메뉴 건너뛰기




Volumn 8, Issue 6, 2002, Pages 586-595

Matrix metalloproteinases and neuroinflammation in multiple sclerosis

Author keywords

Blood brain barrier; Demyelination; Matrix metalloproteinase; Multiple sclerosis; Neuroinflammation; Stromelysin

Indexed keywords

MATRIX METALLOPROTEINASE; MYELIN; PROTEINASE;

EID: 0036892580     PISSN: 10738584     EISSN: None     Source Type: Journal    
DOI: 10.1177/1073858402238517     Document Type: Review
Times cited : (118)

References (87)
  • 2
    • 0035478029 scopus 로고    scopus 로고
    • Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia
    • Asahi M, Wang X, Mori T, Sumii T, Jung JC, Moskowitz MA, and others. 2001. Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia. J Neurosci 21:7724-32.
    • (2001) J Neurosci , vol.21 , pp. 7724-7732
    • Asahi, M.1    Wang, X.2    Mori, T.3    Sumii, T.4    Jung, J.C.5    Moskowitz, M.A.6
  • 3
    • 0030970058 scopus 로고    scopus 로고
    • Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis
    • Benveniste EN. 1997. Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis [Review]. J Mol Med 75:165-73.
    • (1997) J Mol Med , vol.75 , pp. 165-173
    • Benveniste, E.N.1
  • 4
    • 0018879480 scopus 로고
    • Proteinase inhibitors suppress the development of experimental allergic encephalomyelitis
    • Brosnan CF, Cammer W, Norton WT, Bloom BR. 1980. Proteinase inhibitors suppress the development of experimental allergic encephalomyelitis. Nature 285:235-7.
    • (1980) Nature , vol.285 , pp. 235-237
    • Brosnan, C.F.1    Cammer, W.2    Norton, W.T.3    Bloom, B.R.4
  • 5
    • 0002699681 scopus 로고    scopus 로고
    • Synthetic inhibitors of matrix metalloproteinases
    • Parks WC, Mecham RP, editors. San Diego: Academic Press
    • Brown PD. 1998. Synthetic inhibitors of matrix metalloproteinases. In: Parks WC, Mecham RP, editors. Matrix Metalloproteinases. San Diego: Academic Press. p 243-62.
    • (1998) Matrix Metalloproteinases , pp. 243-262
    • Brown, P.D.1
  • 6
    • 0018148235 scopus 로고
    • Degradation of basic protein in myelin by neutral proteases secreted by stimulated macrophages: A possible mechanism of inflammatory demyelination
    • Cammer W, Bloom BR, Norton WT, Gordon S. 1978. Degradation of basic protein in myelin by neutral proteases secreted by stimulated macrophages: A possible mechanism of inflammatory demyelination. Proc Natl Acad Sci U S A 75:1554-8.
    • (1978) Proc Natl Acad Sci U S A , vol.75 , pp. 1554-1558
    • Cammer, W.1    Bloom, B.R.2    Norton, W.T.3    Gordon, S.4
  • 7
    • 0028901768 scopus 로고
    • Binswanger's disease-revisited
    • Caplan LR. 1995. Binswanger's disease-revisited [Review]. Neurology 45:626-33.
    • (1995) Neurology , vol.45 , pp. 626-633
    • Caplan, L.R.1
  • 9
    • 10744226623 scopus 로고    scopus 로고
    • Matrix metalloproteinase expression during experimental autoimmune encephalomyelitis and effects of a combined matrix metalloproteinase and tumour necrosis factor-alpha inhibitor
    • Clements JM, Cossins JA, Wells GM, Corkill DJ, Helfrich K, Wood LM, and others. 1997. Matrix metalloproteinase expression during experimental autoimmune encephalomyelitis and effects of a combined matrix metalloproteinase and tumour necrosis factor-alpha inhibitor. J Neuroimmunol 74:85-94.
    • (1997) J Neuroimmunol , vol.74 , pp. 85-94
    • Clements, J.M.1    Cossins, J.A.2    Wells, G.M.3    Corkill, D.J.4    Helfrich, K.5    Wood, L.M.6
  • 10
    • 0027243871 scopus 로고
    • Protease production by cultured microglia: Substrate gel analysis and immobilized matrix degradation
    • Colton CA, Keri JE, Chen WT, Monsky WL. 1993. Protease production by cultured microglia: Substrate gel analysis and immobilized matrix degradation. J Neurosci Res 35:297-304.
    • (1993) J Neurosci Res , vol.35 , pp. 297-304
    • Colton, C.A.1    Keri, J.E.2    Chen, W.T.3    Monsky, W.L.4
  • 11
    • 0032881663 scopus 로고    scopus 로고
    • Cerebrospinal fluid levels of MMP-2, 7, and 9 are elevated in association with human immunodeficiency virus dementia
    • Conant K, McArthur JC, Griffin DE, Sjulson L, Wahl LM, Irani DN. 1999. Cerebrospinal fluid levels of MMP-2, 7, and 9 are elevated in association with human immunodeficiency virus dementia. Ann Neurol 46:391-8.
    • (1999) Ann Neurol , vol.46 , pp. 391-398
    • Conant, K.1    McArthur, J.C.2    Griffin, D.E.3    Sjulson, L.4    Wahl, L.M.5    Irani, D.N.6
  • 12
    • 0033081796 scopus 로고    scopus 로고
    • Plasminogen activators and matrix metalloproteases, mediators of extracellular proteolysis in inflammatory demyelination of the central nervous system
    • Cuzner ML, Opdenakker G. 1999. Plasminogen activators and matrix metalloproteases, mediators of extracellular proteolysis in inflammatory demyelination of the central nervous system [Review]. J Neuroimmunol 94:1-14.
    • (1999) J Neuroimmunol , vol.94 , pp. 1-14
    • Cuzner, M.L.1    Opdenakker, G.2
  • 13
    • 84974201150 scopus 로고
    • The histology of disseminated sclerosis
    • Dawson JW. 1916. The histology of disseminated sclerosis. Trans R Soc Edin 50:517-25.
    • (1916) Trans R Soc Edin , vol.50 , pp. 517-525
    • Dawson, J.W.1
  • 14
    • 0033405694 scopus 로고    scopus 로고
    • Resistance of young gelatinase B-deficient mice to experimental autoimmune encephalomyelitis and necrotizing tail lesions
    • Dubois B, Masure S, Hurtenbach U, Paemen L, Heremans H, van den OJ, and others. 1999. Resistance of young gelatinase B-deficient mice to experimental autoimmune encephalomyelitis and necrotizing tail lesions. J Clin Invest 104:1507-15.
    • (1999) J Clin Invest , vol.104 , pp. 1507-1515
    • Dubois, B.1    Masure, S.2    Hurtenbach, U.3    Paemen, L.4    Heremans, H.5    Van den, O.J.6
  • 15
    • 0031002545 scopus 로고    scopus 로고
    • Axonal damage in acute multiple sclerosis lesions
    • Ferguson B, Matyszak MK, Esiri MM, Perry VH. 1997. Axonal damage in acute multiple sclerosis lesions. Brain 120:393-9.
    • (1997) Brain , vol.120 , pp. 393-399
    • Ferguson, B.1    Matyszak, M.K.2    Esiri, M.M.3    Perry, V.H.4
  • 16
    • 0034790897 scopus 로고    scopus 로고
    • Matrix metalloproteinases and their tissue inhibitors as markers of disease subtype and response to interferon-beta therapy in relapsing and secondary-progressive multiple sclerosis patients
    • Galboiz Y, Shapiro S, Lahat N, Rawashdeh H, Miller A. 2001. Matrix metalloproteinases and their tissue inhibitors as markers of disease subtype and response to interferon-beta therapy in relapsing and secondary-progressive multiple sclerosis patients. Ann Neurol 50:443-51.
    • (2001) Ann Neurol , vol.50 , pp. 443-451
    • Galboiz, Y.1    Shapiro, S.2    Lahat, N.3    Rawashdeh, H.4    Miller, A.5
  • 17
    • 0026013693 scopus 로고
    • Blood-brain barrier damage in acute multiple sclerosis plaques. An immunocytological study
    • Gay D, Esiri M. 1991. Blood-brain barrier damage in acute multiple sclerosis plaques. An immunocytological study. Brain 114:557-72.
    • (1991) Brain , vol.114 , pp. 557-572
    • Gay, D.1    Esiri, M.2
  • 18
    • 0032950794 scopus 로고    scopus 로고
    • Identification of autoantibodies associated with myelin damage in multiple sclerosis
    • Genain CP, Cannella B, Hauser SL, Raine CS. 1999. Identification of autoantibodies associated with myelin damage in multiple sclerosis. Nat Med 5:170-5.
    • (1999) Nat Med , vol.5 , pp. 170-175
    • Genain, C.P.1    Cannella, B.2    Hauser, S.L.3    Raine, C.S.4
  • 19
    • 0027944171 scopus 로고
    • Reversal of experimental autoimmune encephalomyelitis with a hydroxamate inhibitor of matrix metalloproteases
    • Gijbels K, Galardy RE, Steinman L. 1994. Reversal of experimental autoimmune encephalomyelitis with a hydroxamate inhibitor of matrix metalloproteases. J Clin Invest 94:2177-82.
    • (1994) J Clin Invest , vol.94 , pp. 2177-2182
    • Gijbels, K.1    Galardy, R.E.2    Steinman, L.3
  • 20
    • 0026442957 scopus 로고
    • Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders
    • Gijbels K, Masure S, Carton H, Opdenakker G. 1992. Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders. J Neuroimmunol 41:29-34.
    • (1992) J Neuroimmunol , vol.41 , pp. 29-34
    • Gijbels, K.1    Masure, S.2    Carton, H.3    Opdenakker, G.4
  • 21
    • 0027368518 scopus 로고
    • Gelatinase B is present in the cerebrospinal fluid during experimental autoimmune encephalomyelitis and cleaves myelin basic protein
    • Gijbels K, Proost P, Masure S, Carton H, Billiau A, Opdenakker G. 1993. Gelatinase B is present in the cerebrospinal fluid during experimental autoimmune encephalomyelitis and cleaves myelin basic protein. J Neurosci Res 36:432-40.
    • (1993) J Neurosci Res , vol.36 , pp. 432-440
    • Gijbels, K.1    Proost, P.2    Masure, S.3    Carton, H.4    Billiau, A.5    Opdenakker, G.6
  • 22
    • 17944383774 scopus 로고    scopus 로고
    • Matrix metalloproteinase 9 (gelatinase B) in cerebrospinal fluid of HTLV-1 infected patients with tropical spastic paraparesis
    • Giraudon P, Vernant JC, Confavreux C, Belin MF, Desgranges C. 1998. Matrix metalloproteinase 9 (gelatinase B) in cerebrospinal fluid of HTLV-1 infected patients with tropical spastic paraparesis. Neurology 50(6):1920.
    • (1998) Neurology , vol.50 , Issue.6 , pp. 1920
    • Giraudon, P.1    Vernant, J.C.2    Confavreux, C.3    Belin, M.F.4    Desgranges, C.5
  • 23
    • 0028934085 scopus 로고
    • Cytokines regulate gelatinase A and B (matrix metalloproteinase 2 and 9) activity in cultured rat astrocytes
    • Gottschall PE, Yu X. 1995. Cytokines regulate gelatinase A and B (matrix metalloproteinase 2 and 9) activity in cultured rat astrocytes. J Neurochem 64:1513-20.
    • (1995) J Neurochem , vol.64 , pp. 1513-1520
    • Gottschall, P.E.1    Yu, X.2
  • 25
    • 0028792449 scopus 로고
    • Microvascular basal lamina antigens disappear during cerebral ischemia and reperfusion
    • Hamann GF, Okada Y, Fitridge R, del Zoppo GJ. 1995. Microvascular basal lamina antigens disappear during cerebral ischemia and reperfusion. Stroke 26:2120-6.
    • (1995) Stroke , vol.26 , pp. 2120-2126
    • Hamann, G.F.1    Okada, Y.2    Fitridge, R.3    Del Zoppo, G.J.4
  • 26
    • 0025107677 scopus 로고
    • Cytokine accumulations in CSF of multiple sclerosis patients: Frequent detection of interleukin-1 and tumor necrosis factor but not interleukin-6
    • Hauser SL, Doolittle TH, Lincoln R, Brown RH, Dinarello CA. 1990. Cytokine accumulations in CSF of multiple sclerosis patients: Frequent detection of interleukin-1 and tumor necrosis factor but not interleukin-6. Neurology 40:1735-9.
    • (1990) Neurology , vol.40 , pp. 1735-1739
    • Hauser, S.L.1    Doolittle, T.H.2    Lincoln, R.3    Brown, R.H.4    Dinarello, C.A.5
  • 28
    • 0029046464 scopus 로고
    • Suppression of experimental allergic encephalomyelitis in the Lewis rat by the matrix metalloproteinase inhibitor Ro31-9790
    • Hewson AK, Smith T, Leonard JP, Cuzner ML. 1995. Suppression of experimental allergic encephalomyelitis in the Lewis rat by the matrix metalloproteinase inhibitor Ro31-9790. Inflam Res 44:345-9.
    • (1995) Inflam Res , vol.44 , pp. 345-349
    • Hewson, A.K.1    Smith, T.2    Leonard, J.P.3    Cuzner, M.L.4
  • 30
    • 0034963261 scopus 로고    scopus 로고
    • Chronic cerebral hypoperfusion induces MMP-2 but not MMP-9 expression in the microglia and vascular endothelium of white matter
    • Ihara M, Tomimoto H, Kinoshita M, Oh J, Noda M, Wakita H, and others. 2001. Chronic cerebral hypoperfusion induces MMP-2 but not MMP-9 expression in the microglia and vascular endothelium of white matter. J Cereb Blood Flow Metab 21:828-34.
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 828-834
    • Ihara, M.1    Tomimoto, H.2    Kinoshita, M.3    Oh, J.4    Noda, M.5    Wakita, H.6
  • 31
    • 0025015647 scopus 로고
    • Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone
    • Jonat C, Rahmsdorf HJ, Park KK, Cato AC, Gebel S, Ponta H, and others. 1990. Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone. Cell 62:1189-204.
    • (1990) Cell , vol.62 , pp. 1189-1204
    • Jonat, C.1    Rahmsdorf, H.J.2    Park, K.K.3    Cato, A.C.4    Gebel, S.5    Ponta, H.6
  • 32
    • 0024990661 scopus 로고
    • Breakdown of the blood-brain barrier precedes symptoms and other MRI signs of new lesions in multiple sclerosis. Pathogenetic and clinical implications
    • Kermode AG, Thompson AJ, Tofts P, MacManus DG, Kendall BE, Kingsley DP, and others. 1990. Breakdown of the blood-brain barrier precedes symptoms and other MRI signs of new lesions in multiple sclerosis. Pathogenetic and clinical implications. Brain 113:1477-89.
    • (1990) Brain , vol.113 , pp. 1477-1489
    • Kermode, A.G.1    Thompson, A.J.2    Tofts, P.3    MacManus, D.G.4    Kendall, B.E.5    Kingsley, D.P.6
  • 33
    • 0031963338 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 and -7 are regulated in experimental autoimmune encephalomyelitis
    • Kieseier BC, Kiefer R, Clements JM, Miller K, Wells GM, Schweitzer T, and others. 1998. Matrix metalloproteinase-9 and -7 are regulated in experimental autoimmune encephalomyelitis. Brain 121:159-66.
    • (1998) Brain , vol.121 , pp. 159-166
    • Kieseier, B.C.1    Kiefer, R.2    Clements, J.M.3    Miller, K.4    Wells, G.M.5    Schweitzer, T.6
  • 34
    • 0033551546 scopus 로고    scopus 로고
    • Matrix metalloproteinases in inflammatory demyelination: Targets for treatment
    • Kieseier BC, Seifert T, Giovannoni G, Hartung HP. 1999. Matrix metalloproteinases in inflammatory demyelination: Targets for treatment [Review]. Neurology 53:20-5.
    • (1999) Neurology , vol.53 , pp. 20-25
    • Kieseier, B.C.1    Seifert, T.2    Giovannoni, G.3    Hartung, H.P.4
  • 35
    • 0028345645 scopus 로고
    • Quantitative zymography: Detection of picogram quantities of gelatinases
    • Kleiner DE, Stetler-Stevenson WG. 1994. Quantitative zymography: Detection of picogram quantities of gelatinases. Anal Biochem 218:325-9.
    • (1994) Anal Biochem , vol.218 , pp. 325-329
    • Kleiner, D.E.1    Stetler-Stevenson, W.G.2
  • 36
    • 0032948343 scopus 로고    scopus 로고
    • Serum gelatinase B, TIMP-1 and TIMP-2 levels in multiple sclerosis. A longitudinal clinical and MRI study
    • Lee MA, Palace J, Stabler G, Ford J, Gearing A, Miller K. 1999. Serum gelatinase B, TIMP-1 and TIMP-2 levels in multiple sclerosis. A longitudinal clinical and MRI study. Brain 122:191-7.
    • (1999) Brain , vol.122 , pp. 191-197
    • Lee, M.A.1    Palace, J.2    Stabler, G.3    Ford, J.4    Gearing, A.5    Miller, K.6
  • 37
    • 0034845846 scopus 로고    scopus 로고
    • Inhibition of matrix metalloproteinases and tumour necrosis factor alpha converting enzyme as adjuvant therapy in pneumococcal meningitis
    • Leib SL, Clements JM, Lindberg RL, Heimgartner C, Loeffler JM, Pfister LA, and others. 2001. Inhibition of matrix metalloproteinases and tumour necrosis factor alpha converting enzyme as adjuvant therapy in pneumococcal meningitis. Brain 124:1734-42.
    • (2001) Brain , vol.124 , pp. 1734-1742
    • Leib, S.L.1    Clements, J.M.2    Lindberg, R.L.3    Heimgartner, C.4    Loeffler, J.M.5    Pfister, L.A.6
  • 38
    • 0015333994 scopus 로고
    • Cerebral vascular permeability and cellular infiltration in experimental allergic encephalomyelitis
    • Leibowitz S, Kennedy L. 1972. Cerebral vascular permeability and cellular infiltration in experimental allergic encephalomyelitis. Immunology 22:859-69.
    • (1972) Immunology , vol.22 , pp. 859-869
    • Leibowitz, S.1    Kennedy, L.2
  • 39
    • 0031798063 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 (gelatinase B) is selectively elevated in CSF during relapses and stable phases of multiple sclerosis
    • Leppert D, Ford J, Stabler G, Grygar C, Lienert C, Huber S, and others. 1998. Matrix metalloproteinase-9 (gelatinase B) is selectively elevated in CSF during relapses and stable phases of multiple sclerosis. Brain 121:2327-34.
    • (1998) Brain , vol.121 , pp. 2327-2334
    • Leppert, D.1    Ford, J.2    Stabler, G.3    Grygar, C.4    Lienert, C.5    Huber, S.6
  • 40
    • 0034455606 scopus 로고    scopus 로고
    • Matrix metalloproteinase (MMP)-8 and MMP-9 in cerebrospinal fluid during bacterial meningitis: Association with blood-brain barrier damage and neurological sequelae
    • Leppert D, Leib SL, Grygar C, Miller KM, Schaad UB, Hollander GA. 2000. Matrix metalloproteinase (MMP)-8 and MMP-9 in cerebrospinal fluid during bacterial meningitis: Association with blood-brain barrier damage and neurological sequelae. Clin Infect Dis 31:80-4.
    • (2000) Clin Infect Dis , vol.31 , pp. 80-84
    • Leppert, D.1    Leib, S.L.2    Grygar, C.3    Miller, K.M.4    Schaad, U.B.5    Hollander, G.A.6
  • 41
    • 0029041446 scopus 로고
    • T cell gelatinases mediate basement membrane transmigration in vitro
    • Leppert D, Waubant E, Galardy R, Bunnett NW, Hauser SL. 1995. T cell gelatinases mediate basement membrane transmigration in vitro. J Immunol 154:4379-89.
    • (1995) J Immunol , vol.154 , pp. 4379-4389
    • Leppert, D.1    Waubant, E.2    Galardy, R.3    Bunnett, N.W.4    Hauser, S.L.5
  • 43
    • 0034842248 scopus 로고    scopus 로고
    • The expression profile of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in lesions and normal appearing white matter of multiple sclerosis
    • Lindberg RL, De Groot CJ, Montagne L, Freitag P, van der Valk P, Kappos L, and others. 2001. The expression profile of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in lesions and normal appearing white matter of multiple sclerosis. Brain 124:1743-53.
    • (2001) Brain , vol.124 , pp. 1743-1753
    • Lindberg, R.L.1    De Groot, C.J.2    Montagne, L.3    Freitag, P.4    Van der Valk, P.5    Kappos, L.6
  • 44
    • 0019195010 scopus 로고
    • Metastatic potential correlates with enzymatic degradation of basement membrane collagen
    • Liotta LA, Tryggvason K, Garbisa S, Hart I, Foltz CM, Shafie S. 1980. Metastatic potential correlates with enzymatic degradation of basement membrane collagen. Nature 284:67-8.
    • (1980) Nature , vol.284 , pp. 67-68
    • Liotta, L.A.1    Tryggvason, K.2    Garbisa, S.3    Hart, I.4    Foltz, C.M.5    Shafie, S.6
  • 45
    • 0034124052 scopus 로고    scopus 로고
    • Increased activity of matrix metalloproteinases in the cerebrospinal fluid of patients with HIV-associated neurological diseases
    • Liuzzi GM, Mastroianni CM, Santacroce MP, Fanelli M, D'Agostino C, Vullo V, and others. 2000. Increased activity of matrix metalloproteinases in the cerebrospinal fluid of patients with HIV-associated neurological diseases. J Neurovirol 6:156-63.
    • (2000) J Neurovirol , vol.6 , pp. 156-163
    • Liuzzi, G.M.1    Mastroianni, C.M.2    Santacroce, M.P.3    Fanelli, M.4    D'Agostino, C.5    Vullo, V.6
  • 46
    • 0032821995 scopus 로고    scopus 로고
    • Extracellular matrix degradation by metalloproteinases and central nervous system diseases
    • Lukes A, Mun-Bryce S, Lukes M, Rosenberg GA. 1999. Extracellular matrix degradation by metalloproteinases and central nervous system diseases [Review]. Mol Neurobiol 19:267-84.
    • (1999) Mol Neurobiol , vol.19 , pp. 267-284
    • Lukes, A.1    Mun-Bryce, S.2    Lukes, M.3    Rosenberg, G.A.4
  • 47
    • 0029867128 scopus 로고    scopus 로고
    • Matrix metalloproteinases in the normal human central nervous system, microglial nodules, and multiple sclerosis lesions
    • Maeda A, Sobel RA. 1996. Matrix metalloproteinases in the normal human central nervous system, microglial nodules, and multiple sclerosis lesions. J Neuropathol Exp Neurol 55:300-9.
    • (1996) J Neuropathol Exp Neurol , vol.55 , pp. 300-309
    • Maeda, A.1    Sobel, R.A.2
  • 48
    • 0030248444 scopus 로고    scopus 로고
    • Delayed-type hypersensitivity lesions in the central nervous system are prevented by inhibitors of matrix metalloproteinases
    • Matyszak MK, Perry VH. 1996. Delayed-type hypersensitivity lesions in the central nervous system are prevented by inhibitors of matrix metalloproteinases. J Neuroimmunol 69:141-9.
    • (1996) J Neuroimmunol , vol.69 , pp. 141-149
    • Matyszak, M.K.1    Perry, V.H.2
  • 49
    • 0030977009 scopus 로고    scopus 로고
    • Control of type IV collagenase activity by components of the urokinase-plasmin system: A regulatory mechanism with cell-bound reactants
    • Mazzieri R, Masiero L, Zanetta L, Monea S, Onisto M, Garbisa S, and others. 1997. Control of type IV collagenase activity by components of the urokinase-plasmin system: A regulatory mechanism with cell-bound reactants. EMBO J 16:2319-32.
    • (1997) EMBO J , vol.16 , pp. 2319-2332
    • Mazzieri, R.1    Masiero, L.2    Zanetta, L.3    Monea, S.4    Onisto, M.5    Garbisa, S.6
  • 50
    • 0033981540 scopus 로고    scopus 로고
    • Overexpression of copper and zinc superoxide dismutase in transgenic mice prevents the induction and activation of matrix metalloproteinases after cold injury-induced brain trauma
    • Morita-Fujimura Y, Fujimura M, Gasche Y, Copin JC, Chan PH. 2000. Overexpression of copper and zinc superoxide dismutase in transgenic mice prevents the induction and activation of matrix metalloproteinases after cold injury-induced brain trauma. J Cereb Blood Flow Metab 20:130-8.
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 130-138
    • Morita-Fujimura, Y.1    Fujimura, M.2    Gasche, Y.3    Copin, J.C.4    Chan, P.H.5
  • 51
    • 0031831764 scopus 로고    scopus 로고
    • Gelatinase B modulates selective opening of the blood-brain barrier during inflammation
    • Mun-Bryce S, Rosenberg GA. 1998a. Gelatinase B modulates selective opening of the blood-brain barrier during inflammation. Am J Physiol 274:R1203-11.
    • (1998) Am J Physiol , vol.274
    • Mun-Bryce, S.1    Rosenberg, G.A.2
  • 52
    • 0031768024 scopus 로고    scopus 로고
    • Matrix metalloproteinases in cerebrovascular disease
    • Mun-Bryce S, Rosenberg GA. 1998b. Matrix metalloproteinases in cerebrovascular disease [Review]. J Cereb Blood Flow Metab 18:1163-72.
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 1163-1172
    • Mun-Bryce, S.1    Rosenberg, G.A.2
  • 53
    • 0030957218 scopus 로고    scopus 로고
    • Activation mechanisms of matrix metalloproteinases
    • Nagase H. 1997. Activation mechanisms of matrix metalloproteinases [Review]. Biol Chem 378:151-60.
    • (1997) Biol Chem , vol.378 , pp. 151-160
    • Nagase, H.1
  • 54
    • 0033618337 scopus 로고    scopus 로고
    • Matrix metalloproteinases
    • Nagase H, Woessner JF Jr. 1999. Matrix metalloproteinases [Review]. J Biol Chem 274:21491-4.
    • (1999) J Biol Chem , vol.274 , pp. 21491-21494
    • Nagase, H.1    Woessner J.F., Jr.2
  • 55
    • 0033999308 scopus 로고    scopus 로고
    • Matrix metalloproteinases: Biologic activity and clinical implications
    • Nelson AR, Fingleton B, Rothenberg ML, Matrisian LM. 2000. Matrix metalloproteinases: Biologic activity and clinical implications [Review]. J Clin Oncol 18:1135-49.
    • (2000) J Clin Oncol , vol.18 , pp. 1135-1149
    • Nelson, A.R.1    Fingleton, B.2    Rothenberg, M.L.3    Matrisian, L.M.4
  • 56
    • 0035170589 scopus 로고    scopus 로고
    • T-cell- and macrophage-mediated axon damage in the absence of a CNS-specific immune response: Involvement of metalloproteinases
    • Newman TA, Woolley ST, Hughes PM, Sibson NR, Anthony DC, Perry VH. 2001. T-cell- and macrophage-mediated axon damage in the absence of a CNS-specific immune response: Involvement of metalloproteinases. Brain 124:2203-14.
    • (2001) Brain , vol.124 , pp. 2203-2214
    • Newman, T.A.1    Woolley, S.T.2    Hughes, P.M.3    Sibson, N.R.4    Anthony, D.C.5    Perry, V.H.6
  • 58
    • 0023024460 scopus 로고
    • A metalloproteinase from human rheumatoid synovial fibroblasts that digests connective tissue matrix components. Purification and characterization
    • Okada Y, Nagase H, Harris ED. 1986. A metalloproteinase from human rheumatoid synovial fibroblasts that digests connective tissue matrix components. Purification and characterization. J Biol Chem 261:14245-55.
    • (1986) J Biol Chem , vol.261 , pp. 14245-14255
    • Okada, Y.1    Nagase, H.2    Harris, E.D.3
  • 59
    • 0017106754 scopus 로고
    • Experimental allergic encephalomyelitis: Role of fibrin deposition in immunopathogenesis of inflammation in rats
    • Paterson PY. 1976. Experimental allergic encephalomyelitis: Role of fibrin deposition in immunopathogenesis of inflammation in rats. Fed Proc 35:2428-34.
    • (1976) Fed Proc , vol.35 , pp. 2428-2434
    • Paterson, P.Y.1
  • 61
    • 0035283335 scopus 로고    scopus 로고
    • Reduction in glial immunity and neuropathology by a PAF antagonist and an MMP and TNFalpha inhibitor in SCID mice with HIV-1 encephalitis
    • Persidsky Y, Limoges J, Rasmussen J, Zheng J, Gearing A, Gendelman HE. 2001. Reduction in glial immunity and neuropathology by a PAF antagonist and an MMP and TNFalpha inhibitor in SCID mice with HIV-1 encephalitis. J Neuroimmunol 114:57-68.
    • (2001) J Neuroimmunol , vol.114 , pp. 57-68
    • Persidsky, Y.1    Limoges, J.2    Rasmussen, J.3    Zheng, J.4    Gearing, A.5    Gendelman, H.E.6
  • 62
    • 0011743262 scopus 로고
    • Vascular architecture of the lesions of multiple sclerosis
    • Putnam TJ, Adler A. 1937. Vascular architecture of the lesions of multiple sclerosis. Arch Neurol Psychiatry 38:1-15.
    • (1937) Arch Neurol Psychiatry , vol.38 , pp. 1-15
    • Putnam, T.J.1    Adler, A.2
  • 63
    • 0033532205 scopus 로고    scopus 로고
    • Activation of matrix metalloproteinase-9 (MMP-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasion
    • Ramos-DeSimone N, Hahn-Dantona E, Sipley J, Nagase H, French DL, Quigley JP, and others. 1999. Activation of matrix metalloproteinase-9 (MMP-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasion. J Biol Chem 274:13066-76.
    • (1999) J Biol Chem , vol.274 , pp. 13066-13076
    • Ramos-DeSimone, N.1    Hahn-Dantona, E.2    Sipley, J.3    Nagase, H.4    French, D.L.5    Quigley, J.P.6
  • 64
    • 0028132773 scopus 로고
    • A comparison of the pathology of primary and secondary progressive multiple sclerosis
    • Revesz T, Kidd D, Thompson AJ, Barnard RO, McDonald WI. 1994. A comparison of the pathology of primary and secondary progressive multiple sclerosis. Brain 117:759-65.
    • (1994) Brain , vol.117 , pp. 759-765
    • Revesz, T.1    Kidd, D.2    Thompson, A.J.3    Barnard, R.O.4    McDonald, W.I.5
  • 65
    • 0015994157 scopus 로고
    • Action of proteolytic and glycolytic enzymes on the permeability of the blood-brain barrier
    • Robert AM, Godeau G. 1974. Action of proteolytic and glycolytic enzymes on the permeability of the blood-brain barrier. Biomedicine 21:36-9.
    • (1974) Biomedicine , vol.21 , pp. 36-39
    • Robert, A.M.1    Godeau, G.2
  • 66
    • 0031959973 scopus 로고    scopus 로고
    • Matrix metalloproteinase expression increases after cerebral focal ischemia in rats: Inhibition of matrix metalloproteinase-9 reduces infarct size
    • Romanic AM, White RF, Arleth AJ, Ohlstein EH, Barone FC. 1998. Matrix metalloproteinase expression increases after cerebral focal ischemia in rats: Inhibition of matrix metalloproteinase-9 reduces infarct size. Stroke 29:1020-30.
    • (1998) Stroke , vol.29 , pp. 1020-1030
    • Romanic, A.M.1    White, R.F.2    Arleth, A.J.3    Ohlstein, E.H.4    Barone, F.C.5
  • 67
    • 0035793934 scopus 로고    scopus 로고
    • Immunohistochemistry of matrix metalloproteinases in reperfusion injury to rat brain: Activation of MMP-9 linked to stromelysin-1 and microglia in cell cultures
    • Rosenberg GA, Cunningham LA, Wallace J, Alexander S, Estrada EY, Grossetete M, and others. 2001. Immunohistochemistry of matrix metalloproteinases in reperfusion injury to rat brain: Activation of MMP-9 linked to stromelysin-1 and microglia in cell cultures. Brain Res 893:104-12.
    • (2001) Brain Res , vol.893 , pp. 104-112
    • Rosenberg, G.A.1    Cunningham, L.A.2    Wallace, J.3    Alexander, S.4    Estrada, E.Y.5    Grossetete, M.6
  • 68
    • 0029889674 scopus 로고    scopus 로고
    • Effect of steroids on CSF matrix metalloproteinases in multiple sclerosis: Relation to blood-brain barrier injury
    • Rosenberg GA, Dencoff JE, Correa N Jr, Reiners M, Ford CC. 1996. Effect of steroids on CSF matrix metalloproteinases in multiple sclerosis: Relation to blood-brain barrier injury. Neurology 46:1626-32.
    • (1996) Neurology , vol.46 , pp. 1626-1632
    • Rosenberg, G.A.1    Dencoff, J.E.2    Correa N., Jr.3    Reiners, M.4    Ford, C.C.5
  • 70
    • 0031693557 scopus 로고    scopus 로고
    • Matrix metalloproteinases and TIMPs are associated with blood-brain barrier opening after reperfusion in rat brain
    • Rosenberg GA, Estrada EY, Dencoff JE. 1998. Matrix metalloproteinases and TIMPs are associated with blood-brain barrier opening after reperfusion in rat brain. Stroke 29:2189-95.
    • (1998) Stroke , vol.29 , pp. 2189-2195
    • Rosenberg, G.A.1    Estrada, E.Y.2    Dencoff, J.E.3
  • 71
    • 0028973084 scopus 로고
    • Tumor necrosis factor-alpha-induced gelatinase B causes delayed opening of the blood-brain barrier: An expanded therapeutic window
    • Rosenberg GA, Estrada EY, Dencoff JE, Stetler-Stevenson WG. 1995. Tumor necrosis factor-alpha-induced gelatinase B causes delayed opening of the blood-brain barrier: An expanded therapeutic window. Brain Res 703:151-5.
    • (1995) Brain Res , vol.703 , pp. 151-155
    • Rosenberg, G.A.1    Estrada, E.Y.2    Dencoff, J.E.3    Stetler-Stevenson, W.G.4
  • 75
    • 0034846419 scopus 로고    scopus 로고
    • White matter damage is assoiciated with matrix metalloproteinases in vascular dementia
    • Rosenberg GA, Sullivan N, Esiri MM. 2001. White matter damage is assoiciated with matrix metalloproteinases in vascular dementia. Stroke 32:1162-8.
    • (2001) Stroke , vol.32 , pp. 1162-1168
    • Rosenberg, G.A.1    Sullivan, N.2    Esiri, M.M.3
  • 76
    • 0017881191 scopus 로고
    • Active multiple sclerosis. Enhanced computerized tomographic imaging of lesions and the effect of corticosteroids
    • Sears ES, Tindall RS, Zarnow H. 1978. Active multiple sclerosis. Enhanced computerized tomographic imaging of lesions and the effect of corticosteroids. Arch Neurol 35:426-34.
    • (1978) Arch Neurol , vol.35 , pp. 426-434
    • Sears, E.S.1    Tindall, R.S.2    Zarnow, H.3
  • 77
    • 0034465872 scopus 로고    scopus 로고
    • Immunological effects of oral high-dose methylprednisolone in acute optic neuritis and multiple sclerosis
    • Sellebjerg F, Christiansen M, Jensen J, Frederiksen JL. 2000. Immunological effects of oral high-dose methylprednisolone in acute optic neuritis and multiple sclerosis. Eur J Neurol 7:281-9.
    • (2000) Eur J Neurol , vol.7 , pp. 281-289
    • Sellebjerg, F.1    Christiansen, M.2    Jensen, J.3    Frederiksen, J.L.4
  • 78
    • 0025852567 scopus 로고
    • Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions
    • Selmaj K, Raine CS, Cannella B, Brosnan CF. 1991. Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions. J Clin Invest 87:949-54.
    • (1991) J Clin Invest , vol.87 , pp. 949-954
    • Selmaj, K.1    Raine, C.S.2    Cannella, B.3    Brosnan, C.F.4
  • 79
    • 0025773147 scopus 로고
    • Association between tumor necrosis factor-alpha and disease progression in patients with multiple sclerosis
    • Sharief MK, Hentges R. 1991. Association between tumor necrosis factor-alpha and disease progression in patients with multiple sclerosis. N Engl J Med 325:467-72.
    • (1991) N Engl J Med , vol.325 , pp. 467-472
    • Sharief, M.K.1    Hentges, R.2
  • 80
    • 0030498666 scopus 로고    scopus 로고
    • Interferon beta-lb decreases the migration of T lymphocytes in vitro: Effects on matrix metalloproteinase-9
    • Stuve O, Dooley NP, Uhm JH, Antel JP, Francis GS, Williams G, and others. 1996. Interferon beta-lb decreases the migration of T lymphocytes in vitro: Effects on matrix metalloproteinase-9. Ann Neurol 40:853-63.
    • (1996) Ann Neurol , vol.40 , pp. 853-863
    • Stuve, O.1    Dooley, N.P.2    Uhm, J.H.3    Antel, J.P.4    Francis, G.S.5    Williams, G.6
  • 81
    • 0032716573 scopus 로고    scopus 로고
    • Changes of serum sICAM-1 and MMP-9 induced by rIFNbeta-lb treatment in relapsing-remitting MS
    • Trojano M, Avolio C, Liuzzi GM, Ruggieri M, Defazio G, Liguori M, and others. 1999. Changes of serum sICAM-1 and MMP-9 induced by rIFNbeta-lb treatment in relapsing-remitting MS [see Comments]. Neurology 53:1402-8.
    • (1999) Neurology , vol.53 , pp. 1402-1408
    • Trojano, M.1    Avolio, C.2    Liuzzi, G.M.3    Ruggieri, M.4    Defazio, G.5    Liguori, M.6
  • 82
    • 0032693982 scopus 로고    scopus 로고
    • Serum MMP-9 and TIMP-1 levels are related to MRI activity in relapsing multiple sclerosis
    • Waubant E, Goodkin DE, Gee L, Bacchetti P, Sloan R, Stewart T, and others. 1999. Serum MMP-9 and TIMP-1 levels are related to MRI activity in relapsing multiple sclerosis. Neurology 53:1397-401.
    • (1999) Neurology , vol.53 , pp. 1397-1401
    • Waubant, E.1    Goodkin, D.E.2    Gee, L.3    Bacchetti, P.4    Sloan, R.5    Stewart, T.6
  • 83
    • 0016428296 scopus 로고
    • Primary demyelination as a non-specific consequence of a cell-mediated immune reaction
    • Wisniewski HM, Bloom BR. 1975. Primary demyelination as a non-specific consequence of a cell-mediated immune reaction. J Exp Med 141:346-59.
    • (1975) J Exp Med , vol.141 , pp. 346-359
    • Wisniewski, H.M.1    Bloom, B.R.2
  • 84
    • 0035882461 scopus 로고    scopus 로고
    • v-Ha-RaS oncogene upregulates the 92-kDa type IV collagenase (MMP-9) gene by increasing cellular superoxide production and activating NF-kappaB
    • Yang JQ, Zhao W, Duan H, Robbins ME, Buettner GR, Oberley LW, and others. 2001. v-Ha-RaS oncogene upregulates the 92-kDa type IV collagenase (MMP-9) gene by increasing cellular superoxide production and activating NF-kappaB. Free Radic Biol Med 31:520-9.
    • (2001) Free Radic Biol Med , vol.31 , pp. 520-529
    • Yang, J.Q.1    Zhao, W.2    Duan, H.3    Robbins, M.E.4    Buettner, G.R.5    Oberley, L.W.6
  • 85
    • 0035405886 scopus 로고    scopus 로고
    • Metalloproteinases in biology and pathology of the nervous system
    • Yong VW, Power C, Forsyth P, Edwards DR. 2001. Metalloproteinases in biology and pathology of the nervous system. Nat Rev Neurosci 2:502-11.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 502-511
    • Yong, V.W.1    Power, C.2    Forsyth, P.3    Edwards, D.R.4
  • 86
    • 0025363827 scopus 로고
    • Molecular architecture of basement membranes
    • Yurchenco PD, Schittny JC. 1990. Molecular architecture of basement membranes [Review]. FASEB J 4:1577-90.
    • (1990) FASEB J , vol.4 , pp. 1577-1590
    • Yurchenco, P.D.1    Schittny, J.C.2
  • 87
    • 0028298461 scopus 로고
    • Structural and vasoactive factors influencing intracerebral arterioles in cases of vascular dementia and other cerebrovascular disease: A review. Immunohistochemical studies on expression of collagens, basal lamina components and endothelin-1
    • Zhang WW, Badonic T, Hoog A, Jiang MH, Ma KC, Nie JX, and others. 1994. Structural and vasoactive factors influencing intracerebral arterioles in cases of vascular dementia and other cerebrovascular disease: A review. Immunohistochemical studies on expression of collagens, basal lamina components and endothelin-1 [Review]. Dementia 5:153-62.
    • (1994) Dementia , vol.5 , pp. 153-162
    • Zhang, W.W.1    Badonic, T.2    Hoog, A.3    Jiang, M.H.4    Ma, K.C.5    Nie, J.X.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.