Decreasing the ring size of a cyclic nonribosomal peptide antibiotic by in-frame module deletion in the biosynthetic genes

Journal of the American Chemical Society

Volumn 124, Issue 37, 2002, Pages 10980-10981

  Mootz, Henning D ^a   Kessler, Nadine ^b   Linne, Uwe ^b   Eppelmann, Katrin ^b   Schwarzer, Dirk ^b   Marahiel, Mohamed A ^b  

^a ROCKEFELLER UNIVERSITY   (United States)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPEPTIDE; POLYPEPTIDE ANTIBIOTIC AGENT;

ARTICLE; CATALYSIS; DNA FLANKING REGION; GENE CASSETTE; GENE DELETION; GENE INSERTION; GENETIC RECOMBINATION; STEREOCHEMISTRY;

ANTI-BACTERIAL AGENTS; BACILLUS SUBTILIS; BACTERIAL PROTEINS; GENE DELETION; PEPTIDE SYNTHASES; PEPTIDES, CYCLIC; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY;

EID: 0037130634     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja027276m     Document Type: Article

References (20)