-
1
-
-
2942557122
-
Gamma-secretase: proteasome of the membrane?
-
Kopan R., and Ilagan M.X. Gamma-secretase: proteasome of the membrane?. Nat. Rev. Mol. Cell. Biol. 5 (2004) 499-504
-
(2004)
Nat. Rev. Mol. Cell. Biol.
, vol.5
, pp. 499-504
-
-
Kopan, R.1
Ilagan, M.X.2
-
2
-
-
0037304947
-
Intramembrane-cleaving proteases: controlled liberation of proteins and bioactive peptides
-
Weihofen A., and Martoglio B. Intramembrane-cleaving proteases: controlled liberation of proteins and bioactive peptides. Trends Cell Biol. 13 2 (2003) 71-78
-
(2003)
Trends Cell Biol.
, vol.13
, Issue.2
, pp. 71-78
-
-
Weihofen, A.1
Martoglio, B.2
-
3
-
-
20444429794
-
Drosophila signal peptide peptidase is an essential protease for larval development
-
Casso D.J., Tanda S., Biehs B., Martoglio B., and Kornberg T.B. Drosophila signal peptide peptidase is an essential protease for larval development. Genetics 170 (2005) 139-148
-
(2005)
Genetics
, vol.170
, pp. 139-148
-
-
Casso, D.J.1
Tanda, S.2
Biehs, B.3
Martoglio, B.4
Kornberg, T.B.5
-
4
-
-
14244268498
-
Gamma-secretase exists on the plasma membrane as an intact complex that accepts substrates and effects intramembrane cleavage
-
Chyung J.H., Raper D.M., and Selkoe D.J. Gamma-secretase exists on the plasma membrane as an intact complex that accepts substrates and effects intramembrane cleavage. J. Biol. Chem. 280 (2005) 4383-4392
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 4383-4392
-
-
Chyung, J.H.1
Raper, D.M.2
Selkoe, D.J.3
-
5
-
-
0037150672
-
Identification of signal peptide peptidase, a presenilin-type aspartic protease
-
Weihofen A., Binns K., Lemberg M.K., Ashman K., and Martoglio B. Identification of signal peptide peptidase, a presenilin-type aspartic protease. Science 296 (2002) 2215-2218
-
(2002)
Science
, vol.296
, pp. 2215-2218
-
-
Weihofen, A.1
Binns, K.2
Lemberg, M.K.3
Ashman, K.4
Martoglio, B.5
-
6
-
-
9444239782
-
A misassembled transmembrane domain of a polytopic protein associates with signal peptide peptidase
-
Crawshaw S.G., Martoglio B., Meacock S.L., and High S. A misassembled transmembrane domain of a polytopic protein associates with signal peptide peptidase. Biochem. J. 384 (2004) 9-17
-
(2004)
Biochem. J.
, vol.384
, pp. 9-17
-
-
Crawshaw, S.G.1
Martoglio, B.2
Meacock, S.L.3
High, S.4
-
7
-
-
20444481683
-
A novel transmembrane topology of presenilin based on reconciling experimental and computational evidence
-
Henricson A., Kall L., and Sonnhammer E.L. A novel transmembrane topology of presenilin based on reconciling experimental and computational evidence. FEBS J. 272 (2005) 2727-2733
-
(2005)
FEBS J.
, vol.272
, pp. 2727-2733
-
-
Henricson, A.1
Kall, L.2
Sonnhammer, E.L.3
-
8
-
-
10944270703
-
Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins
-
Friedmann E., Lemberg M.K., Weihofen A., Dev K.K., Dengler U., Rovelli G., and Martoglio B. Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins. J. Biol. Chem. 279 (2004) 50790-50798
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 50790-50798
-
-
Friedmann, E.1
Lemberg, M.K.2
Weihofen, A.3
Dev, K.K.4
Dengler, U.5
Rovelli, G.6
Martoglio, B.7
-
9
-
-
5644240819
-
A signal peptide peptidase (SPP) reporter activity assay based on the cleavage of type II membrane protein substrates provides further evidence for an inverted orientation of the SPP active site relative to presenilin
-
Nyborg A.C., Jansen K., Ladd T.B., Fauq A., and Golde T.E. A signal peptide peptidase (SPP) reporter activity assay based on the cleavage of type II membrane protein substrates provides further evidence for an inverted orientation of the SPP active site relative to presenilin. J. Biol. Chem. 279 (2004) 43148-43156
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 43148-43156
-
-
Nyborg, A.C.1
Jansen, K.2
Ladd, T.B.3
Fauq, A.4
Golde, T.E.5
-
10
-
-
2442446430
-
Signal peptide peptidase forms a homodimer that is labeled by an active site-directed gamma-secretase inhibitor
-
Nyborg A.C., Kornilova A.Y., Jansen K., Ladd T.B., Wolfe M.S., and Golde T.E. Signal peptide peptidase forms a homodimer that is labeled by an active site-directed gamma-secretase inhibitor. J. Biol. Chem. 279 (2004) 15153-15160
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 15153-15160
-
-
Nyborg, A.C.1
Kornilova, A.Y.2
Jansen, K.3
Ladd, T.B.4
Wolfe, M.S.5
Golde, T.E.6
-
11
-
-
28244456207
-
Differential localization and identification of a critical aspartate suggest non-redundant proteolytic functions of the presenilin in homologues SPPL2b and SPPL3
-
Krawitz P., Haffner C., Fluhrer R., Steiner H., Schmid B., and Haass C. Differential localization and identification of a critical aspartate suggest non-redundant proteolytic functions of the presenilin in homologues SPPL2b and SPPL3. J. Biol. Chem. 280 (2005) 39515-39523
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 39515-39523
-
-
Krawitz, P.1
Haffner, C.2
Fluhrer, R.3
Steiner, H.4
Schmid, B.5
Haass, C.6
-
12
-
-
0037930851
-
Targeting presenilin-type aspartic protease signal peptide peptidase with gamma-secretase inhibitors
-
Weihofen A., Lemberg M.K., Friedmann E., Rueeger H., Schmitz A., Paganetti P., Rovelli G., and Martoglio B. Targeting presenilin-type aspartic protease signal peptide peptidase with gamma-secretase inhibitors. J. Biol. Chem. 278 (2003) 16528-16533
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 16528-16533
-
-
Weihofen, A.1
Lemberg, M.K.2
Friedmann, E.3
Rueeger, H.4
Schmitz, A.5
Paganetti, P.6
Rovelli, G.7
Martoglio, B.8
-
13
-
-
0042786828
-
Expression of the presenilin-like signal peptide peptidase (SPP) in mouse adult brain and during development
-
Urny J., Hermans-Borgmeyer I., Gercken G., and Schaller H.C. Expression of the presenilin-like signal peptide peptidase (SPP) in mouse adult brain and during development. Gene Expr. Patterns 3 (2003) 685-691
-
(2003)
Gene Expr. Patterns
, vol.3
, pp. 685-691
-
-
Urny, J.1
Hermans-Borgmeyer, I.2
Gercken, G.3
Schaller, H.C.4
-
14
-
-
0035956996
-
Analysis of endoplasmic reticulum trafficking signals by combinatorial screening in mammalian cells
-
Zerangue N., Malan M.J., Fried S.R., Dazin P.F., Jan Y.N., Jan L.Y., and Schwappach B. Analysis of endoplasmic reticulum trafficking signals by combinatorial screening in mammalian cells. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 2431-2436
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 2431-2436
-
-
Zerangue, N.1
Malan, M.J.2
Fried, S.R.3
Dazin, P.F.4
Jan, Y.N.5
Jan, L.Y.6
Schwappach, B.7
-
15
-
-
0026731788
-
Protein disulfide isomerase. A multifunctional protein resident in the lumen of the endoplasmic reticulum
-
Noiva R., and Lennarz W.J. Protein disulfide isomerase. A multifunctional protein resident in the lumen of the endoplasmic reticulum. J. Biol. Chem. 267 (1992) 3553-3556
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 3553-3556
-
-
Noiva, R.1
Lennarz, W.J.2
-
16
-
-
6944250394
-
The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins
-
Grigorenko A.P., Moliaka Y.K., Soto M.C., Mello C.C., and Rogaev E.I. The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 14955-14960
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 14955-14960
-
-
Grigorenko, A.P.1
Moliaka, Y.K.2
Soto, M.C.3
Mello, C.C.4
Rogaev, E.I.5
|