Mechanistic analysis of acyl transferase domain exchange in polyketide synthase modules

Journal of the American Chemical Society

Volumn 125, Issue 18, 2003, Pages 5366-5374

  Hans, Marcus ^b   Hornung, Andreas ^b   Dziarnowski, Agnieszka ^b   Cane, David E ^a   Khosla, Chaitan ^b  

^a Stanford University   (United States)

^b BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYST ACTIVITY; CONDENSATION; MOLECULAR STRUCTURE;

MECHANISTIC ANALYSIS;

ENZYME KINETICS;

3 OXOACYL ACYL CARRIER PROTEIN SYNTHASE; ACYLTRANSFERASE; POLYKETIDE SYNTHASE;

ANALYTIC METHOD; ARTICLE; CHEMICAL STRUCTURE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME DEGRADATION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SPECIFICITY; PROTEIN DOMAIN; SYNTHESIS;

ACYLTRANSFERASES; AMINO ACID SEQUENCE; BASE SEQUENCE; ESCHERICHIA COLI; KINETICS; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

EID: 0037617464     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja029539i     Document Type: Article

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