Reaction of artemisinin with haemoglobin: Implications for antimalarial activity

Biochemical Journal

Volumn 385, Issue 2, 2005, Pages 409-418

  Kannan, Rangiah ^a,b   Kumar, Krishan ^b   Sahal, Dinkar ^b   Kukreti, Shrikant ^a   Chauhan, Virander S ^b  

^a UNIVERSITY OF DELHI   (India)

^b International Centre of Genetic Engineering and Biotechnology   (India)

Author keywords

Artemisinin; Haemoglobin; Haemozoin; Plasmodium falciparum histidine rich protein II (PfHRP II); Redox activity

Indexed keywords

ALKYLATION; CHEMICAL REACTIONS; ENZYME INHIBITION; OXIDATION;

ARTEMISININ; ASCORBIC ACID; HAEMOZOIN; PLASMODIUM FASIPARUM HISTIDINE-RICH PROTEIN II (PFHRP II);

DRUG PRODUCTS;

ARTEMISIN; ARTEMISIN DERIVATIVE; ASCORBIC ACID; HEMARTOGLOBIN; HEMOGLOBIN; HEMOZOIN; PLASMODIUM FALCIPARUM HISTIDINE RICH PROTEIN 2; PROTEIN; UNCLASSIFIED DRUG;

ALKYLATION; ANTIMALARIAL ACTIVITY; ARTICLE; CHEMICAL REACTION; DRUG ISOLATION; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG TARGETING; MALARIA; OXIDATION; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; REACTION ANALYSIS;

ALKYLATION; ANIMALS; ANTIMALARIALS; ARTEMISININS; BINDING, COMPETITIVE; HEME; HEMEPROTEINS; HEMOGLOBINS; MYOGLOBIN; OXIDATION-REDUCTION; PLASMODIUM FALCIPARUM; PROTEINS; PROTOZOAN PROTEINS; SESQUITERPENES; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

PLASMODIUM FALCIPARUM; PROTOZOA;

EID: 12844258876     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20041170     Document Type: Article

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