PTEN in neural precursor cells: Regulation of migration, apoptosis, and proliferation

Molecular and Cellular Neuroscience

Volumn 20, Issue 1, 2002, Pages 21-29

  Li, Li ^a   Liu, Fenghua ^a   Salmonsen, Rebecca A ^b   Turner, Tod K ^b   Litofsky, N Scott ^b   Di Cristofano, Antonio ^c   Pandolfi, Pier Paolo ^c   Jones, Stephen N ^b   Recht, Larry D ^b   Ross, Alonzo H ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL INVASION; CELL KINETICS; CELL MIGRATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GLIOMA; MACROCEPHALY; MENTAL DEFICIENCY; MOUSE; NONHUMAN; OLFACTORY BULB; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; STEM CELL; WESTERN BLOTTING;

ANIMALIA;

EID: 0036279763     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1006/mcne.2002.1115     Document Type: Article

References (51)

1. Estimation of nuclear populations from microtome sections
2. Autoradiographic and histological studies of postnatal neurogenesis. I. A longitudinal investigation of the kinetics, migration and transformation of cells incorporating tritiated thymidine in neonate rats, with special reference to postnatal neurogenesis in some brain regions
3. Adenoviral brain-derived neurotrophic factor induces both neostriatal and olfactory neuronal recruitment from endogenous progenitor cells in the adult forebrain
4. Tumor suppressors and oncogenes in cellular senescence
5. Disruption of Eph/ephrin signaling affects migration and proliferation in the adult subventricular zone
6. Migrational analysis of the constitutively proliferating subependyma population in adult mouse forebrain
7. In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain
8. Essential role of phosphoinositide metabolism in synaptic vesicle recycling
9. Cellular survival: A play in three Akts
10. +/- mice
11. Pten is essential for embryonic development and tumour suppression
12. Cowden syndrome and Lhermitte-Duclos disease in a family: A single genetic syndrome with pleiotropy?
13. 1 growth arrest in glioma cells
14. Importance of newly generated neurons in the adult olfactory bulb for odor discrimination
15. Bannayan-Riley-Ruvalcaba syndrome
16. Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo
17. Adult subventricular zone neuronal precursors continue to proliferate and migrate in the absence of the olfactory bulb
18. The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness
19. Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression
20. Pten regulates neuronal soma size: A mouse model of Lhermitte-Duclos disease
21. Regulation of PTEN expression in neuronal apoptosis
22. Embryonic precursor cells that express Trk receptors: Induction of different cell fates by NGF, BDNF, NT-3, and CNTF
23. A role for nuclear PTEN in neuronal differentiation
24. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
25. Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
26. Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases
27. Noggin antagonizes BMP signaling to create a niche for adult neurogenesis
28. Long-distance neuronal migration in the adult mammalian brain
29. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-triphosphate
30. PTEN and myotubularin: Novel phosphoinositide phosphatases
31. Malignant glioma: Genetics and biology of a grave matter
32. Neural stem cells in the adult mammalian forebrain: A relatively quiescent subpopulation of subependymal cells
33. Postmitotic death is the fate of constitutively proliferating cells in the subependymal layer of the adult mouse brain
34. A cell-survival factor (N-acetyl-L-cysteine) alters the in vivo fate of constitutively proliferating subependymal cells in the adult forebrain
35. The lipid phosphatase activity of PTEN is critical for its tumor suppressor function
36. Infusion of brain-derived neurotrophic factor into the lateral ventricle of the adult rat leads to new neurons in the parenchyma of the striatum, septum, thalamus, and hypothalamus
37. The subependymal layer in rodents: A site of structural plasticity and cell migration in the adult mammalian brain
38. A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes
39. Structure, function, and biology of SHIP proteins
40. PTEN: A newly identified regulator of neuronal differentiation
41. Differential expression of MMAC/PTEN in glioblastoma multiforme: Relationship to localization and prognosis
42. Erythropoietin regulates the in vitro and in vivo production of neuronal progenitors by mammalian forebrain neural stem cells
43. Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
44. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
45. PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway
46. High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice
47. T cell-specific loss of pten leads to defects in central and peripheral tolerance
48. Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
49. Transforming growth factor-α null and senescent mice show decreased neural progenitor cell proliferation in the forebrain subependyma
50. Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival
51. Adenovirus-mediated gene delvery into neuronal precursors of the adult mouse brain