Evidence of a functional relationship between the nucleus accumbens shell and lateral hypothalamus subserving the control oil feeding behavior

Journal of Neuroscience

Volumn 19, Issue 24, 1999, Pages 11040-11048

  Stratford, Thomas R ^a,b   Kelley, An E ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b Neuropsychiatric Reserach Institure   (United States)

Author keywords

C fos; D( ) AP 5; Feeding behavior; GABA; Lateral hypothalamus; NMDA; Nucleus accumbens shell

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN C FOS;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CONTROLLED STUDY; FEEDING BEHAVIOR; GABAERGIC SYSTEM; LATERAL HYPOTHALAMUS; MALE; NERVE PROJECTION; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; SYNAPSE;

EID: 0033573532     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-24-11040.1999     Document Type: Article

References (30)

1. Bernardis LL, Bellinger LL (1996) The lateral hypothalamic area revisited: ingestive behavior. Neurosci Biohehav Rev 20:189-287.
2. Delgado J, Anand BK (1953) Increases in food intake induced by electrical stimulation of the lateral hypothalamus. Am J Physiol 172:162-168.
3. Heimer L, Zahm DS, Churchill L, Kalivas PW, Wohltmann C (1991) Specificity in the projection patterns of accumbal core and shell in the rat. Neuroscience 41:89-125.
4. Ikemoto S, Panksepp J (1996) Dissociations between appetitive and consummatory responses by pharmacological manipulations of reward-relevant brain regions. Behav Neurosci 110:331-345.
5. Kelly J, Alheid GF, Newberg A, Grossman SP (1977) GABA stimulation and blockade in the hypothalamus and midbrain: effects on feeding and locomotor activity. Pharmacol Biochem Behav 7:537-541.
6. King TR, Nance DM (1986) Neuroestrogenic control of feeding behavior and body weight in rats with kainic acid lesions of the lateral septal area. Physiol Behav 37:475-481.
7. Kirouac GJ, Ganguly PK (1995) Topographical organization in the nucleus accumbens of afferents from the basolateral amygdala and efferents to the lateral hypothalamus. Neuroscience 67:625-630.
8. Kotz CM, Billington CJ, Levine AS (1997) Opioids in the nucleus of the solitary tract are involved in feeding in the rat. Am J Physiol 272:R1028-R1032.
9. Maldonado-Irizarry CS, Swanson CJ, Kelley AE (1995) Glutamate receptors in the nucleus accumbens shell control feeding behavior via the lateral hypothalamus. J Neurosci 15:6779-6788.
10. Meredith GE, Wouterlood FG (1991) Synaptic organization of nucleus accumbens (ventral striatum). In: The basal ganglia III: advances in behavioral biology, Vol 39 (Carpenter MB, Di Chiara G, Morelli M, Stanzione P, eds), pp 167-176. New York: Plenum.
11. Meredith GE, Pennartz CM, Groenewegen HJ (1993) The cellular framework for chemical signalling in the nucleus accumbens. Prog Brain Res 99:3-24.
12. Miller NE (1960) Motivational effects of brain stimulation and drugs. Fed Proc 19:846-854.
13. Müller R, Bravo R, Burckhardt J, Curran T (1984) Induction of c-fos gene and protein by growth factors precedes activation of c-myc. Nature 312:716-720.
14. Paxinos G, Watson C (1997) The rat brain in stereotaxic coordinates. San Diego: Academic.
15. Pu S, Jain MR, Horvath TL, Diano S, Kalra PS, Kalra SP (1999) Interactions between neuropeptide Y and gamma-aminobutyric acid in stimulation of feeding: a morphological and pharmacological analysis. Endocrinology 140:933-940.
16. Salamone JD (1994) The involvement of nucleus accumbens dopamine in appetitive and aversive motivation. Behav Brain Res 61:117-133.
17. Sheng M, Greenberg ME (1990) The regulation and function of c-fos and other immediate early genes in the nervous system. Neuron 4:477-485.
18. Stanley BG, Leibowitz SF (1985) Neuropeptide Y injected in the paraventricular hypothalamus: a powerful stimulant of feeding behavior. Proc Natl Acad Sci USA 82:3940-3943.
19. Stanley BG, Lanthier D, Leibowitz SF (1988) Multiple brain sites sensitive to feeding stimulation by opioid agonists: a cannula-mapping study. Pharmacol Biochem Behav 31:825-832.
20. Stanley BG, Ha LH, Spears LC, Dee II MG, (1993a) Lateral hypothalamic injections of glutamate, kainic acid, D,L-α-amino3-hydroxy-5-methyl-isoxazole propionic acid or N-methyl-D-aspartic acid rapidly elicit intense transient eating in rats. Brain Res 613:88-95.
21. Stanley BG, Willett III VL, Donias HW, Ha LH, Spears LC (1993b) The lateral hypothalamus: a primary site mediating excitatory amino acid-elicited eating. Brain Res 630:41-49.
22. Stanley BG, Willett III VL, Donias HW, Dee II MG, Duva MA (1996) Lateral hypothalamic NMDA receptors and glutamate as physiological mediators of eating and weight control. Am J Physiol 270:R443-R449.
23. Stratford TR, Kelley AE (1997a) Feeding elicited by inhibition of neurons in the nucleus accumbens shell depends on activation of neurons in the lateral hypothalamus. Soc Neurosci Abstr 23:577.
24. Stratford TR, Kelley AE (1997b) GABA in the nucleus accumbens shell participates in the central regulation of feeding behavior. J Neurosci 17:4434-4440.
25. Stratford TR, Swanson CJ, Kelley AE (1998) Specific changes in food intake elicited by blockade or activation of glutamate receptors in the nucleus accumbens shell. Behav Brain Res 93:43-50.
26. A receptors in the medial ventral pallidum elicits feeding in satiated rats. Brain Res 825:199-203.
27. Tempel DL, Kim T, Leibowitz SF (1993) The paraventricular nucleus is uniquely responsive to the feeding stimulatory effects of steroid hormones. Brain Res 614:197-204.
28. Treece BR, Covasa M, Ritter RC, Burns GA (1998) Delay in meal termination follows blockade of N-methyl-D-aspartate receptors in the dorsal hindbrain. Brain Res 810:34-40.
29. Yoshida M, Yokoo H, Nakahara K, Tomita M, Hamada N, Ishikawa M, Hatakeyama J, Tanaka M, Nagatsu I (1997) Local muscimol disinhibits mesolimbic dopaminergic activity as examined by brain microdialysis and Fos immunohistochemistry. Brain Res 767:356-360.
30. Zahm DS, Brog JS (1992) On the significance of subterritories in the "accumbens" part of the rat ventral striatum. Neuroscience 50:751-767.