Utility of epimerization domains for the redesign of nonribosomal peptide synthetases

FEBS Journal

Volumn 272, Issue 17, 2005, Pages 4506-4520

  Stein, Daniel B ^a   Linne, Uwe ^a   Marahiel, Mohamed A ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Epimerization; Multienzyme; Nonribosomal peptide synthetase; Protein engineering

Indexed keywords

AMINO ACID; APOPROTEIN; CARRIER PROTEIN; COENZYME A; DEXTRO AMINO ACID; NONRIBOSOMAL PEPTIDE SYNTHETASE; PEPTIDYL CARRIER PROTEIN; PHOSPHOPANTETHEINYL TRANSFERASE SFP; SYNTHETASE; TRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; ENZYME MECHANISM; ENZYME MODIFICATION; ENZYME SPECIFICITY; EPIMERIZATION; EVALUATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METHYLATION; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; QUANTITATIVE ANALYSIS; STEREOCHEMISTRY;

AMINO ACID SEQUENCE; AMINO ACIDS; BACILLUS; BACTERIAL PROTEINS; BASE SEQUENCE; DNA, BACTERIAL; OLIGOPEPTIDES; PEPTIDE SYNTHASES; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

KOBUS;

EID: 24644474790     PISSN: 1742464X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2005.04871.x     Document Type: Article

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