Alveolar macrophage immaturity in infants and young children

European Respiratory Journal

Volumn 14, Issue 5, 1999, Pages 1198-1205

  Grigg, J ^b   Riedler, J ^c   Robertson, C F ^c   Boyle, W ^a   Uren, S ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

^c NONE

Author keywords

Alveolar macrophage; Bronchoalveolar lavage; Children; Immune receptor; T cells

Indexed keywords

ALBUMIN; CD14 ANTIGEN; CD68 ANTIGEN; CYTOKINE; ENDOTOXIN; HLA DR ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; INTERLEUKIN 6; NITROBLUE TETRAZOLIUM; TUMOR NECROSIS FACTOR; UREA;

ADOLESCENT; ARTICLE; CELL SIZE; CHILD; CONTROLLED STUDY; CYTOKINE RELEASE; HLA SYSTEM; HUMAN; HUMAN CELL; IMMATURITY; IMMUNE RESPONSE; INFANT; INFECTION SENSITIVITY; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE PROLIFERATION; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; T LYMPHOCYTE;

EID: 0032694891     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.99.14511989     Document Type: Article

References (33)

1. Holt PG. Postnatal maturation of immune competence during infancy and childhood. Pediatr Allergy Immunol 1995; 6: 59-70.
2. Holt PG. Immune tolerance and protection against allergic sensitization. Allergy 1995; 50: 34-36.
3. Anonymous. Bronchoalveolar lavage constituents in healthy individuals, idiopathic pulmonary fibrosis, and selected comparison groups. The BAL Cooperative Group Steering Committee. Am Rev Respir Dis 1990; 141: S169-S202.
4. Kurland G, Cheung AT, Miller ME, Ayin SA, Cho MM, Ford EW. The ontogeny of pulmonary defences: alveolar macrophage function in neonatal and juvenile rhesus monkeys. Pediatr Res 1988; 23: 293-297.
5. Spiteri MA, Poulter LW. Characterization of immune inducer and suppressor macrophages from the normal human lung. Clin Exp Immunol 1991; 83: 157-162.
6. Toews GB, Vial WC, Dunn MM, et al. The accessory cell function of human alveolar macrophages in specific T-cell proliferation. J Immunol 1984; 132: 181-186.
7. Grigg J, Kleinert S, Woods RL, et al. Alveolar epithelial lining fluid cellularity, protein and endothelin-1 in children with congenital heart disease. Eur Respir J 1996; 9: 1381-1388.
8. Rennard SI, Basset G, Lecossier D, et al. Estimation of volume of epithelial lining fluid recovered by lavage using urea as marker of dilution. J Appl Physiol 1986; 60: 532-538.
9. Uren S, Boyle W. Stimulation of allogeneic and autologous MLR by subpopulations of human monocytes. Transplant Proc 1989; 21: 208-210.
10. Hancock WW, Sayegh MH, Sablinski T, Kut JP, Kupiec-Weglinski JW, Milford EL. Blocking of mononuclear cell accumulation, cytokine production, and endothelial activation within rat cardiac allografts by CD4 monoclonal antibody therapy. Transplantation 1992; 53: 1276-1280.
11. Rook GA, Steele J, Umar S, Dockrell HM. A simple method for the solubilisation of reduced NBT, and its use as a colorimetric assay for activation of human macrophages by gamma-interferon. J Immunol Methods 1985; 82: 161-167.
12. Gearing AJ, Bird CR, Bristow A, Poole S, Thorpe R. A simple sensitive bioassay for interleukin-1 which is unresponsive to 10(3) U/ml of interleukin-2. J Immunol Methods 1987; 99: 7-11.
13. Van Snick J, Cayphas S, Vink A, et al. Purification and NH2-terminal aTnino acid sequence of a T-cell-derived lymphokine with growth factor activity for B-cell hybridomas. Proc Natl Acad Sci USA 1986; 83: 9679-9683.
14. Espevik T, Nissen-Meyer J. A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes. J Immunol Methods 1986; 95: 99-105.
15. Hansen MB, Nielsen SE, Berg K. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J Immunol Methods 1989; 119: 203-210.
16. O'Brien J, Knight S, Quick NA, Moore EH, Platt AS. A simple technique for harvesting lymphocytes cultured in Terasaki plates. J Immunol Methods 1979; 27: 219-223.
17. Betjes MG, Haks MC, Tuk CW, Beelen RH. Monoclonal antibody EBM1 1 (antiCD68) discriminates between dendritic cells and macrophages after short-term culture. Immunobiology 1991; 183: 79-87.
18. Marodi L, Kaposzta R, Campbell DE, Polin RA, Csongor J, Johnston RB Jr. Candidacidal mechanisms in the human neonate. Impaired IFN-gamma activation of macrophages in newborn infants. J Immunol 1994; 153: 5643-5649.
19. Lanzavecchia A. Mechanisms of antigen uptake for presentation. Curr Opin Immunol 1996; 8: 348-354.
20. Rozycki HJ. Elevated production of interleukin-1-beta from alveolar macrophages isolated from newborn rabbits. Biol Neonate 1994; 66: 93-99.
21. Bakker JM, Broug-Holub E, Kroes H, Rees EP, Kraal G, Iwaarden JF. Functional immaturity of rat alveolar macrophages during postnatal development. Immunology 1998; 94: 304-309.
22. Peters AM, Bertram P, Gahr M, Speer CP. Reduced secretion of interleukin-1 and tumor necrosis factor-alpha by neonatal monocytes. Biol Neonate 1993; 63: 157-162.
23. Pillay V, Savage N, Labum H. Circulating cytokine concentrations and cytokine production by monocytes from newborn babies and adults. Pflugers Arch 1994; 428: 197-201.
24. Dentener MA, Bazil V, von Asmuth EJ, Ceska M, Buurman WA. Involvement of CD 14 in lipopolysaccharide-induced tumor necrosis factor-alpha, IL-6 and IL-8 release by human monocytes and alveolar macrophages. J Immunol 1993; 150: 2885-2891.
25. Lynn WA, Liu Y, Golenbock DT. Neither CD14 nor serum is absolutely necessary for activation of mono-nuclear phagocytes by bacterial lipopolysaccharide. Infect Immun 1993; 61: 4452-4461.
26. Tang ML, Kemp AS, Thorburn J, Hill DJ. Reduced interferon-gamma secretion in neonates and subsequent atopy. Lancet 1994; 344: 983-985.
27. Hart PH, Bonder CS, Jones CA, Finlay-Jones JJ. Control of major histocompatibility complex class II expression on human monocytes by interleukin-4 regulatory effect of lipopolysaccharide. Immunology 1996; 89: 599-605.
28. Stiehm ER, Sztein MB, Steeg PS, et al. Deficient DR antigen expression on human cord blood monocytes: reversal with lymphokines. Clin Immunol Immunopathol 1984; 30: 430-436.
29. Ratjen F, Bredendiek M, Brendel M, Meltzer J, Costabel U. Differential cytology of bronchoalveolar lavage fluid in normal children. Eur Respir J 1994; 7: 1865-1870.
30. Riedler J, Grigg J, Stone C, Tauro G, Robertson CF. Bronchoalveolar lavage cellularity in healthy children. Am J Respir Crit Care Med 1995; 152: 163-168.
31. Weiss RA, Chanana AD, Joel DD. Postnatal maturation of pulmonary antimicrobial defense mechanisms in conventional and germ-free lambs. Pediatr Res 1986; 20: 496-504.
32. Zeligs BJ, Nerurkar LS, Bellanti JA, Zeligs JD. Maturation of the rabbit alveolar macrophage during animal development. I. Pennatal influx into alveoli and ultrastructural differentiation. Pediatr Res 1977; 11: 197-208.
33. Uren S, Boyle W. Isolation of a small monocyte subset with high accessory function: a dendritic cell precursor? Transplant Proc 1995; 27: 2172-2173.