-
1
-
-
33645104470
-
SUSPECTS: enabling fast and effective prioritization of positional candidates
-
Adie, E.A. et al. (2006) SUSPECTS: enabling fast and effective prioritization of positional candidates, Bioinformatics 22: 773–774.
-
(2006)
Bioinformatics
, vol.22
, pp. 773-774
-
-
Adie, E.A.1
-
2
-
-
33646568805
-
Gene prioritization through genomic data fusion
-
Aerts, S. et al. (2006) Gene prioritization through genomic data fusion, Nat Biotechnol 24: 537–544.
-
(2006)
Nat Biotechnol
, vol.24
, pp. 537-544
-
-
Aerts, S.1
-
3
-
-
25144459980
-
The metabolic syndrome – a new worldwide definition
-
Alberti, K.G. et al. (2005) The metabolic syndrome – a new worldwide definition, Lancet 366: 1059–1062.
-
(2005)
Lancet
, vol.366
, pp. 1059-1062
-
-
Alberti, K.G.1
-
4
-
-
0031851293
-
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
-
Alberti, K.G., Zimmet, P.Z. (1998) Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation, Diabet Med 15: 539–553.
-
(1998)
Diabet Med
, vol.15
, pp. 539-553
-
-
Alberti, K.G.1
Zimmet, P.Z.2
-
5
-
-
0033624575
-
The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
-
Altshuler, D. et al. (2000) The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes, Nat Genet 26: 76–80.
-
(2000)
Nat Genet
, vol.26
, pp. 76-80
-
-
Altshuler, D.1
-
6
-
-
31444432748
-
T polymorphism with components of the metabolic syndrome in white Danes
-
Studies of the association of the GNB 3 825C
-
Andersen, G. et al. (2006) Studies of the association of the GNB 3 825C> T polymorphism with components of the metabolic syndrome in white Danes, Diabetologia 49: 75–82.
-
(2006)
Diabetologia
, vol.49
, pp. 75-82
-
-
Andersen, G.1
-
7
-
-
0036309976
-
Factors of insulin resistance syndrome – related phenotypes are linked to genetic locations on chromosomes 6 and 7 in nondiabetic mexican–americans
-
Arya, R. et al. (2002) Factors of insulin resistance syndrome – related phenotypes are linked to genetic locations on chromosomes 6 and 7 in nondiabetic mexican–americans, Diabetes 51: 841–847.
-
(2002)
Diabetes
, vol.51
, pp. 841-847
-
-
Arya, R.1
-
8
-
-
0025297450
-
Fetal and placental size and risk of hypertension in adult life
-
Barker, D.J. et al. (1990) Fetal and placental size and risk of hypertension in adult life, Br Med J 301: 259–262.
-
(1990)
Br Med J
, vol.301
, pp. 259-262
-
-
Barker, D.J.1
-
9
-
-
34147216956
-
A review of the genetics of essential hypertension
-
Binder, A. (2007) A review of the genetics of essential hypertension, Curr Opin Cardiol 22: 176–184.
-
(2007)
Curr Opin Cardiol
, vol.22
, pp. 176-184
-
-
Binder, A.1
-
10
-
-
34249997024
-
Replicating genotype– phenotype associations
-
Chanock, S.J. et al. (2007) Replicating genotype– phenotype associations, Nature 447: 655–660.
-
(2007)
Nature
, vol.447
, pp. 655-660
-
-
Chanock, S.J.1
-
11
-
-
15044339157
-
Role of the PPAR family of nuclear receptors in the regulation of metabolic and cardiovascular homeostasis: new approaches to therapy
-
Chinetti-Gbaguidi, G. et al. (2005) Role of the PPAR family of nuclear receptors in the regulation of metabolic and cardiovascular homeostasis: new approaches to therapy, Curr Opin Pharmacol 5: 177–183.
-
(2005)
Curr Opin Pharmacol
, vol.5
, pp. 177-183
-
-
Chinetti-Gbaguidi, G.1
-
12
-
-
0030876952
-
Valvular heart disease associated with fenfluramine–phentermine
-
Connolly, H.M. et al. (1997) Valvular heart disease associated with fenfluramine–phentermine, N Engl J Med 337: 581–588.
-
(1997)
N Engl J Med
, vol.337
, pp. 581-588
-
-
Connolly, H.M.1
-
13
-
-
1842830623
-
The ACE insertion / deletion polymorphism is not associated with the metabolic syndrome (WHO Definition) in Brazilian type 2 diabetic patients
-
Costa, L.A. et al. (2002) The ACE insertion / deletion polymorphism is not associated with the metabolic syndrome (WHO Definition) in Brazilian type 2 diabetic patients, Diabetes Care 25: 2365–2366.
-
(2002)
Diabetes Care
, vol.25
, pp. 2365-2366
-
-
Costa, L.A.1
-
14
-
-
33750202275
-
The genetic dissection of essential hypertension
-
Cowley, A.W. (2006) The genetic dissection of essential hypertension, Nat Rev Genet 7: 829–840.
-
(2006)
Nat Rev Genet
, vol.7
, pp. 829-840
-
-
Cowley, A.W.1
-
15
-
-
33845886915
-
Abdominal obesity and metabolic syndrome
-
Despres, J.P. and Lemieux, I. (2006) Abdominal obesity and metabolic syndrome, Nature 444: 881–887.
-
(2006)
Nature
, vol.444
, pp. 881-887
-
-
Despres, J.P.1
Lemieux, I.2
-
16
-
-
0033305213
-
Peroxisome proliferator-activated receptors: nuclear control of metabolism
-
Desvergne, B. and Wahli, W. (1999) Peroxisome proliferator-activated receptors: nuclear control of metabolism, Endocr Rev 20: 649–688.
-
(1999)
Endocr Rev
, vol.20
, pp. 649-688
-
-
Desvergne, B.1
Wahli, W.2
-
17
-
-
4544275181
-
The endocannabinoid system and its therapeutic exploitation
-
Di, M. et al. (2004) The endocannabinoid system and its therapeutic exploitation, Nat Rev Drug Discov 3: 771–784.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 771-784
-
-
Di, M.1
-
18
-
-
33846933276
-
Comment on “A common genetic variant is associated with adult and childhood obesity
-
Dina, C. et al. (2007) Comment on “A common genetic variant is associated with adult and childhood obesity”, Science 315: 187.
-
(2007)
Science
, vol.315
, pp. 187
-
-
Dina, C.1
-
19
-
-
0034905674
-
Mutational analysis of melanocortin-4 receptor, agouti-related protein, and alpha–melanocyte–stimulating hormone genes in severely obese children
-
Dubern, B. et al. (2001) Mutational analysis of melanocortin-4 receptor, agouti-related protein, and alpha–melanocyte–stimulating hormone genes in severely obese children, J Pediatr 139: 204–209.
-
(2001)
J Pediatr
, vol.139
, pp. 204-209
-
-
Dubern, B.1
-
20
-
-
0036527074
-
Variation in the fatty acid binding protein 2 gene is not associated with markers of metabolic syndrome in patients with coronary heart disease
-
Erkkila, A.T. et al. (2002) Variation in the fatty acid binding protein 2 gene is not associated with markers of metabolic syndrome in patients with coronary heart disease, Nutr Metab Cardiovasc Dis 12: 53–59.
-
(2002)
Nutr Metab Cardiovasc Dis
, vol.12
, pp. 53-59
-
-
Erkkila, A.T.1
-
21
-
-
33746320552
-
Monogenic human obesity syndromes
-
Farooqi, I.S. (2006) Monogenic human obesity syndromes, Prog Brain Res 153: 119–125.
-
(2006)
Prog Brain Res
, vol.153
, pp. 119-125
-
-
Farooqi, I.S.1
-
22
-
-
0037456768
-
Clinical Spectrum of Obesity and Mutations in the Melanocortin 4 Receptor Gene
-
Farooqi, I.S. et al. (2003) Clinical Spectrum of Obesity and Mutations in the Melanocortin 4 Receptor Gene, N Engl J Med 348: 1085.
-
(2003)
N Engl J Med
, vol.348
, pp. 1085
-
-
Farooqi, I.S.1
-
23
-
-
0037116641
-
Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey
-
Ford, E.S. et al. (2002) Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey, J Am Med Assoc 287: 356–359.
-
(2002)
J Am Med Assoc
, vol.287
, pp. 356-359
-
-
Ford, E.S.1
-
24
-
-
33144478823
-
Peroxisomal proliferator activated receptor–gamma deficiency in a Canadian kindred with familial partial lipodystrophy type 3 (FPLD3), BMC
-
Francis, G.A. et al. (2006) Peroxisomal proliferator activated receptor–gamma deficiency in a Canadian kindred with familial partial lipodystrophy type 3 (FPLD3), BMC Med Genet 7: 3.
-
(2006)
Med Genet
, vol.7
, pp. 3
-
-
Francis, G.A.1
-
25
-
-
33846312172
-
Mitochondrial DNA Depletion in Small– and Large–for–Gestational– Age Newborns
-
Silver Spring
-
Gemma, C. et al. (2006) Mitochondrial DNA Depletion in Small– and Large–for–Gestational– Age Newborns, Obesity (Silver Spring) 14: 2193–2199.
-
(2006)
Obesity
, vol.14
, pp. 2193-2199
-
-
Gemma, C.1
-
26
-
-
15944411012
-
Polymorphisms in the fatty acid–binding protein 2 and apolipoprotein C-III genes are associated with the metabolic syndrome and dyslipidemia in a South Indian population
-
Guettier, J.M. et al. (2005) Polymorphisms in the fatty acid–binding protein 2 and apolipoprotein C-III genes are associated with the metabolic syndrome and dyslipidemia in a South Indian population, J Clin Endocrinol Metab 90: 1705–1711.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 1705-1711
-
-
Guettier, J.M.1
-
27
-
-
33845615814
-
Serotonin and norepinephrine reuptake inhibition and eating behavior
-
Hainer, V. et al. (2006) Serotonin and norepinephrine reuptake inhibition and eating behavior, Ann NY Acad Sci 1083: 252–269.
-
(2006)
Ann NY Acad Sci
, vol.1083
, pp. 252-269
-
-
Hainer, V.1
-
28
-
-
0035213101
-
Monogenic dyslipidemias: window on determinants of plasma lipoprotein metabolism
-
Hegele, R.A. (2001) Monogenic dyslipidemias: window on determinants of plasma lipoprotein metabolism, Am J Hum Genet 69: 1161–1177.
-
(2001)
Am J Hum Genet
, vol.69
, pp. 1161-1177
-
-
Hegele, R.A.1
-
29
-
-
23944501014
-
Genetic and physiological insights into the metabolic syndrome, Am J Physiol
-
Hegele, R.A. (2005) Genetic and physiological insights into the metabolic syndrome, Am J Physiol Regul Integr Comp Physiol 289: R663–R669.
-
(2005)
Regul Integr Comp Physiol
, vol.289
, pp. R663-R669
-
-
Hegele, R.A.1
-
30
-
-
0034974846
-
Common genomic variation in LMNA modulates indexes of obesity in Inuit
-
Hegele, R.A. et al. (2001) Common genomic variation in LMNA modulates indexes of obesity in Inuit, J Clin Endocrinol Metab 86: 2747–2751.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 2747-2751
-
-
Hegele, R.A.1
-
31
-
-
0029895783
-
Allelic variation of human serotonin transporter gene expression
-
Heils, A. et al. (1996) Allelic variation of human serotonin transporter gene expression, J Neurochem 66: 2621–2624.
-
(1996)
J Neurochem
, vol.66
, pp. 2621-2624
-
-
Heils, A.1
-
32
-
-
33645825830
-
A common genetic variant is associated with adult and childhood obesity
-
Herbert, A. et al. (2006) A common genetic variant is associated with adult and childhood obesity, Science 312: 279–283.
-
(2006)
Science
, vol.312
, pp. 279-283
-
-
Herbert, A.1
-
33
-
-
0346880504
-
Inflammatory pathways and insulin action
-
Hotamisligil, G.S. (2003) Inflammatory pathways and insulin action, Int J Obes Relat Metab Disord 27(Suppl 3): S53–S55.
-
(2003)
Int J Obes Relat Metab Disord
, vol.27
, Issue.3
, pp. S53-S55
-
-
Hotamisligil, G.S.1
-
34
-
-
33845866857
-
Inflammation and metabolic disorders
-
Hotamisligil, G.S. (2006) Inflammation and metabolic disorders, Nature 444: 860–867.
-
(2006)
Nature
, vol.444
, pp. 860-867
-
-
Hotamisligil, G.S.1
-
35
-
-
34247193564
-
Metabolic syndrome: is it a syndrome? Does it matter?
-
Kahn, R. (2007) Metabolic syndrome: is it a syndrome? Does it matter? Circulation 115: 1806–1810.
-
(2007)
Circulation
, vol.115
, pp. 1806-1810
-
-
Kahn, R.1
-
36
-
-
33845603028
-
Fetal origins of stress-related adult disease
-
Kajantie, E. (2006) Fetal origins of stress-related adult disease, Ann NY Acad Sci 1083: 11–27.
-
(2006)
Ann NY Acad Sci
, vol.1083
, pp. 11-27
-
-
Kajantie, E.1
-
37
-
-
0036788293
-
Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
-
Kelley, D.E. et al. (2002) Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes, Diabetes 51: 2944–2950.
-
(2002)
Diabetes
, vol.51
, pp. 2944-2950
-
-
Kelley, D.E.1
-
38
-
-
14344273991
-
Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome
-
Kissebah, A.H. et al. (2000) Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome, Proc Natl Acad Sci USA 97: 14478–14483.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 14478-14483
-
-
Kissebah, A.H.1
-
39
-
-
33845656373
-
The endocannabinoid system as a target for the treatment of visceral obesity and metabolic syndrome
-
Kyrou, I. et al. (2006) The endocannabinoid system as a target for the treatment of visceral obesity and metabolic syndrome, Ann NY Acad Sci 1083: 270–305.
-
(2006)
Ann NY Acad Sci
, vol.1083
, pp. 270-305
-
-
Kyrou, I.1
-
40
-
-
12144288056
-
Linkage of the metabolic syndrome to 1q23–q31 in Hispanic families: the Insulin Resistance Atherosclerosis Study Family Study
-
Langefeld, C.D. et al. (2004) Linkage of the metabolic syndrome to 1q23–q31 in Hispanic families: the Insulin Resistance Atherosclerosis Study Family Study, Diabetes 53: 1170–1174.
-
(2004)
Diabetes
, vol.53
, pp. 1170-1174
-
-
Langefeld, C.D.1
-
41
-
-
22044448247
-
Mitochondria-based model for fetal origin of adult disease and insulin resistance
-
Lee, H.K. et al. (2005) Mitochondria-based model for fetal origin of adult disease and insulin resistance, Ann NY Acad Sci 1042: 1–18.
-
(2005)
Ann NY Acad Sci
, vol.1042
, pp. 1-18
-
-
Lee, H.K.1
-
42
-
-
0036595706
-
ACE gene insertion / deletion polymorphism associated with 1998 World Health Organization definition of metabolic syndrome in Chinese type 2 diabetic patients
-
Lee, Y.J. and Tsai, J.C. (2002) ACE gene insertion / deletion polymorphism associated with 1998 World Health Organization definition of metabolic syndrome in Chinese type 2 diabetic patients, Diabetes Care 25: 1002–1008.
-
(2002)
Diabetes Care
, vol.25
, pp. 1002-1008
-
-
Lee, Y.J.1
Tsai, J.C.2
-
43
-
-
0346101835
-
Genome-wide linkage scan for the metabolic syndrome in the HERITAGE Family Study
-
Loos, R.J. et al. (2003) Genome-wide linkage scan for the metabolic syndrome in the HERITAGE Family Study, J Clin Endocrinol Metab 88: 5935–5943.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 5935-5943
-
-
Loos, R.J.1
-
44
-
-
33846933276
-
Comment on “A common genetic variant is associated with adult and childhood obesity
-
Loos, R.J. et al. (2007) Comment on “A common genetic variant is associated with adult and childhood obesity”, Science 315: 187.
-
(2007)
Science
, vol.315
, pp. 187
-
-
Loos, R.J.1
-
45
-
-
3543106033
-
Genome-wide identification of genes likely to be involved in human genetic disease
-
Lopez-Bigas, N. and Ouzounis, C.A. (2004) Genome-wide identification of genes likely to be involved in human genetic disease, Nucleic Acids Res 32: 3108–3114.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 3108-3114
-
-
Lopez-Bigas, N.1
Ouzounis, C.A.2
-
46
-
-
33847656105
-
LRP 6 mutation in a family with early coronary disease and metabolic risk factors
-
Mani, A. et al. (2007) LRP 6 mutation in a family with early coronary disease and metabolic risk factors. Science 315: 126–128.
-
(2007)
Science
, vol.315
, pp. 126-128
-
-
Mani, A.1
-
47
-
-
1642268936
-
Contribution of APOA 5 gene variants to plasma triglyceride determination and to the response to both fat and glucose tolerance challenges
-
Martin, S., Nicaud, V. et al. (2003) Contribution of APOA 5 gene variants to plasma triglyceride determination and to the response to both fat and glucose tolerance challenges, Biochim Biophys Acta 1637: 217–225.
-
(2003)
Biochim Biophys Acta
, vol.1637
, pp. 217-225
-
-
Martin, S.1
Nicaud, V.2
-
48
-
-
24644470933
-
Selection of candidate genes in hypertension, Methods
-
Mein, C.A. et al. (2005) Selection of candidate genes in hypertension, Methods Mol Med 108: 107–129.
-
(2005)
Mol Med
, vol.108
, pp. 107-129
-
-
Mein, C.A.1
-
49
-
-
26244448109
-
Lack of association between certain candidate gene polymorphisms and the metabolic syndrome
-
Meirhaeghe, A. et al. (2005) Lack of association between certain candidate gene polymorphisms and the metabolic syndrome, Mol Genet Metab 86: 293–299.
-
(2005)
Mol Genet Metab
, vol.86
, pp. 293-299
-
-
Meirhaeghe, A.1
-
50
-
-
34047135689
-
APOC 3 promoter polymorphisms C-482T and T-455C are associated with the metabolic syndrome
-
Miller, M. et al. (2007) APOC 3 promoter polymorphisms C-482T and T-455C are associated with the metabolic syndrome, Arch Med Res 38: 444–451.
-
(2007)
Arch Med Res
, vol.38
, pp. 444-451
-
-
Miller, M.1
-
51
-
-
0038054341
-
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
Mootha, V.K. et al. (2003) PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes, Nat Genet 34: 267–273.
-
(2003)
Nat Genet
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
-
52
-
-
33947586983
-
No evidence for an involvement of variants in the cannabinoid receptor gene (CNR1) in obesity in German children and adolescents
-
Muller, T.D. et al. (2007) No evidence for an involvement of variants in the cannabinoid receptor gene (CNR1) in obesity in German children and adolescents, Mol Genet Metab 90: 429–434.
-
(2007)
Mol Genet Metab
, vol.90
, pp. 429-434
-
-
Muller, T.D.1
-
53
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Multiple authors
-
Multiple authors (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls, Nature 447: 661–678.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
54
-
-
33845319469
-
Unraveling the genetics of human obesity
-
Mutch, D.M. and Clement, K. (2006) Unraveling the genetics of human obesity, PLoS Genet 2: e188.
-
(2006)
PLoS Genet
, vol.2
, pp. e188
-
-
Mutch, D.M.1
Clement, K.2
-
55
-
-
34250826679
-
Rosiglitazone and Cardiotoxicity – Weighing the Evidence
-
Nathan, D.M. (2007) Rosiglitazone and Cardiotoxicity – Weighing the Evidence, N Engl J Med.
-
(2007)
N Engl J Med.
-
-
Nathan, D.M.1
-
56
-
-
0035897696
-
Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)
-
Ncep. (2001) Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III), J Am Med Assoc 285: 2486–2497.
-
(2001)
J Am Med Assoc
, vol.285
, pp. 2486-2497
-
-
Ncep1
-
57
-
-
0034668205
-
Role of the peroxisome proliferator-activated receptors (PPAR) in atherosclerosis
-
Neve, B.P. et al. (2000) Role of the peroxisome proliferator-activated receptors (PPAR) in atherosclerosis, Biochem Pharmacol 60: 1245–1250.
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 1245-1250
-
-
Neve, B.P.1
-
58
-
-
34147125312
-
Defective mitochondrial biogenesis: a hallmark of the high cardiovascular risk in the metabolic syndrome?
-
Nisoli, E. et al. (2007) Defective mitochondrial biogenesis: a hallmark of the high cardiovascular risk in the metabolic syndrome? Circ Res 100: 795–806.
-
(2007)
Circ Res
, vol.100
, pp. 795-806
-
-
Nisoli, E.1
-
59
-
-
9144226803
-
Apolipoprotein C-III, metabolic syndrome, and risk of coronary artery disease
-
Olivieri, O. et al. (2003) Apolipoprotein C-III, metabolic syndrome, and risk of coronary artery disease, J Lipid Res 44: 2374–2381.
-
(2003)
J Lipid Res
, vol.44
, pp. 2374-2381
-
-
Olivieri, O.1
-
60
-
-
0033862078
-
Role of tumor necrosis factor-alpha gene locus in obesity and obesity-associated hypertension in French Canadians
-
Pausova, Z. et al. (2000) Role of tumor necrosis factor-alpha gene locus in obesity and obesity-associated hypertension in French Canadians, Hypertension 36: 14–19.
-
(2000)
Hypertension
, vol.36
, pp. 14-19
-
-
Pausova, Z.1
-
61
-
-
0036649742
-
Association of genes to genetically inherited diseases using data mining
-
Perez-Iratxeta, C. et al. (2002) Association of genes to genetically inherited diseases using data mining, Nat Genet 31: 316–319.
-
(2002)
Nat Genet
, vol.31
, pp. 316-319
-
-
Perez-Iratxeta, C.1
-
62
-
-
28344451684
-
Metabolic syndrome in aboriginal Canadians: prevalence and genetic associations
-
Pollex, R.L. et al. (2006) Metabolic syndrome in aboriginal Canadians: prevalence and genetic associations, Atherosclerosis 184: 121–129.
-
(2006)
Atherosclerosis
, vol.184
, pp. 121-129
-
-
Pollex, R.L.1
-
63
-
-
27844525503
-
Monogenic syndromes of abnormal glucose homeostasis: clinical review and relevance to the understanding of the pathology of insulin resistance and beta cell failure
-
Porter, J.R. and Barrett, T.G. (2005) Monogenic syndromes of abnormal glucose homeostasis: clinical review and relevance to the understanding of the pathology of insulin resistance and beta cell failure, J Med Genet 42: 893–902.
-
(2005)
J Med Genet
, vol.42
, pp. 893-902
-
-
Porter, J.R.1
Barrett, T.G.2
-
64
-
-
34247867956
-
Molecular genetics of experimental hypertension and the metabolic syndrome: from gene pathways to new therapies
-
Pravenec, M. and Kurtz, T.W. (2007) Molecular genetics of experimental hypertension and the metabolic syndrome: from gene pathways to new therapies, Hypertension 49: 941–952.
-
(2007)
Hypertension
, vol.49
, pp. 941-952
-
-
Pravenec, M.1
Kurtz, T.W.2
-
65
-
-
33751329250
-
Global variation in copy number in the human genome
-
Redon, R. et al. (2006) Global variation in copy number in the human genome, Nature 444: 444–454.
-
(2006)
Nature
, vol.444
, pp. 444-454
-
-
Redon, R.1
-
66
-
-
34347273447
-
Genetic Variations at the Endocannabinoid Type 1 Receptor Gene (CNR1) Are Associated with Obesity Phenotypes in Men
-
Russo, P. et al. (2007) Genetic Variations at the Endocannabinoid Type 1 Receptor Gene (CNR1) Are Associated with Obesity Phenotypes in Men, J Clin Endocrinol Metab 92: 2382–2386.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 2382-2386
-
-
Russo, P.1
-
67
-
-
34249888775
-
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
-
Saxena, R. et al. (2007) Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels, Science 316: 1331–1336.
-
(2007)
Science
, vol.316
, pp. 1331-1336
-
-
Saxena, R.1
-
68
-
-
0029791412
-
PPARalpha and PPARgamma activators direct a distinct tissuespecific transcriptional response via a PPRE in the lipoprotein lipase gene
-
Schoonjans, K. et al. (1996) PPARalpha and PPARgamma activators direct a distinct tissuespecific transcriptional response via a PPRE in the lipoprotein lipase gene, EMBO J 15: 5336–5348.
-
(1996)
EMBO J
, vol.15
, pp. 5336-5348
-
-
Schoonjans, K.1
-
69
-
-
33644672013
-
Molecular characterization of new selective peroxisome proliferator-activated receptor gamma modulators with angiotensin receptor blocking activity
-
Schupp, M. et al. (2005) Molecular characterization of new selective peroxisome proliferator-activated receptor gamma modulators with angiotensin receptor blocking activity, Diabetes 54: 3442–3452.
-
(2005)
Diabetes
, vol.54
, pp. 3442-3452
-
-
Schupp, M.1
-
70
-
-
34249885875
-
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
-
Scott, L.J. et al. (2007) A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants, Science 316: 1341–1345.
-
(2007)
Science
, vol.316
, pp. 1341-1345
-
-
Scott, L.J.1
-
71
-
-
0036557426
-
Molecular etiologies of MODY and other early-onset forms of diabetes
-
Shih, D.Q. and Stoffel, M. (2002) Molecular etiologies of MODY and other early-onset forms of diabetes, Curr Diab Rep 2: 125–134.
-
(2002)
Curr Diab Rep
, vol.2
, pp. 125-134
-
-
Shih, D.Q.1
Stoffel, M.2
-
72
-
-
14544299691
-
G protein polymorphisms in hypertension, atherosclerosis, and diabetes
-
Siffert, W. (2005) G protein polymorphisms in hypertension, atherosclerosis, and diabetes, Annu Rev Med 56: 17–28.
-
(2005)
Annu Rev Med
, vol.56
, pp. 17-28
-
-
Siffert, W.1
-
73
-
-
35648971173
-
INSIG 2 gene polymorphism is not associated with obesity in Caucasian, Afro-Caribbean and Indian subjects
-
Lond
-
Smith, A.J. et al. (2007) INSIG 2 gene polymorphism is not associated with obesity in Caucasian, Afro-Caribbean and Indian subjects, Int J Obes (Lond).
-
(2007)
Int J Obes
-
-
Smith, A.J.1
-
74
-
-
2942698938
-
A novel pathway to the manifestations of metabolic syndrome
-
Sonnenberg, G.E. et al. (2004) A novel pathway to the manifestations of metabolic syndrome, Obes Res 12: 180–186.
-
(2004)
Obes Res
, vol.12
, pp. 180-186
-
-
Sonnenberg, G.E.1
-
75
-
-
27644450194
-
Peroxisome proliferator-activated receptor gamma and its coactivator-1 alpha may be associated with features of the metabolic syndrome in adolescents
-
Sookoian, S. et al. (2005 a) Peroxisome proliferator-activated receptor gamma and its coactivator-1 alpha may be associated with features of the metabolic syndrome in adolescents, J Mol Endocrinol 35: 373–380.
-
(2005)
J Mol Endocrinol
, vol.35
, pp. 373-380
-
-
Sookoian, S.1
-
76
-
-
25844473422
-
The G-308A promoter variant of the tumor necrosis factor-alpha gene is associated with hypertension in adolescents harboring the metabolic syndrome
-
Sookoian, S. et al. (2005 b) The G-308A promoter variant of the tumor necrosis factor-alpha gene is associated with hypertension in adolescents harboring the metabolic syndrome, Am J Hypertens 18: 1271–1275.
-
(2005)
Am J Hypertens
, vol.18
, pp. 1271-1275
-
-
Sookoian, S.1
-
77
-
-
33645059736
-
Meta-analysis on the G-308A tumor necrosis factor alpha gene variant and phenotypes associated with the metabolic syndrome
-
Sookoian, S. et al. (2005 c) Meta-analysis on the G-308A tumor necrosis factor alpha gene variant and phenotypes associated with the metabolic syndrome, Obes Res 13: 2122–2131.
-
(2005)
Obes Res
, vol.13
, pp. 2122-2131
-
-
Sookoian, S.1
-
78
-
-
33947121582
-
Short allele of serotonin transporter gene promoter is a risk factor for obesity in adolescents
-
Silver Spring
-
Sookoian, S. et al. (2007) Short allele of serotonin transporter gene promoter is a risk factor for obesity in adolescents, Obesity (Silver Spring) 15: 271–276.
-
(2007)
Obesity
, pp. 15-276
-
-
Sookoian, S.1
-
79
-
-
33750262366
-
Effect of gene polymorphisms on lipoprotein levels in patients with dyslipidemia of metabolic syndrome
-
Stancakova, A. et al. (2006) Effect of gene polymorphisms on lipoprotein levels in patients with dyslipidemia of metabolic syndrome, Physiol Res 55: 483–490.
-
(2006)
Physiol Res
, vol.55
, pp. 483-490
-
-
Stancakova, A.1
-
80
-
-
0034098728
-
New target regions for human hypertension via comparative genomics
-
Stoll, M. et al. (2000) New target regions for human hypertension via comparative genomics, Genome Res 10: 473–482.
-
(2000)
Genome Res
, vol.10
, pp. 473-482
-
-
Stoll, M.1
-
81
-
-
26844431513
-
Dual and pan-peroxisome proliferator-activated receptors (PPAR) co-agonism: the bezafibrate lessons
-
Tenenbaum, A. et al. (2005) Dual and pan-peroxisome proliferator-activated receptors (PPAR) co-agonism: the bezafibrate lessons, Cardiovasc Diabetol 4: 14.
-
(2005)
Cardiovasc Diabetol
, vol.4
, pp. 14
-
-
Tenenbaum, A.1
-
82
-
-
20844461135
-
Obesity and metabolic syndrome in circadian Clock mutant mice
-
Turek, F.W. et al. (2005) Obesity and metabolic syndrome in circadian Clock mutant mice, Science 308: 1043–1045.
-
(2005)
Science
, vol.308
, pp. 1043-1045
-
-
Turek, F.W.1
-
83
-
-
23144443079
-
GeneSeeker: extraction and integration of human disease-related information from web-based genetic databases
-
van Driel, M.A. et al. (2005) GeneSeeker: extraction and integration of human disease-related information from web-based genetic databases, Nucleic Acids Res 33: W758–W761.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. W758-W761
-
-
van Driel, M.A.1
-
84
-
-
33747133646
-
Thr 54 allele carriers of the Ala54Thr variant of FABP 2 gene have associations with metabolic syndrome and hypertriglyceridemia in urban South Indians
-
Vimaleswaran, K.S. et al. (2006) Thr 54 allele carriers of the Ala54Thr variant of FABP 2 gene have associations with metabolic syndrome and hypertriglyceridemia in urban South Indians, Metabolism 55: 1222–1226.
-
(2006)
Metabolism
, vol.55
, pp. 1222-1226
-
-
Vimaleswaran, K.S.1
-
85
-
-
2542548063
-
Obesity and the metabolic syndrome in children and adolescents
-
Weiss, R. et al. (2004) Obesity and the metabolic syndrome in children and adolescents, N Engl J Med 350: 2362–2374.
-
(2004)
N Engl J Med
, vol.350
, pp. 2362-2374
-
-
Weiss, R.1
-
86
-
-
1642325814
-
Association of GNB 3 gene with pulse pressure and clustering of risk factors for cardiovascular disease in Japanese
-
Yamamoto, M. et al. (2004) Association of GNB 3 gene with pulse pressure and clustering of risk factors for cardiovascular disease in Japanese, Biochem Biophys Res Commun 316: 744–748.
-
(2004)
Biochem Biophys Res Commun
, vol.316
, pp. 744-748
-
-
Yamamoto, M.1
-
87
-
-
33845655497
-
Targeting components of the stress system as potential therapies for the metabolic syndrome: the peroxisome proliferator-activated receptors
-
Yumuk, V.D. (2006) Targeting components of the stress system as potential therapies for the metabolic syndrome: the peroxisome proliferator-activated receptors, Ann NY Acad Sci 1083: 306–318.
-
(2006)
Ann NY Acad Sci
, vol.1083
, pp. 306-318
-
-
Yumuk, V.D.1
-
88
-
-
34249895023
-
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
-
Zeggini, E. et al. (2007) Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes, Science 316: 1336–1341.
-
(2007)
Science
, vol.316
, pp. 1336-1341
-
-
Zeggini, E.1
|