Benzodiazepine ligands can act as allosteric modulators of the Type 1 cholecystokinin receptor

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 15, 2008, Pages 4401-4404

  Gao, Fan ^a   Sexton, Patrick M ^b   Christopoulos, Arthur ^b   Miller, Laurence J ^a  

^a MAYO GRADUATE SCHOOL   (United States)

^b MONASH UNIVERSITY   (Australia)

Author keywords

Allosteric modulators; Cholecystokinin receptor; Cooperativity; G protein coupled receptors

Indexed keywords

BENZODIAZEPINE DERIVATIVE; CHOLECYSTOKININ; CHOLECYSTOKININ A RECEPTOR; DEVAZEPIDE;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DISSOCIATION; LIGAND BINDING; NONHUMAN;

ALLOSTERIC REGULATION; BENZODIAZEPINES; DEVAZEPIDE; LIGANDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; RECEPTORS, CHOLECYSTOKININ; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 47749152194     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.06.053     Document Type: Article

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