-
1
-
-
0032575688
-
The Bcl-2 protein family: arbiters of cell survival
-
Adams J.M., and Cory S. The Bcl-2 protein family: arbiters of cell survival. Science 281 (1998) 1322-1326
-
(1998)
Science
, vol.281
, pp. 1322-1326
-
-
Adams, J.M.1
Cory, S.2
-
2
-
-
0031036896
-
Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease
-
Anglade P., Vyas S., Javoy-Agid F., et al. Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease. Histol Histopathol 12 (1997) 25-31
-
(1997)
Histol Histopathol
, vol.12
, pp. 25-31
-
-
Anglade, P.1
Vyas, S.2
Javoy-Agid, F.3
-
3
-
-
0032575714
-
Death receptors: signaling and modulation
-
Ashkenazi A., and Dixit V.M. Death receptors: signaling and modulation. Science 281 (1998) 1305-1308
-
(1998)
Science
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
4
-
-
0024677597
-
Trophic factors and neuronal survival
-
Barde Y.A. Trophic factors and neuronal survival. Neuron 2 (1989) 1525-1534
-
(1989)
Neuron
, vol.2
, pp. 1525-1534
-
-
Barde, Y.A.1
-
5
-
-
0032979438
-
Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation
-
Behrens A., Sibilia M., and Wagner E.F. Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation. Nat Genet 21 (1999) 326-329
-
(1999)
Nat Genet
, vol.21
, pp. 326-329
-
-
Behrens, A.1
Sibilia, M.2
Wagner, E.F.3
-
7
-
-
0028364696
-
Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease
-
Boka G., Anglade P., Wallach D., et al. Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease. Neurosci Lett 172 (1994) 151-154
-
(1994)
Neurosci Lett
, vol.172
, pp. 151-154
-
-
Boka, G.1
Anglade, P.2
Wallach, D.3
-
8
-
-
5444274362
-
Ontogenic cell death in the nigrostriatal system
-
Burke R.E. Ontogenic cell death in the nigrostriatal system. Cell Tissue Res 318 (2004) 63-72
-
(2004)
Cell Tissue Res
, vol.318
, pp. 63-72
-
-
Burke, R.E.1
-
9
-
-
0034710649
-
Structural and biochemical basis of apoptotic activation by Smac/DIABLO
-
Chai J., Du C., Wu J.W., et al. Structural and biochemical basis of apoptotic activation by Smac/DIABLO. Nature 406 (2000) 855-862
-
(2000)
Nature
, vol.406
, pp. 855-862
-
-
Chai, J.1
Du, C.2
Wu, J.W.3
-
10
-
-
0032535483
-
The ubiquitin-proteasome pathway: on protein death and cell life
-
Ciechanover A. The ubiquitin-proteasome pathway: on protein death and cell life. EMBO J 17 (1998) 7151-7160
-
(1998)
EMBO J
, vol.17
, pp. 7151-7160
-
-
Ciechanover, A.1
-
11
-
-
0021934489
-
Neuronal death in the development of the vertebrate nervous system
-
Clarke P.G.H. Neuronal death in the development of the vertebrate nervous system. Trends Neurosci 8 (1985) 345-349
-
(1985)
Trends Neurosci
, vol.8
, pp. 345-349
-
-
Clarke, P.G.H.1
-
12
-
-
0025283961
-
Developmental cell death: morphological diversity and multiple mechanisms
-
Clarke P.G.H. Developmental cell death: morphological diversity and multiple mechanisms. Anat Embryol 181 (1990) 195-213
-
(1990)
Anat Embryol
, vol.181
, pp. 195-213
-
-
Clarke, P.G.H.1
-
13
-
-
0035818540
-
c-Jun mediates axotomy-induced dopamine neuron death in vivo
-
Crocker S.J., Lamba W.R., Smith P.D., et al. c-Jun mediates axotomy-induced dopamine neuron death in vivo. Proc Natl Acad Sci USA 98 (2001) 13385-13390
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 13385-13390
-
-
Crocker, S.J.1
Lamba, W.R.2
Smith, P.D.3
-
14
-
-
0016139538
-
Mass fragmentography of dopamine and 6-hydroxydopamine. Application to the determination of dopamine in human brain biopsies from the caudate nucleus
-
Curtius H.C., Wolfensberger M., Steinmann B., et al. Mass fragmentography of dopamine and 6-hydroxydopamine. Application to the determination of dopamine in human brain biopsies from the caudate nucleus. J Chromatogr 99 (1974) 529-540
-
(1974)
J Chromatogr
, vol.99
, pp. 529-540
-
-
Curtius, H.C.1
Wolfensberger, M.2
Steinmann, B.3
-
15
-
-
0033635235
-
14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation
-
Datta S.R., Katsov A., Hu L., et al. 14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation. Mol Cell 6 (2000) 41-51
-
(2000)
Mol Cell
, vol.6
, pp. 41-51
-
-
Datta, S.R.1
Katsov, A.2
Hu, L.3
-
16
-
-
0035153212
-
Immune function of astrocytes
-
Dong Y., and Benveniste E.N. Immune function of astrocytes. Glia 36 (2001) 180-190
-
(2001)
Glia
, vol.36
, pp. 180-190
-
-
Dong, Y.1
Benveniste, E.N.2
-
17
-
-
0037174934
-
JNK phosphorylation and activation of BAD couples the stress-activated signaling pathway to the cell death machinery
-
Donovan N., Becker E.B., Konishi Y., et al. JNK phosphorylation and activation of BAD couples the stress-activated signaling pathway to the cell death machinery. J Biol Chem 277 (2002) 40944-40949
-
(2002)
J Biol Chem
, vol.277
, pp. 40944-40949
-
-
Donovan, N.1
Becker, E.B.2
Konishi, Y.3
-
19
-
-
0000608944
-
Ueber Untergang von Zellen wahrend der normalen Entwicklung bei Wirbeltieren
-
Ernst M. Ueber Untergang von Zellen wahrend der normalen Entwicklung bei Wirbeltieren. Zeitschr Anat u Entw gesch 79 (1926) 228-262
-
(1926)
Zeitschr Anat u Entw gesch
, vol.79
, pp. 228-262
-
-
Ernst, M.1
-
20
-
-
2542475349
-
Genetic ablation of tumor necrosis factor-alpha (TNF-alpha) and pharmacological inhibition of TNF-synthesis attenuates MPTP toxicity in mouse striatum
-
Ferger B., Leng A., Mura A., et al. Genetic ablation of tumor necrosis factor-alpha (TNF-alpha) and pharmacological inhibition of TNF-synthesis attenuates MPTP toxicity in mouse striatum. J Neurochem 89 (2004) 822-833
-
(2004)
J Neurochem
, vol.89
, pp. 822-833
-
-
Ferger, B.1
Leng, A.2
Mura, A.3
-
21
-
-
0029992798
-
Selective c-Jun overexpression is associated with ionizing radiation-induced apoptosis in the developing cerebellum of the rat
-
Ferrer I., Olive M., Blanco R., et al. Selective c-Jun overexpression is associated with ionizing radiation-induced apoptosis in the developing cerebellum of the rat. Mol Br Res 38 (1996) 91-100
-
(1996)
Mol Br Res
, vol.38
, pp. 91-100
-
-
Ferrer, I.1
Olive, M.2
Blanco, R.3
-
22
-
-
0029967179
-
Naturally occurring (programmed) and radiation-induced apoptosis are associated with selective c-jun expression in the developing rat brain
-
Ferrer I., Olive M., Ribera J., et al. Naturally occurring (programmed) and radiation-induced apoptosis are associated with selective c-jun expression in the developing rat brain. Eur J Neurosci 8 (1996) 1286-1298
-
(1996)
Eur J Neurosci
, vol.8
, pp. 1286-1298
-
-
Ferrer, I.1
Olive, M.2
Ribera, J.3
-
24
-
-
1442275733
-
Caspase-11 mediates inflammatory dopaminergic cell death in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
-
Furuya T., Hayakawa H., Yamada M., et al. Caspase-11 mediates inflammatory dopaminergic cell death in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. J Neurosci 24 (2004) 1865-1872
-
(2004)
J Neurosci
, vol.24
, pp. 1865-1872
-
-
Furuya, T.1
Hayakawa, H.2
Yamada, M.3
-
25
-
-
0347717690
-
CEP11004, a novel inhibitor of the mixed lineage kinases, suppresses apoptotic death in dopamine neurons of the substantia nigra induced by 6-hydroxydopamine
-
Ganguly A., Oo T.F., Rzhetskaya M., et al. CEP11004, a novel inhibitor of the mixed lineage kinases, suppresses apoptotic death in dopamine neurons of the substantia nigra induced by 6-hydroxydopamine. J Neurochem 88 (2004) 469-480
-
(2004)
J Neurochem
, vol.88
, pp. 469-480
-
-
Ganguly, A.1
Oo, T.F.2
Rzhetskaya, M.3
-
26
-
-
0026648674
-
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
-
Gavrieli Y., Sherman Y., and Ben-Sasson S.A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119 (1992) 493-501
-
(1992)
J Cell Biol
, vol.119
, pp. 493-501
-
-
Gavrieli, Y.1
Sherman, Y.2
Ben-Sasson, S.A.3
-
27
-
-
84915943405
-
Cell deaths in normal vertebrate ontogeny
-
Glucksmann A. Cell deaths in normal vertebrate ontogeny. Biol Rev 26 (1951) 59-86
-
(1951)
Biol Rev
, vol.26
, pp. 59-86
-
-
Glucksmann, A.1
-
28
-
-
0029294613
-
In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note
-
Grasl-Kraupp B., Ruttkay-Nedecky B., Koudelka H., et al. In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note. Hepatology 21 (1995) 1465-1468
-
(1995)
Hepatology
, vol.21
, pp. 1465-1468
-
-
Grasl-Kraupp, B.1
Ruttkay-Nedecky, B.2
Koudelka, H.3
-
29
-
-
0026952803
-
History of the discovery of neuronal death in embryos
-
Hamburger V. History of the discovery of neuronal death in embryos. J Neurobiol 23 (1992) 1116-1123
-
(1992)
J Neurobiol
, vol.23
, pp. 1116-1123
-
-
Hamburger, V.1
-
30
-
-
78651025304
-
Proliferation, differentiation and degeneration in the spinal ganglia of the chick embryo under normal and experimental conditions
-
Hamburger V., and Levi-Montalcini R. Proliferation, differentiation and degeneration in the spinal ganglia of the chick embryo under normal and experimental conditions. J Exp Zool 111 (1949) 457-502
-
(1949)
J Exp Zool
, vol.111
, pp. 457-502
-
-
Hamburger, V.1
Levi-Montalcini, R.2
-
31
-
-
12944250987
-
Caspase-3: a vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease
-
Hartmann A., Hunot S., Michel P.P., et al. Caspase-3: a vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease. Proc Natl Acad Sci USA 97 (2000) 2875-2880
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 2875-2880
-
-
Hartmann, A.1
Hunot, S.2
Michel, P.P.3
-
32
-
-
0035103294
-
Is Bax a mitochondrial mediator in apoptotic death of dopaminergic neurons in Parkinson's disease?
-
Hartmann A., Michel P.P., and Troadec J.D. Is Bax a mitochondrial mediator in apoptotic death of dopaminergic neurons in Parkinson's disease?. J Neurochem 76 (2001) 1785-1793
-
(2001)
J Neurochem
, vol.76
, pp. 1785-1793
-
-
Hartmann, A.1
Michel, P.P.2
Troadec, J.D.3
-
33
-
-
0035313071
-
Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis
-
Hartmann A., Troadec J.D., Hunot S., et al. Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis. J Neurosci 21 (2001) 2247-2255
-
(2001)
J Neurosci
, vol.21
, pp. 2247-2255
-
-
Hartmann, A.1
Troadec, J.D.2
Hunot, S.3
-
34
-
-
0037154136
-
FADD: a link between TNF family receptors and caspases in Parkinson's disease
-
Hartmann A., Mouatt-Prigent A., Faucheux B.A., et al. FADD: a link between TNF family receptors and caspases in Parkinson's disease. Neurology 58 (2002) 308-310
-
(2002)
Neurology
, vol.58
, pp. 308-310
-
-
Hartmann, A.1
Mouatt-Prigent, A.2
Faucheux, B.A.3
-
35
-
-
0029670980
-
Increase in bax expression in substantia-nigra following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treatment of mice
-
Hassouna I., Wickert H., Zimmermann M., et al. Increase in bax expression in substantia-nigra following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treatment of mice. Neurosci Lett 204 (1996) 85-88
-
(1996)
Neurosci Lett
, vol.204
, pp. 85-88
-
-
Hassouna, I.1
Wickert, H.2
Zimmermann, M.3
-
36
-
-
10744223673
-
Regulation of dopaminergic loss by Fas in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease
-
Hayley S., Crocker S.J., Smith P.D., et al. Regulation of dopaminergic loss by Fas in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. J Neurosci 24 (2004) 2045-2053
-
(2004)
J Neurosci
, vol.24
, pp. 2045-2053
-
-
Hayley, S.1
Crocker, S.J.2
Smith, P.D.3
-
37
-
-
0033955925
-
6-Hydroxydopamine induced apoptosis of dopaminergic cells in the rat substantia nigra
-
He Y., Lee T., and Leong S.K. 6-Hydroxydopamine induced apoptosis of dopaminergic cells in the rat substantia nigra. Brain Res 858 (2000) 163-166
-
(2000)
Brain Res
, vol.858
, pp. 163-166
-
-
He, Y.1
Lee, T.2
Leong, S.K.3
-
38
-
-
0028288277
-
C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2
-
Hengartner M.O., and Horvitz H.R. C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2. Cell 76 (1994) 665-676
-
(1994)
Cell
, vol.76
, pp. 665-676
-
-
Hengartner, M.O.1
Horvitz, H.R.2
-
39
-
-
0032527879
-
Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinases after neuronal injury
-
Herdegen T., Claret F.X., Kallunki T., et al. Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinases after neuronal injury. J Neurosci 18 (1998) 5124-5135
-
(1998)
J Neurosci
, vol.18
, pp. 5124-5135
-
-
Herdegen, T.1
Claret, F.X.2
Kallunki, T.3
-
40
-
-
2442432416
-
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death
-
Hitomi J., Katayama T., Eguchi Y., et al. Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death. J Cell Biol 165 (2004) 347-356
-
(2004)
J Cell Biol
, vol.165
, pp. 347-356
-
-
Hitomi, J.1
Katayama, T.2
Eguchi, Y.3
-
41
-
-
0038143287
-
Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons
-
Holtz W.A., and O'Malley K.L. Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons. J Biol Chem 278 (2003) 19367-19377
-
(2003)
J Biol Chem
, vol.278
, pp. 19367-19377
-
-
Holtz, W.A.1
O'Malley, K.L.2
-
42
-
-
0346374790
-
JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease
-
Hunot S., Vila M., Teismann P., et al. JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease. Proc Natl Acad Sci USA 101 (2004) 665-670
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 665-670
-
-
Hunot, S.1
Vila, M.2
Teismann, P.3
-
43
-
-
0034680913
-
Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity
-
Imai Y., Soda M., and Takahashi R. Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity. J Biol Chem 275 (2000) 35661-35664
-
(2000)
J Biol Chem
, vol.275
, pp. 35661-35664
-
-
Imai, Y.1
Soda, M.2
Takahashi, R.3
-
44
-
-
0035967883
-
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin
-
Imai Y., Soda M., Inoue H., et al. An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. Cell 105 (2001) 891-902
-
(2001)
Cell
, vol.105
, pp. 891-902
-
-
Imai, Y.1
Soda, M.2
Inoue, H.3
-
45
-
-
0030015934
-
Clinical analysis of 17 patients in 12 Japanese families with autosomal-recessive type juvenile parkinsonism
-
Ishikawa A., and Tsuji S. Clinical analysis of 17 patients in 12 Japanese families with autosomal-recessive type juvenile parkinsonism. Neurology 47 (1996) 160-166
-
(1996)
Neurology
, vol.47
, pp. 160-166
-
-
Ishikawa, A.1
Tsuji, S.2
-
46
-
-
0028784523
-
Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
-
Jackson-Lewis V., Jakowec M., Burke R.E., et al. Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Neurodegeneration 4 (1995) 257-269
-
(1995)
Neurodegeneration
, vol.4
, pp. 257-269
-
-
Jackson-Lewis, V.1
Jakowec, M.2
Burke, R.E.3
-
47
-
-
0034726658
-
Developmental cell death in dopaminergic neurons of the substantia nigra of mice
-
Jackson-Lewis V., Vila M., Djaldetti R., et al. Developmental cell death in dopaminergic neurons of the substantia nigra of mice. J Comp Neurol 424 (2000) 476-488
-
(2000)
J Comp Neurol
, vol.424
, pp. 476-488
-
-
Jackson-Lewis, V.1
Vila, M.2
Djaldetti, R.3
-
48
-
-
0027407590
-
Naturally occurring cell death during postnatal development of the substantia nigra of the rat
-
Janec E., and Burke R.E. Naturally occurring cell death during postnatal development of the substantia nigra of the rat. Mol Cell Neurosci 4 (1993) 30-35
-
(1993)
Mol Cell Neurosci
, vol.4
, pp. 30-35
-
-
Janec, E.1
Burke, R.E.2
-
49
-
-
0025826445
-
Long-term increase in the levels of c-jun mRNA and jun protein-like immunoreactivity in motor and sensory neurons following axon damage
-
Jenkins R., and Hunt S.P. Long-term increase in the levels of c-jun mRNA and jun protein-like immunoreactivity in motor and sensory neurons following axon damage. Neurosci Lett 129 (1991) 107-110
-
(1991)
Neurosci Lett
, vol.129
, pp. 107-110
-
-
Jenkins, R.1
Hunt, S.P.2
-
50
-
-
0027416834
-
c-jun expression in substantia nigra neurons following striatal 6-hydroxydopamine lesions in the rat
-
Jenkins R., O'Shea R., Thomas K.L., et al. c-jun expression in substantia nigra neurons following striatal 6-hydroxydopamine lesions in the rat. Neuroscience 53 (1993) 447-455
-
(1993)
Neuroscience
, vol.53
, pp. 447-455
-
-
Jenkins, R.1
O'Shea, R.2
Thomas, K.L.3
-
51
-
-
0029018424
-
6-Hydroxydopamine lesion of the rat substantia nigra: time course and morphology of cell death
-
Jeon B.S., Jackson-Lewis V., and Burke R.E. 6-Hydroxydopamine lesion of the rat substantia nigra: time course and morphology of cell death. Neurodegeneration 4 (1995) 131-137
-
(1995)
Neurodegeneration
, vol.4
, pp. 131-137
-
-
Jeon, B.S.1
Jackson-Lewis, V.2
Burke, R.E.3
-
52
-
-
0032995961
-
Activation of caspase-3 in developmental models of programmed cell death in neurons of the substantia nigra
-
Jeon B.S., Kholodilov N.G., Oo T.F., et al. Activation of caspase-3 in developmental models of programmed cell death in neurons of the substantia nigra. J Neurochem 73 (1999) 322-333
-
(1999)
J Neurochem
, vol.73
, pp. 322-333
-
-
Jeon, B.S.1
Kholodilov, N.G.2
Oo, T.F.3
-
53
-
-
0027717968
-
Bcl 2 inhibition of neural death: decreased generation of reactive oxygen species
-
Kane D.J., Sarafian T.A., Anton R., et al. Bcl 2 inhibition of neural death: decreased generation of reactive oxygen species. Science 262 (1993) 1274-1277
-
(1993)
Science
, vol.262
, pp. 1274-1277
-
-
Kane, D.J.1
Sarafian, T.A.2
Anton, R.3
-
54
-
-
77956801270
-
Anatomical methods in cell death
-
Schwartz L.M., and Osborne B.A. (Eds), Academic Press, New York
-
Kerr J.F.R., Gobe G.C., Winterford C.M., et al. Anatomical methods in cell death. In: Schwartz L.M., and Osborne B.A. (Eds). Methods in Cell Biology: Cell Death (1995), Academic Press, New York 1-27
-
(1995)
Methods in Cell Biology: Cell Death
, pp. 1-27
-
-
Kerr, J.F.R.1
Gobe, G.C.2
Winterford, C.M.3
-
55
-
-
0015383455
-
Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr J.F.R., Wyllie A.H., and Currie A.R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26 (1972) 239-257
-
(1972)
Br J Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.R.1
Wyllie, A.H.2
Currie, A.R.3
-
56
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T., Asakawa S., Hattori N., et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392 (1998) 605-608
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
-
57
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
Klionsky D.J., and Emr S.D. Autophagy as a regulated pathway of cellular degradation. Science 290 (2000) 1717-1721
-
(2000)
Science
, vol.290
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
58
-
-
1842297607
-
On the question of apoptosis in the parkinsonian substantia nigra
-
Kosel S., Egensperger R., von Eitzen U., et al. On the question of apoptosis in the parkinsonian substantia nigra. Acta Neuropath 93 (1997) 105-108
-
(1997)
Acta Neuropath
, vol.93
, pp. 105-108
-
-
Kosel, S.1
Egensperger, R.2
von Eitzen, U.3
-
59
-
-
0016143121
-
Pharmacological actions of 6-hydroxydopamine
-
Kostrzewa R.M., and Jacobowitz D.M. Pharmacological actions of 6-hydroxydopamine. Pharmacol Rev 26 (1974) 199-288
-
(1974)
Pharmacol Rev
, vol.26
, pp. 199-288
-
-
Kostrzewa, R.M.1
Jacobowitz, D.M.2
-
60
-
-
0030820875
-
Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis
-
Kothakota S., Azuma T., Reinhard C., et al. Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis. Science 278 (1997) 294-298
-
(1997)
Science
, vol.278
, pp. 294-298
-
-
Kothakota, S.1
Azuma, T.2
Reinhard, C.3
-
61
-
-
11144245626
-
The role of autophagy during the early neonatal starvation period
-
Kuma A., Hatano M., Matsui M., et al. The role of autophagy during the early neonatal starvation period. Nature 432 (2004) 1032-1036
-
(2004)
Nature
, vol.432
, pp. 1032-1036
-
-
Kuma, A.1
Hatano, M.2
Matsui, M.3
-
62
-
-
0035066383
-
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
-
Kyriakis J.M., and Avruch J. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 81 (2001) 807-869
-
(2001)
Physiol Rev
, vol.81
, pp. 807-869
-
-
Kyriakis, J.M.1
Avruch, J.2
-
63
-
-
0037109770
-
Methamphetamine-induced degeneration of dopaminergic neurons involves autophagy and upregulation of dopamine synthesis
-
Larsen K.E., Fon E.A., Hastings T.G., et al. Methamphetamine-induced degeneration of dopaminergic neurons involves autophagy and upregulation of dopamine synthesis. J Neurosci 22 (2002) 8951-8960
-
(2002)
J Neurosci
, vol.22
, pp. 8951-8960
-
-
Larsen, K.E.1
Fon, E.A.2
Hastings, T.G.3
-
64
-
-
0027428846
-
Expression of immediate early gene proteins following axotomy and inhibition of axonal transport in the rat central nervous system
-
Leah J.D., Herdegen T., Murashov A., et al. Expression of immediate early gene proteins following axotomy and inhibition of axonal transport in the rat central nervous system. Neuroscience 57 (1993) 53-66
-
(1993)
Neuroscience
, vol.57
, pp. 53-66
-
-
Leah, J.D.1
Herdegen, T.2
Murashov, A.3
-
65
-
-
0037418238
-
JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
-
Lei K., and Davis R.J. JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis. Proc Natl Acad Sci USA 100 (2003) 2432-2437
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 2432-2437
-
-
Lei, K.1
Davis, R.J.2
-
66
-
-
0023236055
-
The nerve growth factor 35 years later
-
Levi-Montalcini R. The nerve growth factor 35 years later. Science 237 (1987) 1154-1162
-
(1987)
Science
, vol.237
, pp. 1154-1162
-
-
Levi-Montalcini, R.1
-
67
-
-
12944303650
-
Growth factor regulation of autophagy and cell survival in the absence of apoptosis
-
Lum J.J., Bauer D.E., Kong M., et al. Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell 120 (2005) 237-248
-
(2005)
Cell
, vol.120
, pp. 237-248
-
-
Lum, J.J.1
Bauer, D.E.2
Kong, M.3
-
68
-
-
10644233167
-
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
-
Marciniak S.J., Yun C.Y., Oyadomari S., et al. CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum. Genes Dev 18 (2004) 3066-3077
-
(2004)
Genes Dev
, vol.18
, pp. 3066-3077
-
-
Marciniak, S.J.1
Yun, C.Y.2
Oyadomari, S.3
-
69
-
-
0031027178
-
Early developmental destruction of terminals in the striatal target induces apoptosis in dopamine neurons of the substantia nigra
-
Marti M.J., James C.J., Oo T.F., et al. Early developmental destruction of terminals in the striatal target induces apoptosis in dopamine neurons of the substantia nigra. J Neurosci 17 (1997) 2030-2039
-
(1997)
J Neurosci
, vol.17
, pp. 2030-2039
-
-
Marti, M.J.1
James, C.J.2
Oo, T.F.3
-
70
-
-
0037146877
-
Striatal 6-hydroxydopamine induces apoptosis of nigral neurons in the adult rat
-
Marti M.J., Saura J., Burke R.E., et al. Striatal 6-hydroxydopamine induces apoptosis of nigral neurons in the adult rat. Brain Res 958 (2002) 185-191
-
(2002)
Brain Res
, vol.958
, pp. 185-191
-
-
Marti, M.J.1
Saura, J.2
Burke, R.E.3
-
71
-
-
0023851503
-
Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation
-
Martin D.P., Schmidt R.E., DiStefano P., et al. Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation. J Cell Biol 106 (1988) 829-844
-
(1988)
J Cell Biol
, vol.106
, pp. 829-844
-
-
Martin, D.P.1
Schmidt, R.E.2
DiStefano, P.3
-
72
-
-
0031057656
-
Bcl-2 gene family in the nervous system
-
Merry D.E., and Korsmeyer S.J. Bcl-2 gene family in the nervous system. Annu Rev Neurosci 20 (1997) 245-267
-
(1997)
Annu Rev Neurosci
, vol.20
, pp. 245-267
-
-
Merry, D.E.1
Korsmeyer, S.J.2
-
73
-
-
0029815240
-
Detection of jun but not fos protein during developmental cell death in sympathetic neurons
-
Messina A., Jaworowski A., and Bell C. Detection of jun but not fos protein during developmental cell death in sympathetic neurons. J Comp Neurol 372 (1996) 544-550
-
(1996)
J Comp Neurol
, vol.372
, pp. 544-550
-
-
Messina, A.1
Jaworowski, A.2
Bell, C.3
-
74
-
-
0037401983
-
Role of the Apg12 conjugation system in mammalian autophagy
-
Mizushima N., Yoshimori T., and Ohsumi Y. Role of the Apg12 conjugation system in mammalian autophagy. Int J Biochem Cell Biol 35 (2003) 553-561
-
(2003)
Int J Biochem Cell Biol
, vol.35
, pp. 553-561
-
-
Mizushima, N.1
Yoshimori, T.2
Ohsumi, Y.3
-
75
-
-
0029942337
-
Histochemical detection of apoptosis in Parkinson's Disease
-
Mochizuki H., Goto K., Mori H., et al. Histochemical detection of apoptosis in Parkinson's Disease. J Neurol Sci 137 (1996) 120-123
-
(1996)
J Neurol Sci
, vol.137
, pp. 120-123
-
-
Mochizuki, H.1
Goto, K.2
Mori, H.3
-
76
-
-
0035845532
-
An AAV-derived Apaf-1 dominant negative inhibitor prevents MPTP toxicity as antiapoptotic gene therapy for Parkinson's disease
-
Mochizuki H., Hayakawa H., Migita M., et al. An AAV-derived Apaf-1 dominant negative inhibitor prevents MPTP toxicity as antiapoptotic gene therapy for Parkinson's disease. Proc Natl Acad Sci USA 98 (2001) 10918-10923
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10918-10923
-
-
Mochizuki, H.1
Hayakawa, H.2
Migita, M.3
-
77
-
-
0030595986
-
The soluble form of Fas molecule is elevated in parkinsonian brain tissues
-
Mogi M., Harada M., Kondo T., et al. The soluble form of Fas molecule is elevated in parkinsonian brain tissues. Neurosci Lett 220 (1996) 195-198
-
(1996)
Neurosci Lett
, vol.220
, pp. 195-198
-
-
Mogi, M.1
Harada, M.2
Kondo, T.3
-
78
-
-
0028178281
-
Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients
-
Mogi M., Harada M., Riederer P., et al. Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients. Neurosci Lett 165 (1994) 208-210
-
(1994)
Neurosci Lett
, vol.165
, pp. 208-210
-
-
Mogi, M.1
Harada, M.2
Riederer, P.3
-
79
-
-
4444338911
-
Caspases involved in ER stress-mediated cell death
-
Momoi T. Caspases involved in ER stress-mediated cell death. J Chem Neuroanat 28 (2004) 101-105
-
(2004)
J Chem Neuroanat
, vol.28
, pp. 101-105
-
-
Momoi, T.1
-
80
-
-
0034716887
-
Tripartite management of unfolded proteins in the endoplasmic reticulum
-
Mori K. Tripartite management of unfolded proteins in the endoplasmic reticulum. Cell 101 (2000) 451-454
-
(2000)
Cell
, vol.101
, pp. 451-454
-
-
Mori, K.1
-
81
-
-
18244379883
-
Mixed lineage kinase activity of indolocarbazole analogues
-
Murakata C., Kaneko M., Gessner G., et al. Mixed lineage kinase activity of indolocarbazole analogues. Bioorg Med Chem Lett 12 (2002) 147-150
-
(2002)
Bioorg Med Chem Lett
, vol.12
, pp. 147-150
-
-
Murakata, C.1
Kaneko, M.2
Gessner, G.3
-
82
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
-
Nakagawa T., Zhu H., Morishima N., et al. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 403 (2000) 98-103
-
(2000)
Nature
, vol.403
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
-
83
-
-
0032510758
-
Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity
-
Offen D., Beart P.M., Cheung N.S., et al. Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity. Proc Natl Acad Sci USA 95 (1998) 5789-5794
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 5789-5794
-
-
Offen, D.1
Beart, P.M.2
Cheung, N.S.3
-
84
-
-
0029833389
-
Neuron death in the substantia nigra of weaver mouse occurs late in development and is not apoptotic
-
Oo T.F., Blazeski R., Harrison S.M.W., et al. Neuron death in the substantia nigra of weaver mouse occurs late in development and is not apoptotic. J Neurosci 16 (1996) 6134-6145
-
(1996)
J Neurosci
, vol.16
, pp. 6134-6145
-
-
Oo, T.F.1
Blazeski, R.2
Harrison, S.M.W.3
-
85
-
-
0031579433
-
The time course of developmental cell death in phenotypically defined dopaminergic neurons of the substantia nigra
-
Oo T.F., and Burke R.E. The time course of developmental cell death in phenotypically defined dopaminergic neurons of the substantia nigra. Dev Brain Res 98 (1997) 191-196
-
(1997)
Dev Brain Res
, vol.98
, pp. 191-196
-
-
Oo, T.F.1
Burke, R.E.2
-
86
-
-
0032900219
-
Expression of c-fos, c-jun, and c-jun N-terminal kinase (JNK) in a developmental model of induced apoptotic death in neurons of the substantia nigra
-
Oo T.F., Henchcliffe C., James D., et al. Expression of c-fos, c-jun, and c-jun N-terminal kinase (JNK) in a developmental model of induced apoptotic death in neurons of the substantia nigra. J Neurochem 72 (1999) 557-564
-
(1999)
J Neurochem
, vol.72
, pp. 557-564
-
-
Oo, T.F.1
Henchcliffe, C.2
James, D.3
-
87
-
-
0036254139
-
Distinct nuclear and cytoplasmic localization of caspase cleavage products in two models of induced apoptotic death in dopamine neurons of the substantia nigra
-
Oo T.F., Siman R., and Burke R.E. Distinct nuclear and cytoplasmic localization of caspase cleavage products in two models of induced apoptotic death in dopamine neurons of the substantia nigra. Exp Neurol 175 (2002) 1-9
-
(2002)
Exp Neurol
, vol.175
, pp. 1-9
-
-
Oo, T.F.1
Siman, R.2
Burke, R.E.3
-
88
-
-
0025217864
-
Naturally occurring and induced neuronal death in the chick embryo in vivo requires protein and RNA synthesis: evidence for the role of cell death genes
-
Oppenheim R.W., Prevette D., Tytell M., et al. Naturally occurring and induced neuronal death in the chick embryo in vivo requires protein and RNA synthesis: evidence for the role of cell death genes. Dev Biol 138 (1990) 104-113
-
(1990)
Dev Biol
, vol.138
, pp. 104-113
-
-
Oppenheim, R.W.1
Prevette, D.2
Tytell, M.3
-
89
-
-
1642514774
-
Men are but worms: neuronal cell death in C. elegans and vertebrates
-
Putcha G.V., and Johnson Jr. E.M. Men are but worms: neuronal cell death in C. elegans and vertebrates. Cell Death Differ 11 (2004) 38-48
-
(2004)
Cell Death Differ
, vol.11
, pp. 38-48
-
-
Putcha, G.V.1
Johnson Jr., E.M.2
-
90
-
-
0035053624
-
Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis
-
Putcha G.V., Moulder K.L., Golden J.P., et al. Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis. Neuron 29 (2001) 615-628
-
(2001)
Neuron
, vol.29
, pp. 615-628
-
-
Putcha, G.V.1
Moulder, K.L.2
Golden, J.P.3
-
91
-
-
0035823579
-
Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation
-
Rao R.V., Hermel E., Castro-Obregon S., et al. Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation. J Biol Chem 276 (2001) 33869-33874
-
(2001)
J Biol Chem
, vol.276
, pp. 33869-33874
-
-
Rao, R.V.1
Hermel, E.2
Castro-Obregon, S.3
-
92
-
-
8444220527
-
Molecular mechanisms of caspase regulation during apoptosis
-
Riedl S.J., and Shi Y. Molecular mechanisms of caspase regulation during apoptosis. Nat Rev Mol Cell Biol 5 (2004) 897-907
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 897-907
-
-
Riedl, S.J.1
Shi, Y.2
-
93
-
-
0025939423
-
Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms
-
Rukenstein A., Rydel R.E., and Greene L.A. Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms. J Neurosci 11 (1991) 2552-2563
-
(1991)
J Neurosci
, vol.11
, pp. 2552-2563
-
-
Rukenstein, A.1
Rydel, R.E.2
Greene, L.A.3
-
94
-
-
0037114971
-
Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease
-
Ryu E.J., Harding H.P., Angelastro J.M., et al. Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease. J Neurosci 22 (2002) 10690-10698
-
(2002)
J Neurosci
, vol.22
, pp. 10690-10698
-
-
Ryu, E.J.1
Harding, H.P.2
Angelastro, J.M.3
-
95
-
-
0033029823
-
CEP-1347/KT-7515, an inhibitor of c-jun N-terminal kinase activation, attenuates the 1-methyl-4-phenyl tetrahydropyridine-mediated loss of nigrostriatal dopaminergic neurons in vivo
-
Saporito M.S., Brown E.M., Miller M.S., et al. CEP-1347/KT-7515, an inhibitor of c-jun N-terminal kinase activation, attenuates the 1-methyl-4-phenyl tetrahydropyridine-mediated loss of nigrostriatal dopaminergic neurons in vivo. J Pharmacol Exp Ther 288 (1999) 421-427
-
(1999)
J Pharmacol Exp Ther
, vol.288
, pp. 421-427
-
-
Saporito, M.S.1
Brown, E.M.2
Miller, M.S.3
-
96
-
-
0033840581
-
MPTP activates c-Jun NH(2)-terminal kinase (JNK) and its upstream regulatory kinase MKK4 in nigrostriatal neurons in vivo
-
Saporito M.S., Thomas B.A., and Scott R.W. MPTP activates c-Jun NH(2)-terminal kinase (JNK) and its upstream regulatory kinase MKK4 in nigrostriatal neurons in vivo. J Neurochem 75 (2000) 1200-1208
-
(2000)
J Neurochem
, vol.75
, pp. 1200-1208
-
-
Saporito, M.S.1
Thomas, B.A.2
Scott, R.W.3
-
97
-
-
0028220834
-
Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6 hydroxydopamine a combined retrograde tracing and immunocytochemical study in the rat
-
Sauer H., and Oertel W.H. Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6 hydroxydopamine a combined retrograde tracing and immunocytochemical study in the rat. Neuroscience 59 (1994) 401-415
-
(1994)
Neuroscience
, vol.59
, pp. 401-415
-
-
Sauer, H.1
Oertel, W.H.2
-
98
-
-
0037427412
-
Mechanisms of cytochrome c release by proapoptotic BCL-2 family members
-
Scorrano L., and Korsmeyer S.J. Mechanisms of cytochrome c release by proapoptotic BCL-2 family members. Biochem Biophys Res Commun 304 (2003) 437-444
-
(2003)
Biochem Biophys Res Commun
, vol.304
, pp. 437-444
-
-
Scorrano, L.1
Korsmeyer, S.J.2
-
99
-
-
0036205587
-
Mechanisms of caspase activation and inhibition during apoptosis
-
Shi Y. Mechanisms of caspase activation and inhibition during apoptosis. Mol Cell 9 (2002) 459-470
-
(2002)
Mol Cell
, vol.9
, pp. 459-470
-
-
Shi, Y.1
-
100
-
-
0033933048
-
Familial parkinson disease gene product, parkin, is a ubiquitin-protein ligase
-
Shimura H., Hattori N., Kubo S., et al. Familial parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat Genet 25 (2000) 302-305
-
(2000)
Nat Genet
, vol.25
, pp. 302-305
-
-
Shimura, H.1
Hattori, N.2
Kubo, S.3
-
101
-
-
8344242220
-
Autophagy in health and disease: a double-edged sword
-
Shintani T., and Klionsky D.J. Autophagy in health and disease: a double-edged sword. Science 306 (2004) 990-995
-
(2004)
Science
, vol.306
, pp. 990-995
-
-
Shintani, T.1
Klionsky, D.J.2
-
102
-
-
22844445441
-
Mixed lineage kinase-c-jun N-terminal kinase signaling pathway: a new therapeutic target in Parkinson's disease
-
Silva R.M., Kuan C.Y., Rakic P., et al. Mixed lineage kinase-c-jun N-terminal kinase signaling pathway: a new therapeutic target in Parkinson's disease. Mov Disord 20 6 (2005) 653-664
-
(2005)
Mov Disord
, vol.20
, Issue.6
, pp. 653-664
-
-
Silva, R.M.1
Kuan, C.Y.2
Rakic, P.3
-
103
-
-
28244466782
-
CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism
-
Silva R.M., Ries V., Oo T.F., et al. CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism. J Neurochem 95 4 (2005) 974-986
-
(2005)
J Neurochem
, vol.95
, Issue.4
, pp. 974-986
-
-
Silva, R.M.1
Ries, V.2
Oo, T.F.3
-
105
-
-
0035894855
-
Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death
-
Stefanis L., Larsen K.E., Rideout H.J., et al. Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death. J Neurosci 21 (2001) 9549-9560
-
(2001)
J Neurosci
, vol.21
, pp. 9549-9560
-
-
Stefanis, L.1
Larsen, K.E.2
Rideout, H.J.3
-
107
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
Susin S.A., Lorenzo H.K., Zamzami N., et al. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 397 (1999) 441-446
-
(1999)
Nature
, vol.397
, pp. 441-446
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
-
108
-
-
0033756901
-
Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease
-
Tatton N.A. Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease. Exp Neurol 166 (2000) 29-43
-
(2000)
Exp Neurol
, vol.166
, pp. 29-43
-
-
Tatton, N.A.1
-
109
-
-
0030888286
-
In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange
-
Tatton N.A., and Kish S.J. In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange. Neuroscience 77 (1997) 1037-1048
-
(1997)
Neuroscience
, vol.77
, pp. 1037-1048
-
-
Tatton, N.A.1
Kish, S.J.2
-
110
-
-
0031696403
-
A fluorescent double-labeling method to detect and confirm apoptotic nuclei in Parkinson's disease
-
Tatton N.A., Maclean-Fraser A., Tatton W.G., et al. A fluorescent double-labeling method to detect and confirm apoptotic nuclei in Parkinson's disease. Ann Neurol 44 (1998) S142-S148
-
(1998)
Ann Neurol
, vol.44
-
-
Tatton, N.A.1
Maclean-Fraser, A.2
Tatton, W.G.3
-
111
-
-
0038641723
-
Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration
-
Teismann P., Tieu K., Choi D.K., et al. Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration. Proc Natl Acad Sci USA 100 (2003) 5473-5478
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 5473-5478
-
-
Teismann, P.1
Tieu, K.2
Choi, D.K.3
-
112
-
-
0032575750
-
Caspases: enemies within
-
Thornberry N.A., and Lazebnik Y. Caspases: enemies within. Science 281 (1998) 1312-1316
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebnik, Y.2
-
113
-
-
0031013141
-
Apoptotic-like changes in Lewy-body-associated disorders and normal aging in substantia nigral neurons
-
Tompkins M.M., Basgall E.J., Zamrini E., et al. Apoptotic-like changes in Lewy-body-associated disorders and normal aging in substantia nigral neurons. Am J Path 150 (1997) 119-131
-
(1997)
Am J Path
, vol.150
, pp. 119-131
-
-
Tompkins, M.M.1
Basgall, E.J.2
Zamrini, E.3
-
114
-
-
0035297146
-
Caspase-3 activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice
-
Turmel H., Hartmann A., Parain K., et al. Caspase-3 activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice. Mov Disord 16 (2001) 185-189
-
(2001)
Mov Disord
, vol.16
, pp. 185-189
-
-
Turmel, H.1
Hartmann, A.2
Parain, K.3
-
115
-
-
0014376793
-
6-Hydroxy-dopamine induced degeneration of central monoamine neurons
-
Ungerstedt U. 6-Hydroxy-dopamine induced degeneration of central monoamine neurons. Eur J Pharmacol 5 (1968) 107-110
-
(1968)
Eur J Pharmacol
, vol.5
, pp. 107-110
-
-
Ungerstedt, U.1
-
116
-
-
0023786047
-
Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
-
Vaux D.L., Cory S., and Adams J.M. Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 335 (1988) 440-442
-
(1988)
Nature
, vol.335
, pp. 440-442
-
-
Vaux, D.L.1
Cory, S.2
Adams, J.M.3
-
117
-
-
0027050145
-
Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2
-
Vaux D.L., Weissman I.L., and Kim S.K. Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2. Science 258 (1992) 1955-1957
-
(1992)
Science
, vol.258
, pp. 1955-1957
-
-
Vaux, D.L.1
Weissman, I.L.2
Kim, S.K.3
-
118
-
-
0035956874
-
Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
-
Vila M., Jackson-Lewis V., Vukosavic S., et al. Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. Proc Natl Acad Sci USA 98 (2001) 2837-2842
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 2837-2842
-
-
Vila, M.1
Jackson-Lewis, V.2
Vukosavic, S.3
-
119
-
-
0035894881
-
Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease
-
Viswanath V., Wu Y., Boonplueang R., et al. Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease. J Neurosci 21 (2001) 9519-9528
-
(2001)
J Neurosci
, vol.21
, pp. 9519-9528
-
-
Viswanath, V.1
Wu, Y.2
Boonplueang, R.3
-
120
-
-
1342344813
-
Mixed-lineage kinases: a target for the prevention of neurodegeneration
-
Wang L.H., Besirli C.G., and Johnson Jr. E.M. Mixed-lineage kinases: a target for the prevention of neurodegeneration. Annu Rev Pharmacol Toxicol 44 (2004) 451-474
-
(2004)
Annu Rev Pharmacol Toxicol
, vol.44
, pp. 451-474
-
-
Wang, L.H.1
Besirli, C.G.2
Johnson Jr., E.M.3
-
121
-
-
0035957653
-
Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death
-
Wei M.C., Zong W.X., Cheng E.H., et al. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 292 (2001) 727-730
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
-
122
-
-
0028200532
-
Genetic control of programmed cell death in Drosophila
-
White K., Grether M.E., Abrams J.M., et al. Genetic control of programmed cell death in Drosophila. Science 264 (1994) 677-683
-
(1994)
Science
, vol.264
, pp. 677-683
-
-
White, K.1
Grether, M.E.2
Abrams, J.M.3
-
123
-
-
0035049449
-
Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release
-
Whitfield J., Neame S.J., Paquet L., et al. Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release. Neuron 29 (2001) 629-643
-
(2001)
Neuron
, vol.29
, pp. 629-643
-
-
Whitfield, J.1
Neame, S.J.2
Paquet, L.3
-
124
-
-
0342331476
-
Cell death and apoptosis regulating proteins in Parkinson's disease-a cautionary note
-
Wullner U., Kornhuber J., Weller M., et al. Cell death and apoptosis regulating proteins in Parkinson's disease-a cautionary note. Acta Neuropathol (Berl) 97 (1999) 408-412
-
(1999)
Acta Neuropathol (Berl)
, vol.97
, pp. 408-412
-
-
Wullner, U.1
Kornhuber, J.2
Weller, M.3
-
125
-
-
0035964358
-
Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease
-
Xia X.G., Harding T., Weller M., et al. Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease. Proc Natl Acad Sci USA 98 (2001) 10433-10438
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10433-10438
-
-
Xia, X.G.1
Harding, T.2
Weller, M.3
-
126
-
-
0030780804
-
Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene
-
Yang D.D., Kuan C.Y., Whitmarsh A.J., et al. Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene. Nature 389 (1997) 865-870
-
(1997)
Nature
, vol.389
, pp. 865-870
-
-
Yang, D.D.1
Kuan, C.Y.2
Whitmarsh, A.J.3
-
127
-
-
0032531886
-
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2
-
Yang L., Matthews R.T., Schulz J.B., et al. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2. J Neurosci 18 (1998) 8145-8152
-
(1998)
J Neurosci
, vol.18
, pp. 8145-8152
-
-
Yang, L.1
Matthews, R.T.2
Schulz, J.B.3
-
128
-
-
0037067317
-
Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor
-
Yu S.W., Wang H., Poitras M.F., et al. Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science 297 (2002) 259-263
-
(2002)
Science
, vol.297
, pp. 259-263
-
-
Yu, S.W.1
Wang, H.2
Poitras, M.F.3
-
129
-
-
0027525104
-
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme
-
Yuan J., Shaham S., Ledoux S., et al. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme. Cell 75 (1993) 641-652
-
(1993)
Cell
, vol.75
, pp. 641-652
-
-
Yuan, J.1
Shaham, S.2
Ledoux, S.3
-
130
-
-
0032054744
-
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum
-
Zinszner H., Kuroda M., Wang X., et al. CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev 12 (1998) 982-995
-
(1998)
Genes Dev
, vol.12
, pp. 982-995
-
-
Zinszner, H.1
Kuroda, M.2
Wang, X.3
-
131
-
-
0034694199
-
Time course of degenerative alterations in nigral dopaminergic neurons following a 6-hydroxydopamine lesion
-
Zuch C.L., Nordstroem V.K., Briedrick L.A., et al. Time course of degenerative alterations in nigral dopaminergic neurons following a 6-hydroxydopamine lesion. J Comp Neurol 427 (2000) 440-454
-
(2000)
J Comp Neurol
, vol.427
, pp. 440-454
-
-
Zuch, C.L.1
Nordstroem, V.K.2
Briedrick, L.A.3
|