Nitric oxide synthase and neuronal vulnerability in Parkinson's disease

Neuroscience

Volumn 72, Issue 2, 1996, Pages 355-363

  Hunot, S ^a   Boissiere F ^a   Faucheux, B ^a   Brugg, B ^a   Mouatt Prigent, A ^a   Agid, Y ^a   Hirsch, E C ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

dopamine; human; mesencephalon; NADPH diaphorase; neurodegeneration; nitric oxide

Indexed keywords

NITRIC OXIDE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; FEMALE; GLIA CELL; HISTOCHEMISTRY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PARKINSON DISEASE; PRIORITY JOURNAL; SUBSTANTIA NIGRA;

EID: 0343844458     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-4522(95)00578-1     Document Type: Article

References (60)

1. Agid Y. (1991) Parkinson's disease: pathophysiology. Lancet 337, 1321-1324.
2. Agid Y., Ruberg M., Javoy-Agid F., Hirsch E., Raisman-Vozari R., Vyas S., Faucheux B., Michel P., Kastner A., Blanchard V., Damier P., Villares J. and Zhang P. (1993) Are dopaminergic neurons selectively vulnerable to Parkinson's disease? Advances in Neurology (eds Narabayashi H., Nagatsu T., Yanagisawa N. and Mizuno Y.), Vol. 60, pp. 148-164. Raven Press, New York.
3. Banati R. B., Gehrmann J., Schubert P. and Kreutzberg G. W. (1993) Cytotoxicity of microglia. Glia 7, 111-118.
4. Beckman J. S., Beckman T. W., Chen J., Marshall P. A. and Freeman B. A. (1990) Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and Superoxide. Proc. natn. Acad. Sci. U.S.A. 87, 1620-1624.
5. Bö L., Dawson T. M., Wesselingh S., Mörk S., Choi S., Kong P. A., Hanley D. and Trapp B. D. (1994) Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains. Ann. Neurol. 36, 778-786.
6. Boka G., Anglade P., Wallach D., Javoy-Agid F., Agid Y. and Hirsch E. C. (1994) Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease. Neurosci. Lett. 172, 151-154.
7. Bolaňos J. P., Peuchen S., Heales S. J. R., Land J. M. and Clark J. B. (1994) Nitric oxide-mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes. J. Neurochem. 63, 910-916.
8. -) induces apoptosis in rat cortical cultures. Soc. Neurosci. Abstr. 20, 278.8.
9. Bredt D. S., Glatt C. E., Hwang P. M., Fotuhi M., Dawson T. M. and Snyder S. H. (1991) Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase. Neuron 7, 615-624.
10. Bredt D. S., Hwang P. M., Glatt C. E., Lowenstein C., Reed R. R. and Snyder S. H. (1991) Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase. Nature 351, 714-718.
11. Bredt D. S., Hwang P. M. and Snyder S. H. (1990) Localization of nitric oxide synthase indicating a neuronal role for nitric oxide. Nature 347, 768-770.
12. Bredt D. S. and Snyder S. H. (1990) Isolation of nitric oxide synthase: a calmodulin-requiring enzyme. Proc. natn. Acad. Sci. U.S.A. 87, 682-685.
13. Chao C. C., Hu S., Molitor T. W., Shaskan E. G. and Peterson P. K. (1992) Activated microglia mediate neuronal cell injury via a nitric oxide mechanism J. Immun. 149, 2736-2741.
14. Dawson T. M., Dawson V. L. and Snyder S. H. (1992) A novel neuronal messenger molecule in brains: the free radical, nitric oxide. Ann. Neurol. 32, 297-311.
15. Dawson V. L., Brahmbhatt H. P., Mong J. A. and Dawson T. M. (1994) Expression of inducible nitric oxide synthase causes delayed neurotoxicity in primary mixed neuronal-glial cortical cultures. Neuropharmacology 33, 1425-1430.
16. Dawson V. L., Dawson T. M., London E. D., Bredt D. S. and Snyder S. H. (1991) Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures. Proc. natn. Acad. Sci. U.S.A. 88, 6368-6371.
17. Demerlé-Pallardy C., Lonchampt M.-O., Chabrier P.-E. and Braquet P. (1993) Nitric oxide synthase induction in glial cells: effect on neuronal survival. Life Sci. 52, 1883-1890.
18. Dexter D. T., Carayaon A., Vidailhet M., Ruberg M., Agid F., Agid Y., Lees A. J., Wells F. R., Jenner P. and Marsden C. D. (1990) Decreased ferritin levels in brain in Parkinson's disease. J. Neurochem. 55, 16-20.
19. Dexter D. T., Carter C. J., Wells F. R., Javoy-Agid F., Agid Y., Lees A., Jenner P. and Marsden C. D. (1989) Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease. J. Neurochem. 52, 381-389.
20. Dexter D. T., Wells F. R., Lees A. J., Agid F., Agid Y., Jenner P. and Marsden C. D. (1989) Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease. J. Neurochem. 52, 1830-1836.
21. Earle K. M. (1968) Studies on Parkinson's disease including X-ray fluorescent spectroscopy of formalin fixed brain tissue. J. Neuropath, exp. Neurol. 27, 1-14.
22. Egberongbe Y. I., Gentleman S. M., Falkai P., Bogerts B., Polak J. M. and Roberts G. W. (1994) The distribution of nitric oxide synthase immunoreactivity in the human brain. Neuroscience 59, 561-578.
23. Endoh M., Maiese K., Pulsinelli W. A. and Wagner J. A. (1993) Reactive astrocytes express NADPH diaphorase in vivo after transient ischemia. Neurosci. Lett. 54, 125-128.
24. Endoh M., Maiese K. and Wagner J. A. (1993) Reactive astrocytes express inducible nitric oxide synthase after ischemia. Soc. Neurosci. Abstr. 19, 1660.
25. Faucheux B. A., Nillesse N., Damier P., Spik G., Mouatt-Prigent A., Pierce A., Leveugle B., Kubis N., Hauw J. J., Agid Y. and Hirsch E. C. (1995). Expression of lactoferrin receptors is increased in the mesencephalon of patients with Parkinson's disease. Proc. natn. Acad. Sci. U.S.A. 92, 9603-9607.
26. Ferrante R. J., Kowall N. W., Beal M. F., Richardson E. P., Bird E. P. and Martin J. B. (1985) Selective sparing of a class of striatal neurons in Huntington's disease. Science 230, 561-563.
27. Good P. F., Olanow C. W. and Perl D. P. (1992) Neuromelanin-containing neurons of the substantia nigra accumulate iron and aluminium in Parkinson's disease: a LAMMA study. Brain Res. 593, 343-346.
28. Hirsch E., Graybiel A. M. and Agid Y. (1988) Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease. Nature 334, 345-348.
29. Hirsch E. C. (1993) Does oxidative stress participate in nerve cell death in Parkinson's disease? Eur. Neurol. 33, 52-59
30. Hirsch E. C., Brandel J. P., Galle P., Javoy-Agid F. and Agid Y. (1991) Iron and aluminium increase in the substantia nigra of patients with Parkinson's disease. An X-ray microanalysis. J. Neurochem. 56, 446-451.
31. Hope B. T., Michael G. J., Knigge K. M. and Vincent S. R. (1991) Neuronal NADPH diaphorase is a nitric oxide synthase. Proc. natn. Acad. Sci. U.S.A. 88, 2811-2814.
32. Hsu S. M., Raine L. and Fanger H. (1981) Use of avidin-biotin-peroxidase complex (ABC) in immuno-peroxidase techniques: a comparison between ABC and unlabelled antibody (PAP) procedures. J. Histochem. Cytochem. 29, 577-580.
33. Jellinger K., Kienzl E., Rumpelmair G., Riederer P., Stachelberger H., Ben-Shachar D. and Youdim M.B.H. (1992) Iron-melanin complex in substantia nigra of Parkinsonian brains: An X-ray microanalysis. J. Neurochem. 59, 1168-1171.
34. Jun C-D., Choi B.-M., H.-Ryu, Um J.-Y., Kwak H.-J., Lee B.-S., Paik S.-G., Kim H.-M. and Chung H.-T. (1994) Synergistic cooperation between phorbol ester and IFN-y for induction of nitric oxide synthesis in murine peritoneal macrophages. J. Immun. 153, 3684-3690.
35. Kopmels B., Wollman E. E., Guastavino J. M., Delhaye-Bouchaud N., Fradelizi D. and Mariani J. (1990) Interleukine-1 hyperproduction by in vitro activated peripheral macrophages from cerebellar mutant mice. J. Neurochem. 55, 1980-1985.
36. Kowall N. W. and Beal M. F. (1988) Cortical somatostatin, neuropeptide Y and NADPH diaphorase neurons: normal anatomy and alterations in Alzheimer's disease. Ann. Neurol. 23, 105-114.
37. Lamas S., Marsden P. A., Li G. K., Tempst P. and Michel T. (1992) Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform. Proc. natn. Acad. Sci. U.S.A. 89, 6348-6352.
38. Levine W., Giuditta A., Englard S. and Stecker H. J. (1960) Brain diaphorases. J. Neurochem. 6, 28-36.
39. Mallat M., Chamak B. and Théry C. (1991) Les macrophages cérébraux: rôle dans les remaniements morphologiques et la dégénérescence des neurones. Médecine/sciences 7, 768-774.
40. Matsumoto T., Nakane M., Pollock J.S., Kuk J. E. and Forstermann U. (1993) A correlation between soluble brain nitric oxide synthase and NADPH-diaphorase activity is only seen after exposure of the tissue to fixative. Neurosci. Lett. 155, 61-64.
41. McGeer P. L., Itagaki S., Boyes B. E. and McGeer E. G. (1988) Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology 38, 1285-1291.
42. ++ -calmodulin-independent NO-synthase. Biochem. biophys. Res. Commun. 191, 327-332.
43. Moncada S., Palmer R. M. J. and Higgs E. A. (1991) Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmac. Rev. 43, 109-141.
44. Pantopoulos K. and Hentze M. W. (1995) Nitric oxide signaling to iron-regulatory protein: direct control of ferritin mRNA translation and transferrin receptor mRNA stability in transfected fibroblasts. Proc. natn. Acad. Sci. U.S.A. 92, 1267-1271.
45. Park S. K., Grzybicki D., Lin H. L. and Murphy S. (1994) Modulation of inducible nitric oxide synthase expression in astroglial cells. Neuropharmacology 33, 1419-1423.
46. Radi R., Beckman J. S., Bush K. M. and Freeman B. A. (1991) Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of Superoxide and nitric oxide. J. biol. Chem. 266, 4244-4250.
47. Reif D. W. and Simmons R. D. (1990) Nitric oxide mediates iron release from ferritin. Archs Biochem. Biophys. 283, 537-541.
48. Richard Lyons C., Orloff G. J. and Cunningham J. M. (1992) Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophages cell line. J. biol. Chem. 267, 6370-6374.
49. Riederer P., Sofic E., Rausch W.-D., Schmidt B., Reynolds G. P., Jellinger K. and Youdim M. B. H. (1989) Transition metals, ferritin, glutathione, and ascorbic acid in Parkinsonian brains. J. Neurochem. 52, 515-520.
50. Schapira A. H. V., Cooper J. M., Dexter D., Clark J. B., Jenner P. and Marsden C. D. (1990) Mitochondrial complex I deficiency in Parkinson's disease. J. Neurochem. 54, 823-827.
51. Simmons M. L. and Murphy S. (1992) Induction of nitric oxide synthase in glial cells. J. Neurochem. 59, 897-905.
52. Sims K. L., Kauffman F. C., Johnson E. C. and Pickel V. M. (1974) Cytochemical localization of brain nicotinamide adenine dinucleotide phosphate (oxidized)-dependent dehydrogenases. Qualitative and quantitative distributions. J. Histochem. Cytochem. 22, 7-19.
53. Stuehr D. J. and Nathan C. F. (1989) A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells. J. exp. Med. 169, 1543-1555.
54. Vigne P., Damais C. and Frelin C. (1993) IL1 and TNFa induce cGMP formation in C6 astrocytoma cells via the nitridergic pathway. Brain Res. 606, 332-336.
55. Vincent S. R. and Kimura H. (1992) Histochemical mapping of nitric oxide synthase in the rat brain. Neuroscience 46, 755-784.
56. Wallace M. N. and Bisland S. K. (1994) NADPH-diaphorase activity in activated astrocytes represents inducible nitric oxide synthase. Neuroscience 59, 905-919.
57. Weibel E. R. (1979) Stereological Methods. Vol. 1, Chap. 4, pp. 101-161. Academic Press, London.
58. Wink D. A., Hanbauer I., Krishna M. C., DeGraff W., Gamson J. and Mitchell J. B. (1993) Nitric oxide protects against cellular damage and cytotoxicity from reactive oxygen species. Proc. natn. Acad. Sci. U.S.A. 90, 9813-9817.
59. Xie Q.-W., Cho H. J., Calaycay J., Mumford R. A., Swiderek K. M., Lee T. D., Ding A., Troso T. and Nathan C. (1992) Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science 256, 225-228.
60. Youdim M. B. H., Ben-Shachar D., Eshel G., Finberg J. P. M. and Riederer P. (1993) The neurotoxicity of iron and nitric oxide. Relevance to the etiology of Parkinson's disease. Advances in Neurology (eds Narabayashi M., Nagatsu T., Yanagisame N. and Mizuno Y.), Vol. 60, pp. 259-266. Raven Press, New York.