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Volumn 9, Issue 1, 2009, Pages 134-143

Decreased severity of experimental autoimmune encephalomyelitis during resveratrol administration is associated with increased IL-17+IL-10+ T cells, CD4- IFN-γ+ cells, and decreased macrophage IL-6 expression

Author keywords

Cytokines; EAE; Macrophages; Resveratrol; T cells

Indexed keywords

CD4 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12P35; INTERLEUKIN 17; INTERLEUKIN 23P19; INTERLEUKIN 6; RESVERATROL;

EID: 58149461554     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2008.10.015     Document Type: Article
Times cited : (94)

References (79)
  • 1
    • 0036892580 scopus 로고    scopus 로고
    • Matrix metalloproteinases and neuroinflammation in multiple sclerosis
    • Rosenberg G.A. Matrix metalloproteinases and neuroinflammation in multiple sclerosis. Neuroscientist 8 6 (2002) 586-595
    • (2002) Neuroscientist , vol.8 , Issue.6 , pp. 586-595
    • Rosenberg, G.A.1
  • 2
    • 0023522632 scopus 로고
    • T cells in multiple sclerosis and inflammatory central nervous system diseases
    • Hafler D.A., and Weiner H.L. T cells in multiple sclerosis and inflammatory central nervous system diseases. Immunol Rev 100 (1987) 307-332
    • (1987) Immunol Rev , vol.100 , pp. 307-332
    • Hafler, D.A.1    Weiner, H.L.2
  • 3
    • 0036071556 scopus 로고    scopus 로고
    • The worldwide prevalence of multiple sclerosis
    • Pugliatti M., Sotgiu S., and Rosati G. The worldwide prevalence of multiple sclerosis. Clin Neurol Neurosurg 104 3 (2002) 182-191
    • (2002) Clin Neurol Neurosurg , vol.104 , Issue.3 , pp. 182-191
    • Pugliatti, M.1    Sotgiu, S.2    Rosati, G.3
  • 5
    • 35649010838 scopus 로고    scopus 로고
    • Persistent activation of microglia is associated with neuronal dysfunction of callosal projecting pathways and multiple sclerosis-like lesions in relapsing-remitting experimental autoimmune encephalomyelitis
    • Rasmussen S., Wang Y., Kivisakk P., Bronson R.T., Meyer M., Imitola J., et al. Persistent activation of microglia is associated with neuronal dysfunction of callosal projecting pathways and multiple sclerosis-like lesions in relapsing-remitting experimental autoimmune encephalomyelitis. Brain 130 Pt 11 (2007) 2816-2829
    • (2007) Brain , vol.130 , Issue.PART 11 , pp. 2816-2829
    • Rasmussen, S.1    Wang, Y.2    Kivisakk, P.3    Bronson, R.T.4    Meyer, M.5    Imitola, J.6
  • 6
    • 0032524181 scopus 로고    scopus 로고
    • ELI-spot of Th-1 cytokine secreting PBMC's in multiple sclerosis: correlation with MRI lesions
    • Calabresi P.A., Fields N.S., Farnon E.C., Frank J.A., Bash C.N., Kawanashi T., et al. ELI-spot of Th-1 cytokine secreting PBMC's in multiple sclerosis: correlation with MRI lesions. J Neuroimmunol 85 2 (1998) 212-219
    • (1998) J Neuroimmunol , vol.85 , Issue.2 , pp. 212-219
    • Calabresi, P.A.1    Fields, N.S.2    Farnon, E.C.3    Frank, J.A.4    Bash, C.N.5    Kawanashi, T.6
  • 7
    • 0034634740 scopus 로고    scopus 로고
    • Interleukin-6 expression in human multiple sclerosis lesions
    • Schonrock L.M., Gawlowski G., and Brück W. Interleukin-6 expression in human multiple sclerosis lesions. Neurosci Lett 294 1 (2000) 45-48
    • (2000) Neurosci Lett , vol.294 , Issue.1 , pp. 45-48
    • Schonrock, L.M.1    Gawlowski, G.2    Brück, W.3
  • 8
    • 33744936550 scopus 로고    scopus 로고
    • IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production
    • Vaknin-Dembinsky A., Balashov K., and Weiner H.L. IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production. J Immunol 176 12 (2006) 7768-7774
    • (2006) J Immunol , vol.176 , Issue.12 , pp. 7768-7774
    • Vaknin-Dembinsky, A.1    Balashov, K.2    Weiner, H.L.3
  • 9
    • 33846593869 scopus 로고    scopus 로고
    • Increased IL-23p19 expression in multiple sclerosis lesions and its induction in microglia
    • Li Y., Chu N., Hu A., Gran B., Rostami A., and Zhang G.-X. Increased IL-23p19 expression in multiple sclerosis lesions and its induction in microglia. Brain 130 2 (2007) 490-501
    • (2007) Brain , vol.130 , Issue.2 , pp. 490-501
    • Li, Y.1    Chu, N.2    Hu, A.3    Gran, B.4    Rostami, A.5    Zhang, G.-X.6
  • 10
    • 0344389016 scopus 로고    scopus 로고
    • Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis
    • Matusevicius D., Kivisakk P., He B., Kostulas N., Ozenci V., Fredrikson S., et al. Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis. Mult Scler 5 2 (1999) 101-104
    • (1999) Mult Scler , vol.5 , Issue.2 , pp. 101-104
    • Matusevicius, D.1    Kivisakk, P.2    He, B.3    Kostulas, N.4    Ozenci, V.5    Fredrikson, S.6
  • 11
    • 0036105484 scopus 로고    scopus 로고
    • Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis
    • Lock C., Hermans G., Pedotti R., Brendolan A., Schadt E., Garren H., et al. Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. Nat Med 8 5 (2002) 500-508
    • (2002) Nat Med , vol.8 , Issue.5 , pp. 500-508
    • Lock, C.1    Hermans, G.2    Pedotti, R.3    Brendolan, A.4    Schadt, E.5    Garren, H.6
  • 12
    • 0037114150 scopus 로고    scopus 로고
    • IL-12p35-deficient mice are susceptible to experimental autoimmune encephalomyelitis: evidence for redundancy in the IL-12 system in the induction of central nervous system autoimmune demyelination
    • Gran B., Zhang G.X., Yu S., Li J., Chen X.H., Ventura E.S., et al. IL-12p35-deficient mice are susceptible to experimental autoimmune encephalomyelitis: evidence for redundancy in the IL-12 system in the induction of central nervous system autoimmune demyelination. J Immunol 169 12 (2002) 7104-7110
    • (2002) J Immunol , vol.169 , Issue.12 , pp. 7104-7110
    • Gran, B.1    Zhang, G.X.2    Yu, S.3    Li, J.4    Chen, X.H.5    Ventura, E.S.6
  • 13
    • 10644294508 scopus 로고    scopus 로고
    • Role of the IL-12/IL-23 system in the regulation of T-cell responses in central nervous system inflammatory demyelination
    • Gran B., Zhang G.X., and Rostami A. Role of the IL-12/IL-23 system in the regulation of T-cell responses in central nervous system inflammatory demyelination. Crit Rev Immunol 24 2 (2004) 111-128
    • (2004) Crit Rev Immunol , vol.24 , Issue.2 , pp. 111-128
    • Gran, B.1    Zhang, G.X.2    Rostami, A.3
  • 14
    • 0347357773 scopus 로고    scopus 로고
    • IL-23 produced by CNS-resident cells controls T cell encephalitogenicity during the effector phase of experimental autoimmune encephalomyelitis
    • Becher B., Durell B.G., and Noelle R.J. IL-23 produced by CNS-resident cells controls T cell encephalitogenicity during the effector phase of experimental autoimmune encephalomyelitis. J Clin Invest 112 8 (2003) 1186-1191
    • (2003) J Clin Invest , vol.112 , Issue.8 , pp. 1186-1191
    • Becher, B.1    Durell, B.G.2    Noelle, R.J.3
  • 15
    • 0032534730 scopus 로고    scopus 로고
    • IL-6-deficient mice are resistant to experimental autoimmune encephalomyelitis: roles of IL-6 in the activation and differentiation of autoreactive T cells
    • Samoilova E.B., Horton J.L., Hilliard B., Liu T.-S.T., and Chen Y. IL-6-deficient mice are resistant to experimental autoimmune encephalomyelitis: roles of IL-6 in the activation and differentiation of autoreactive T cells. J Immunol 161 12 (1998) 6480-6486
    • (1998) J Immunol , vol.161 , Issue.12 , pp. 6480-6486
    • Samoilova, E.B.1    Horton, J.L.2    Hilliard, B.3    Liu, T.-S.T.4    Chen, Y.5
  • 16
    • 33745321276 scopus 로고    scopus 로고
    • IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis
    • Komiyama Y., Nakae S., Matsuki T., Nambu A., Ishigame H., Kakuta S., et al. IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis. J Immunol 177 1 (2006) 566-573
    • (2006) J Immunol , vol.177 , Issue.1 , pp. 566-573
    • Komiyama, Y.1    Nakae, S.2    Matsuki, T.3    Nambu, A.4    Ishigame, H.5    Kakuta, S.6
  • 17
    • 0033765333 scopus 로고    scopus 로고
    • Interleukin-17 and CD40-ligand synergistically enhance cytokine and chemokine production by renal epithelial cells
    • Woltman A.M., de Haij S., Boonstra J.G., Gobin S.J., Daha M.R., and van Kooten C. Interleukin-17 and CD40-ligand synergistically enhance cytokine and chemokine production by renal epithelial cells. J Am Soc Nephrol 11 11 (2000) 2044-2055
    • (2000) J Am Soc Nephrol , vol.11 , Issue.11 , pp. 2044-2055
    • Woltman, A.M.1    de Haij, S.2    Boonstra, J.G.3    Gobin, S.J.4    Daha, M.R.5    van Kooten, C.6
  • 18
    • 34948909646 scopus 로고    scopus 로고
    • Human T(H)17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation
    • Kebir H., Kreymborg K., Ifergan I., Dodelet-Devillers A., Cayrol R., Bernard M., et al. Human T(H)17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation. Nat Med 13 10 (2007) 1173-1175
    • (2007) Nat Med , vol.13 , Issue.10 , pp. 1173-1175
    • Kebir, H.1    Kreymborg, K.2    Ifergan, I.3    Dodelet-Devillers, A.4    Cayrol, R.5    Bernard, M.6
  • 19
    • 0141481855 scopus 로고    scopus 로고
    • Functional assay for human CD4+CD25+ Treg cells reveals an age-dependent loss of suppressive activity
    • Tsaknaridis L., Spencer L., Culbertson N., Hicks K., LaTocha D., Chou Y.K., et al. Functional assay for human CD4+CD25+ Treg cells reveals an age-dependent loss of suppressive activity. J Neurosci Res 74 2 (2003) 296-308
    • (2003) J Neurosci Res , vol.74 , Issue.2 , pp. 296-308
    • Tsaknaridis, L.1    Spencer, L.2    Culbertson, N.3    Hicks, K.4    LaTocha, D.5    Chou, Y.K.6
  • 20
    • 0029555301 scopus 로고
    • Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor
    • Yao Z., Fanslow W.C., Seldin M.F., Rousseau A.-M., Painter S.L., Comeau M.R., et al. Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor. Immunity 3 6 (1995) 811-821
    • (1995) Immunity , vol.3 , Issue.6 , pp. 811-821
    • Yao, Z.1    Fanslow, W.C.2    Seldin, M.F.3    Rousseau, A.-M.4    Painter, S.L.5    Comeau, M.R.6
  • 21
    • 0032055597 scopus 로고    scopus 로고
    • IL-17 stimulates the production and expression of proinflammatory cytokines, IL-{beta} and TNF-{alpha}, by human macrophages
    • Jovanovic D.V., Di Battista J.A., Martel-Pelletier J., Jolicoeur F.C., He Y., Zhang M., et al. IL-17 stimulates the production and expression of proinflammatory cytokines, IL-{beta} and TNF-{alpha}, by human macrophages. J Immunol 160 7 (1998) 3513-3521
    • (1998) J Immunol , vol.160 , Issue.7 , pp. 3513-3521
    • Jovanovic, D.V.1    Di Battista, J.A.2    Martel-Pelletier, J.3    Jolicoeur, F.C.4    He, Y.5    Zhang, M.6
  • 22
    • 41349097097 scopus 로고    scopus 로고
    • STAT1 signaling modulates HIV-1-induced inflammatory responses and leukocyte transmigration across the blood-brain barrier
    • Chaudhuri A., Yang B., Gendelman H.E., Persidsky Y., and Kanmogne G.D. STAT1 signaling modulates HIV-1-induced inflammatory responses and leukocyte transmigration across the blood-brain barrier. Blood 111 4 (2008) 2062-2072
    • (2008) Blood , vol.111 , Issue.4 , pp. 2062-2072
    • Chaudhuri, A.1    Yang, B.2    Gendelman, H.E.3    Persidsky, Y.4    Kanmogne, G.D.5
  • 23
    • 33750936288 scopus 로고    scopus 로고
    • Interleukin-6 facilitates lipopolysaccharide-induced disruption in working memory and expression of other proinflammatory cytokines in hippocampal neuronal cell layers
    • Sparkman N.L., Buchanan J.B., Heyen J.R.R., Chen J., Beverly J.L., and Johnson R.W. Interleukin-6 facilitates lipopolysaccharide-induced disruption in working memory and expression of other proinflammatory cytokines in hippocampal neuronal cell layers. J Neurosci 26 42 (2006) 10709-10716
    • (2006) J Neurosci , vol.26 , Issue.42 , pp. 10709-10716
    • Sparkman, N.L.1    Buchanan, J.B.2    Heyen, J.R.R.3    Chen, J.4    Beverly, J.L.5    Johnson, R.W.6
  • 24
    • 0345189366 scopus 로고    scopus 로고
    • Inflammatory blockade restores adult hippocampal neurogenesis
    • Monje M.L., Toda H., and Palmer T.D. Inflammatory blockade restores adult hippocampal neurogenesis. Science 302 5651 (2003) 1760-1765
    • (2003) Science , vol.302 , Issue.5651 , pp. 1760-1765
    • Monje, M.L.1    Toda, H.2    Palmer, T.D.3
  • 25
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli E., Carrier Y., Gao W., Korn T., Strom T.B., Oukka M., et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441 7090 (2006) 235-238
    • (2006) Nature , vol.441 , Issue.7090 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6
  • 26
    • 33746863277 scopus 로고    scopus 로고
    • T-bet negatively regulates autoimmune myocarditis by suppressing local production of interleukin 17
    • Rangachari M., Mauermann N., Marty R.R., Dirnhofer S., Kurrer M.O., Komnenovic V., et al. T-bet negatively regulates autoimmune myocarditis by suppressing local production of interleukin 17. J Exp Med 203 8 (2006) 2009-2019
    • (2006) J Exp Med , vol.203 , Issue.8 , pp. 2009-2019
    • Rangachari, M.1    Mauermann, N.2    Marty, R.R.3    Dirnhofer, S.4    Kurrer, M.O.5    Komnenovic, V.6
  • 27
    • 33751242743 scopus 로고    scopus 로고
    • Neutralization of IL-17 by active vaccination inhibits IL-23-dependent autoimmune myocarditis
    • Sonderegger I., Rohn T.A., Kurrer M.O., Iezzi G., Zou Y., Kastelein R.A., et al. Neutralization of IL-17 by active vaccination inhibits IL-23-dependent autoimmune myocarditis. Eur J Immunol 36 11 (2006) 2849-2856
    • (2006) Eur J Immunol , vol.36 , Issue.11 , pp. 2849-2856
    • Sonderegger, I.1    Rohn, T.A.2    Kurrer, M.O.3    Iezzi, G.4    Zou, Y.5    Kastelein, R.A.6
  • 28
    • 0346962972 scopus 로고    scopus 로고
    • Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation
    • Murphy C.A., Langrish C.L., Chen Y., Blumenschein W., McClanahan T., Kastelein R.A., et al. Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. J Exp Med 198 12 (2003) 1951-1957
    • (2003) J Exp Med , vol.198 , Issue.12 , pp. 1951-1957
    • Murphy, C.A.1    Langrish, C.L.2    Chen, Y.3    Blumenschein, W.4    McClanahan, T.5    Kastelein, R.A.6
  • 29
    • 33845576001 scopus 로고    scopus 로고
    • Up-regulation of IL-23p19 expression in rheumatoid arthritis synovial fibroblasts by IL-17 through PI3-kinase-, NF-kappaB- and p38 MAPK-dependent signalling pathways
    • Kim H.R., Cho M.L., Kim K.W., Juhn J.Y., Hwang S.Y., Yoon C.H., et al. Up-regulation of IL-23p19 expression in rheumatoid arthritis synovial fibroblasts by IL-17 through PI3-kinase-, NF-kappaB- and p38 MAPK-dependent signalling pathways. Rheumatol (Oxf) 46 1 (2007) 57-64
    • (2007) Rheumatol (Oxf) , vol.46 , Issue.1 , pp. 57-64
    • Kim, H.R.1    Cho, M.L.2    Kim, K.W.3    Juhn, J.Y.4    Hwang, S.Y.5    Yoon, C.H.6
  • 30
    • 0036793842 scopus 로고    scopus 로고
    • The critical role of IL-12p40 in initiating, enhancing, and perpetuating pathogenic events in murine experimental autoimmune neuritis
    • Bao L., Lindgren J.U., van der Meide P., Zhu S., Ljunggren H.G., and Zhu J. The critical role of IL-12p40 in initiating, enhancing, and perpetuating pathogenic events in murine experimental autoimmune neuritis. Brain Pathol 12 4 (2002) 420-429
    • (2002) Brain Pathol , vol.12 , Issue.4 , pp. 420-429
    • Bao, L.1    Lindgren, J.U.2    van der Meide, P.3    Zhu, S.4    Ljunggren, H.G.5    Zhu, J.6
  • 31
    • 0037081793 scopus 로고    scopus 로고
    • Antimicrobial effect of resveratrol on dermatophytes and bacterial pathogens of the skin
    • Chan M.M. Antimicrobial effect of resveratrol on dermatophytes and bacterial pathogens of the skin. Biochem Pharmacol 63 2 (2002) 99-104
    • (2002) Biochem Pharmacol , vol.63 , Issue.2 , pp. 99-104
    • Chan, M.M.1
  • 32
    • 33751072349 scopus 로고    scopus 로고
    • Resveratrol improves health and survival of mice on a high-calorie diet
    • Baur J.A., Pearson K.J., Price N.L., Jamieson H.A., Lerin C., Kalra A., et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444 7117 (2006) 337-342
    • (2006) Nature , vol.444 , Issue.7117 , pp. 337-342
    • Baur, J.A.1    Pearson, K.J.2    Price, N.L.3    Jamieson, H.A.4    Lerin, C.5    Kalra, A.6
  • 33
    • 33750532308 scopus 로고    scopus 로고
    • Regulation of inflammation and redox signaling by dietary polyphenols
    • Rahman I., Biswas S.K., and Kirkham P.A. Regulation of inflammation and redox signaling by dietary polyphenols. Biochem Pharmacol 72 11 (2006) 1439-1452
    • (2006) Biochem Pharmacol , vol.72 , Issue.11 , pp. 1439-1452
    • Rahman, I.1    Biswas, S.K.2    Kirkham, P.A.3
  • 34
    • 33745534542 scopus 로고    scopus 로고
    • The roles of polyphenols in cancer chemoprevention
    • Lee K.W., and Lee H.J. The roles of polyphenols in cancer chemoprevention. Biofactors 26 2 (2006) 105-121
    • (2006) Biofactors , vol.26 , Issue.2 , pp. 105-121
    • Lee, K.W.1    Lee, H.J.2
  • 36
    • 33947127395 scopus 로고    scopus 로고
    • Resveratrol ameliorates experimental autoimmune myocarditis
    • Yoshida Y., Shioi T., and Izumi T. Resveratrol ameliorates experimental autoimmune myocarditis. Circ J 71 3 (2007) 397-404
    • (2007) Circ J , vol.71 , Issue.3 , pp. 397-404
    • Yoshida, Y.1    Shioi, T.2    Izumi, T.3
  • 37
    • 23844523482 scopus 로고    scopus 로고
    • Effect of resveratrol in experimental osteoarthritis in rabbits
    • Elmali N., Esenkaya I., Harma A., Ertem K., Turkoz Y., and Mizrak B. Effect of resveratrol in experimental osteoarthritis in rabbits. Inflamm Res 54 4 (2005) 158-162
    • (2005) Inflamm Res , vol.54 , Issue.4 , pp. 158-162
    • Elmali, N.1    Esenkaya, I.2    Harma, A.3    Ertem, K.4    Turkoz, Y.5    Mizrak, B.6
  • 39
    • 29944444280 scopus 로고    scopus 로고
    • Effect of resveratrol on peritoneal macrophages in rats with severe acute pancreatitis
    • Ma Z.H., Ma Q.Y., Wang L.C., Sha H.C., Wu S.L., and Zhang M. Effect of resveratrol on peritoneal macrophages in rats with severe acute pancreatitis. Inflamm Res 54 12 (2005) 522-527
    • (2005) Inflamm Res , vol.54 , Issue.12 , pp. 522-527
    • Ma, Z.H.1    Ma, Q.Y.2    Wang, L.C.3    Sha, H.C.4    Wu, S.L.5    Zhang, M.6
  • 41
    • 0033129760 scopus 로고    scopus 로고
    • Inhibitory effect of resveratrol on interleukin 6 release by stimulated peritoneal macrophages of mice
    • Zhong M., Cheng G.F., Wang W.J., Guo Y., Zhu X.Y., and Zhang J.T. Inhibitory effect of resveratrol on interleukin 6 release by stimulated peritoneal macrophages of mice. Phytomedicine 6 2 (1999) 79-84
    • (1999) Phytomedicine , vol.6 , Issue.2 , pp. 79-84
    • Zhong, M.1    Cheng, G.F.2    Wang, W.J.3    Guo, Y.4    Zhu, X.Y.5    Zhang, J.T.6
  • 42
    • 0035503936 scopus 로고    scopus 로고
    • Immunomodulatory activity of resveratrol: suppression of lymphocyte proliferation, development of cell-mediated cytotoxicity, and cytokine production
    • Gao X., Xu Y.X., Janakiraman N., Chapman R.A., and Gautam S.C. Immunomodulatory activity of resveratrol: suppression of lymphocyte proliferation, development of cell-mediated cytotoxicity, and cytokine production. Biochem Pharmacol 62 9 (2001) 1299-1308
    • (2001) Biochem Pharmacol , vol.62 , Issue.9 , pp. 1299-1308
    • Gao, X.1    Xu, Y.X.2    Janakiraman, N.3    Chapman, R.A.4    Gautam, S.C.5
  • 43
    • 0242441578 scopus 로고    scopus 로고
    • Inhibition by red wine extract, resveratrol, of cytokine release by alveolar macrophages in COPD
    • Culpitt S.V., Rogers D.F., Fenwick P.S., Shah P., De Matos C., Russell R.E., et al. Inhibition by red wine extract, resveratrol, of cytokine release by alveolar macrophages in COPD. Thorax 58 11 (2003) 942-946
    • (2003) Thorax , vol.58 , Issue.11 , pp. 942-946
    • Culpitt, S.V.1    Rogers, D.F.2    Fenwick, P.S.3    Shah, P.4    De Matos, C.5    Russell, R.E.6
  • 44
    • 36348975230 scopus 로고    scopus 로고
    • Resveratrol (trans-3,5,4'-trihydroxystilbene) ameliorates experimental allergic encephalomyelitis (EAE) primarily via induction of apoptosis in T cells involving activation of AhR and ER
    • Singh N.P., Hegde V., Hofseth L.J., Nagarkatti M., and Nagarkatti P. Resveratrol (trans-3,5,4'-trihydroxystilbene) ameliorates experimental allergic encephalomyelitis (EAE) primarily via induction of apoptosis in T cells involving activation of AhR and ER. Mol Pharmacol 72 6 (2007) 508-521
    • (2007) Mol Pharmacol , vol.72 , Issue.6 , pp. 508-521
    • Singh, N.P.1    Hegde, V.2    Hofseth, L.J.3    Nagarkatti, M.4    Nagarkatti, P.5
  • 45
    • 0027487229 scopus 로고
    • AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet
    • Reeves P.G., Nielsen F.H., and Fahey Jr. G.C. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 123 11 (1993) 1939-1951
    • (1993) J Nutr , vol.123 , Issue.11 , pp. 1939-1951
    • Reeves, P.G.1    Nielsen, F.H.2    Fahey Jr., G.C.3
  • 46
    • 34248647881 scopus 로고    scopus 로고
    • Active induction of experimental allergic encephalomyelitis
    • Stromnes I.M., and Goverman J.M. Active induction of experimental allergic encephalomyelitis. Nat Protoc 1 4 (2006) 1810-1819
    • (2006) Nat Protoc , vol.1 , Issue.4 , pp. 1810-1819
    • Stromnes, I.M.1    Goverman, J.M.2
  • 47
    • 15244341962 scopus 로고    scopus 로고
    • Disparate expression of IL-12 by SJL/J and B10.S macrophages during Theiler's virus infection is associated with activity of TLR7 and mitogen-activated protein kinases
    • Petro T.M. Disparate expression of IL-12 by SJL/J and B10.S macrophages during Theiler's virus infection is associated with activity of TLR7 and mitogen-activated protein kinases. Microbes Infect 7 2 (2005) 224-232
    • (2005) Microbes Infect , vol.7 , Issue.2 , pp. 224-232
    • Petro, T.M.1
  • 48
    • 0025246367 scopus 로고
    • The T lymphocyte in experimental allergic encephalomyelitis
    • Zamvil S.S., and Steinman L. The T lymphocyte in experimental allergic encephalomyelitis. Annu Rev Immunol 8 (1990) 579-621
    • (1990) Annu Rev Immunol , vol.8 , pp. 579-621
    • Zamvil, S.S.1    Steinman, L.2
  • 49
    • 16244417773 scopus 로고    scopus 로고
    • Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis
    • McMahon E.J., Bailey S.L., Castenada C.V., Waldner H., and Miller S.D. Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis. Nat Med 11 3 (2005) 335-339
    • (2005) Nat Med , vol.11 , Issue.3 , pp. 335-339
    • McMahon, E.J.1    Bailey, S.L.2    Castenada, C.V.3    Waldner, H.4    Miller, S.D.5
  • 50
    • 0016787935 scopus 로고
    • Experimental autoimmune encephalomyelitis in mice: immunologic response to mouse spinal cord and myelin basic proteins
    • Bernard C.C., and Carnegie P.R. Experimental autoimmune encephalomyelitis in mice: immunologic response to mouse spinal cord and myelin basic proteins. J Immunol 114 5 (1975) 1537-1540
    • (1975) J Immunol , vol.114 , Issue.5 , pp. 1537-1540
    • Bernard, C.C.1    Carnegie, P.R.2
  • 51
    • 13244283212 scopus 로고    scopus 로고
    • IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
    • Langrish C.L., Chen Y., Blumenschein W.M., Mattson J., Basham B., Sedgwick J.D., et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 201 2 (2005) 233-240
    • (2005) J Exp Med , vol.201 , Issue.2 , pp. 233-240
    • Langrish, C.L.1    Chen, Y.2    Blumenschein, W.M.3    Mattson, J.4    Basham, B.5    Sedgwick, J.D.6
  • 52
    • 46949104323 scopus 로고    scopus 로고
    • IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition
    • Kroenke M.A., Carlson T.J., Andjelkovic A.V., and Segal B.M. IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition. J Exp Med 205 (2008) 1535-1541
    • (2008) J Exp Med , vol.205 , pp. 1535-1541
    • Kroenke, M.A.1    Carlson, T.J.2    Andjelkovic, A.V.3    Segal, B.M.4
  • 53
    • 33847206969 scopus 로고    scopus 로고
    • IL-17 family cytokines and the expanding diversity of effector T cell lineages
    • Weaver C.T., Hatton R.D., Mangan P.R., and Harrington L.E. IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu Rev Immunol 25 1 (2007) 821-852
    • (2007) Annu Rev Immunol , vol.25 , Issue.1 , pp. 821-852
    • Weaver, C.T.1    Hatton, R.D.2    Mangan, P.R.3    Harrington, L.E.4
  • 54
    • 36248965294 scopus 로고    scopus 로고
    • TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology
    • McGeachy M.J., Bak-Jensen K.S., Chen Y., Tato C.M., Blumenschein W., McClanahan T., et al. TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology. Nat Immunol 8 12 (2007) 1390-1397
    • (2007) Nat Immunol , vol.8 , Issue.12 , pp. 1390-1397
    • McGeachy, M.J.1    Bak-Jensen, K.S.2    Chen, Y.3    Tato, C.M.4    Blumenschein, W.5    McClanahan, T.6
  • 55
    • 0025819340 scopus 로고
    • Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers
    • Chan S.H., Perussia B., Gupta J.W., Kobayashi M., Pospisil M., Young H.A., et al. Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers. J Exp Med 173 4 (1991) 869-879
    • (1991) J Exp Med , vol.173 , Issue.4 , pp. 869-879
    • Chan, S.H.1    Perussia, B.2    Gupta, J.W.3    Kobayashi, M.4    Pospisil, M.5    Young, H.A.6
  • 56
    • 0030712367 scopus 로고    scopus 로고
    • Regulation of experimental autoimmune encephalomyelitis by natural killer (NK) cells
    • Zhang B.-n., Yamamura T., Kondo T., Fujiwara M., and Tabira T. Regulation of experimental autoimmune encephalomyelitis by natural killer (NK) cells. J Exp Med 186 10 (1997) 1677-1687
    • (1997) J Exp Med , vol.186 , Issue.10 , pp. 1677-1687
    • Zhang, B.-n.1    Yamamura, T.2    Kondo, T.3    Fujiwara, M.4    Tabira, T.5
  • 57
    • 44449127680 scopus 로고    scopus 로고
    • In vivo regulation of experimental autoimmune encephalomyelitis by NK cells: alteration of primary adaptive responses
    • Winkler-Pickett R., Young H.A., Cherry J.M., Diehl J., Wine J., Back T., et al. In vivo regulation of experimental autoimmune encephalomyelitis by NK cells: alteration of primary adaptive responses. J Immunol 180 7 (2008) 4495-4506
    • (2008) J Immunol , vol.180 , Issue.7 , pp. 4495-4506
    • Winkler-Pickett, R.1    Young, H.A.2    Cherry, J.M.3    Diehl, J.4    Wine, J.5    Back, T.6
  • 58
    • 0032700063 scopus 로고    scopus 로고
    • IL-6 plays a crucial role in the induction phase of myelin oligodendrocyte glycoprotein 35-55 induced experimental autoimmune encephalomyelitis
    • Okuda Y., Sakoda S., Fujimura H., Saeki Y., Kishimoto T., and Yanagihara T. IL-6 plays a crucial role in the induction phase of myelin oligodendrocyte glycoprotein 35-55 induced experimental autoimmune encephalomyelitis. J Neuroimmunol 101 2 (1999) 188-196
    • (1999) J Neuroimmunol , vol.101 , Issue.2 , pp. 188-196
    • Okuda, Y.1    Sakoda, S.2    Fujimura, H.3    Saeki, Y.4    Kishimoto, T.5    Yanagihara, T.6
  • 59
    • 0037449737 scopus 로고    scopus 로고
    • Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
    • Aggarwal S., Ghilardi N., Xie M.H., de Sauvage F.J., and Gurney A.L. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J Biol Chem 278 3 (2003) 1910-1914
    • (2003) J Biol Chem , vol.278 , Issue.3 , pp. 1910-1914
    • Aggarwal, S.1    Ghilardi, N.2    Xie, M.H.3    de Sauvage, F.J.4    Gurney, A.L.5
  • 60
    • 36248941490 scopus 로고    scopus 로고
    • IL-10 or not IL-10: that is the question
    • Jankovic D., and Trinchieri G. IL-10 or not IL-10: that is the question. Nat Immunol 8 12 (2007) 1281-1283
    • (2007) Nat Immunol , vol.8 , Issue.12 , pp. 1281-1283
    • Jankovic, D.1    Trinchieri, G.2
  • 61
  • 63
    • 0035905471 scopus 로고    scopus 로고
    • Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis
    • Singh A.K., Wilson M.T., Hong S., Olivares-Villagomez D., Du C., Stanic A.K., et al. Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis. J Exp Med 194 12 (2001) 1801-1811
    • (2001) J Exp Med , vol.194 , Issue.12 , pp. 1801-1811
    • Singh, A.K.1    Wilson, M.T.2    Hong, S.3    Olivares-Villagomez, D.4    Du, C.5    Stanic, A.K.6
  • 64
    • 0041968838 scopus 로고    scopus 로고
    • Activation of invariant NKT cells by alphaGalCer administration protects mice from MOG35-55-induced EAE: critical roles for administration route and IFN-gamma
    • Furlan R., Bergami A., Cantarella D., Brambilla E., Taniguchi M., et al. Activation of invariant NKT cells by alphaGalCer administration protects mice from MOG35-55-induced EAE: critical roles for administration route and IFN-gamma. Eur J Immunol 33 7 (2003) 1830-1838
    • (2003) Eur J Immunol , vol.33 , Issue.7 , pp. 1830-1838
    • Furlan, R.1    Bergami, A.2    Cantarella, D.3    Brambilla, E.4    Taniguchi, M.5
  • 66
    • 0141719702 scopus 로고    scopus 로고
    • Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
    • Howitz K.T., Bitterman K.J., Cohen H.Y., Lamming D.W., Lavu S., Wood J.G., et al. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 425 6954 (2003) 191-196
    • (2003) Nature , vol.425 , Issue.6954 , pp. 191-196
    • Howitz, K.T.1    Bitterman, K.J.2    Cohen, H.Y.3    Lamming, D.W.4    Lavu, S.5    Wood, J.G.6
  • 67
    • 4043165678 scopus 로고    scopus 로고
    • Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
    • Araki T., Sasaki Y., and Milbrandt J. Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science 305 5686 (2004) 1010-1013
    • (2004) Science , vol.305 , Issue.5686 , pp. 1010-1013
    • Araki, T.1    Sasaki, Y.2    Milbrandt, J.3
  • 68
    • 0034677535 scopus 로고    scopus 로고
    • Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
    • Imai S., Armstrong C.M., Kaeberlein M., and Guarente L. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 403 6771 (2000) 795-800
    • (2000) Nature , vol.403 , Issue.6771 , pp. 795-800
    • Imai, S.1    Armstrong, C.M.2    Kaeberlein, M.3    Guarente, L.4
  • 69
    • 3142740860 scopus 로고    scopus 로고
    • Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
    • Cohen H.Y., Miller C., Bitterman K.J., Wall N.R., Hekking B., Kessler B., et al. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 305 5682 (2004) 390-392
    • (2004) Science , vol.305 , Issue.5682 , pp. 390-392
    • Cohen, H.Y.1    Miller, C.2    Bitterman, K.J.3    Wall, N.R.4    Hekking, B.5    Kessler, B.6
  • 71
    • 3242719545 scopus 로고    scopus 로고
    • Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
    • Yeung F., Hoberg J.E., Ramsey C.S., Keller M.D., Jones D.R., Frye R.A., et al. Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. Embo J 23 12 (2004) 2369-2380
    • (2004) Embo J , vol.23 , Issue.12 , pp. 2369-2380
    • Yeung, F.1    Hoberg, J.E.2    Ramsey, C.S.3    Keller, M.D.4    Jones, D.R.5    Frye, R.A.6
  • 72
    • 20144365700 scopus 로고    scopus 로고
    • Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes
    • Frescas D., Valenti L., and Accili D. Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes. J Biol Chem 280 21 (2005) 20589-20595
    • (2005) J Biol Chem , vol.280 , Issue.21 , pp. 20589-20595
    • Frescas, D.1    Valenti, L.2    Accili, D.3
  • 73
    • 33746931148 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma as a molecular target of resveratrol-induced modulation of polyamine metabolism
    • Ulrich S., Loitsch S.M., Rau O., von Knethen A., Brune B., Schubert-Zsilavecz M., et al. Peroxisome proliferator-activated receptor gamma as a molecular target of resveratrol-induced modulation of polyamine metabolism. Cancer Res 66 14 (2006) 7348-7354
    • (2006) Cancer Res , vol.66 , Issue.14 , pp. 7348-7354
    • Ulrich, S.1    Loitsch, S.M.2    Rau, O.3    von Knethen, A.4    Brune, B.5    Schubert-Zsilavecz, M.6
  • 74
    • 33749349202 scopus 로고    scopus 로고
    • Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice
    • Zang M., Xu S., Maitland-Toolan K.A., Zuccollo A., Hou X., Jiang B., et al. Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice. Diabetes 55 8 (2006) 2180-2191
    • (2006) Diabetes , vol.55 , Issue.8 , pp. 2180-2191
    • Zang, M.1    Xu, S.2    Maitland-Toolan, K.A.3    Zuccollo, A.4    Hou, X.5    Jiang, B.6
  • 75
    • 34249846128 scopus 로고    scopus 로고
    • Resveratrol stimulates AMP kinase activity in neurons
    • Dasgupta B., and Milbrandt J. Resveratrol stimulates AMP kinase activity in neurons. Proc Natl Acad Sci U S A 104 17 (2007) 7217-7222
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.17 , pp. 7217-7222
    • Dasgupta, B.1    Milbrandt, J.2
  • 76
    • 34547545892 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha
    • Jager S., Handschin C., St-Pierre J., and Spiegelman B.M. AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc Natl Acad Sci U S A 104 29 (2007) 12017-12022
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.29 , pp. 12017-12022
    • Jager, S.1    Handschin, C.2    St-Pierre, J.3    Spiegelman, B.M.4
  • 77
    • 4644302857 scopus 로고    scopus 로고
    • Resveratrol analogues as selective cyclooxygenase-2 inhibitors: synthesis and structure-activity relationship
    • Murias M., Handler N., Erker T., Pleban K., Ecker G., Saiko P., et al. Resveratrol analogues as selective cyclooxygenase-2 inhibitors: synthesis and structure-activity relationship. Bioorg Med Chem 12 21 (2004) 5571-5578
    • (2004) Bioorg Med Chem , vol.12 , Issue.21 , pp. 5571-5578
    • Murias, M.1    Handler, N.2    Erker, T.3    Pleban, K.4    Ecker, G.5    Saiko, P.6
  • 78
    • 2642559707 scopus 로고    scopus 로고
    • Effects of cis-resveratrol on inflammatory murine macrophages: antioxidant activity and down-regulation of inflammatory genes
    • Leiro J., Alvarez E., Arranz J.A., Laguna R., Uriarte E., and Orallo F. Effects of cis-resveratrol on inflammatory murine macrophages: antioxidant activity and down-regulation of inflammatory genes. J Leukoc Biol 75 6 (2004) 1156-1165
    • (2004) J Leukoc Biol , vol.75 , Issue.6 , pp. 1156-1165
    • Leiro, J.1    Alvarez, E.2    Arranz, J.A.3    Laguna, R.4    Uriarte, E.5    Orallo, F.6
  • 79
    • 0031444281 scopus 로고    scopus 로고
    • Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor
    • Gehm B.D., McAndrews J.M., Chien P.-Y., and Jameson J.L. Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor. PNAS 94 25 (1997) 14138-14143
    • (1997) PNAS , vol.94 , Issue.25 , pp. 14138-14143
    • Gehm, B.D.1    McAndrews, J.M.2    Chien, P.-Y.3    Jameson, J.L.4


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