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Volumn 22, Issue 3, 2009, Pages 554-564

Delphinidin modulates the DNA-damaging properties of topoisomerase II poisons

Author keywords

[No Author keywords available]

Indexed keywords

DELPHINIDIN; DNA FORMAMIDOPYRIMIDINE GLYCOSYLASE; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE (ATP HYDROLYSING) ALPHA; DOXORUBICIN; ETOPOSIDE; UNCLASSIFIED DRUG;

EID: 65949104278     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx800293v     Document Type: Article
Times cited : (27)

References (79)
  • 1
    • 25444459913 scopus 로고    scopus 로고
    • Anthocyanidins modulate the activity of human DNA topoisomerases I and II and affect cellular DNA integrity
    • DOI 10.1021/tx050039n
    • Habermeyer, M., Fritz, J., Barthelmes, H. U., Christensen, M. O., Larsen, M. K., Boege, F., and Marko, D. (2005) Anthocyanidins modulate the activity of human DNA topoisomerases I and II and affect cellular DNA integrity. Chem. Res. Toxicol. 18, 1395-404. (Pubitemid 41361713)
    • (2005) Chemical Research in Toxicology , vol.18 , Issue.9 , pp. 1395-1404
    • Habermeyer, M.1    Fritz, J.2    Barthelmes, H.U.3    Christensen, M.O.4    Larsen, M.K.5    Boege, F.6    Marko, D.7
  • 4
    • 0043286281 scopus 로고    scopus 로고
    • Fruits and vegetables in the prevention of cellular oxidative damage
    • Prior, R. L. (2003) Fruits and vegetables in the prevention of cellular oxidative damage. Am. J. Clin. Nutr. 78, 570-578. (Pubitemid 40012551)
    • (2003) American Journal of Clinical Nutrition , vol.78 , Issue.SUPPL.
    • Prior, R.L.1
  • 5
    • 33646345590 scopus 로고    scopus 로고
    • Direct vasoactive and vasoprotective properties of anthocyanin-rich extracts
    • DOI 10.1152/japplphysiol.00626.2005
    • Bell, D. R., and Gochenaur, K. (2006) Direct vasoactive and vasoprotective properties of anthocyanin-rich extracts. J. Appl. Physiol. 100, 1164-70. (Pubitemid 43671473)
    • (2006) Journal of Applied Physiology , vol.100 , Issue.4 , pp. 1164-1170
    • Bell, D.R.1    Gochenaur, K.2
  • 6
    • 0032986801 scopus 로고    scopus 로고
    • Antioxidant and antiinflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherries
    • DOI 10.1021/np980501m
    • Wang, H., Nair, M. G., Strasburg, G. M., Chang, Y. C., Booren, A. M., Gray, J. I., and DeWitt, D. L. (1999) Antioxidant and antiinflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherries. J. Nat. Prod. 62, 802. (Pubitemid 29137910)
    • (1999) Journal of Natural Products , vol.62 , Issue.2 , pp. 294-296
    • Wang, H.1    Nair, M.G.2    Strasburg, G.M.3    Chang, Y.-C.4    Booren, A.M.5    Gray, J.I.6    DeWitt, D.L.7
  • 7
    • 0141513666 scopus 로고    scopus 로고
    • Inhibition of proliferation of human cancer cells and cyclooxygenase enzymes by anthocyanidins and catechins
    • Seeram, N. P., Zhang, Y., and Nair, M. G. (2003) Inhibition of proliferation of human cancer cells and cyclooxygenase enzymes by anthocyanidins and catechins. Nutr. Cancer 46, 101-106. (Pubitemid 37163297)
    • (2003) Nutrition and Cancer , vol.46 , Issue.1 , pp. 101-106
    • Seeram, N.P.1    Zhang, Y.2    Nair, M.G.3
  • 8
    • 15244353791 scopus 로고    scopus 로고
    • Molecular mechanisms behind the chemopreventive effects of anthocyanidins
    • PII S1110724304403040
    • Hou, D. X., Fujii, M., Terahara, N., and Yoshimoto, M. (2004) (2004) Molecular mechanisms behind the chemopreventive effects of anthocyanidins. J. Biomed. Biotechnol. 321-325. (Pubitemid 40389474)
    • (2004) Journal of Biomedicine and Biotechnology , vol.2004 , Issue.5 , pp. 321-325
    • Hou, D.-X.1    Fujii, M.2    Terahara, N.3    Yoshimoto, M.4
  • 9
    • 27644546239 scopus 로고    scopus 로고
    • Anthocyans from fruits and vegetables - Does bright colour signal cancer chemopreventive activity?
    • DOI 10.1016/j.ejca.2005.06.009
    • Cooke, D., Steward, W. P., Gescher, A. J., and Marczylo, T. H. (2005) Anthocyans from fruits and vegetablessdoes bright colour signal cancer chemopreventive activity? Eur. J. Cancer 41, 1931-40. (Pubitemid 41557679)
    • (2005) European Journal of Cancer , vol.41 , Issue.13 , pp. 1931-1940
    • Cooke, D.1    Steward, W.P.2    Gescher, A.J.3    Marczylo, T.4
  • 10
    • 0037592261 scopus 로고    scopus 로고
    • Dietary cyanidin 3-O-D-glucoside-rich purple corn color prevents obesity and ameliorates hyperglycemia in mice
    • Tsuda, T., Horio, F., Uchida, K., Aoki, H., and Osawa, T. (2003) Dietary cyanidin 3-O-beta-D-glucoside-rich purple corn color prevents obesity and ameliorates hyperglycemia in mice. J. Nutr. 133, 2125-30. (Pubitemid 36841527)
    • (2003) Journal of Nutrition , vol.133 , Issue.7 , pp. 2125-2130
    • Tsuda, T.1    Horio, F.2    Uchida, K.3    Aoki, H.4    Osawa, T.5
  • 12
    • 33748849064 scopus 로고    scopus 로고
    • Min mouse model of intestinal carcinogenesis - Relationship with tissue anthocyanin levels
    • DOI 10.1002/ijc.22090
    • Cooke, D., Schwarz, M., Boocock, D., Winterhalter, P., Steward, W. P., Gescher, A. J., and Marczylo, T. H. (2006) Effect of cyanidin-3-glucoside and an anthocyanin mixture from bilberry on adenoma development in the ApcMin mouse model of intestinal carcinogenesissrelationship with tissue anthocyanin levels. Int. J. Cancer 119, 2213-20. (Pubitemid 44423683)
    • (2006) International Journal of Cancer , vol.119 , Issue.9 , pp. 2213-2220
    • Cooke, D.1    Schwarz, M.2    Boocock, D.3    Winterhalter, P.4    Steward, W.P.5    Gescher, A.J.6    Marczylo, T.H.7
  • 13
    • 33846121301 scopus 로고    scopus 로고
    • Min mice fed suboptimal levels of sulindac
    • DOI 10.1021/jf0612169
    • Bobe, G., Wang, B., Seeram, N. P., Nair, M. G., and Bourquin, L. D. (2006) Dietary anthocyanin-rich tart cherry extract inhibits intestinal tumorigenesis in ApcMin mice fed suboptimal levels of sulindac. J. Agric. Food Chem. 54, 9322-8. (Pubitemid 46086088)
    • (2006) Journal of Agricultural and Food Chemistry , vol.54 , Issue.25 , pp. 9322-9328
    • Bobe, G.1    Wang, B.2    Seeram, N.P.3    Nair, M.G.4    Bourquin, L.D.5
  • 15
    • 21844468502 scopus 로고    scopus 로고
    • Effects of anthocyanidins on the inhibition of proliferation and induction of apoptosis in human gastric adenocarcinoma cells
    • Shih, P. H., Yeh, C. T., and Yen, G. C. (2005) Effects of anthocyanidins on the inhibition of proliferation and induction of apoptosis in human gastric adenocarcinoma cells. Food Chem. Toxicol. 43, 1557-66.
    • (2005) Food Chem. Toxicol. , vol.43 , pp. 1557-1566
    • Shih, P.H.1    Yeh, C.T.2    Yen, G.C.3
  • 16
    • 4744364585 scopus 로고    scopus 로고
    • Effects of commercial anthocyanin-rich extracts on colonic cancer and non tumorigenic colonic cell growth
    • Zhao, C., Giusti, M. M., Malik, M., Moyer, M. P., and Magnuson, B. A. (2004) Effects of commercial anthocyanin-rich extracts on colonic cancer and non tumorigenic colonic cell growth. J. Agric. Food Chem. 52, 6122-8.
    • (2004) J. Agric. Food Chem. , vol.52 , pp. 6122-8
    • Zhao, C.1    Giusti, M.M.2    Malik, M.3    Moyer, M.P.4    Magnuson, B.A.5
  • 17
    • 0242361615 scopus 로고    scopus 로고
    • Initial in vitro toxicity testing of functional foods rich in catechins and anthocyanins in human cells
    • DOI 10.1016/S0887-2333(03)00099-7
    • Glei, M., Matuschek, M., Steiner, C., Böhm, V., Persin, C., and Pool-Zobel, B. L. (2003) Initial in vitro toxicity testing of functional foods rich in catechins and anthocyanins in human cells. Toxicol. Vitro 17, 723-9. (Pubitemid 37352685)
    • (2003) Toxicology in Vitro , vol.17 , Issue.5-6 , pp. 723-729
    • Glei, M.1    Matuschek, M.2    Steiner, C.3    Bohm, V.4    Persin, C.5    Pool-Zobel, B.L.6
  • 18
    • 0035114407 scopus 로고    scopus 로고
    • The anthocyanidins cyanidin and delphinidin are potent inhibitors of the epidermal growth factor receptor
    • Meiers, S., Keme'ny, M., Weyand, U., Gastpar, R., von Angerer, E., and Marko, D. (2001) The anthocyanidins cyanidin and delphinidin are potent inhibitors of the epidermal growth factor receptor. J. Agric. Food Chem. 49, 958-962.
    • (2001) J. Agric. Food Chem. , vol.49 , pp. 958-962
    • Meiers, S.1    Keme'ny, M.2    Weyand, U.3    Gastpar, R.4    Von Angerer, E.5    Marko, D.6
  • 19
    • 9944249485 scopus 로고    scopus 로고
    • The substitution pattern of anthocyanidins affects different cellular signaling cascades regulating cell proliferation
    • DOI 10.1002/mnfr.200400034
    • Marko, D., Puppel, N., Tjaden, Z., Jakobs, S., and Pahlke, G. (2004) The substitution pattern of anthocyanidins affects different cellular signaling cascades regulating cell proliferation. Mol. Nutr. Food Res. 48, 318-325. (Pubitemid 39592264)
    • (2004) Molecular Nutrition and Food Research , vol.48 , Issue.4 , pp. 318-325
    • Marko, D.1    Puppel, N.2    Tjaden, Z.3    Jakobs, S.4    Pahlke, G.5
  • 20
    • 34250897841 scopus 로고    scopus 로고
    • The epidermal growth factor receptor and human topoisomerases represent potential cellular targets of oligomeric procyanidins
    • DOI 10.1002/mnfr.200600186
    • Fridrich, D., Kern, M., Fritz, J., Pahlke, G., Köhler, N., Winterhalter, P., and Marko, D. (2007) The epidermal growth factor receptor and human topoisomerases represent potential cellular targets of oligomeric procyanidins. Mol. Nutr. Food Res. 51, 192-200. (Pubitemid 47083250)
    • (2007) Molecular Nutrition and Food Research , vol.51 , Issue.2 , pp. 192-200
    • Fridrich, D.1    Kern, M.2    Fritz, J.3    Pahlke, G.4    Kohler, N.5    Winterhalter, P.6    Marko, D.7
  • 21
    • 0034923502 scopus 로고    scopus 로고
    • DNA topoisomerases: Structure, function, and mechanism
    • DOI 10.1146/annurev.biochem.70.1.369
    • Champoux, J. J. (2001) DNA topoisomerases: Structure, function, and mechanism. Annu. Rev. Biochem. 70, 369-413. (Pubitemid 32662215)
    • (2001) Annual Review of Biochemistry , vol.70 , pp. 369-413
    • Champoux, J.J.1
  • 23
    • 0026178922 scopus 로고
    • Catalytic function of DNA topoisomerase II
    • Osheroff, N., Zechiedrich, E. L., and Gale, K. C. (1991) Catalytic function of DNA topoisomerase II. Bioessays 13, 269-273. (Pubitemid 121000508)
    • (1991) BioEssays , vol.13 , Issue.6 , pp. 269-275
    • Osheroff, N.1    Lynn Zechiedrich, E.2    Gale, K.C.3
  • 24
    • 0035724690 scopus 로고    scopus 로고
    • DNA topoisomerases as targets for anticancer drugs
    • DOI 10.1046/j.1365-2710.2001.00368.x
    • Topcu, Z. (2001) DNA topoisomerases as targets for anticancer drugs. J. Clin. Pharm. Ther. 26, 405-16. (Pubitemid 34205966)
    • (2001) Journal of Clinical Pharmacy and Therapeutics , vol.26 , Issue.6 , pp. 405-416
    • Topcu, Z.1
  • 26
    • 4444358344 scopus 로고    scopus 로고
    • Camptothecins and topoisomerase I: A foot in the door. Targeting the genome beyond topoisomerase I with camptothecins and novel anticancer drugs: Importance of DNA replication, repair and cell cycle checkpoints
    • DOI 10.2174/1568011043352777
    • Pommier, Y. (2004) Camptothecins and topoisomerase I: A foot in the door. Targeting the genome beyond topoisomerase I with camptothecins and novel anticancer drugs: Importance of DNA replication, repair and cell cycle checkpoints. Curr. Med. Chem. Anticancer Agents 4, 429-34. (Pubitemid 39199346)
    • (2004) Current Medicinal Chemistry - Anti-Cancer Agents , vol.4 , Issue.5 , pp. 429-434
    • Pommier, Y.1
  • 27
    • 34447574853 scopus 로고    scopus 로고
    • Topoisomerase II-drug interaction domains: Identification of substituents on etoposide that interact with the enzyme
    • DOI 10.1021/bi700272u
    • Wilstermann, A. M., Bender, R. P., Godfre, M., Choi, S., Anklin, C., Berkowitz, D. B., Osheroff, N., and Graves, D. E. (2007) Topoisomerase II-drug interaction domains: Identification of substituents on etoposide that interact with the enzyme. Biochemistry 46, 8217-25. (Pubitemid 47075961)
    • (2007) Biochemistry , vol.46 , Issue.28 , pp. 8217-8225
    • Wilstermann, A.M.1    Bender, R.P.2    Godfrey, M.3    Choi, S.4    Anklin, C.5    Berkowitz, D.B.6    Osheroff, N.7    Graves, D.E.8
  • 28
    • 18244369481 scopus 로고    scopus 로고
    • The power and potential of doxorubicin-DNA adducts
    • DOI 10.1080/15216540500079093
    • Cutts, S. M., Nudelman, A., Rephaeli, A., and Phillips, D. R. (2005) The power and potential of doxorubicin-DNA adducts. IUBMB Life 57, 73-81. (Pubitemid 40632297)
    • (2005) IUBMB Life , vol.57 , Issue.2 , pp. 73-81
    • Cutts, S.M.1    Nudelman, A.2    Rephaeli, A.3    Phillips, D.R.4
  • 29
    • 0035914138 scopus 로고    scopus 로고
    • -epigallocatechin-3-gallate inhibits topoisomerase I activity in human colon carcinoma cells
    • Berger, S. J., Gupta, S., Belfi, C. A., Gosky, D. M., and Mukhtar, H. (2001) Green tea constituent (-)-epigallocatechin-3-gallate inhibits topoisomerase I activity in human colon carcinoma cells. Biochem. Biophys. Res. Commun. 288, 101-5.
    • (2001) Biochem. Biophys. Res. Commun. , vol.288 , pp. 101-105
    • Berger, S.J.1    Gupta, S.2    Belfi, C.A.3    Gosky, D.M.4    Mukhtar, H.5
  • 30
    • 33749622815 scopus 로고    scopus 로고
    • Topoisomerase II inhibition and high yield of endoreduplication induced by the flavonoids luteolin and quercetin
    • DOI 10.1093/mutage/gel033
    • Cantero, G., Campanella, C., Mateos, S., and Corte's, F. (2006) Topoisomerase II inhibition and high yield of endoreduplication induced by the flavonoids luteolin and quercetin. Mutagenesis 21, 321-5. (Pubitemid 44546415)
    • (2006) Mutagenesis , vol.21 , Issue.5 , pp. 321-325
    • Cantero, G.1    Campanella, C.2    Mateos, S.3    Cortes, F.4
  • 31
    • 0034493221 scopus 로고    scopus 로고
    • Distinct mechanisms of DNA damage in apoptosis induced by quercetin and luteolin
    • Yamashita, N., and Kawanishi, S. (2000) Distinct mechanisms of DNA damage in apoptosis induced by quercetin and luteolin. Free Radical Res. 33, 623-33. (Pubitemid 32103702)
    • (2000) Free Radical Research , vol.33 , Issue.5 , pp. 623-633
    • Yamashita, N.1    Kawanishi, S.2
  • 32
    • 0025189757 scopus 로고
    • Induction of mammalian topoisomerase II dependent DNA cleavage by nonintercalative flavonoids, genistein and orobol
    • DOI 10.1016/0006-2952(90)90153-C
    • Yamashita, Y., Kawada, S.-Z., and Nakano, H. (1990) Induction of mammalian topoisomerase II dependent DNA cleavage by nonitercalative flavonoids, genistein and orobol. Biochem. Pharmacol. 39, 737-744. (Pubitemid 20055769)
    • (1990) Biochemical Pharmacology , vol.39 , Issue.4 , pp. 737-744
    • Yamashita, Y.1    Kawada, S.-Z.2    Nakano, H.3
  • 34
    • 43149124005 scopus 로고    scopus 로고
    • -Epigallocatechin gallate, a major constituent of green tea, poisons human type II topoisomerases
    • Bandele, O. J., and Osheroff, N. (2008) (-)-Epigallocatechin gallate, a major constituent of green tea, poisons human type II topoisomerases. Chem. Res. Toxicol. 21, 936-43.
    • (2008) Chem. Res. Toxicol. , vol.21 , pp. 936-943
    • Bandele, O.J.1    Osheroff, N.2
  • 35
    • 47049094564 scopus 로고    scopus 로고
    • Dietary polyphenols as topoisomerase II poisons: B ring and C ring substituents determine the mechanism of enzyme-mediated DNA cleavage enhancement
    • Bandele, O. J., Clawson, S. J., and Osheroff, N. (2008) Dietary polyphenols as topoisomerase II poisons: B ring and C ring substituents determine the mechanism of enzyme-mediated DNA cleavage enhancement. Chem. Res. Toxicol. 21, 1253-60.
    • (2008) Chem. Res. Toxicol. , vol.21 , pp. 1253-1260
    • Bandele, O.J.1    Clawson, S.J.2    Osheroff, N.3
  • 36
    • 0035902490 scopus 로고    scopus 로고
    • DNA cleavage and religation by human topoisomerase II at high temperature
    • DOI 10.1021/bi010681q
    • Bromberg, K. D., and Osheroff, N. (2001) DNA cleavage and religation by human topoisomerase II alpha at high temperature. Biochemistry 40, 8410-08. (Pubitemid 32661901)
    • (2001) Biochemistry , vol.40 , Issue.28 , pp. 8410-8418
    • Bromberg, K.D.1    Osheroff, N.2
  • 37
    • 0033006172 scopus 로고    scopus 로고
    • A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin
    • DOI 10.1016/S0006-2952(98)00307-4, PII S0006295298003074
    • Gewirtz, D. A. (1999) A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. Biochem. Pharmacol. 57, 101-115. (Pubitemid 29094544)
    • (1999) Biochemical Pharmacology , vol.57 , Issue.7 , pp. 727-741
    • Gewirtz, D.A.1
  • 38
    • 0035219768 scopus 로고    scopus 로고
    • ICE bioassay. Isolating in vivo complexes of enzyme to DNA
    • Subramanian, D., Furbee, C. S., and Muller, M. T. (2001) ICE bioassay. Isolating in vivo complexes of enzyme to DNA. Methods Mol. Biol. 95, 137-47.
    • (2001) Methods Mol. Biol. , vol.95 , pp. 137-147
    • Subramanian, D.1    Furbee, C.S.2    Muller, M.T.3
  • 39
    • 12844275026 scopus 로고    scopus 로고
    • Mechanism of apoptosis induced by doxorubicin through the generation of hydrogen peroxide
    • DOI 10.1016/j.lfs.2004.05.040, PII S0024320504009877
    • Mizutani, H., Tada-Oikawa, S., Hiraku, Y., Kojima, M., and Kawanishi, S. (2005) Mechanism of apoptosis induced by doxorubicin through the generation of hydrogen peroxide. Life Sci. 76, 1439-53. (Pubitemid 40164773)
    • (2005) Life Sciences , vol.76 , Issue.13 , pp. 1439-1453
    • Mizutani, H.1    Tada-Oikawa, S.2    Hiraku, Y.3    Kojima, M.4    Kawanishi, S.5
  • 40
    • 0035797151 scopus 로고    scopus 로고
    • Mitochondria as subcellular targets for clinically useful anthracyclines
    • DOI 10.1016/S0169-409X(01)00128-4, PII S0169409X01001284
    • Jung, K., and Reszka, R. (2001) Mitochondria as subcellular targets for clinically useful anthracyclines. Adv. Drug Deliv. Rev. 49, 87-105. (Pubitemid 32493802)
    • (2001) Advanced Drug Delivery Reviews , vol.49 , Issue.1-2 , pp. 87-105
    • Jung, K.1    Reszka, R.2
  • 41
    • 0033006172 scopus 로고    scopus 로고
    • A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin
    • DOI 10.1016/S0006-2952(98)00307-4, PII S0006295298003074
    • Gewirtz, D. A. (1999) A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. Biochem. Pharmacol. 57, 727-41. (Pubitemid 29094544)
    • (1999) Biochemical Pharmacology , vol.57 , Issue.7 , pp. 727-741
    • Gewirtz, D.A.1
  • 42
    • 0026533905 scopus 로고
    • Excision of purine lesions in DNA produced by ionizing radiation or photosensitization
    • Substrate specificity of the Escherichia coli Fpg protein
    • Boiteux, S., Gajewski, E., Laval, J., and Dizdaroglu, M. (1992) Substrate specificity of the Escherichia coli Fpg protein (formamidopyrimidine-DNA glycosylase): Excision of purine lesions in DNA produced by ionizing radiation or photosensitization. Biochemistry 31, 106-10.
    • (1992) Biochemistry formamidopyrimidine-DNA glycosylase , vol.31 , pp. 106-110
    • Boiteux, S.1    Gajewski, E.2    Laval, J.3    Dizdaroglu, M.4
  • 43
    • 0032504157 scopus 로고    scopus 로고
    • Merbarone inhibits the catalytic activity of human topoisomerase II by blocking DNA cleavage
    • DOI 10.1074/jbc.273.28.17643
    • Fortune, J. M., and Osheroff, N. (1998) Merbarone inhibits the catalytic activity of human topoisomerase IIalpha by blocking DNA cleavage. J. Biol. Chem. 273, 643-50. (Pubitemid 28355102)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.28 , pp. 17643-17650
    • Fortune, J.M.1    Osheroff, N.2
  • 45
    • 34249317605 scopus 로고    scopus 로고
    • Bioflavonoids as poisons of human topoisomerase II and II
    • DOI 10.1021/bi7000664
    • Bandele, O. J., and Osheroff, N. (2007) Bioflavonoids as poisons of human topoisomerase II alpha and II beta. Biochemistry 46, 6097-108. (Pubitemid 46804906)
    • (2007) Biochemistry , vol.46 , Issue.20 , pp. 6097-6108
    • Bandele, O.J.1    Osheroff, N.2
  • 46
    • 10944248747 scopus 로고    scopus 로고
    • Comparative analysis of topoisomerase IB inhibition and DNA intercalation by flavonoids and similar compounds: Structural determinates of activity
    • DOI 10.1042/BJ20040474
    • Webb, M. R., and Ebeler, S. E. (2004) Comparative analysis of topoisomerase IB inhibition and DNA intercalation by flavonoids and similar compounds: Structural determinates of activity. Biochem. J. 384, 527-41. (Pubitemid 40018966)
    • (2004) Biochemical Journal , vol.384 , Issue.3 , pp. 527-541
    • Webb, M.R.1    Ebeler, S.E.2
  • 47
    • 16344367235 scopus 로고    scopus 로고
    • Effects of grape cell culture extracts on human topoisomerase II catalytic activity and characterization of active fractions
    • Jo, J. Y., Gonzalez de Mejia, E., and Lila, M. A. (2005) Effects of grape cell culture extracts on human topoisomerase II catalytic activity and characterization of active fractions. J. Agric. Food Chem. 53, 2489-98.
    • (2005) J. Agric. Food Chem. , vol.53 , pp. 2489-2498
    • Jo, J.Y.1    Gonzalez De Mejia, E.2    Lila, M.A.3
  • 48
    • 33645765580 scopus 로고    scopus 로고
    • Catalytic inhibition of human DNA topoisomerase II by interactions of grape cell culture polyphenols
    • Jo, J. Y., Gonzalez de Mejia, E., and Lila, M. A. (2006) Catalytic inhibition of human DNA topoisomerase II by interactions of grape cell culture polyphenols. J. Agric. Food Chem. 54, 2083-7.
    • (2006) J. Agric. Food Chem. , vol.54 , pp. 2083-7
    • Jo, J.Y.1    Gonzalez De Mejia, E.2    Lila, M.A.3
  • 49
    • 0036287867 scopus 로고    scopus 로고
    • DNA topoisomerase II as a target for cancer chemotherapy
    • DOI 10.1081/CNV-120002156
    • Walker, J. V., and Nitiss, J. L. (2002) DNA topoisomerase II as a target for cancer chemotherapy. Cancer Invest. 20, 570-89. (Pubitemid 34686351)
    • (2002) Cancer Investigation , vol.20 , Issue.4 , pp. 570-589
    • Walker, J.V.1    Nitiss, J.L.2
  • 50
    • 0035437139 scopus 로고    scopus 로고
    • Benzene metabolites antagonize etoposide-stabilized cleavable complexes of DNA topoisomerase IIalpha
    • Baker, R. K., Kurz, E. U., Pyatt, D. W., Irons, R. D., and Kroll, D. J. (2001) Benzene metabolites antagonize etoposide-stabilized cleavable complexes of DNA topoisomerase IIalpha. Blood 98, 830-3.
    • (2001) Blood , vol.98 , pp. 830-3
    • Baker, R.K.1    Kurz, E.U.2    Pyatt, D.W.3    Irons, R.D.4    Kroll, D.J.5
  • 51
    • 1642379266 scopus 로고    scopus 로고
    • N-Acetyl-p-benzoquinone Imine, the Toxic Metabolite of Acetaminophen, Is a Topoisomerase II Poison
    • DOI 10.1021/bi036107r
    • Bender, R. P., Jr., Burden, D. A., and Osheroff, N. (2004) N-Acetylp-benzoquinone imine, the toxic metabolite of acetaminophen, is a topoisomerase II poison. Biochemistry 43, 3731-9. (Pubitemid 38391728)
    • (2004) Biochemistry , vol.43 , Issue.12 , pp. 3731-3739
    • Bender, R.P.1    Lindsey, Jr.R.H.2    Burden, D.A.3    Osheroff, N.4
  • 52
    • 0026574138 scopus 로고
    • Site-specific DNA cleavage by mammalian DNA topoisomerase II induced by novel flavone and catechin derivatives
    • Austin, C. A., Patel, S., Ono, K., Nakane, H., and Fisher, L. M. (1992) Site-specific DNA cleavage by mammalian DNA topoisomerase II induced by novel flavone and catechin derivatives. Biochem. J. 282, 883-9.
    • (1992) Biochem. J. , vol.282 , pp. 883-9
    • Austin, C.A.1    Patel, S.2    Ono, K.3    Nakane, H.4    Fisher, L.M.5
  • 53
    • 2942527053 scopus 로고    scopus 로고
    • Interaction model for anthracycline activity against DNA topoisomerase II
    • DOI 10.1021/bi0361665
    • Moro, S., Beretta, G. L., Dal Ben, D., Nitiss, J., Palumbo, M., and Capranico, G. (2004) Interaction model for anthracycline activity against DNA topoisomerase II. Biochemistry 43, 7503-13. (Pubitemid 38745766)
    • (2004) Biochemistry , vol.43 , Issue.23 , pp. 7503-7513
    • Moro, S.1    Beretta, G.L.2    Dal Ben, D.3    Nitiss, J.4    Palumbo, M.5    Capranico, G.6
  • 54
    • 0029847080 scopus 로고    scopus 로고
    • Mechanisms of cell killing by drugs that trap covalent complexes between DNA topoisomerases and DNA
    • Nitiss, J. L., and Wang, J. C. (1996) Mechanisms of cell killing by drugs that trap covalent complexes between DNA topoisomerases and DNA. Mol. Pharmacol. 50, 1095-102. (Pubitemid 26384847)
    • (1996) Molecular Pharmacology , vol.50 , Issue.5 , pp. 1095-1102
    • Nitiss, J.L.1    Wang, J.C.2
  • 55
    • 0034678060 scopus 로고    scopus 로고
    • A mutation in yeast topoisomerase II that confers hypersensitivity to multiple classes of topoisomerase II poisons
    • DOI 10.1074/jbc.275.11.7980
    • Dong, J., Walker, J., and Nitiss, J. L. (2000) A mutation in yeast topoisomerase II that confers hypersensitivity to multiple classes of topoisomerase II poisons. J. Biol. Chem. 275, 7980-7. (Pubitemid 30159708)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.11 , pp. 7980-7987
    • Dong, J.1    Walker, J.2    Nitiss, J.L.3
  • 56
    • 0030007125 scopus 로고    scopus 로고
    • Mapping of DNA topoisomerase II poisons (etoposide, clerocidin) and catalytic inhibitors (aclarubicin, ICRF-187) to four distinct steps in the topoisomerase II catalytic cycle
    • Sehested, M., and Jensen, P. B. (1996) Mapping of DNA topoisomerase II poisons (etoposide, clerocidin) and catalytic inhibitors (aclarubicin, ICRF-187) to four distinct steps in the topoisomerase II catalytic cycle. Biochem. Pharmacol. 51, 879-86.
    • (1996) Biochem. Pharmacol , vol.51 , pp. 879-886
    • Sehested, M.1    Jensen, P.B.2
  • 60
    • 0034480302 scopus 로고    scopus 로고
    • Detection of DNA-strand breaks in cells treated with F 11782, a catalytic inhibitor of topoisomerases I and II
    • Barret, J. M., Montaudon, D., Etie'vant, C., Perrin, D., Kruczynski, A., Robert, J., and Hill, B. T. (2000) Detection of DNA-strand breaks in cells treated with F 11782, a catalytic inhibitor of topoisomerases I and II. Anticancer Res. 20, 4557-62. (Pubitemid 32141819)
    • (2000) Anticancer Research , vol.20 , Issue.B , pp. 4557-4562
    • Barret, J.-M.1    Montaudon, D.2    Etievant, C.3    Perrin, D.4    Kruczynski, A.5    Robert, J.6    Hill, B.T.7
  • 61
    • 33644754070 scopus 로고    scopus 로고
    • The effects of cranberry juice consumption on antioxidant status and biomarkers relating to heart disease and cancer in healthy human volunteers
    • DOI 10.1007/s00394-005-0572-9
    • Duthie, S. J., Jenkinson, A. M., Crozier, A., Mullen, W., Pirie, L., Kyle, J., Yap, L. S., Christen, P., and Duthie, G. G. (2006) The effects of cranberry juice consumption on antioxidant status and biomarkers relating to heart disease and cancer in healthy human volunteers. Eur. J. Nutr. 45, 113-22. (Pubitemid 43345204)
    • (2006) European Journal of Nutrition , vol.45 , Issue.2 , pp. 113-122
    • Duthie, S.J.1    Jenkinson, A.M.2    Crozier, A.3    Mullen, W.4    Pirie, L.5    Kyle, J.6    Yap, L.S.7    Christen, P.8    Duthie, G.G.9
  • 62
    • 0037471583 scopus 로고    scopus 로고
    • Antioxidant activity of anthocyanins and their aglycons
    • Kähkönen, M. P., and Heinonen, M. (2003) Antioxidant activity of anthocyanins and their aglycons. J. Agric. Food Chem. 51, 628-33.
    • (2003) J. Agric. Food Chem. , vol.51 , pp. 628-633
    • Kähkönen, M.P.1    Heinonen, M.2
  • 64
    • 0033214044 scopus 로고    scopus 로고
    • Molecular analysis of yeast and human type II topoisomerases: Enzyme-DNA and drug interactions
    • Strumberg, D., Nitiss, J. L., Dong, J., Kohn, K. W., and Pommier, Y. (1999) Molecular analysis of yeast and human type II topoisomerases. Enzyme-DNA and drug interactions. J. Biol. Chem. 274, 28246-55. (Pubitemid 129504688)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.40 , pp. 28246-28255
    • Strumberg, D.1    Nitiss, J.L.2    Dong, J.3    Kohn, K.W.4    Pommier, Y.5
  • 65
    • 33746060535 scopus 로고    scopus 로고
    • Roles of nonhomologous end-joining pathways in surviving topoisomerase II-mediated DNA damage
    • DOI 10.1158/1535-7163.MCT-05-0263
    • Malik, M., Nitiss, K. C., Enriquez-Rios, V., and Nitiss, J. L. (2006) Roles of nonhomologous end-joining pathways in surviving topoisomerase II-mediated DNA damage. Mol. Cancer Ther. 5, 1405-14. (Pubitemid 44070476)
    • (2006) Molecular Cancer Therapeutics , vol.5 , Issue.6 , pp. 1405-1414
    • Malik, M.1    Nitiss, K.C.2    Enriquez-Rios, V.3    Nitiss, J.L.4
  • 66
    • 50849141104 scopus 로고    scopus 로고
    • Early events in the mammalian response to DNA double-strand breaks
    • Riches, L. C., Lynch, A. M., and Gooderham, N. J. (2008) Early events in the mammalian response to DNA double-strand breaks. Mutagenesis 23, 331-9.
    • (2008) Mutagenesis , vol.23 , pp. 331-319
    • Riches, L.C.1    Lynch, A.M.2    Gooderham, N.J.3
  • 69
    • 0036223676 scopus 로고    scopus 로고
    • The poly(C)-binding proteins: A multiplicity of functions and a search for mechanisms
    • DOI 10.1017/S1355838202024627
    • Makeyev, A. V., and Liebhaber, S. A. (2002) The poly(C)-binding proteins: a multiplicity of functions and a search for mechanisms. RNA 8, 265-78. (Pubitemid 34311177)
    • (2002) RNA , vol.8 , Issue.3 , pp. 265-278
    • Makeyev, A.V.1    Liebhaber, S.A.2
  • 70
    • 33845572347 scopus 로고    scopus 로고
    • Glycoproteome profiling of transforming growth factor-beta (TGFbeta) signaling: Nonglycosylated cell deathinducing DFF-like effector A inhibits TGFbeta1-dependent apoptosis
    • Iwahana, H., Yakymovych, I., Dubrovska, A., Hellman, U., and Souchelnytskyi, S. (2006) Glycoproteome profiling of transforming growth factor-beta (TGFbeta) signaling: nonglycosylated cell deathinducing DFF-like effector A inhibits TGFbeta1-dependent apoptosis. Proteomics 6, 6168-80.
    • (2006) Proteomics , vol.6 , pp. 6168-6180
    • Iwahana, H.1    Yakymovych, I.2    Dubrovska, A.3    Hellman, U.4
  • 72
    • 65949092936 scopus 로고    scopus 로고
    • Delphinidin, an anthocyanidin in pigmented fruits and vegetables, induces apoptosis and cell cycle arrest in human colon cancer HCT116 cells.
    • [Online early access]
    • Yun, J. M., Afaq, F., Khan, N., and Mukhtar, H. (2008) Delphinidin, an anthocyanidin in pigmented fruits and vegetables, induces apoptosis and cell cycle arrest in human colon cancer HCT116 cells. Mol. Carcinog. [Online early access].
    • (2008) Mol. Carcinog.
    • Yun, J.M.1    Afaq, F.2    Khan, N.3    Mukhtar, H.4
  • 73
    • 0034033956 scopus 로고    scopus 로고
    • Genistein induces apoptosis and topoisomerase II-mediated DNA breakage in colon cancer cells
    • DOI 10.1016/S0959-8049(00)00017-4, PII S0959804900000174
    • Salti, G. I., Grewal, S., Mehta, R. R., Das, Gupta, T. K., Boddie, A. W., and Constantinou, A. I. (2000) Genistein induces apoptosis and topoisomerase II-mediated DNA breakage in colon cancer cells. Eur. J. Cancer 36, 796-802. (Pubitemid 30179753)
    • (2000) European Journal of Cancer , vol.36 , Issue.6 , pp. 796-802
    • Salti, G.I.1    Grewal, S.2    Mehta, R.R.3    Das Gupta, T.K.4    Boddie Jr., A.W.5    Constantinou, A.I.6
  • 74
    • 0037818408 scopus 로고    scopus 로고
    • Investigations into the concept of a threshold for topoisomerase inhibitor-induced clastogenicity
    • DOI 10.1093/mutage/geg003
    • Lynch, A., Harvey, J., Aylott, M., Nicholas, E., Burman, M., Siddiqui, A., Walker, S., and Rees, R. (2003) Investigations into the concept of a threshold for topoisomerase inhibitor-induced clastogenicity. Mutagenesis 18, 345-353. (Pubitemid 36850202)
    • (2003) Mutagenesis , vol.18 , Issue.4 , pp. 345-353
    • Lynch, A.1    Harvey, J.2    Aylott, M.3    Nicholas, E.4    Burman, M.5    Siddiqui, A.6    Walker, S.7    Rees, R.8
  • 75
    • 0032915558 scopus 로고    scopus 로고
    • Direct intestinal absorption of red fruit anthocyanins, cyanidin-3- glucoside and cyanidin-3, 5-diglucoside, into rats and humans
    • DOI 10.1021/jf9809582
    • Miyazawa, T., Nakagawa, K., Kudo, M., Muraishi, K., and Someya, K. (1999) Direct intestinal absorption of red fruit anthocyanins, cyanidin-3-glucoside and cyanidin-3, 5-diglucoside, into rats and humans. J. Agric. Food Chem. 47, 1083-1091. (Pubitemid 29182967)
    • (1999) Journal of Agricultural and Food Chemistry , vol.47 , Issue.3 , pp. 1083-1091
    • Miyazawa, T.1    Nakagawa, K.2    Kudo, M.3    Muraishi, K.4    Someya, K.5
  • 76
    • 0034833602 scopus 로고    scopus 로고
    • Orally administered delphinidin 3-rutinoside and cyanidin 3-rutinoside are directly absorbed in rats and humans and appear in the blood as the intact forms
    • Matsumoto, H., Inaba, H., Kishi, M., Tominaga, S., Hirayama, M., and Tsuda, T. (2001) Orally administered delphinidin 3-rutinoside and cyanidin 3-rutinoside are directly absorbed in rats and humans and appear in the blood as the intact forms. J. Agric. Food Chem. 49, 1546-1551.
    • (2001) J. Agric. Food Chem. , vol.49 , pp. 1546-1551
    • Matsumoto, H.1    Inaba, H.2    Kishi, M.3    Tominaga, S.4    Hirayama, M.5    Tsuda, T.6
  • 77
    • 34447540210 scopus 로고    scopus 로고
    • The bioavailability and absorption of anthocyanins: Towards a better understanding
    • DOI 10.1002/mnfr.200700092
    • McGhie, T. K., and Walton, M. C. (2007) The bioavailability and absorption of anthocyanins: towards a better understanding. Mol. Nutr. Food Res. 51, 702-13. (Pubitemid 47083681)
    • (2007) Molecular Nutrition and Food Research , vol.51 , Issue.6 , pp. 702-713
    • McGhie, T.K.1    Walton, M.C.2
  • 78
    • 34447636817 scopus 로고    scopus 로고
    • Availability of blueberry phenolics for microbial metabolism in the colon and the potential inflammatory implications
    • DOI 10.1002/mnfr.200700022
    • Russell, W. R., Labalt, A., Scobbie, L., and Duncan, S. H. (2007) Availability of blueberry phenolics for microbial metabolism in the colon and the potential inflammatory implications. Mol. Nutr. Food Res. 51, 726-731. (Pubitemid 47086264)
    • (2007) Molecular Nutrition and Food Research , vol.51 , Issue.6 , pp. 726-731
    • Russell, W.R.1    Labat, A.2    Scobbie, L.3    Duncan, S.H.4
  • 79
    • 33646240144 scopus 로고    scopus 로고
    • Studies on apple and blueberry fruit constituents: Do the polyphenols reach the colon after ingestion?
    • Kahle, K., Kraus, M., Scheppach, W., Ackermann, M., Ridder, F., and Richling, E. (2006) Studies on apple and blueberry fruit constituents: Do the polyphenols reach the colon after ingestion? Mol. Nutr. Food Res. 50, 418-23.
    • (2006) Mol. Nutr. Food Res. , vol.50 , pp. 418-423
    • Kahle, K.1    Kraus, M.2    Scheppach, W.3    Ackermann, M.4    Ridder, F.5    Richling, E.6


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