-
1
-
-
84866172561
-
-
World Health Organization Fact sheet N8317 - Cardiovascular diseases
-
World Health Organization (2007) Fact sheet N8317 - Cardiovascular diseases. http://www.who.int/mediacentre/factsheets/fs317/en/index.html.
-
(2007)
-
-
-
2
-
-
0037126526
-
Third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III) final report
-
NCEP Expert Panel
-
NCEP Expert Panel (2002) Third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III) final report. Circulation, 106, 3143-3421.
-
(2002)
Circulation
, vol.106
, pp. 3143-3421
-
-
-
3
-
-
33748039452
-
Heritability of cardiovascular and personality traits in 6
-
Pilia, G., Chen, W.M., Scuteri, A., Orru, M., Albai, G., Dei, M., Lai, S., Usala, G., Lai, M., Loi, P. et al. (2006) Heritability of cardiovascular and personality traits in 6,148 Sardinians. PLoS Genet., 2, e132.
-
(2006)
148 Sardinians. PLoS Genet.
, vol.2
-
-
Pilia, G.1
Chen, W.M.2
Scuteri, A.3
Orru, M.4
Albai, G.5
Dei, M.6
Lai, S.7
Usala, G.8
Lai, M.9
Loi, P.10
-
4
-
-
0031595923
-
A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
-
Deeb, S.S., Fajas, L., Nemoto, M., Pihlajamaki, J., Mykkanen, L., Kuusisto, J., Laakso, M., Fujimoto, W. and Auwerx, J. (1998) A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nat. Genet., 20, 284-287.
-
(1998)
Nat. Genet.
, vol.20
, pp. 284-287
-
-
Deeb, S.S.1
Fajas, L.2
Nemoto, M.3
Pihlajamaki, J.4
Mykkanen, L.5
Kuusisto, J.6
Laakso, M.7
Fujimoto, W.8
Auwerx, J.9
-
5
-
-
0033624575
-
The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
-
Altshuler, D., Hirschhorn, J.N., Klannemark, M., Lindgren, C.M., Vohl, M.C., Nemesh, J., Lane, C.R., Schaffner, S.F., Bolk, S., Brewer, C. et al. (2000) The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat. Genet., 26, 76-80.
-
(2000)
Nat. Genet.
, vol.26
, pp. 76-80
-
-
Altshuler, D.1
Hirschhorn, J.N.2
Klannemark, M.3
Lindgren, C.M.4
Vohl, M.C.5
Nemesh, J.6
Lane, C.R.7
Schaffner, S.F.8
Bolk, S.9
Brewer, C.10
-
6
-
-
0037317981
-
Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes
-
Gloyn, A.L., Weedon, M.N., Owen, K.R., Turner, M.J., Knight, B.A., Hitman, G., Walker, M., Levy, J.C., Sampson, M., Halford, S. et al. (2003) Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes. Diabetes, 52, 568-572.
-
(2003)
Diabetes
, vol.52
, pp. 568-572
-
-
Gloyn, A.L.1
Weedon, M.N.2
Owen, K.R.3
Turner, M.J.4
Knight, B.A.5
Hitman, G.6
Walker, M.7
Levy, J.C.8
Sampson, M.9
Halford, S.10
-
7
-
-
34547536393
-
Common variants in WFS1 confer risk of type 2 diabetes
-
Sandhu, M.S., Weedon, M.N., Fawcett, K.A., Wasson, J., Debenham, S.L., Daly, A., Lango, H., Frayling, T.M., Neumann, R.J., Sherva, R. et al. (2007) Common variants in WFS1 confer risk of type 2 diabetes. Nat. Genet., 39, 951-953.
-
(2007)
Nat. Genet.
, vol.39
, pp. 951-953
-
-
Sandhu, M.S.1
Weedon, M.N.2
Fawcett, K.A.3
Wasson, J.4
Debenham, S.L.5
Daly, A.6
Lango, H.7
Frayling, T.M.8
Neumann, R.J.9
Sherva, R.10
-
8
-
-
33847361938
-
Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes
-
Winckler, W., Weedon, M.N., Graham, R.R., McCarroll, S.A., Purcell, S., Almgren, P., Tuomi, T., Gaudet, D., Bostrom, K.B., Walker, M. et al. (2007) Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes. Diabetes, 56, 685-693.
-
(2007)
Diabetes
, vol.56
, pp. 685-693
-
-
Winckler, W.1
Weedon, M.N.2
Graham, R.R.3
McCarroll, S.A.4
Purcell, S.5
Almgren, P.6
Tuomi, T.7
Gaudet, D.8
Bostrom, K.B.9
Walker, M.10
-
9
-
-
32544451924
-
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
-
Grant, S.F., Thorleifsson, G., Reynisdottir, I., Benediktsson, R., Manolescu, A., Sainz, J., Helgason, A., Stefansson, H., Emilsson, V., Helgadottir, A. et al. (2006) Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat. Genet., 38, 320-323.
-
(2006)
Nat. Genet.
, vol.38
, pp. 320-323
-
-
Grant, S.F.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Manolescu, A.5
Sainz, J.6
Helgason, A.7
Stefansson, H.8
Emilsson, V.9
Helgadottir, A.10
-
10
-
-
33847176604
-
A genome-wide association study identifies novel risk loci for type 2 diabetes
-
Sladek, R., Rocheleau, G., Rung, J., Dina, C., Shen, L., Serre, D., Boutin, P., Vincent, D., Belisle, A., Hadjadj, S. et al. (2007) A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature, 445, 881-885.
-
(2007)
Nature
, vol.445
, pp. 881-885
-
-
Sladek, R.1
Rocheleau, G.2
Rung, J.3
Dina, C.4
Shen, L.5
Serre, D.6
Boutin, P.7
Vincent, D.8
Belisle, A.9
Hadjadj, S.10
-
11
-
-
34249885875
-
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
-
Scott, L.J., Mohlke, K.L., Bonnycastle, L.L., Willer, C.J., Li, Y., Duren, W.L., Erdos, M.R., Stringham, H.M., Chines, P.S., Jackson, A.U. et al. (2007) A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science, 316, 1341-1345.
-
(2007)
Science
, vol.316
, pp. 1341-1345
-
-
Scott, L.J.1
Mohlke, K.L.2
Bonnycastle, L.L.3
Willer, C.J.4
Li, Y.5
Duren, W.L.6
Erdos, M.R.7
Stringham, H.M.8
Chines, P.S.9
Jackson, A.U.10
-
12
-
-
34249888775
-
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
-
Diabetes Genetics Initiative
-
Diabetes Genetics Initiative (2007) Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science, 316, 1331-1336.
-
(2007)
Science
, vol.316
, pp. 1331-1336
-
-
-
13
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Wellcome Trust Case Control Consortium
-
Wellcome Trust Case Control Consortium (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature, 447, 661-678.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
14
-
-
34249895023
-
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
-
Zeggini, E., Weedon, M.N., Lindgren, C.M., Frayling, T.M., Elliott, K.S., Lango, H., Timpson, N.J., Perry, J.R., Rayner, N.W., Freathy, R.M. et al. (2007) Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science, 316, 1336-1341.
-
(2007)
Science
, vol.316
, pp. 1336-1341
-
-
Zeggini, E.1
Weedon, M.N.2
Lindgren, C.M.3
Frayling, T.M.4
Elliott, K.S.5
Lango, H.6
Timpson, N.J.7
Perry, J.R.8
Rayner, N.W.9
Freathy, R.M.10
-
15
-
-
34249828965
-
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes
-
Steinthorsdottir, V., Thorleifsson, G., Reynisdottir, I., Benediktsson, R., Jonsdottir, T., Walters, G.B., Styrkarsdottir, U., Gretarsdottir, S., Emilsson, V., Ghosh, S. et al. (2007) A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat. Genet., 39, 770-775.
-
(2007)
Nat. Genet.
, vol.39
, pp. 770-775
-
-
Steinthorsdottir, V.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Jonsdottir, T.5
Walters, G.B.6
Styrkarsdottir, U.7
Gretarsdottir, S.8
Emilsson, V.9
Ghosh, S.10
-
16
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
Frayling, T.M., Timpson, N.J., Weedon, M.N., Zeggini, E., Freathy, R.M., Lindgren, C.M., Perry, J.R., Elliott, K.S., Lango, H., Rayner, N.W. et al. (2007) A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science, 316, 889-894.
-
(2007)
Science
, vol.316
, pp. 889-894
-
-
Frayling, T.M.1
Timpson, N.J.2
Weedon, M.N.3
Zeggini, E.4
Freathy, R.M.5
Lindgren, C.M.6
Perry, J.R.7
Elliott, K.S.8
Lango, H.9
Rayner, N.W.10
-
17
-
-
34547625955
-
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
-
Scuteri, A., Sanna, S., Chen, W.M., Uda, M., Albai, G., Strait, J., Najjar, S., Nagaraja, R., Orru, M., Usala, G. et al. (2007) Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet., 3, e115.
-
(2007)
PLoS Genet
, vol.3
-
-
Scuteri, A.1
Sanna, S.2
Chen, W.M.3
Uda, M.4
Albai, G.5
Strait, J.6
Najjar, S.7
Nagaraja, R.8
Orru, M.9
Usala, G.10
-
18
-
-
42349106044
-
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
-
Zeggini, E., Scott, L.J., Saxena, R., Voight, B.F., Marchini, J.L., Hu, T., de Bakker, P.I., Abecasis, G.R., Almgren, P., Andersen, G. et al. (2008) Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat. Genet., 40, 638-645.
-
(2008)
Nat. Genet.
, vol.40
, pp. 638-645
-
-
Zeggini, E.1
Scott, L.J.2
Saxena, R.3
Voight, B.F.4
Marchini, J.L.5
Hu, T.6
de Bakker, P.I.7
Abecasis, G.R.8
Almgren, P.9
Andersen, G.10
-
19
-
-
50049119989
-
Association testing of novel type 2 diabetes risk-alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9 and NOTCH2 loci with insulin release, insulin sensitivity and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes
-
Grarup, N., Andersen, G., Krarup, N.T., Albrechtsen, A., Schmitz, O., Jorgensen, T., Borch-Johnsen, K., Hansen, T. and Pedersen, O. (2008) Association testing of novel type 2 diabetes risk-alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9 and NOTCH2 loci with insulin release, insulin sensitivity and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes. Diabetes, 57, 2534-2540.
-
(2008)
Diabetes
, vol.57
, pp. 2534-2540
-
-
Grarup, N.1
Andersen, G.2
Krarup, N.T.3
Albrechtsen, A.4
Schmitz, O.5
Jorgensen, T.6
Borch-Johnsen, K.7
Hansen, T.8
Pedersen, O.9
-
20
-
-
18744407845
-
Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction
-
Ozaki, K., Ohnishi, Y., Iida, A., Sekine, A., Yamada, R., Tsunoda, T., Sato, H., Sato, H., Hori, M., Nakamura, Y. et al. (2002) Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction. Nat. Genet., 32, 650-654.
-
(2002)
Nat. Genet.
, vol.32
, pp. 650-654
-
-
Ozaki, K.1
Ohnishi, Y.2
Iida, A.3
Sekine, A.4
Yamada, R.5
Tsunoda, T.6
Sato, H.7
Sato, H.8
Hori, M.9
Nakamura, Y.10
-
21
-
-
33746597102
-
Lymphotoxin-alpha gene and risk of myocardial infarction in 6,928 cases and 2,712 controls in the ISIS case-control study
-
Clarke, R., Xu, P., Bennett, D., Lewington, S., Zondervan, K., Parish, S., Palmer, A., Clark, S., Cardon, L., Peto, R. et al. (2006) Lymphotoxin-alpha gene and risk of myocardial infarction in 6,928 cases and 2,712 controls in the ISIS case-control study. PLoS Genet., 2, e107.
-
(2006)
PLoS Genet
, vol.2
-
-
Clarke, R.1
Xu, P.2
Bennett, D.3
Lewington, S.4
Zondervan, K.5
Parish, S.6
Palmer, A.7
Clark, S.8
Cardon, L.9
Peto, R.10
-
22
-
-
34250010480
-
A common variant on chromosome 9p21 affects the risk of myocardial infarction
-
Helgadottir, A., Thorleifsson, G., Manolescu, A., Gretarsdottir, S., Blondal, T., Jonasdottir, A., Jonasdottir, A., Sigurdsson, A., Baker, A., Palsson, A. et al. (2007) A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science, 316, 1491-1493.
-
(2007)
Science
, vol.316
, pp. 1491-1493
-
-
Helgadottir, A.1
Thorleifsson, G.2
Manolescu, A.3
Gretarsdottir, S.4
Blondal, T.5
Jonasdottir, A.6
Jonasdottir, A.7
Sigurdsson, A.8
Baker, A.9
Palsson, A.10
-
23
-
-
34249996115
-
A common allele on chromosome 9 associated with coronary heart disease
-
McPherson, R., Pertsemlidis, A., Kavaslar, N., Stewart, A., Roberts, R., Cox, D.R., Hinds, D.A., Pennacchio, L.A., Tybjaerg-Hansen, A., Folsom, A.R. et al. (2007) A common allele on chromosome 9 associated with coronary heart disease. Science, 316, 1488-1491.
-
(2007)
Science
, vol.316
, pp. 1488-1491
-
-
McPherson, R.1
Pertsemlidis, A.2
Kavaslar, N.3
Stewart, A.4
Roberts, R.5
Cox, D.R.6
Hinds, D.A.7
Pennacchio, L.A.8
Tybjaerg-Hansen, A.9
Folsom, A.R.10
-
24
-
-
34447093842
-
A common variant of the p16(INK4a) genetic region is associated with physical function in older people
-
Melzer, D., Frayling, T.M., Murray, A., Hurst, A.J., Harries, L.W., Song, H., Khaw, K., Luben, R., Surtees, P.G., Bandinelli, S.S. et al. (2007) A common variant of the p16(INK4a) genetic region is associated with physical function in older people. Mech. Ageing Dev., 128, 370-377.
-
(2007)
Mech. Ageing Dev.
, vol.128
, pp. 370-377
-
-
Melzer, D.1
Frayling, T.M.2
Murray, A.3
Hurst, A.J.4
Harries, L.W.5
Song, H.6
Khaw, K.7
Luben, R.8
Surtees, P.G.9
Bandinelli, S.S.10
-
25
-
-
33646705144
-
Melanoma genetics: a review of genetic factors and clinical phenotypes in familial melanoma
-
Pho, L., Grossman, D. and Leachman, S.A. (2006) Melanoma genetics: a review of genetic factors and clinical phenotypes in familial melanoma. Curr. Opin. Oncol., 18, 173-179.
-
(2006)
Curr. Opin. Oncol.
, vol.18
, pp. 173-179
-
-
Pho, L.1
Grossman, D.2
Leachman, S.A.3
-
26
-
-
34248547495
-
Characterization of a germ-line deletion, including the entire INK4/ARF locus, in a melanoma-neural system tumor family: identification of ANRIL, an antisense noncoding RNA whose expression coclusters with ARF
-
Pasmant, E., Laurendeau, I., Heron, D., Vidaud, M., Vidaud, D. and Bieche, I. (2007) Characterization of a germ-line deletion, including the entire INK4/ARF locus, in a melanoma-neural system tumor family: identification of ANRIL, an antisense noncoding RNA whose expression coclusters with ARF. Cancer Res., 67, 3963-3969.
-
(2007)
Cancer Res
, vol.67
, pp. 3963-3969
-
-
Pasmant, E.1
Laurendeau, I.2
Heron, D.3
Vidaud, M.4
Vidaud, D.5
Bieche, I.6
-
27
-
-
40549109924
-
Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p
-
Broadbent, H.M., Peden, J.F., Lorkowski, S., Goel, A., Ongen, H., Green, F., Clarke, R., Collins, R., Franzosi, M.G., Tognoni, G. et al. (2008) Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p. Hum. Mol. Genet., 17, 806-814.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 806-814
-
-
Broadbent, H.M.1
Peden, J.F.2
Lorkowski, S.3
Goel, A.4
Ongen, H.5
Green, F.6
Clarke, R.7
Collins, R.8
Franzosi, M.G.9
Tognoni, G.10
-
28
-
-
34547623750
-
Genomewide association analysis of coronary artery disease
-
Samani, N.J., Erdmann, J., Hall, A.S., Hengstenberg, C., Mangino, M., Mayer, B., Dixon, R.J., Meitinger, T., Braund, P., Wichmann, H.E. et al. (2007) Genomewide association analysis of coronary artery disease. N. Engl. J. Med., 357, 443-453.
-
(2007)
N. Engl. J. Med.
, vol.357
, pp. 443-453
-
-
Samani, N.J.1
Erdmann, J.2
Hall, A.S.3
Hengstenberg, C.4
Mangino, M.5
Mayer, B.6
Dixon, R.J.7
Meitinger, T.8
Braund, P.9
Wichmann, H.E.10
-
29
-
-
38649125868
-
Newly identified loci that influence lipid concentrations and risk of coronary artery disease
-
Willer, C.J., Sanna, S., Jackson, A.U., Scuteri, A., Bonnycastle, L.L., Clarke, R., Heath, S.C., Timpson, N.J., Najjar, S.S., Stringham, H.M. et al. (2008) Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat. Genet., 40, 161-169.
-
(2008)
Nat. Genet.
, vol.40
, pp. 161-169
-
-
Willer, C.J.1
Sanna, S.2
Jackson, A.U.3
Scuteri, A.4
Bonnycastle, L.L.5
Clarke, R.6
Heath, S.C.7
Timpson, N.J.8
Najjar, S.S.9
Stringham, H.M.10
-
30
-
-
38649132270
-
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
-
Kathiresan, S., Melander, O., Guiducci, C., Surti, A., Burtt, N.P., Rieder, M.J., Cooper, G.M., Roos, C., Voight, B.F., Havulinna, A.S. et al. (2008) Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat. Genet., 40, 189-197.
-
(2008)
Nat. Genet.
, vol.40
, pp. 189-197
-
-
Kathiresan, S.1
Melander, O.2
Guiducci, C.3
Surti, A.4
Burtt, N.P.5
Rieder, M.J.6
Cooper, G.M.7
Roos, C.8
Voight, B.F.9
Havulinna, A.S.10
-
31
-
-
38849166666
-
LDL-cholesterol concentrations: a genome-wide association study
-
Sandhu, M.S., Waterworth, D.M., Debenham, S.L., Wheeler, E., Papadakis, K., Zhao, J.H., Song, K., Yuan, X., Johnson, T., Ashford, S. et al. (2008) LDL-cholesterol concentrations: a genome-wide association study. Lancet, 371, 483-491.
-
(2008)
Lancet
, vol.371
, pp. 483-491
-
-
Sandhu, M.S.1
Waterworth, D.M.2
Debenham, S.L.3
Wheeler, E.4
Papadakis, K.5
Zhao, J.H.6
Song, K.7
Yuan, X.8
Johnson, T.9
Ashford, S.10
-
32
-
-
38749149611
-
Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia
-
Wallace, C., Newhouse, S.J., Braund, P., Zhang, F., Tobin, M., Falchi, M., Ahmadi, K., Dobson, R.J., Marcano, A.C., Hajat, C. et al. (2008) Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. Am. J. Hum. Genet., 82, 139-149.
-
(2008)
Am. J. Hum. Genet.
, vol.82
, pp. 139-149
-
-
Wallace, C.1
Newhouse, S.J.2
Braund, P.3
Zhang, F.4
Tobin, M.5
Falchi, M.6
Ahmadi, K.7
Dobson, R.J.8
Marcano, A.C.9
Hajat, C.10
-
33
-
-
38649084407
-
Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides
-
Kooner, J.S., Chambers, J.C., Aguilar-Salinas, C.A., Hinds, D.A., Hyde, C.L., Warnes, G.R., Gomez Perez, F.J., Frazer, K.A., Elliott, P., Scott, J. et al. (2008) Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides. Nat. Genet., 40, 149-151.
-
(2008)
Nat. Genet.
, vol.40
, pp. 149-151
-
-
Kooner, J.S.1
Chambers, J.C.2
Aguilar-Salinas, C.A.3
Hinds, D.A.4
Hyde, C.L.5
Warnes, G.R.6
Gomez Perez, F.J.7
Frazer, K.A.8
Elliott, P.9
Scott, J.10
-
34
-
-
33749017409
-
The human obesity gene map: the 2005 update
-
(Silver Spring)
-
Rankinen, T., Zuberi, A., Chagnon, Y.C., Weisnagel, S.J., Argyropoulos, G., Walts, B., Perusse, L. and Bouchard, C. (2006) The human obesity gene map: the 2005 update. Obesity (Silver Spring), 14, 529-644.
-
(2006)
Obesity
, vol.14
, pp. 529-644
-
-
Rankinen, T.1
Zuberi, A.2
Chagnon, Y.C.3
Weisnagel, S.J.4
Argyropoulos, G.5
Walts, B.6
Perusse, L.7
Bouchard, C.8
-
35
-
-
48349113289
-
Common nonsynonymous variants in PCSK1 confer risk of obesity
-
Benzinou, M., Creemers, J.W., Choquet, H., Lobbens, S., Dina, C., Durand, E., Guerardel, A., Boutin, P., Jouret, B., Heude, B. et al. (2008) Common nonsynonymous variants in PCSK1 confer risk of obesity. Nat. Genet., 40, 943-945.
-
(2008)
Nat. Genet.
, vol.40
, pp. 943-945
-
-
Benzinou, M.1
Creemers, J.W.2
Choquet, H.3
Lobbens, S.4
Dina, C.5
Durand, E.6
Guerardel, A.7
Boutin, P.8
Jouret, B.9
Heude, B.10
-
36
-
-
33645825830
-
A common genetic variant is associated with adult and childhood obesity
-
Herbert, A., Gerry, N.P., McQueen, M.B., Heid, I.M., Pfeufer, A., Illig, T., Wichmann, H.E., Meitinger, T., Hunter, D., Hu, F.B. et al. (2006) A common genetic variant is associated with adult and childhood obesity. Science, 312, 279-283.
-
(2006)
Science
, vol.312
, pp. 279-283
-
-
Herbert, A.1
Gerry, N.P.2
McQueen, M.B.3
Heid, I.M.4
Pfeufer, A.5
Illig, T.6
Wichmann, H.E.7
Meitinger, T.8
Hunter, D.9
Hu, F.B.10
-
37
-
-
34247576412
-
The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts
-
Lyon, H.N., Emilsson, V., Hinney, A., Heid, I.M., Lasky-Su, J., Zhu, X., Thorleifsson, G., Gunnarsdottir, S., Walters, G.B., Thorsteinsdottir, U. et al. (2007) The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts. PLoS Genet., 3, e61.
-
(2007)
PLoS Genet
, vol.3
-
-
Lyon, H.N.1
Emilsson, V.2
Hinney, A.3
Heid, I.M.4
Lasky-Su, J.5
Zhu, X.6
Thorleifsson, G.7
Gunnarsdottir, S.8
Walters, G.B.9
Thorsteinsdottir, U.10
-
38
-
-
34249777814
-
Variation in FTO contributes to childhood obesity and severe adult obesity
-
Dina, C., Meyre, D., Gallina, S., Durand, E., Korner, A., Jacobson, P., Carlsson, L.M., Kiess, W., Vatin, V., Lecoeur, C. et al. (2007) Variation in FTO contributes to childhood obesity and severe adult obesity. Nat. Genet., 39, 724-726.
-
(2007)
Nat. Genet.
, vol.39
, pp. 724-726
-
-
Dina, C.1
Meyre, D.2
Gallina, S.3
Durand, E.4
Korner, A.5
Jacobson, P.6
Carlsson, L.M.7
Kiess, W.8
Vatin, V.9
Lecoeur, C.10
-
39
-
-
36749041363
-
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase
-
Gerken, T., Girard, C.A., Tung, Y.C., Webby, C.J., Saudek, V., Hewitson, K.S., Yeo, G.S., McDonough, M.A., Cunliffe, S., McNeill, L.A. et al. (2007) The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science, 318, 1469-1472.
-
(2007)
Science
, vol.318
, pp. 1469-1472
-
-
Gerken, T.1
Girard, C.A.2
Tung, Y.C.3
Webby, C.J.4
Saudek, V.5
Hewitson, K.S.6
Yeo, G.S.7
McDonough, M.A.8
Cunliffe, S.9
McNeill, L.A.10
-
40
-
-
44349142294
-
Common variants near MC4R are associated with fat mass, weight and risk of obesity
-
Loos, R.J., Lindgren, C.M., Li, S., Wheeler, E., Zhao, J.H., Prokopenko, I., Inouye, M., Freathy, R.M., Attwood, A.P., Beckmann, J.S. et al. (2008) Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat. Genet., 40, 768-775.
-
(2008)
Nat. Genet.
, vol.40
, pp. 768-775
-
-
Loos, R.J.1
Lindgren, C.M.2
Li, S.3
Wheeler, E.4
Zhao, J.H.5
Prokopenko, I.6
Inouye, M.7
Freathy, R.M.8
Attwood, A.P.9
Beckmann, J.S.10
-
41
-
-
44349166252
-
Common genetic variation near MC4R is associated with waist circumference and insulin resistance
-
Chambers, J.C., Elliott, P., Zabaneh, D., Zhang, W., Li, Y., Froguel, P., Balding, D., Scott, J. and Kooner, J.S. (2008) Common genetic variation near MC4R is associated with waist circumference and insulin resistance. Nat. Genet., 40, 716-718.
-
(2008)
Nat. Genet.
, vol.40
, pp. 716-718
-
-
Chambers, J.C.1
Elliott, P.2
Zabaneh, D.3
Zhang, W.4
Li, Y.5
Froguel, P.6
Balding, D.7
Scott, J.8
Kooner, J.S.9
-
42
-
-
44849086097
-
Genome-wide association scans identified CTNNBL1 as a novel gene for obesity
-
Liu, Y.J., Liu, X.G., Wang, L., Dina, C., Yan, H., Liu, J.F., Levy, S., Papasian, C.J., Drees, B.M., Hamilton, J.J. et al. (2008) Genome-wide association scans identified CTNNBL1 as a novel gene for obesity. Hum. Mol. Genet., 17, 1803-1813.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 1803-1813
-
-
Liu, Y.J.1
Liu, X.G.2
Wang, L.3
Dina, C.4
Yan, H.5
Liu, J.F.6
Levy, S.7
Papasian, C.J.8
Drees, B.M.9
Hamilton, J.J.10
-
43
-
-
0032714352
-
Genomic control for association studies
-
Devlin, B. and Roeder, K. (1999) Genomic control for association studies. Biometrics, 55, 997-1004.
-
(1999)
Biometrics
, vol.55
, pp. 997-1004
-
-
Devlin, B.1
Roeder, K.2
-
44
-
-
33745237158
-
A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization
-
Arking, D.E., Pfeufer, A., Post, W., Kao, W.H., Newton-Cheh, C., Ikeda, M., West, K., Kashuk, C., Akyol, M., Perz, S. et al. (2006) A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization. Nat. Genet., 38, 644-651.
-
(2006)
Nat. Genet.
, vol.38
, pp. 644-651
-
-
Arking, D.E.1
Pfeufer, A.2
Post, W.3
Kao, W.H.4
Newton-Cheh, C.5
Ikeda, M.6
West, K.7
Kashuk, C.8
Akyol, M.9
Perz, S.10
-
45
-
-
33845220776
-
A common haplotype of the glucokinase gene alters fasting glucose and birth weight: association in six studies and population-genetics analyses
-
Weedon, M.N., Clark, V.J., Qian, Y., Ben-Shlomo, Y., Timpson, N., Ebrahim, S., Lawlor, D.A., Pembrey, M.E., Ring, S., Wilkin, T.J. et al. (2006) A common haplotype of the glucokinase gene alters fasting glucose and birth weight: association in six studies and population-genetics analyses. Am. J. Hum. Genet., 79, 991-1001.
-
(2006)
Am. J. Hum. Genet.
, vol.79
, pp. 991-1001
-
-
Weedon, M.N.1
Clark, V.J.2
Qian, Y.3
Ben-Shlomo, Y.4
Timpson, N.5
Ebrahim, S.6
Lawlor, D.A.7
Pembrey, M.E.8
Ring, S.9
Wilkin, T.J.10
-
46
-
-
46749100599
-
Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels
-
Chen, W.M., Erdos, M.R., Jackson, A.U., Saxena, R., Sanna, S., Silver, K.D., Timpson, N.J., Hansen, T., Orru, M., Grazia Piras, M. et al. (2008) Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. J. Clin. Invest, 118, 2620-2628.
-
(2008)
J. Clin. Invest
, vol.118
, pp. 2620-2628
-
-
Chen, W.M.1
Erdos, M.R.2
Jackson, A.U.3
Saxena, R.4
Sanna, S.5
Silver, K.D.6
Timpson, N.J.7
Hansen, T.8
Orru, M.9
Grazia Piras, M.10
-
47
-
-
44449091627
-
A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels
-
Bouatia-Naji, N., Rocheleau, G., Van Lommel, L., Lemaire, K., Schuit, F., Cavalcanti-Proenca, C., Marchand, M., Hartikainen, A.L., Sovio, U., De Graeve, F. et al. (2008) A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels. Science, 320, 1085-1088.
-
(2008)
Science
, vol.320
, pp. 1085-1088
-
-
Bouatia-Naji, N.1
Rocheleau, G.2
Van Lommel, L.3
Lemaire, K.4
Schuit, F.5
Cavalcanti-Proenca, C.6
Marchand, M.7
Hartikainen, A.L.8
Sovio, U.9
De Graeve, F.10
-
48
-
-
37349008492
-
The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts
-
Li, S., Sanna, S., Maschio, A., Busonero, F., Usala, G., Mulas, A., Lai, S., Dei, M., Orru, M., Albai, G. et al. (2007) The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts. PLoS Genet., 3, e194.
-
(2007)
PLoS Genet
, vol.3
-
-
Li, S.1
Sanna, S.2
Maschio, A.3
Busonero, F.4
Usala, G.5
Mulas, A.6
Lai, S.7
Dei, M.8
Orru, M.9
Albai, G.10
-
49
-
-
41449093735
-
SLC2A9 influences uric acid concentrations with pronounced sex-specific effects
-
Doring, A., Gieger, C., Mehta, D., Gohlke, H., Prokisch, H., Coassin, S., Fischer, G., Henke, K., Klopp, N., Kronenberg, F. et al. (2008) SLC2A9 influences uric acid concentrations with pronounced sex-specific effects. Nat. Genet., 40, 430-436.
-
(2008)
Nat. Genet.
, vol.40
, pp. 430-436
-
-
Doring, A.1
Gieger, C.2
Mehta, D.3
Gohlke, H.4
Prokisch, H.5
Coassin, S.6
Fischer, G.7
Henke, K.8
Klopp, N.9
Kronenberg, F.10
-
50
-
-
41349103917
-
SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout
-
Vitart, V., Rudan, I., Hayward, C., Gray, N.K., Floyd, J., Palmer, C.N., Knott, S.A., Kolcic, I., Polasek, O., Graessler, J. et al. (2008) SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout. Nat. Genet., 40, 437-442.
-
(2008)
Nat. Genet.
, vol.40
, pp. 437-442
-
-
Vitart, V.1
Rudan, I.2
Hayward, C.3
Gray, N.K.4
Floyd, J.5
Palmer, C.N.6
Knott, S.A.7
Kolcic, I.8
Polasek, O.9
Graessler, J.10
-
51
-
-
42749083781
-
Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein
-
Reiner, A.P., Barber, M.J., Guan, Y., Ridker, P.M., Lange, L.A., Chasman, D.I., Walston, J.D., Cooper, G.M., Jenny, N.S., Rieder, M.J. et al. (2008) Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein. Am. J. Hum. Genet., 82, 1193-1201.
-
(2008)
Am. J. Hum. Genet.
, vol.82
, pp. 1193-1201
-
-
Reiner, A.P.1
Barber, M.J.2
Guan, Y.3
Ridker, P.M.4
Lange, L.A.5
Chasman, D.I.6
Walston, J.D.7
Cooper, G.M.8
Jenny, N.S.9
Rieder, M.J.10
-
52
-
-
42749092252
-
Loci related to metabolic-syndrome pathways including LEPR, HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study
-
Ridker, P.M., Pare, G., Parker, A., Zee, R.Y., Danik, J.S., Buring, J.E., Kwiatkowski, D., Cook, N.R., Miletich, J.P. and Chasman, D.I. (2008) Loci related to metabolic-syndrome pathways including LEPR, HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study. Am. J. Hum. Genet., 82, 1185-1192.
-
(2008)
Am. J. Hum. Genet.
, vol.82
, pp. 1185-1192
-
-
Ridker, P.M.1
Pare, G.2
Parker, A.3
Zee, R.Y.4
Danik, J.S.5
Buring, J.E.6
Kwiatkowski, D.7
Cook, N.R.8
Miletich, J.P.9
Chasman, D.I.10
-
53
-
-
40949149395
-
Polymorphisms associated with cholesterol and risk of cardiovascular events
-
Kathiresan, S., Melander, O., Anevski, D., Guiducci, C., Burtt, N.P., Roos, C., Hirschhorn, J.N., Berglund, G., Hedblad, B., Groop, L. et al. (2008) Polymorphisms associated with cholesterol and risk of cardiovascular events. N. Engl. J. Med, 358, 1240-1249.
-
(2008)
N. Engl. J. Med
, vol.358
, pp. 1240-1249
-
-
Kathiresan, S.1
Melander, O.2
Anevski, D.3
Guiducci, C.4
Burtt, N.P.5
Roos, C.6
Hirschhorn, J.N.7
Berglund, G.8
Hedblad, B.9
Groop, L.10
|