Tumor suppressor and oncogene actions of TGFBl occur early in skin carcinogenesis and are mediated by Smad3

Molecular Carcinogenesis

Volumn 48, Issue 5, 2009, Pages 441-453

  Bae, Dong Soon ^a   Blazanin, Nicholas ^b   Licata, Mathew ^b   Lee, Jessica ^a   Glick, Adam B ^b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Keratinocytes; Ras oncogene; Skin carcinogenesis; Smad3; TGFB1; Transcriptional profiling

Indexed keywords

CYTOKERATIN 8; PROTEINASE; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; BIOCHEMISTRY; CANCER GROWTH; CANCER INHIBITION; CELL ADHESION; CELL MIGRATION; CONTROLLED STUDY; ENZYME INDUCTION; EXTRACELLULAR MATRIX; GENE; GENE EXPRESSION; GENE MUTATION; GROWTH INHIBITION; KERATINOCYTE; MOUSE; NEWBORN; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SKIN CARCINOGENESIS; TUMOR GROWTH; TUMOR SUPPRESSOR GENE; V RAS GENE; ANIMAL; BAGG ALBINO MOUSE; CELL CULTURE; CULTURE MEDIUM; CYTOLOGY; DNA MICROARRAY; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; SKIN TUMOR;

ANIMALS; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; GENES, TUMOR SUPPRESSOR; KERATINOCYTES; MICE; MICE, INBRED BALB C; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ONCOGENES; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; SMAD3 PROTEIN; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA1;

EID: 65649153346     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20482     Document Type: Article

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