메뉴 건너뛰기




Volumn 52, Issue 12, 2008, Pages 1428-1433

Anthocyanins and their metabolites are weak inhibitors of cytochrome P450 3A4

Author keywords

Anthocyanidin; Anthocyanin; CYP3A4; Cytochrome P450; Flavonoid

Indexed keywords

ANTHOCYANIN; CYP3A4 PROTEIN, HUMAN; CYTOCHROME P450 3A; ENZYME INHIBITOR;

EID: 57549112576     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.200800043     Document Type: Article
Times cited : (24)

References (56)
  • 1
    • 0034855786 scopus 로고    scopus 로고
    • The importance of cytochrome P450 monooxygenase CYP2D6 in palliative medicine
    • Davis, M. P., Homsi, J., The importance of cytochrome P450 monooxygenase CYP2D6 in palliative medicine. Support. Care Cancer 2001, 9, 442-451.
    • (2001) Support. Care Cancer , vol.9 , pp. 442-451
    • Davis, M.P.1    Homsi, J.2
  • 2
    • 0026629691 scopus 로고
    • Evolution of a highly polymorphic human cytochrome. P450 gene cluster: CYP2D6
    • Heim, M. H., Meyer, U. A., Evolution of a highly polymorphic human cytochrome. P450 gene cluster: CYP2D6. Genomics 1992, 14, 49-58.
    • (1992) Genomics , vol.14 , pp. 49-58
    • Heim, M.H.1    Meyer, U.A.2
  • 3
    • 0042664035 scopus 로고    scopus 로고
    • Effect of carbonate anion on cytochrome P450 2D6-mediated metabolism in vitro: The potential role of multiple oxygenating species
    • Hutzler, J. M., Powers, F. J., Wynalda, M. A., Wienkers, L. C., Effect of carbonate anion on cytochrome P450 2D6-mediated metabolism in vitro: The potential role of multiple oxygenating species. Arch. Biochem. Biophys. 2003, 417, 165-175.
    • (2003) Arch. Biochem. Biophys , vol.417 , pp. 165-175
    • Hutzler, J.M.1    Powers, F.J.2    Wynalda, M.A.3    Wienkers, L.C.4
  • 4
    • 1942497956 scopus 로고    scopus 로고
    • Cytochromes P450, drugs, and diseases
    • Guengerich, F. P., Cytochromes P450, drugs, and diseases. Mol. Interv. 2003, 3, 194-204.
    • (2003) Mol. Interv , vol.3 , pp. 194-204
    • Guengerich, F.P.1
  • 5
    • 0028237729 scopus 로고
    • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
    • Shimada, T., Yamazaki, H., Mimura, M., Inui, Y., Guengerich, F. P., Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians. J. Pharmacol. Exp. Ther. 1994, 270, 414-423.
    • (1994) J. Pharmacol. Exp. Ther , vol.270 , pp. 414-423
    • Shimada, T.1    Yamazaki, H.2    Mimura, M.3    Inui, Y.4    Guengerich, F.P.5
  • 6
    • 34247549751 scopus 로고    scopus 로고
    • Radical scavenging and cytochrome P450 3A4 inhibitory activity of bergaptol and geranylcoumarin from grapefruit
    • Girennavar, B., Jayaprakasha, G. K., Jadegoud, Y., Nagana Gowda, G. A., Patil, B. S., Radical scavenging and cytochrome P450 3A4 inhibitory activity of bergaptol and geranylcoumarin from grapefruit. Bioorg. Med. Chem. 2007, 15, 3684-3691.
    • (2007) Bioorg. Med. Chem , vol.15 , pp. 3684-3691
    • Girennavar, B.1    Jayaprakasha, G.K.2    Jadegoud, Y.3    Nagana Gowda, G.A.4    Patil, B.S.5
  • 7
    • 0031748173 scopus 로고    scopus 로고
    • In vitro and in vivo drug interactions involving human CYP3A
    • Thummel, K. E., Wilkinson, G. R., In vitro and in vivo drug interactions involving human CYP3A. Annu. Rev. Pharmacol. Toxicol. 1998, 38, 389-430.
    • (1998) Annu. Rev. Pharmacol. Toxicol , vol.38 , pp. 389-430
    • Thummel, K.E.1    Wilkinson, G.R.2
  • 8
    • 0742289647 scopus 로고    scopus 로고
    • Food-drug interaction: Grapefruit juice augments drug bioavailability - mechanism, extent and relevance
    • Dahan, A., Altman, H., Food-drug interaction: Grapefruit juice augments drug bioavailability - mechanism, extent and relevance. Eur. J. Clin. Nutr. 2004, 58, 1-9.
    • (2004) Eur. J. Clin. Nutr , vol.58 , pp. 1-9
    • Dahan, A.1    Altman, H.2
  • 9
    • 33845988396 scopus 로고    scopus 로고
    • Metabolic drug interactions with newer antipsychotics: A comparative review
    • Spina, E., de Leon, J., Metabolic drug interactions with newer antipsychotics: A comparative review. Basic Clin. Pharmacol. Toxicol. 2007, 100, 4-22.
    • (2007) Basic Clin. Pharmacol. Toxicol , vol.100 , pp. 4-22
    • Spina, E.1    de Leon, J.2
  • 10
    • 0342868292 scopus 로고    scopus 로고
    • Role of furanocoumarins derivatives on grapefruit juice-mediated inhibition of human CYP3A activity
    • Guo, L.-Q., Fukuda, K., Ohta, T., Yamazoe, Y., Role of furanocoumarins derivatives on grapefruit juice-mediated inhibition of human CYP3A activity. Drug Metab. Dispos. 2000, 28, 766-771.
    • (2000) Drug Metab. Dispos , vol.28 , pp. 766-771
    • Guo, L.-Q.1    Fukuda, K.2    Ohta, T.3    Yamazoe, Y.4
  • 11
    • 0034660149 scopus 로고    scopus 로고
    • Inhibition selectivity of grapefruit juice components on human cytochromes P450
    • Tassaneeyakul, W., Guo, L.-Q., Fukuda, K., Ohta, T., Yamazoe, Y., Inhibition selectivity of grapefruit juice components on human cytochromes P450. Arch. Biochem. Biophys. 2000, 378, 356-363.
    • (2000) Arch. Biochem. Biophys , vol.378 , pp. 356-363
    • Tassaneeyakul, W.1    Guo, L.-Q.2    Fukuda, K.3    Ohta, T.4    Yamazoe, Y.5
  • 12
    • 27644546239 scopus 로고    scopus 로고
    • Anthocyans from fruits and vegetables - Does bright colour signal cancer chemopreventive activity?
    • Cooke, D., Steward, W. P., Gescher, A. J., Marczylo, T., Anthocyans from fruits and vegetables - Does bright colour signal cancer chemopreventive activity? Eur. J. Cancer 2005, 41, 1931-1940.
    • (2005) Eur. J. Cancer , vol.41 , pp. 1931-1940
    • Cooke, D.1    Steward, W.P.2    Gescher, A.J.3    Marczylo, T.4
  • 14
    • 33745512076 scopus 로고    scopus 로고
    • Concentrations of anthocyanins in common foods in the United States and estimation of normal consumption
    • Wu, X., Beecher, G. R., Holden, J. M., Haytowitz, D. B., et al., Concentrations of anthocyanins in common foods in the United States and estimation of normal consumption. J. Agric. Food Chem. 2006, 54, 4069-4075.
    • (2006) J. Agric. Food Chem , vol.54 , pp. 4069-4075
    • Wu, X.1    Beecher, G.R.2    Holden, J.M.3    Haytowitz, D.B.4
  • 15
    • 34249848328 scopus 로고    scopus 로고
    • Contents of anthocyanins and ellagitannins in selected foods consumed in Finland
    • Koponen, J. M., Happonen, A. M., Mattila, P. H., Törrönen, A. R., Contents of anthocyanins and ellagitannins in selected foods consumed in Finland. J. Agric. Food Chem. 2007, 55, 1612-1619.
    • (2007) J. Agric. Food Chem , vol.55 , pp. 1612-1619
    • Koponen, J.M.1    Happonen, A.M.2    Mattila, P.H.3    Törrönen, A.R.4
  • 16
    • 0016906546 scopus 로고
    • The flavonoids. A class of semi-essential food components: Their role in human nutrition
    • Kühnau, J., The flavonoids. A class of semi-essential food components: Their role in human nutrition. World Rev. Nutr. Diet 1976, 24, 117-191.
    • (1976) World Rev. Nutr. Diet , vol.24 , pp. 117-191
    • Kühnau, J.1
  • 17
    • 34247898848 scopus 로고    scopus 로고
    • Estimated dietary flavonoid intake and major food sources of U.S. adults
    • Chun, O. K., Chung, S. J., Song, W. O., Estimated dietary flavonoid intake and major food sources of U.S. adults. J. Nutr. 2007, 137, 1244-1252.
    • (2007) J. Nutr , vol.137 , pp. 1244-1252
    • Chun, O.K.1    Chung, S.J.2    Song, W.O.3
  • 18
    • 33746983762 scopus 로고    scopus 로고
    • Inhibitory effects of fruit juices on CYP3A activity
    • Kim, H., Yoon, Y.-J., Shon, J.-H., Cha, I.-J., et al., Inhibitory effects of fruit juices on CYP3A activity. Drug Metab. Dispos. 2006, 34, 521-523.
    • (2006) Drug Metab. Dispos , vol.34 , pp. 521-523
    • Kim, H.1    Yoon, Y.-J.2    Shon, J.-H.3    Cha, I.-J.4
  • 19
    • 0000023835 scopus 로고    scopus 로고
    • Mechanism-based inactivation of human cytochrome P450 3A4 by grapefruit juice and red wine
    • Chan, W. K., Nguyen, L. T., Miller, V. P., Harris, R. Z., Mechanism-based inactivation of human cytochrome P450 3A4 by grapefruit juice and red wine. Life Sci. 1998, 62, 135-142.
    • (1998) Life Sci , vol.62 , pp. 135-142
    • Chan, W.K.1    Nguyen, L.T.2    Miller, V.P.3    Harris, R.Z.4
  • 20
    • 33745853192 scopus 로고    scopus 로고
    • Warfarin-cranberry juice interaction resulting in profound hypoprothrombinemia and bleeding
    • Rindone, J. P., Murphy, T. W., Warfarin-cranberry juice interaction resulting in profound hypoprothrombinemia and bleeding. Am. J. Ther. 2005, 13, 283-284.
    • (2005) Am. J. Ther , vol.13 , pp. 283-284
    • Rindone, J.P.1    Murphy, T.W.2
  • 22
    • 34447515810 scopus 로고    scopus 로고
    • Cranberry and blueberry: Evidence for protective effects against cancer and vascular diseases
    • Neto, C. C., Cranberry and blueberry: Evidence for protective effects against cancer and vascular diseases. Mol. Nutr. Food Res. 2007, 51, 652-664.
    • (2007) Mol. Nutr. Food Res , vol.51 , pp. 652-664
    • Neto, C.C.1
  • 23
    • 0033852366 scopus 로고    scopus 로고
    • Assessing antioxidant and prooxidant activities of phenolic compounds
    • Fukumoto, L. R., Mazza, G., Assessing antioxidant and prooxidant activities of phenolic compounds. J. Agric. Food Chem. 2000, 48, 3597-3604.
    • (2000) J. Agric. Food Chem , vol.48 , pp. 3597-3604
    • Fukumoto, L.R.1    Mazza, G.2
  • 24
    • 0037132563 scopus 로고    scopus 로고
    • Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects
    • Mazza, G., Kay, C. D., Cottrell, T., Holub, B. J., Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects. J. Agric. Food Chem. 2002, 50, 7731-7737.
    • (2002) J. Agric. Food Chem , vol.50 , pp. 7731-7737
    • Mazza, G.1    Kay, C.D.2    Cottrell, T.3    Holub, B.J.4
  • 25
    • 0037438997 scopus 로고    scopus 로고
    • Oxygen radical absorbing capacity of phenolics in blueberries, cranberries, chokeberries, and lingonberries
    • Zheng, W., Wang, S. Y., Oxygen radical absorbing capacity of phenolics in blueberries, cranberries, chokeberries, and lingonberries. J. Agric. Food Chem. 2003, 51, 502-509.
    • (2003) J. Agric. Food Chem , vol.51 , pp. 502-509
    • Zheng, W.1    Wang, S.Y.2
  • 26
    • 29444439023 scopus 로고    scopus 로고
    • Electron spin resonance spectroscopy studies on the free radical scavenging activity of wine anthocyanins and pyranoanthocyanins
    • Garcia-Alonso, M., Rimbach, G., Sasai, M., Nakahara, M., et al., Electron spin resonance spectroscopy studies on the free radical scavenging activity of wine anthocyanins and pyranoanthocyanins. Mol. Nutr. Food Res. 2005, 49, 1112-1119.
    • (2005) Mol. Nutr. Food Res , vol.49 , pp. 1112-1119
    • Garcia-Alonso, M.1    Rimbach, G.2    Sasai, M.3    Nakahara, M.4
  • 27
    • 33749242813 scopus 로고    scopus 로고
    • Superoxide radical- and peroxynitrite-scavenging activity of anthocyanins; structure-activity relationship and their synergism
    • Rahman, M. M., Ichiyanagi, T., Komiyama, T., Hatano, Y., Konishi, T., Superoxide radical- and peroxynitrite-scavenging activity of anthocyanins; structure-activity relationship and their synergism. Free Radic. Res. 2006, 40, 993-1002.
    • (2006) Free Radic. Res , vol.40 , pp. 993-1002
    • Rahman, M.M.1    Ichiyanagi, T.2    Komiyama, T.3    Hatano, Y.4    Konishi, T.5
  • 28
    • 0032986801 scopus 로고    scopus 로고
    • Antioxidant and antiinflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherries
    • Wang, H., Nair, M. G., Strasburg, G. M., Chang, Y.-C., et al., Antioxidant and antiinflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherries. J. Nat. Prod. 1999, 62, 294-296.
    • (1999) J. Nat. Prod , vol.62 , pp. 294-296
    • Wang, H.1    Nair, M.G.2    Strasburg, G.M.3    Chang, Y.-C.4
  • 29
    • 0036265622 scopus 로고    scopus 로고
    • Potential role of dietary flavonoids in reducing microvascular endothelium vulnerability to oxidative and inflammatory insults
    • Youdim, K. A., McDonald, J., Kalt, W., Joseph, J. A., Potential role of dietary flavonoids in reducing microvascular endothelium vulnerability to oxidative and inflammatory insults. J. Nutr. Biochem. 2002, 13, 282-288.
    • (2002) J. Nutr. Biochem , vol.13 , pp. 282-288
    • Youdim, K.A.1    McDonald, J.2    Kalt, W.3    Joseph, J.A.4
  • 30
    • 0037125089 scopus 로고    scopus 로고
    • Effects of anthocyanins and other phenolic compounds on the production of tumor necrosis factor α in LPS/IFN-γ-Activated RAW 264.7 Macrophages
    • Wang, J., Mazza, G., Effects of anthocyanins and other phenolic compounds on the production of tumor necrosis factor α in LPS/IFN-γ-Activated RAW 264.7 Macrophages. J. Agric. Food Chem. 2002, 50, 4183-4189.
    • (2002) J. Agric. Food Chem , vol.50 , pp. 4183-4189
    • Wang, J.1    Mazza, G.2
  • 31
    • 34447519191 scopus 로고    scopus 로고
    • Berry anthocyanins as novel antioxidants in human health and disease prevention
    • Zafra-Stone, S., Yasmin, T., Bagchi, M., Chatterjee, A., et al., Berry anthocyanins as novel antioxidants in human health and disease prevention. Mol. Nutr. Food Res. 2007, 51, 675-683.
    • (2007) Mol. Nutr. Food Res , vol.51 , pp. 675-683
    • Zafra-Stone, S.1    Yasmin, T.2    Bagchi, M.3    Chatterjee, A.4
  • 32
    • 34447505041 scopus 로고    scopus 로고
    • Berry phytochemicals, genomic stability and cancer: Evidence for chemoprotection at several stages in the carcinogenic process
    • Duthie, S. J., Berry phytochemicals, genomic stability and cancer: Evidence for chemoprotection at several stages in the carcinogenic process. Mol. Nutr. Food Res. 2007, 51, 665-674.
    • (2007) Mol. Nutr. Food Res , vol.51 , pp. 665-674
    • Duthie, S.J.1
  • 33
    • 28444463999 scopus 로고    scopus 로고
    • The beneficial effects of fruit polyphenols on brain aging
    • Lau, F. C., Shukitt-Hale, B., Joseph, J. A., The beneficial effects of fruit polyphenols on brain aging. Neurobiol. Aging 2005, 26, S128-S132.
    • (2005) Neurobiol. Aging , vol.26
    • Lau, F.C.1    Shukitt-Hale, B.2    Joseph, J.A.3
  • 34
    • 30544437321 scopus 로고    scopus 로고
    • Sweet and sour cherry phenolics and their protective effects on neuronal cells
    • Kim, D.-O., Heo, H. J., Kim, Y. J., Yang, H. S., Lee, C. Y., Sweet and sour cherry phenolics and their protective effects on neuronal cells. J. Agric. Food Chem. 2005, 53, 9921-9927.
    • (2005) J. Agric. Food Chem , vol.53 , pp. 9921-9927
    • Kim, D.-O.1    Heo, H.J.2    Kim, Y.J.3    Yang, H.S.4    Lee, C.Y.5
  • 35
    • 28444457312 scopus 로고    scopus 로고
    • Neuroprotective effects of the cyanidin-3-O-β-D-glucopyranoside isolated from mulberry fruit against cerebral ischemia
    • Kang, T. H., Hur, J. Y., Kim, H. B., Ryu, J. H., Kim, S. Y., Neuroprotective effects of the cyanidin-3-O-β-D-glucopyranoside isolated from mulberry fruit against cerebral ischemia. Neurosci. Lett. 2006, 391, 168-172.
    • (2006) Neurosci. Lett , vol.391 , pp. 168-172
    • Kang, T.H.1    Hur, J.Y.2    Kim, H.B.3    Ryu, J.H.4    Kim, S.Y.5
  • 36
    • 29844435927 scopus 로고    scopus 로고
    • Blueberry supplemented diet reverses agerelated decline in hippocampal HSP70 neuroprotection
    • Galli, R. L., Bielinski, D. F., Szprengiel, A., Shukitt-Hale, B., Joseph, J. A., Blueberry supplemented diet reverses agerelated decline in hippocampal HSP70 neuroprotection. Neurobiol. Aging 2006, 27, 344-350.
    • (2006) Neurobiol. Aging , vol.27 , pp. 344-350
    • Galli, R.L.1    Bielinski, D.F.2    Szprengiel, A.3    Shukitt-Hale, B.4    Joseph, J.A.5
  • 37
    • 34249717693 scopus 로고    scopus 로고
    • Fruit polyphenols and their effects on neuronal signaling and behavior in senescence
    • Joseph, J. A., Shukitt-Hale, B., Lau, F. C., Fruit polyphenols and their effects on neuronal signaling and behavior in senescence. Ann. NY Acad. Sci. 2007, 1100, 470-485.
    • (2007) Ann. NY Acad. Sci , vol.1100 , pp. 470-485
    • Joseph, J.A.1    Shukitt-Hale, B.2    Lau, F.C.3
  • 38
    • 34249279788 scopus 로고    scopus 로고
    • Beneficial effects of fruit extracts on neuronal function and behavior in a rodent model of accelerated aging
    • Shukitt-Hale, B., Carey, A. N., Jenkins, D., Rabin, B. M., Joseph, J. A., Beneficial effects of fruit extracts on neuronal function and behavior in a rodent model of accelerated aging. Neurobiol. Aging 2007, 28, 1187-1194.
    • (2007) Neurobiol. Aging , vol.28 , pp. 1187-1194
    • Shukitt-Hale, B.1    Carey, A.N.2    Jenkins, D.3    Rabin, B.M.4    Joseph, J.A.5
  • 39
    • 32344444354 scopus 로고    scopus 로고
    • Stability and biotransformation of various dietary anthocyanins in vitro
    • Fleschhut, J., Kratzer, F., Rechkemmer, G., Kulling, S. E., Stability and biotransformation of various dietary anthocyanins in vitro. Eur. J. Nutr. 2006, 45, 7-18.
    • (2006) Eur. J. Nutr , vol.45 , pp. 7-18
    • Fleschhut, J.1    Kratzer, F.2    Rechkemmer, G.3    Kulling, S.E.4
  • 40
    • 0030696487 scopus 로고    scopus 로고
    • Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents - decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins
    • Schmiedlin-Ren, P., Edwards, D. J., Fitzsimmons, M. E., He, K. et al., Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents - decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins. Drug Metab. Dispos. 1997, 25, 1228-1233.
    • (1997) Drug Metab. Dispos , vol.25 , pp. 1228-1233
    • Schmiedlin-Ren, P.1    Edwards, D.J.2    Fitzsimmons, M.E.3    He, K.4
  • 42
    • 57549095427 scopus 로고    scopus 로고
    • Pronsky, Z, Crowe, Sr. J, Young, Y. S. L, Elbe, D, et al, Eds, Food-Medication interaction, Birchrunville, PA, USA 2006
    • Pronsky, Z., Crowe, Sr. J., Young, Y. S. L., Elbe, D., et al. (Eds.), Food-Medication Interactions Handbook, Food-Medication interaction, Birchrunville, PA, USA 2006.
    • Food-Medication Interactions Handbook
  • 43
    • 34548399951 scopus 로고    scopus 로고
    • Protocatechuic acid is the major human metabolite of cyanidin-glucosides
    • Vitaglione, P., Donnarumma, G., Napolitano, A., Galvano, F., et al., Protocatechuic acid is the major human metabolite of cyanidin-glucosides. J. Nutr. 2007, 137, 2043-2048.
    • (2007) J. Nutr , vol.137 , pp. 2043-2048
    • Vitaglione, P.1    Donnarumma, G.2    Napolitano, A.3    Galvano, F.4
  • 44
    • 0033745131 scopus 로고    scopus 로고
    • Polymeric proanthocyanidins are catabolized by human colonic microflora into low-molecular-weight phenolic acids
    • Déprez, S., Brezillon, C., Rabot, S., Philippe, C., et al., Polymeric proanthocyanidins are catabolized by human colonic microflora into low-molecular-weight phenolic acids. J. Nutr. 2000, 130, 2733-2738.
    • (2000) J. Nutr , vol.130 , pp. 2733-2738
    • Déprez, S.1    Brezillon, C.2    Rabot, S.3    Philippe, C.4
  • 45
    • 4143081627 scopus 로고    scopus 로고
    • Supplementation with grape seed polyphenols results in increased urinary excretion of 3-hydroxyphenylpropionic acid, an important metabolite of proanthocyanidins in humans
    • Ward, N. C., Croft, K. D., Puddey, I. B., Hodgson, J. M., Supplementation with grape seed polyphenols results in increased urinary excretion of 3-hydroxyphenylpropionic acid, an important metabolite of proanthocyanidins in humans. J. Agric. Food Chem. 2004, 52, 5545-5549.
    • (2004) J. Agric. Food Chem , vol.52 , pp. 5545-5549
    • Ward, N.C.1    Croft, K.D.2    Puddey, I.B.3    Hodgson, J.M.4
  • 47
    • 0034927092 scopus 로고    scopus 로고
    • Red wine-cisapride interaction: Comparison with grapefruit juice
    • Offman, E. M., Freeman, D. J., Dresser, G. K., Munoz, C., et al., Red wine-cisapride interaction: Comparison with grapefruit juice. Clin. Pharmacol. Ther. 2001, 70, 17-23.
    • (2001) Clin. Pharmacol. Ther , vol.70 , pp. 17-23
    • Offman, E.M.1    Freeman, D.J.2    Dresser, G.K.3    Munoz, C.4
  • 48
    • 0742287122 scopus 로고    scopus 로고
    • Drug-drug interactions evaluated by a highly active reconstituted native human cytochrome P4503A4 and human NADPH-cytochrome P450 reductase system
    • Haehner, T., Refaie, M. O., Müller-Enoch, D., Drug-drug interactions evaluated by a highly active reconstituted native human cytochrome P4503A4 and human NADPH-cytochrome P450 reductase system. Arzneimittelforschung 2004, 54, 78-83.
    • (2004) Arzneimittelforschung , vol.54 , pp. 78-83
    • Haehner, T.1    Refaie, M.O.2    Müller-Enoch, D.3
  • 49
    • 0035828180 scopus 로고    scopus 로고
    • Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450
    • Muto, S., Fujita, K., Yamazaki, Y., Kamataki, T., Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450. Mutat. Res. 2001, 479, 197-206.
    • (2001) Mutat. Res , vol.479 , pp. 197-206
    • Muto, S.1    Fujita, K.2    Yamazaki, Y.3    Kamataki, T.4
  • 50
    • 3843064658 scopus 로고    scopus 로고
    • The inhibitory effects of herbal components on CYP2C9 and CYP3A4 catalytic activities in human liver microsomes
    • He, N., Edeki, T., The inhibitory effects of herbal components on CYP2C9 and CYP3A4 catalytic activities in human liver microsomes. Am. J. Ther. 2004, 11, 206-212.
    • (2004) Am. J. Ther , vol.11 , pp. 206-212
    • He, N.1    Edeki, T.2
  • 51
    • 34247646955 scopus 로고    scopus 로고
    • Inhibition of human recombinant cytochrome P450s by curcumin and curcumin decomposition products
    • Appiah-Opong, R., Commandeur, J. N. M., van Vugt-Lussenburg, B., Vermeulen, N. P. E., Inhibition of human recombinant cytochrome P450s by curcumin and curcumin decomposition products. Toxicology 2007, 235, 83-91.
    • (2007) Toxicology , vol.235 , pp. 83-91
    • Appiah-Opong, R.1    Commandeur, J.N.M.2    van Vugt-Lussenburg, B.3    Vermeulen, N.P.E.4
  • 52
    • 0035976379 scopus 로고    scopus 로고
    • Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components
    • Piver, B., Berthou, F., Dreano, Y., Lucas, D., Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components. Toxicol. Lett. 2001, 125, 83-91.
    • (2001) Toxicol. Lett , vol.125 , pp. 83-91
    • Piver, B.1    Berthou, F.2    Dreano, Y.3    Lucas, D.4
  • 55
    • 0041802941 scopus 로고    scopus 로고
    • Anthocyanin glycosides from berry fruit are absorbed and excreted unmetabolized by both humans and rats
    • McGhie, T. K., Ainge, G. D., Barnett, L. E., Cooney, J. M., Jensen, D. J., Anthocyanin glycosides from berry fruit are absorbed and excreted unmetabolized by both humans and rats. J. Agric. Food Chem. 2003, 51, 4539-4548.
    • (2003) J. Agric. Food Chem , vol.51 , pp. 4539-4548
    • McGhie, T.K.1    Ainge, G.D.2    Barnett, L.E.3    Cooney, J.M.4    Jensen, D.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.