Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: Should we keep our HATs on?

Arthritis Research and Therapy

Volumn 10, Issue 5, 2008, Pages

  Grabiec, Aleksander M ^a   Tak, Paul P ^a   Reedquist, Kris A ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ARYLBUTYRIC ACID DERIVATIVE; DOXORUBICIN; GLUCOCORTICOID; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE; N (2 AMINOPHENYL) 4 (3 PYRIDINYLMETHOXYCARBONYLAMINOMETHYL)BENZAMIDE; PROTEIN P53; ROMIDEPSIN; SIRTUIN 1; STAT PROTEIN; TRANSCRIPTION FACTOR FOXO; TRICHOSTATIN A; VORINOSTAT;

ACETYLATION; ANGIOGENESIS; APOPTOSIS; ARTHRITIS; ASTHMA; BONE EROSION; CARTILAGE CELL; CATABOLISM; CELL ACTIVATION; CELL CYCLE ARREST; CELL PROLIFERATION; CELL SURVIVAL; CHRONIC INFLAMMATION; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVITY; EPIGENETICS; FIBROBLAST; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION; HUMAN; MACROPHAGE ACTIVATION; MONOCYTE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; SYNOVIOCYTE; T LYMPHOCYTE ACTIVATION; TRANSCRIPTION REGULATION; ANIMAL; ENZYMOLOGY; GENETICS; INFLAMMATION; METABOLISM;

ANIMALS; ARTHRITIS, RHEUMATOID; ASTHMA; GENE EXPRESSION REGULATION; HISTONE DEACETYLASES; HUMANS; INFLAMMATION;

EID: 60549085246     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar2489     Document Type: Review

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