SCOPUS 정보 검색 플랫폼

Volumn 9, Issue 11, 2001, Pages 3065-3075

Design, synthesis and pharmacological evaluation of 3-benzylazetidine-2-one-based human chymase inhibitors

(8) Aoyama, Yasunori a Uenaka, Masaaki a Kii, Makoto a Tanaka, Mamoru a Konoike, Toshiro a Hayasaki Kajiwara, Yoko a Naya, Noriyuki a Nakajima, Masatoshi a

a SHIONOGI AND CO LTD (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3 BENZYL 4 (4 METHYLPIPERAZINYLCARBONYL)PHENOXY 1 [1 (PHENYLETHYL)AMINOCARBONYL]AZETIDIN 2 ONE; 3 BENZYLAZETIDIN 2 ONE DERIVATIVE; 4 (4 CARBOXYPHENOXY) 1 [(DIPHENYLMETHYL)AMINOCARBONYL] 3 (2 ETHOXYBENZYL)AZETIDIN 2 ONE; AZETIDINONE DERIVATIVE; CATHEPSIN G; CHYMASE; CHYMOTRYPSIN A; ENZYME INHIBITOR; TRYPSIN; UNCLASSIFIED DRUG; AZETIDINE DERIVATIVE; FUNCTIONAL GROUP; N [1 (1,3 BENZODIOXOL 5 YL)BUTYL] 3,3 DIETHYL 2 [4 [(4 METHYL 1 PIPERAZINYL)CARBONYL]PHENOXY] 4 OXO 1 AZETIDINECARBOXAMIDE;

ARTICLE; DRUG DESIGN; DRUG SPECIFICITY; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME STABILITY; HUMAN; IN VITRO STUDY; NUCLEAR MAGNETIC RESONANCE; PLASMA; STRUCTURE ACTIVITY RELATION; CHEMICAL REACTION; DRUG STRUCTURE; REACTION ANALYSIS;

AZETIDINES; BLOOD; CHYMASES; DRUG DESIGN; HUMANS; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034801226 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/S0968-0896(01)00209-7 Document Type: Article

Times cited : (62)

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