Signal peptide peptidases: A family of intramembrane-cleaving proteases that cleave type 2 transmembrane proteins

Seminars in Cell and Developmental Biology

Volumn 20, Issue 2, 2009, Pages 225-230

  Golde, Todd E ^a   Wolfe, Michael S ^b   Greenbaum, Doron C ^c  

^a MAYO CLINIC   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Gamma secretase; Intramembrane cleaving proteases (I CLiPs); Presenilin; Signal peptide peptidase (SPP); Signal peptide peptidase like (SPPL)

Indexed keywords

ANTERIOR PHARYNX DEFECTIVE 1 PROTEIN; GAMMA SECRETASE; INTRAMEMBRANE CLEAVING ASPARTYL PROTEASE; INTRAMEMBRANE CLEAVING PROTEASE; MEMBRANE PROTEIN; NICASTRIN; PEPTIDASE; PRESENILIN; PROTEIN PEN 2; PROTEIN SPPL2A; PROTEIN SPPL3; SIGNAL PEPTIDE; SIGNAL PEPTIDE PEPTIDASE; UNCLASSIFIED DRUG;

CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; REVIEW;

EUKARYOTA; FUNGI; PROTOZOA;

EID: 63949088399     PISSN: 10849521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semcdb.2009.02.003     Document Type: Review

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