Recent advances in artemisinin production through heterologous expression

Current Medicinal Chemistry

Volumn 15, Issue 27, 2008, Pages 2886-2896

  Arsenault, Patrick R ^a   Wobbe, Kristin K ^a   Weathers, Pamela J ^a,b  

^a Worcester Polytechnic Institute   (United States)

^b ARKANSAS STATE UNIVERSITY   (United States)

Author keywords

Amorpha diene; CYP71AV1; Genetic engineering; Malaria; Terpenoid

Indexed keywords

ARTEETHER; ARTEMETHER; ARTEMISIN; ARTEMISIN DERIVATIVE; ARTEMISINIC ACID; ARTEMISININ; ARTESUNATE; CHLOROQUINE; CYTOCHROME P450; DIHYDROARTEMISININ; OXIDOREDUCTASE; SULFADOXINE; ANTIMALARIAL AGENT; ARTEMISININ DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; ARTEMISIA ANNUA; BIOENGINEERING; BIOREACTOR; BIOSYNTHESIS; BREEDING; CATALYSIS; CLINICAL EFFECTIVENESS; CLINICAL TRIAL; COST EFFECTIVENESS ANALYSIS; CYTOSOL; DRUG HALF LIFE; DRUG MANUFACTURE; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; HEALTH CARE COST; HETEROLOGOUS EXPRESSION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MALARIA; NONHUMAN; PLASMODIUM FALCIPARUM; PLASTID; PROCESS OPTIMIZATION; PROTOZOAL INFECTION; REVIEW; SACCHAROMYCES CEREVISIAE; STRUCTURE ACTIVITY RELATION; TRANSGENICS; UVEA MELANOMA; VIRUS INFECTION; GENETICS; METABOLISM; METHODOLOGY; TRANSGENIC PLANT;

ANTIMALARIALS; ARTEMISIA ANNUA; ARTEMISININS; BIOSYNTHETIC PATHWAYS; ESCHERICHIA COLI; GENETIC ENGINEERING; MALARIA; PLANTS, GENETICALLY MODIFIED; SACCHAROMYCES CEREVISIAE;

EID: 58149386641     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986708786242813     Document Type: Review

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