Mapping the limits of substrate specificity of the adenylation domain of TycA

ChemBioChem

Volumn 10, Issue 4, 2009, Pages 671-682

  Villiers, Benoit R M ^a   Hollfelder, Florian ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Adenylation domain; Biosynthesis; Hydrophobic effect; Nonribosomal peptide synthesis; Substrate specificity

Indexed keywords

AMINO ACID; PHENYLALANINE TRANSFER RNA LIGASE; SYNTHETASE; TYROCIDINE; TYROCIDINE SYNTHETASE 1; UNCLASSIFIED DRUG;

ADENYLATION; AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; CHEMICAL REACTION; DRUG STRUCTURE; ENZYME SPECIFICITY; HYDROPHOBICITY; MICHAELIS MENTEN KINETICS; PRESSURE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN MODIFICATION;

ADENOSINE TRIPHOSPHATE; AMINO ACIDS; DIPHOSPHATES; KINETICS; MODELS, MOLECULAR; PEPTIDE SYNTHASES; PROTEIN STRUCTURE, TERTIARY; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

EID: 65549131891     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200800553     Document Type: Article

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