Identification of epoxybergamottin as a CYP3A4 inhibitor in grapefruit peel

European Journal of Clinical Pharmacology

Volumn 58, Issue 10, 2003, Pages 663-668

  Wangensteen, H ^a   Molden, E ^a   Christensen, H ^a   Malterud, K E ^a  

^a UNIVERSITY OF OSLO   (Norway)

Author keywords

Epoxybergamottin; Furanocoumarins; Grapefruit peel

Indexed keywords

3,5,6,7,8,3',4' HEPTAMETHOXYFLAVONE; AURAPTENE; COUMARIN DERIVATIVE; CYTOCHROME P450 3A4; CYTOCHROME P450 INHIBITOR; DILTIAZEM; EPOXYAURAPTEN; EPOXYBERGAMOTTIN; ETHER; LIMONENE; MERANZIN; SIBIRICIN; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEMETHYLATION; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG PURIFICATION; ENZYME ACTIVITY; ENZYME INHIBITION; EPITHELIUM CELL; FRACTIONATION; GENETIC TRANSFECTION; GRAPEFRUIT; GRAPEFRUIT JUICE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC 50; LIVER CELL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; SEPARATION TECHNIQUE; STRUCTURE ACTIVITY RELATION; THIN LAYER CHROMATOGRAPHY;

EID: 0347296118     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-002-0537-3     Document Type: Article

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