Potentiated and preferential effects of combined paraquat and maneb on nigrostriatal dopamine systems: Environmental risk factors for Parkinson’s disease?

Brain Research

Volumn 873, Issue 2, 2000, Pages 225-234

  Thiruchelvam, M ^a   Brockel, B J ^a   Richfield, E K ^a   Baggs, R B ^a   Cory Slechta, D A ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Dopamine; Immunohistochemistry; Locomotor activity; Parkinson s Disease; Striatum; Substantia nigra; Tyrosine hydroxylase

Indexed keywords

AGRICULTURAL CHEMICAL; MANEB; PARAQUAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; ENVIRONMENTAL EXPOSURE; MALE; MOUSE; NEUROTOXICITY; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PARKINSON DISEASE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RISK FACTOR; UNITED STATES;

ANIMALS; BODY WEIGHT; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENVIRONMENTAL EXPOSURE; LUNG; MALE; MANEB; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; NEOSTRIATUM; NEURAL PATHWAYS; NEURONS; PARAQUAT; PARKINSONIAN DISORDERS; RISK FACTORS; SUBSTANTIA NIGRA; TIME FACTORS; TYROSINE 3-MONOOXYGENASE;

EID: 0034637267     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)02496-3     Document Type: Article

References (60)

1. Ansah T.A., Wade L.H., Shockley D.C. Effects of calcium channel entry blockers on cocaine and amphetamine-induced motor activities and toxicities. Life Sciences. 53:1993;1947-1956.
2. Bagetta G., Corasaniti M.I., Iannone M., Nistico G., Stephenson J.D. Production of limbic motor seizures and brain damage by systemic and intracerebral injections of paraquat in rats. Pharmacol. Toxicol. 71:1992;443-448.
3. Barden H., Levine S. Histochemical observations on rodent brain melanin. Brain Res. Bull. 10:1983;847-851.
4. Berg G.L. Farm Chemicals Handbook. 1977;161-162 Meister, Willoughby, OH.
5. Berman S.B., Hastings T.G. Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: implications for Parkinson's disease. J. Neurochem. 73:1999;1127-1137.
6. Brocker E.R., Schlatter C. Influence of some cations on the intestinal absorption of maneb. J. Agric. Food Chem. 27:1979;3303-3306.
7. Bus J.S., Cagen S.Z., Olgaard M., Gibson J.E. A mechanism of paraquat toxicity in mice and rats. Toxicol. Appl. Pharmacol. 35:1976;501-513.
8. Calo M., Iannone M., Passafaro M., Nistico G. Selective vulnerability of hippocampal CA3 neurones after microinfusion of paraquat into the rat substantia nigra or into the ventral tegmental area. J. Comparative Pathol. 103:1990;73-78.
9. Corasaniti M.T., Nistico G. Determination of paraquat in rat brain by high-performance liquid chromatography. J. Chromatogr. 643:1993;419-425.
10. Crofton K.M., Boncek V.M., MacPhail R.C. Evidence for monoaminergic involvement in triadimefon-induced hyperactivity. Psychopharmacology. 97:1989;326-330.
11. D'Amato R.J., Alexander G.M., Schwartzman R.J., Kitt C.A., Price D.L., Snyder S.H. Evidence for neuromelanin involvement in MPTP-induced neurotoxicity. Nature. 327:1987;324-326.
12. Dey M.S., Breeze R.G., Hayton W.L., Karara A.H., Krieger R.I. Paraquat pharmacokinetics using a subcutaneous toxic low dose in the rat. Fundam. Appl. Toxicol. 14:1990;208-216.
13. Drew R., Gram T.E. Vehicle alteration of paraquat lethality in mice. Toxicol. Appl. Pharmacol. 48:1979;479-487.
14. Ferraz H.B., Bertolucci P.H.F., Pereira J.S., Lima J.G.C., Andrade L.A.F. Chronic exposure to the fungicide maneb may produce symptoms and signs of CNS mangenese intoxication. Neurology. 38:1988;550-553.
15. Fleming L., Mann J.B., Bean J., Briggle T., Sanchez-Ramos J.R. Parkinson's disease and brain levels of organochlorine pesticides. Ann. Neurol. 36:1994;100-103.
16. Gorell J.M., Johnson C.C., Rybicki B.A., Peterson E.L., Richardson R.J. The risk of Parkinson's disease with exposure to pesticides, farming, well water, and rural living. Neurology. 50:1998;1346-1350.
17. Hertzman C., Wiens M., Bowering D., Snow B., Calne D. Parkinson's disease: A case control study of occupational and environmental risk factors. Am. J. Indust. Med. 17:1990;349-355.
18. Hirsch E., Graybiel A.M., Agid Y.A. Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease. Nature. 334:1988;345-348.
19. Hirsch E.C., Graybiel A.M., Agid Y. Selective vulnerability of pigmented dopaminergic neurons in Parkinson's disease. Acta Neurol. Scand. 126:1989;19-22.
20. Hubble J.P., Cao B.S., Hassanein R.E.S., Neuberger J.S., Koller W.C. Risk factors for Parkinson's disease. Neurology. 43:1993;1693-1697.
21. Ikaiddi M.U., Akunne H.C., Soliman K.F.A. Behavioral and neurochemical effects of acute and repeated administration of triadimefon in the male rat. NeuroToxicology. 18:1997;771-780.
22. Imaizumi Y. Geographical variations in mortality from Parkinson's disease in Japan, 1977-1985. Acta Neurol. Scand. 91:1995;311-316.
23. Jordan L.W., Neal R.A. Examination of the in vivo metabolism of maneb and zineb to ethylenethiourea (ETU) in mice. Bull. Environ. Contam. Toxicol. 22:1979;271-277.
24. Kogan F.J., Nichols W.K., Gibb J.W. Influence of methamphetamine on nigral and striatal tyrosine hydroxylase activity and on striatal dopamine levels. Eur. J. Pharmacol. 36:1976;363-371.
25. Langston J.W., Ballard P.A., Tetrud J.W., Irwin I. Chronic parkinsonism in humans due to a product of meperidine-analog synthesis. Science. 219:1983;979-980.
26. Lanska D.J. The geographic distribution of Parkinson's disease mortality in the United States. J. Neurol. Sci. 150:1997;63-70.
27. 14C]diquat in frogs and mice: accumulation in neuromelanin. Neurosci. Lett. 93:1988;1-6.
28. Liou H.H., Chen R.C., Tsai Y.F., Chen W.P., Chang Y.C., Tsai M.C. Effects of paraquat on the substantia nigra of the Wistar rats: Neurochemical, histological, and behavioral studies. Toxicol. Appl. Pharmacol. 137:1996;34-41.
29. Liou H.H., Tsai M.C., Chen C.J., Jeng J.S., Chang Y.S., Chen S.Y., Chen R.C. Environmental risk factors and Parkinson's disease: A case control study in Taiwan. Neurology. 48:1997;1583-1588.
30. Markey S.P., Weisz A., Bacon J.P. Reduced paraquat does not exhibit MPTP-like neurotoxicity. J. Anal. Toxicol. 10:1986;257.
31. McGeer P.L., Itagaki S., Akiyama H., McGeer E.G. Rate of cell death in Parkinsonism indicates active neuropathological process. Ann. Neurol. 24:1988;574-576.
32. Meco G., Bonifati V., Vanacore N., Fabrizio E. Parkinsonism after chronic exposure to the fungicide maneb (manganese ethylene-bis-dithiocarbamate. Scand. J. Work Environ. Health. 20:1994;301-305.
33. Miller D.B., Reinhard J.F., Daniels A.J., O'Callaghan J.P. Diethyldithiocarbamate potentiates the neurotoxicity of in vivo 1-methyl-4 phenyl-1,2,3,6-tetrahydropyridine and of in vitro 1-methyl-4-phenylpyridinium. J. Neurochem. 57:1991;541-549.
34. Morato G.S., Lemos T., Takahashi R.N. Acute exposure to maneb alters some behavioral functions in the mouse. Neurotoxicol. Teratol. 11:1989;421-425.
35. Newsome W.H. Residues of four ethylenebis(dithiocarbamates) and their decomposition products on field-sprayed tomatoes. J. Agric. Food Chem. 24:1976;999-1001.
36. Newsome W.H. Residues of mancozeb, 2-imidazoline, and theyleneurea in tomato and potato crops after field treatment with mancozeb. J. Agric. Food Chem. 27:1979;1188-1190.
37. Patsakos P.G., Liapis K., Miliadis G.E., Zafiriou K. Mancozeb residues of field sprayed apricots. Bull. Environ. Contam. Toxicol. 48:1992;756-761.
38. Perkins A.N., Eckerman D.A., MacPhail R.C. Discriminative stimulus properties of triadimefon: Comparisons with methylphenidate. Pharmacol. Biochem. Behav. 40:1991;757-761.
39. Perry T.L., Yong V.W., Wall R.A., Jones K. Paraquat and two endogenous analogues of the neurotoxic substance N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine do not damage dopaminergic nigrostriatal neurons in the mouse. Neurosci. Lett. 69:1986;285-289.
40. Rosenzewig-Lipson S., Thomas S., Barrett J.E. Attenuation of the locomotor activating effects of D-amphetamine, cocaine and scopolamine by potassium channel modulators. Prog. Neuropsychopharmacol. Biol. Psychiatry. 21:1997;853-872.
41. Sahakian B.J., Robbins T.W., Morgan M.J., Iversen S.D. The effects of psychomotor stimulants on stereotypy and locomotor activity in socially deprived and control rats. Brain Res. 84:1975;195-205.
42. Sanchez-Ramos J., Facca A., Basit A., Song S. Toxicity of dieldrin for dopaminergic neurons in mesencephalic cultures. Exp. Neurol. 150:1998;263-271.
43. Semchuk K.M., Love E.J., Lee R.G. Parkinson's disease and exposure to agricultural work and pesticide chemicals. Neurology. 42:1992;1328-1335.
44. Sharp C.W., Ottolenghi A., Posner H.S. Correlation of paraquat toxicity with tissue concentrations and weight loss of the rat. Toxicol. Appl. Pharmacol. 22:1972;241-251.
45. Shimada H., Hirai K.-I., Simamura E., Pan J. Mitochondrial NADH-quinone oxidoreductase of the outer membrane is responsible for paraquat cytotoxicity in rat livers. Arch. Biochem. Biophys. 351:1998;75-81.
46. Soleo L., Defazio G., Scarselli R., Zefferino R., Livrea P., Foa V. Toxicity of fungicides containing ethylene-bis-dithiocarbamate in serumless dissociated mesencephalic-striatal primary co-culture. Arch. Toxicol. 70:1996;678-682.
47. Sonsalla P.K., Jochnowitz N.D., Zeevalk G.D., Oostveen J.A., Hall E.D. Treatment of mice with methamphetamine produces cell loss in the substantia nigra. Brain Res. 738:1996;172-175.
48. Sonsalla P.K., Nicklas W.J., Heikkila R.E. Role for excitatory amino acids in methamphetamine-induced nigrostriatal dopaminergic toxicity. Science. 243:1989;398-400.
49. Svenson L.W., Platt G.H., Woodhead S.E. Geographic variations in the prevalence rates of Parkinson's Disease in Alberta. Can. J. Neurol. Sci. 20:1993;307-311.
50. Takahashi R.N., Rogerio R., Zanin M. Maneb enhances MPTP neurotoxicity in mice. Res. Commun. Chem. Pathol. Pharmacol. 66:1989;167-170.
51. Tanner C.M., Chen B., Wang W.Z., Peng M.L., Liu Z.L., Liang X.L., Kao L.C., Gilley D.W., Schoenberg B.S. Environmental factors in the etiology of Parkinson's disease. Can. J. Neurol. Sci. 14:1987;419-423.
52. Vaccari A., Saba P., Mocci I., Ruiu S. Dithiocarbamate pesticides affect glutamate transport in brain synaptic vesicles. J. Pharmacol. Exp. Therapeut. 288:1999;1-5.
53. Walker Q.D., Lewis M.H., Crofton K.M., Mailman R.B. Triadimefon, a triazole fungicide, induces stereotyped behavior and alters monoamine metabolism in rats. Toxicol. Appl. Pharmacol. 102:1990;474-485.
54. Walker Q.D., Mailman R.C. Triadimefon and triadimenol: Effects on monoamine uptake and release. Toxicol. Appl. Pharmacol. 139:1996;227-233.
55. Walters T.L., Irwin I., Delfani K., Langston W.J., Janson A.M. Diethyldithiocarbamate causes nigral cell loss and dopamine depletion with nontoxic doses of MPTP. Exp. Neurol. 156:1999;62-70.
56. Whitton P.S., Maione S., Biggs C.S., Fowler L.J. N-methyl-D-aspartate receptors modulate extracellular dopamine concentration and metabolism in rat hippocampus and striatum in vivo. Brain Res. 635:1994;312-316.
57. Widdowson P.S., Farnworth M.J., Simpson M.G., Lock E.A. Influence on age on the passage of paraquat through the blood-brain barrier in rats: A distribution and pathological examination. Hum. Exper. Toxicol. 15:1996;231-236.
58. Yamamoto H.A. Protection against paraquat-induced toxicity with sulfite or thiosulfate in mice. Toxicology. 79:1993;37-43.
59. Yang W., Sun A.Y. Paraquat induced free radical reaction in mouse brain microsomes. Neurochem. Res. 23:1998;47-53.
60. Yoshimura Y., Watanabe Y., Shibuya T. Inhibitory effects of calcium channel antagonists on motor dysfunction induced by intracerebroventricular administration of paraquat. Pharmacol. Toxicol. 72:1993;229-235.