Defining a link with asthma in mice congenitally deficient in eosinophils

Science

Volumn 305, Issue 5691, 2004, Pages 1773-1776

  Lee, James J ^a,b   Dimina, Dawn ^a,b   Macias, MiMi P ^a,b,e   Ochkur, Sergei I ^a,b   McGarry, Michael P ^a,b   O'Neill, Katie R ^a,b   Protheroe, Cheryl ^a,b   Pero, Ralph ^a,b   Nguyen, Thanh ^a,b   Cormier, Stephania A ^a,b,f   Lenkiewicz, Elizabeth ^a,b   Colbert, Dana ^a,b   Rinaldi, Lisa ^c   Ackerman, Steven J ^d   Irvin, Charles G ^c   Lee, Nancy A ^a,b  

^a MAYO CLINIC   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

^c UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF ILLINOIS   (United States)

^e Ear Foundation of Arizona   (United States)

^f LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; HEALTH CARE; PATIENT TREATMENT; SOCIAL SCIENCES;

ALLERGIC DISEASES; EOSINOPHILS; INFLAMMATORY CELLS; TRANSGENIC LINES;

CELLS;

ALLERGEN; DIPHTHERIA TOXIN; DIPHTHERIA TOXIN FRAGMENT A; EOSINOPHIL PEROXIDASE; OVALBUMIN; PEPTIDE FRAGMENT; PEROXIDASE;

MEDICINE;

ALLERGIC DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTHMA; CARCINOGENESIS; CONTROLLED STUDY; EOSINOPHIL; GRANULOCYTE; HEMATOPOIETIC CELL; INFLAMMATORY CELL; LUNG; MOUSE; NONHUMAN; PARASITOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY TRACT MUCOSA; TRANSGENIC MOUSE; WILD TYPE; ANIMAL; GENE TARGETING; GENETICS; IMMUNOLOGY; LEUKOCYTE COUNT; MUCUS; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RESPIRATORY TRACT ALLERGY; SECRETION;

ANIMALIA; MUS MUSCULUS;

ALLERGENS; ANIMALS; ASTHMA; DIPHTHERIA TOXIN; EOSINOPHIL PEROXIDASE; EOSINOPHILS; GENE TARGETING; LEUKOCYTE COUNT; LUNG; MICE; MICE, TRANSGENIC; MODELS, ANIMAL; MUCUS; OVALBUMIN; PEPTIDE FRAGMENTS; PEROXIDASES; RESPIRATORY HYPERSENSITIVITY;

EID: 4544304222     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1099472     Document Type: Article

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30. We wish to acknowledge the kind gift of the gene encoding DTA by I. Maxwell. We also thank the Mayo Clinic Arizona Core Facilities (L. Barbarisi, T. Brehm-Gibson, S. Savarirayan, M. Ruona, B. Schimeck, J. Caplette, and J. Protheroe) and our administrative staff (L. Mardel, J. Ford, and P. McGarry). Supported by the Mayo Foundation; an American Heart Association grant to J.J.L. (no. 045580Z); grants from NIH to J.J.L. (no. HL065228), N.A.L. (no. HL058723), S.J.A. (nos. AI033043 and AI025230), and C.G.I. (nos. NCRR-COBRE P20RR15557, P01-HL67004, and HL-EB67273); and by NIH postdoctoral fellowships to MM.P.M. (no. HL10105) and S.A.C. (no. AR08545).