Gyurkovics, H., Gausz, J., Kummer, J. and Karch, F. (1990) A new homeotic mutation in the Drosophila bithorax complex removes a boundary separating two domains of regulation. EMBO J 9:2579-2585.
61. Zhou, J., Barolo, S., Szymanski, P. and Levine, M. (1996) The Fab-7 element of the bithorax complex attenuates enhancer-promoter interactions in the Drosophila embryo. Genes Dev 10:3195-3201.
62. Hagstrom, K., Muller, M. and Schedl, P. (1996) Fab-7 functions as a chromatin domain boundary to ensure proper segment specification by the Drosophila bithorax complex. Genes Dev 10:302-3215.
63. Karch, F., Weiffenbach, B., Bender, W., Peifer, M., Duncan, I., Celneken, S., Crosby, M. and Lewis, E.B. (1985) The abdominal region of the Bithorax complex. Cell 43:81-96.
64. Galloni, M., Gyurkovics, H., Schedl, P. and Karch, F. (1993) The bluetail transposon: evidence for independent cis-regulatory domains and domain boundaries in the bithorax complex. EMBO J 12:1087-1097.
65. Denell, R.E., Brown, S.J. and Beeman, R.W. (1996) Evolution of the organization and function of insect homeotic complexes. Cell Dev Biol 7:527-538.
66. Warren, R.W., Nagy, I., Selegue, J., Gates, J. and S. Carroll (1994) Evolution of homeotic gene regulation and function in flies and butterflies. Nature 372:458-461.
67. Rogers, B.T., Peterson, M.D. and Kaufman, T.C. (1997) Evolution of the insect body plan as revealed by the Sex combs reduced expression pattern. Development 124:149-1557.
68. Kaufman, T.C., Seeger, M.A. and Olsen, G. (1990) Molecular and genetic organization of the Antennapedia gene complex of Drosophila melanogaster. in Advances in Genetics. Genetic Regulatory Hierarchies in Development. 27:309-362.
69. Averof, M. and Akam, M. (1995) Hox genes and the diversification of insect and crustacean body plans. Nature 376:420-423.
70. Gould, S.J. (1991): The disparity of the Burgess Shale arthropod fauna and the imits of cladistic analysis: why we must strive to quantify morphospace. Paleobiology 17:411-423.
71. Burke, A.C., Nelson, C.E., Morgand, B.A. and Tabin, C. (1995) Hox genes and the evolution of vertebrate axial morphology. Development 121:333-346.
72. Li, X. and Noll, M. (1994) Evolution of distinct developmental functions of three Drosophila genes by acquisition of different cis-regulatory regions. Nature 367:83-87.
73. Carroll, S., Weatherbee, S., Langeland, J. (1995) Homeotic genes and the regulation and evolution of insect wing number. Nature 375:58-61.
74. Hinz, U., Wolk, A. and Renkawitz-Pohl, R. (1992): Ultrabithorax is a regulator of b3 tubulin expression in the Drosophila visceral mesoderm. Development 116:543-554.
75. Thuringer, F., Cohen, S.M. and Bienz, M. (1993) Dissection of an indirect autoregulatory response of a homeotic Drosophila gene. EMBO J 12:2419-2430.
76. Zeng, C., Pinsonneault, J., Gellon, G., McGinnis, N. and McGinnis, W. (1994) Deformed protein binding sites and cofactor binding sites are required for the function of a small segment-specific regulatory element in Drosophila embryos. EMBO J 13 No. 10:2362-2377.
77. Lou, L., Bergson, C. and McGinnis, W. (1995) Deformed expression in the Drosophila central nervous system is controlled by an autoactivated intronic enhancer. Nucl Acids Res 23:3481-3487.
78. Averof, M. and Akam, M. (1993) HOM/Hox genes of Artemia: implications for the origin of insect and crustacean body plans. Curr Biol 3:73-78.
79. Holland, P.W., Garcia-Fernandez, J., Williams, N.A. and Sidow, A. (1994) Gene duplications and the origins of vertebrate development. Development Suppl: 125-133.
80. Averof, M., Dawes, R. and Ferrier, D. (1996): Diversification of arthropod Hox genes as a paradigm for the evolution of gene functions. Cell Dev Biol 7:539-551.
81. Whittington, N.B. (1985) The Burgess Shale. Yale University Press. New Haven, CT.