메뉴 건너뛰기




Volumn 118, Issue 7, 2008, Pages 2620-2628

Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels

(51)  Chen, Wei Min a,b   Erdos, Michael R c   Jackson, Anne U d   Saxena, Richa e   Sanna, Serena d,f   Silver, Kristi D g   Timpson, Nicholas J h   Hansen, Torben i   Orrù, Marco f   Piras, Maria Grazia f   Bonnycastle, Lori L c   Wilier, Cristen J d   Lyssenko, Valeriya j   Shen, Haiqing g   Kuusisto, Johanna k   Ebrahim, Shah l   Sestu, Natascia m   Duren, William L d   Spada, Maria Cristina f   Stringham, Heather M d   more..

f CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; GLUCOSE 6 PHOSPHATASE;

EID: 46749100599     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JC134566     Document Type: Article
Times cited : (144)

References (68)
  • 1
    • 0024160877 scopus 로고
    • Role of insulin resistance in human disease
    • Reaven, G.M. 1988. Role of insulin resistance in human disease. Diabetes. 37:1595-1607.
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.M.1
  • 2
    • 0024026298 scopus 로고
    • The triumvirate: B-cell, muscle, liver. A collusion responsible for NIDDM
    • DeFronzo, R.A. 1987. The triumvirate: B-cell, muscle, liver. A collusion responsible for NIDDM. Diabetes. 37:667-687.
    • (1987) Diabetes , vol.37 , pp. 667-687
    • DeFronzo, R.A.1
  • 3
    • 0018602014 scopus 로고
    • Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance
    • National Diabetes Data Group
    • National Diabetes Data Group. 1979. Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes. 28:1039-1057.
    • (1979) Diabetes , vol.28 , pp. 1039-1057
  • 4
    • 0021776150 scopus 로고
    • Diabetes Mellitus: Report of a WHO Study Group
    • World Health Organ. Tech. Rep. Ser
    • [No authors listed]. 1985. Diabetes Mellitus: Report of a WHO Study Group. World Health Organ. Tech. Rep. Ser. 727:1-113.
    • (1985) , vol.727 , pp. 1-113
  • 5
    • 1842334456 scopus 로고    scopus 로고
    • Report of the expert committee on the diagnosis and classification of diabetes mellitus
    • The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
    • The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. 1997. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care. 20:1183-1197.
    • (1997) Diabetes Care , vol.20 , pp. 1183-1197
  • 6
    • 0026021161 scopus 로고
    • Insulin resistance: A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease
    • DeFronzo, R.A., and Ferrannini, E. 1991. Insulin resistance: A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care. 14:173-194.
    • (1991) Diabetes Care , vol.14 , pp. 173-194
    • DeFronzo, R.A.1    Ferrannini, E.2
  • 7
    • 33745313440 scopus 로고    scopus 로고
    • Coordinate changes in plasma glucose and pancreatic β-cell function in Latino women at high risk for type 2 diabetes
    • Xiang, A.H., et al. 2006. Coordinate changes in plasma glucose and pancreatic β-cell function in Latino women at high risk for type 2 diabetes. Diabetes. 55:1074-1079.
    • (2006) Diabetes , vol.55 , pp. 1074-1079
    • Xiang, A.H.1
  • 8
    • 34547599640 scopus 로고    scopus 로고
    • Progression to type 2 diabetes characterized by moderate then rapid glucose increases
    • Mason, C.C., Hanson, R.L., and Knowler, W.C. 2007. Progression to type 2 diabetes characterized by moderate then rapid glucose increases. Diabetes. 56:2054-2061.
    • (2007) Diabetes , vol.56 , pp. 2054-2061
    • Mason, C.C.1    Hanson, R.L.2    Knowler, W.C.3
  • 9
    • 0025094344 scopus 로고
    • Mapping genes in diabetes
    • Rich, S.S. 1990. Mapping genes in diabetes. Diabetes. 39:1315-1319.
    • (1990) Diabetes , vol.39 , pp. 1315-1319
    • Rich, S.S.1
  • 10
    • 0030031579 scopus 로고    scopus 로고
    • Genetic analysis of NIDDM: The study of quantitative traits
    • Ghosh, S., and Schork, N.J. 1996. Genetic analysis of NIDDM: the study of quantitative traits. Diabetes. 45:1-14.
    • (1996) Diabetes , vol.45 , pp. 1-14
    • Ghosh, S.1    Schork, N.J.2
  • 11
    • 0037034257 scopus 로고    scopus 로고
    • Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    • Diabetes Prevention Program Research Group
    • Diabetes Prevention Program Research Group. 2002. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N. Engl. J. Med. 346:393-403.
    • (2002) N. Engl. J. Med , vol.346 , pp. 393-403
  • 12
    • 0035799806 scopus 로고    scopus 로고
    • Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance
    • Tuomilehto, J., et al. 2001. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N. Engl. J. Med. 344:1343-1350.
    • (2001) N. Engl. J. Med , vol.344 , pp. 1343-1350
    • Tuomilehto, J.1
  • 13
    • 34249888775 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
    • Diabetes Genetics Initiative of Broad Institute of Harvard and MIT
    • Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, et al. 2007. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science. 316:1331-1336.
    • (2007) Science , vol.316 , pp. 1331-1336
  • 14
    • 34249885875 scopus 로고    scopus 로고
    • A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
    • Scott, L.J., et al. 2007. A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science. 316:1341-1345.
    • (2007) Science , vol.316 , pp. 1341-1345
    • Scott, L.J.1
  • 15
    • 34249895023 scopus 로고    scopus 로고
    • Replication of genome-wide association signals in U.K. samples reveals risk loci for type 2 diabetes
    • Zeggini, E., et al. 2007. Replication of genome-wide association signals in U.K. samples reveals risk loci for type 2 diabetes. Science. 316:1336-1341.
    • (2007) Science , vol.316 , pp. 1336-1341
    • Zeggini, E.1
  • 16
    • 33847176604 scopus 로고    scopus 로고
    • A genome-wide association study identified novel risk loci for type 2 diabetes
    • Sladek, R., et al. 2007. A genome-wide association study identified novel risk loci for type 2 diabetes. Nature. 445:881-885.
    • (2007) Nature , vol.445 , pp. 881-885
    • Sladek, R.1
  • 17
    • 34249828965 scopus 로고    scopus 로고
    • A variant in CDKAL1 influences insulin response and risk of type 2 diabetes
    • Steinthorsdottir, V., et al. 2007. A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat. Genet. 39:770-775.
    • (2007) Nat. Genet , vol.39 , pp. 770-775
    • Steinthorsdottir, V.1
  • 18
    • 42349106044 scopus 로고    scopus 로고
    • Meta-analysis of genomewide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
    • Zeggini, E., et al. 2008. Meta-analysis of genomewide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat. Genet. 40:638-645.
    • (2008) Nat. Genet , vol.40 , pp. 638-645
    • Zeggini, E.1
  • 19
    • 0019906750 scopus 로고
    • Estimating genetic and non-genetic components of variance for fasting glucose levels in pedigrees ascertained through non-insulin dependent diabetes
    • Beaty, T.H., and Fajans, S.S. 1982. Estimating genetic and non-genetic components of variance for fasting glucose levels in pedigrees ascertained through non-insulin dependent diabetes. Ann. Hum. Genet. 46:355-362.
    • (1982) Ann. Hum. Genet , vol.46 , pp. 355-362
    • Beaty, T.H.1    Fajans, S.S.2
  • 20
    • 0023132190 scopus 로고
    • Partitioning the variability of fasting plasma glucose levels in pedigrees
    • Boehnke, M., Moll, P.P., Kottke, B.A., and Weidman, W.H. 1987. Partitioning the variability of fasting plasma glucose levels in pedigrees. Am. J. Epidemiol. 125:679-689.
    • (1987) Am. J. Epidemiol , vol.125 , pp. 679-689
    • Boehnke, M.1    Moll, P.P.2    Kottke, B.A.3    Weidman, W.H.4
  • 21
    • 0031016728 scopus 로고    scopus 로고
    • Familiality of physical and metabolic characteristics that predict the development of non-insulin-dependent diabetes mellitus in Pima Indians
    • Sakul, H., et al. 1997. Familiality of physical and metabolic characteristics that predict the development of non-insulin-dependent diabetes mellitus in Pima Indians. Am. J. Hum. Genet. 60:651-656.
    • (1997) Am. J. Hum. Genet , vol.60 , pp. 651-656
    • Sakul, H.1
  • 22
    • 0032980306 scopus 로고    scopus 로고
    • Familiality of quantitative metabolic traits in Finnish families with non-insulin-dependent diabetes mellitus
    • Watanabe, R.M., et al. 1999. Familiality of quantitative metabolic traits in Finnish families with non-insulin-dependent diabetes mellitus. Hum. Hered. 49:159-168.
    • (1999) Hum. Hered , vol.49 , pp. 159-168
    • Watanabe, R.M.1
  • 23
    • 12244274329 scopus 로고    scopus 로고
    • Genetic epidemiology of insulin resistance and visceral adiposity. The IRAS family study design and methods
    • Henkin, L., et al. 2003. Genetic epidemiology of insulin resistance and visceral adiposity. The IRAS family study design and methods. Ann. Epidemiol. 13:211-217.
    • (2003) Ann. Epidemiol , vol.13 , pp. 211-217
    • Henkin, L.1
  • 24
    • 33748039452 scopus 로고    scopus 로고
    • Heritability of cardiovascular and personality traits in 6,148 Sardinians
    • Pilia, G., et al. 2006. Heritability of cardiovascular and personality traits in 6,148 Sardinians. PLoS Genet. 2:e132.
    • (2006) PLoS Genet , vol.2
    • Pilia, G.1
  • 25
    • 33845220776 scopus 로고    scopus 로고
    • A common haplotype of the glucokinase gene alters fasting glucose and birth weight: Association in six studies and population-genetics analyses
    • Weedon, M.N., et al. 2006. A common haplotype of the glucokinase gene alters fasting glucose and birth weight: Association in six studies and population-genetics analyses. Am. J. Hum. Genet. 79:991-1001.
    • (2006) Am. J. Hum. Genet , vol.79 , pp. 991-1001
    • Weedon, M.N.1
  • 26
    • 3643136390 scopus 로고    scopus 로고
    • Mapping genes for NIDDM. Design of the Finland-United States Investigation of NIDDM Genetics (FUSION) Study
    • Valle, T., et al. 1998. Mapping genes for NIDDM. Design of the Finland-United States Investigation of NIDDM Genetics (FUSION) Study. Diabetes Care. 21:949-958.
    • (1998) Diabetes Care , vol.21 , pp. 949-958
    • Valle, T.1
  • 27
    • 10744226236 scopus 로고    scopus 로고
    • A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14
    • Silander, K., et al. 2004. A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14. Diabetes. 53:821-829.
    • (2004) Diabetes , vol.53 , pp. 821-829
    • Silander, K.1
  • 28
    • 34547625955 scopus 로고    scopus 로고
    • Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
    • Scuteri, A., et al. 2007. Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet. 3:1200-1210.
    • (2007) PLoS Genet , vol.3 , pp. 1200-1210
    • Scuteri, A.1
  • 29
    • 17744383578 scopus 로고    scopus 로고
    • Genome-wide scan of obesity in the Old Order Amish
    • Hsueh, W.-C., et al. 2001. Genome-wide scan of obesity in the Old Order Amish. J. Clin. Endocrinol. Metab. 86:1199-1205.
    • (2001) J. Clin. Endocrinol. Metab , vol.86 , pp. 1199-1205
    • Hsueh, W.-C.1
  • 30
    • 11144276583 scopus 로고    scopus 로고
    • Exploring the genetics of longevity in the Old Order Amish
    • Sorkin, J., et al. 2005. Exploring the genetics of longevity in the Old Order Amish. Mech. Ageing Dev. 126:347-350.
    • (2005) Mech. Ageing Dev , vol.126 , pp. 347-350
    • Sorkin, J.1
  • 31
    • 34447128922 scopus 로고    scopus 로고
    • Associations between genetic variants in the NOS1AP (CAPON) gene and cardiac repolarization in the Old Order Amish
    • Post, W., et al. 2007. Associations between genetic variants in the NOS1AP (CAPON) gene and cardiac repolarization in the Old Order Amish. Hum. Hered. 64:214-219.
    • (2007) Hum. Hered , vol.64 , pp. 214-219
    • Post, W.1
  • 32
    • 0021173999 scopus 로고
    • Caerphilly and Speedwell collaborative heart disease studies
    • The Caerphilly and Speedwell Collaborative Group
    • The Caerphilly and Speedwell Collaborative Group. 1984. Caerphilly and Speedwell collaborative heart disease studies. J. Epidemiol. Community Health. 38:259-262.
    • (1984) J. Epidemiol. Community Health , vol.38 , pp. 259-262
  • 33
    • 0037310332 scopus 로고    scopus 로고
    • Geographical variation in cardiovascular disease, risk factors, and their control in older women: British Women's Heart and Health Study
    • Lawlor, D., Bedford, C., Taylor, M., and Ebrahim, S. 2003. Geographical variation in cardiovascular disease, risk factors, and their control in older women: British Women's Heart and Health Study. J. Epidemiol. Community Health. 57:134-140.
    • (2003) J. Epidemiol. Community Health , vol.57 , pp. 134-140
    • Lawlor, D.1    Bedford, C.2    Taylor, M.3    Ebrahim, S.4
  • 34
    • 0347511013 scopus 로고    scopus 로고
    • Obesity and central fat pattern among Greenland Inuit and a general population of Denmark (Inter99): Relationship to metabolic risk factors
    • Jørgensen, M.E., et al. 2003. Obesity and central fat pattern among Greenland Inuit and a general population of Denmark (Inter99): relationship to metabolic risk factors. Int. J. Obes. Relat. Metab. Disord. 27:1507-1515.
    • (2003) Int. J. Obes. Relat. Metab. Disord , vol.27 , pp. 1507-1515
    • Jørgensen, M.E.1
  • 35
    • 17644434640 scopus 로고    scopus 로고
    • Glümer, C., Jørgensen, T., Borch-Johnsen, K., and Inter99 study. 2003. Prevalences of diabetes and impaired glucose regulation in a Danish population: the Inter99 study. Diabetes Care. 26:2335-2340.
    • Glümer, C., Jørgensen, T., Borch-Johnsen, K., and Inter99 study. 2003. Prevalences of diabetes and impaired glucose regulation in a Danish population: the Inter99 study. Diabetes Care. 26:2335-2340.
  • 36
    • 11144356677 scopus 로고    scopus 로고
    • Enzymatic characterization of the pancreatic islet-specific glucose-6-phosphatase-related protein (IGRP)
    • Petrolonis, A.J., et al. 2004. Enzymatic characterization of the pancreatic islet-specific glucose-6-phosphatase-related protein (IGRP). J. Biol. Chem. 279:13976-13983.
    • (2004) J. Biol. Chem , vol.279 , pp. 13976-13983
    • Petrolonis, A.J.1
  • 37
    • 24944508637 scopus 로고    scopus 로고
    • In islet-specific glucose-6-phosphatase-related protein, the beta cell antigenic sequence that is targeted in diabetes is not responsible for the loss of phosphohydrolase activity
    • Shieh, J.-J., Pan, C.-J., Mansfield, B.C., and Chou, J.Y. 2005. In islet-specific glucose-6-phosphatase-related protein, the beta cell antigenic sequence that is targeted in diabetes is not responsible for the loss of phosphohydrolase activity. Diabetologia. 48:1851-1859.
    • (2005) Diabetologia , vol.48 , pp. 1851-1859
    • Shieh, J.-J.1    Pan, C.-J.2    Mansfield, B.C.3    Chou, J.Y.4
  • 38
    • 4143073631 scopus 로고    scopus 로고
    • Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11
    • van Mil, S.W.C., et al. 2004. Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11. Gastroenterology. 127:379-384.
    • (2004) Gastroenterology , vol.127 , pp. 379-384
    • van Mil, S.W.C.1
  • 39
    • 33846589652 scopus 로고    scopus 로고
    • Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 assocaited with drug-induced liver injury
    • Lang, C., et al. 2007. Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 assocaited with drug-induced liver injury. Pharmacogenet. Genomics. 17:47-60.
    • (2007) Pharmacogenet. Genomics , vol.17 , pp. 47-60
    • Lang, C.1
  • 40
    • 0032714352 scopus 로고    scopus 로고
    • Genomic control for association studies
    • Devlin, B., and Roeder, K. 1999. Genomic control for association studies. Biometrics. 55:997-1004.
    • (1999) Biometrics , vol.55 , pp. 997-1004
    • Devlin, B.1    Roeder, K.2
  • 41
    • 0035126136 scopus 로고    scopus 로고
    • Cholestatic potential of troglitazone as a possible factor contributing to troglitazoneinduced hepatotoxicity: In vivo and in vitro interaction at the canalicular bile salt export pump (Bsep) in the rat
    • Funk, C., Ponelle, C., Scheuermann, G., and Pantze, M. 2001. Cholestatic potential of troglitazone as a possible factor contributing to troglitazoneinduced hepatotoxicity: in vivo and in vitro interaction at the canalicular bile salt export pump (Bsep) in the rat. Mol. Pharmacol. 59:627-635.
    • (2001) Mol. Pharmacol , vol.59 , pp. 627-635
    • Funk, C.1    Ponelle, C.2    Scheuermann, G.3    Pantze, M.4
  • 42
    • 34347401852 scopus 로고    scopus 로고
    • Bile acid sequestrants and the treatment of type 2 diabetes mellitus
    • Staels, B., and Kuipers, F. 2007. Bile acid sequestrants and the treatment of type 2 diabetes mellitus. Drugs. 67:1383-1392.
    • (2007) Drugs , vol.67 , pp. 1383-1392
    • Staels, B.1    Kuipers, F.2
  • 43
    • 17844365884 scopus 로고    scopus 로고
    • Identification of CD4+ T cell-specific epitopes of islet-specific glucose-6-phosphatase catalytic subunit-related protein: A novel beta cell autoantigen in type 1 diabetes
    • Mukherjee, R., Wagar, D., Stephens, T.A., Lee-Chan, E., and Singh, B. 2005. Identification of CD4+ T cell-specific epitopes of islet-specific glucose-6-phosphatase catalytic subunit-related protein: a novel beta cell autoantigen in type 1 diabetes. J. Immunol. 174:5306-5315.
    • (2005) J. Immunol , vol.174 , pp. 5306-5315
    • Mukherjee, R.1    Wagar, D.2    Stephens, T.A.3    Lee-Chan, E.4    Singh, B.5
  • 44
    • 33847620145 scopus 로고    scopus 로고
    • Deletion of the gene encoding the islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen results in a mild metabolic phenotype
    • Wang, Y., et al. 2007. Deletion of the gene encoding the islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen results in a mild metabolic phenotype. Diabetologia. 50:774-778.
    • (2007) Diabetologia , vol.50 , pp. 774-778
    • Wang, Y.1
  • 45
    • 0033048175 scopus 로고    scopus 로고
    • Molecular cloning of a pancreatic islet-specific glucose-6-phosphatase cataliytic subunit-related protein
    • Arden, S.D., et al. 1999. Molecular cloning of a pancreatic islet-specific glucose-6-phosphatase cataliytic subunit-related protein. Diabetes. 48:531-542.
    • (1999) Diabetes , vol.48 , pp. 531-542
    • Arden, S.D.1
  • 46
    • 1642325818 scopus 로고    scopus 로고
    • The islet-specific glucose-6-phosphatase-related protein, implicated in diabetes, is a glyco-protein embedded in the endoplasmic reticulum membrane
    • Shieh, J.-J., Pan, C.-J., Mansfield, B.C., and Chou, J.Y. 2004. The islet-specific glucose-6-phosphatase-related protein, implicated in diabetes, is a glyco-protein embedded in the endoplasmic reticulum membrane. FEBS Lett. 562:160-164.
    • (2004) FEBS Lett , vol.562 , pp. 160-164
    • Shieh, J.-J.1    Pan, C.-J.2    Mansfield, B.C.3    Chou, J.Y.4
  • 47
    • 33646417368 scopus 로고    scopus 로고
    • Alternative splicing of G6PC2, the gene coding for the islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP), results in differential expression in human thymus and spleen compared with pancreas
    • Dogra, R.S., et al. 2006. Alternative splicing of G6PC2, the gene coding for the islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP), results in differential expression in human thymus and spleen compared with pancreas. Diabetologia. 49:953-957.
    • (2006) Diabetologia , vol.49 , pp. 953-957
    • Dogra, R.S.1
  • 49
    • 0025278457 scopus 로고
    • Glucose cycling in islets from healthy and diabetic rats
    • Khan, A., et al. 1990. Glucose cycling in islets from healthy and diabetic rats. Diabetes. 39:456-459.
    • (1990) Diabetes , vol.39 , pp. 456-459
    • Khan, A.1
  • 50
    • 0024356180 scopus 로고
    • Evidence for the presence of glucose cycling in pancreatic islets of the ob/ob mouse
    • Khan, A., et al. 1989. Evidence for the presence of glucose cycling in pancreatic islets of the ob/ob mouse. J. Biol. Chem. 264:9732- 9733.
    • (1989) J. Biol. Chem , vol.264 , pp. 9732-9733
    • Khan, A.1
  • 51
    • 0025299154 scopus 로고
    • Glucose cycling is markedly enhanced in pancreatic islets of obese hyperglycemic mice
    • Khan, A., et al. 1990. Glucose cycling is markedly enhanced in pancreatic islets of obese hyperglycemic mice. Endocrinology. 126:2413-2416.
    • (1990) Endocrinology , vol.126 , pp. 2413-2416
    • Khan, A.1
  • 52
    • 0034644780 scopus 로고    scopus 로고
    • Glucose regulation of gene transcription
    • Vaulont, S., Vasseur-Cognet, M., and Kahn, A. 2000. Glucose regulation of gene transcription. J. Biol. Chem. 275:31555-31558.
    • (2000) J. Biol. Chem , vol.275 , pp. 31555-31558
    • Vaulont, S.1    Vasseur-Cognet, M.2    Kahn, A.3
  • 53
    • 0028020729 scopus 로고
    • Glucokinase gene variations in Japanese-Americans with a family history of NIDDM
    • Stone, L.M., Kahn, S.E., Deeb, S.S., Fujimoto, W.Y., and Porte, D., Jr. 1994. Glucokinase gene variations in Japanese-Americans with a family history of NIDDM. Diabetes Care. 17:1480-1483.
    • (1994) Diabetes Care , vol.17 , pp. 1480-1483
    • Stone, L.M.1    Kahn, S.E.2    Deeb, S.S.3    Fujimoto, W.Y.4    Porte Jr., D.5
  • 54
    • 0029933511 scopus 로고    scopus 로고
    • A variation at position -30 of the β-cell glucokinase gene promoter is associated with reduced β-cell function in middle-aged Japanese-American men
    • Stone, L.M., Kahn, S.E., Fujimoto, W.Y., Deeb, S.S., and Porte, D., Jr. 1996. A variation at position -30 of the β-cell glucokinase gene promoter is associated with reduced β-cell function in middle-aged Japanese-American men. Diabetes. 45:422-428.
    • (1996) Diabetes , vol.45 , pp. 422-428
    • Stone, L.M.1    Kahn, S.E.2    Fujimoto, W.Y.3    Deeb, S.S.4    Porte Jr., D.5
  • 55
    • 25844513867 scopus 로고    scopus 로고
    • A -30G>A polymorphism of the beta-cell-specific glucokinase promoter associates with hyperglycemia in the general population of whites
    • Rose, C.S., et al. 2005. A -30G>A polymorphism of the beta-cell-specific glucokinase promoter associates with hyperglycemia in the general population of whites. Diabetes. 54:3026-3031.
    • (2005) Diabetes , vol.54 , pp. 3026-3031
    • Rose, C.S.1
  • 56
    • 19944432769 scopus 로고    scopus 로고
    • Genetic regulation of birth weight and fasting glucose by a common polymophism in the islet promoter of the glucokinase gene
    • Weedon, M.N., et al. 2005. Genetic regulation of birth weight and fasting glucose by a common polymophism in the islet promoter of the glucokinase gene. Diabetes. 54:576-581.
    • (2005) Diabetes , vol.54 , pp. 576-581
    • Weedon, M.N.1
  • 58
    • 34248594090 scopus 로고    scopus 로고
    • A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
    • Frayling, T.M., et al. 2007. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science. 316:889-894.
    • (2007) Science , vol.316 , pp. 889-894
    • Frayling, T.M.1
  • 59
    • 38649121127 scopus 로고    scopus 로고
    • Common variants in the GDF5-UQCC region are associated with variation in human height
    • Sanna, S., et al. 2008. Common variants in the GDF5-UQCC region are associated with variation in human height. Nat. Genet. 40:198-203.
    • (2008) Nat. Genet , vol.40 , pp. 198-203
    • Sanna, S.1
  • 60
    • 38649125868 scopus 로고    scopus 로고
    • Newly identified loci that influence lipid concentrations and risk of coronary artery disease
    • Willer, C.J., et al. 2008. Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat. Genet. 40:161-169.
    • (2008) Nat. Genet , vol.40 , pp. 161-169
    • Willer, C.J.1
  • 61
    • 46749089499 scopus 로고    scopus 로고
    • Markov model for rapid haplotyping and genotype imputation in genome wide studies
    • In press
    • Li, Y., Willer, C.J., Ding, J., Scheet, P., and Abecasis, G.R. 2008. Markov model for rapid haplotyping and genotype imputation in genome wide studies. Nat. Genet. In press.
    • (2008) Nat. Genet
    • Li, Y.1    Willer, C.J.2    Ding, J.3    Scheet, P.4    Abecasis, G.R.5
  • 62
    • 46749083684 scopus 로고    scopus 로고
    • . 1999. Definition, diagnosis and classification of diabetes mellitus and its complications. Report of a WHO Consultation. WHO. Geneva, Switzerland. www.diabetes.com.au/pdf/ who_report.pdf.
    • [Anonymous]. 1999. Definition, diagnosis and classification of diabetes mellitus and its complications. Report of a WHO Consultation. WHO. Geneva, Switzerland. www.diabetes.com.au/pdf/ who_report.pdf.
  • 63
    • 0033006003 scopus 로고    scopus 로고
    • Allelic discrimination using fluorogenic probes and the 5′ nuclease assay
    • Livak, K.J. 1999. Allelic discrimination using fluorogenic probes and the 5′ nuclease assay. Genet. Anal. 14:143-149.
    • (1999) Genet. Anal , vol.14 , pp. 143-149
    • Livak, K.J.1
  • 64
    • 33748317890 scopus 로고    scopus 로고
    • In silico method for inferring genotypes in pedigrees
    • Burdick, J.T., Chen, W.M., Abecasis, G.R., and Cheung, V.G. 2006. In silico method for inferring genotypes in pedigrees. Nat. Genet. 38:1002-1004.
    • (2006) Nat. Genet , vol.38 , pp. 1002-1004
    • Burdick, J.T.1    Chen, W.M.2    Abecasis, G.R.3    Cheung, V.G.4
  • 65
    • 34547628858 scopus 로고    scopus 로고
    • Family based association tests for genome wide association scans
    • Chen, W.-M., and Abecasis, G.R. 2007. Family based association tests for genome wide association scans. Am. J. Hum. Genet. 81:913-926.
    • (2007) Am. J. Hum. Genet , vol.81 , pp. 913-926
    • Chen, W.-M.1    Abecasis, G.R.2
  • 66
    • 24144459072 scopus 로고    scopus 로고
    • Approved IFCC recommendations on reporting results for blood glucose (abbreviated)
    • D'Orazio, P., et al. 2005. Approved IFCC recommendations on reporting results for blood glucose (abbreviated). Clin. Chem. 51:1573-1576.
    • (2005) Clin. Chem , vol.51 , pp. 1573-1576
    • D'Orazio, P.1
  • 67
    • 0031442937 scopus 로고    scopus 로고
    • Multipoint oligogenic linkage analysis of quantitative traits
    • Blangero, J., and Almasy, L. 1997. Multipoint oligogenic linkage analysis of quantitative traits. Genet. Epidemiol. 14:959-964.
    • (1997) Genet. Epidemiol , vol.14 , pp. 959-964
    • Blangero, J.1    Almasy, L.2
  • 68
    • 0031966959 scopus 로고    scopus 로고
    • Multipoint quantitative-trait linkage analysis in general pedigrees
    • Almasy, L., and Blangero, J. 1998. Multipoint quantitative-trait linkage analysis in general pedigrees. Am. J. Hum. Genet. 62:1198-1211.
    • (1998) Am. J. Hum. Genet , vol.62 , pp. 1198-1211
    • Almasy, L.1    Blangero, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.