-
1
-
-
0013907774
-
Werner's syndrome a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process
-
Epstein C.J., Martin G.M., Schultz A.L., and Motulsky A.G. Werner's syndrome a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process. Med. (Baltimore) 45 (1966) 177-221
-
(1966)
Med. (Baltimore)
, vol.45
, pp. 177-221
-
-
Epstein, C.J.1
Martin, G.M.2
Schultz, A.L.3
Motulsky, A.G.4
-
2
-
-
15844409553
-
Positional cloning of the Werner's syndrome gene
-
Yu C.E., Oshima J., Fu Y.H., Wijsman E.M., Hisama F., Alisch R., Matthews S., Nakura J., Miki T., Ouais S., Martin G.M., Mulligan J., and Schellenberg G.D. Positional cloning of the Werner's syndrome gene. Science 272 (1996) 258-262
-
(1996)
Science
, vol.272
, pp. 258-262
-
-
Yu, C.E.1
Oshima, J.2
Fu, Y.H.3
Wijsman, E.M.4
Hisama, F.5
Alisch, R.6
Matthews, S.7
Nakura, J.8
Miki, T.9
Ouais, S.10
Martin, G.M.11
Mulligan, J.12
Schellenberg, G.D.13
-
3
-
-
0028785586
-
The Bloom's syndrome gene product is homologous to RecQ helicases
-
Ellis N.A., Groden J., Ye T.-Z., Straughen J., Lennon D.J., Ciocci S., Proytcheva M., and German J. The Bloom's syndrome gene product is homologous to RecQ helicases. Cell 83 (1995) 655-666
-
(1995)
Cell
, vol.83
, pp. 655-666
-
-
Ellis, N.A.1
Groden, J.2
Ye, T.-Z.3
Straughen, J.4
Lennon, D.J.5
Ciocci, S.6
Proytcheva, M.7
German, J.8
-
4
-
-
0032939991
-
Mutations in RecQL4 cause a subset of cases of Rothmund-Thomson syndrome
-
Kitao S., Shimamoto A., Goto M., Miller R.W., Smithson W.A., Lindor N.M., and Furuichi Y. Mutations in RecQL4 cause a subset of cases of Rothmund-Thomson syndrome. Nat. Genet. 22 (1999) 82-84
-
(1999)
Nat. Genet.
, vol.22
, pp. 82-84
-
-
Kitao, S.1
Shimamoto, A.2
Goto, M.3
Miller, R.W.4
Smithson, W.A.5
Lindor, N.M.6
Furuichi, Y.7
-
5
-
-
0035062128
-
DNA helicase deficiencies associated with cancer predisposition and premature aging disorder
-
Mohaghegh P., and Hickson I.D. DNA helicase deficiencies associated with cancer predisposition and premature aging disorder. Hum. Mol. Genet. 10 (2001) 741-746
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 741-746
-
-
Mohaghegh, P.1
Hickson, I.D.2
-
6
-
-
0038288850
-
Association between osteosarcoma and deleterious mutations in the RecQL4 gene in Rothmund-Thomson syndrome
-
Wang L.L., Gannavarapu A., Kozinetz C.A., Levy M.L., Lewis R.A., Chintagumpala M.M., Ruiz-Maldanado R., Contreras-Ruiz J., Cunniff C., Erickson R.P., Lev D., Rogers M., Zackai E.H., and Plon S.E. Association between osteosarcoma and deleterious mutations in the RecQL4 gene in Rothmund-Thomson syndrome. J. Natl. Cancer Institute. 95 (2003) 669-674
-
(2003)
J. Natl. Cancer Institute.
, vol.95
, pp. 669-674
-
-
Wang, L.L.1
Gannavarapu, A.2
Kozinetz, C.A.3
Levy, M.L.4
Lewis, R.A.5
Chintagumpala, M.M.6
Ruiz-Maldanado, R.7
Contreras-Ruiz, J.8
Cunniff, C.9
Erickson, R.P.10
Lev, D.11
Rogers, M.12
Zackai, E.H.13
Plon, S.E.14
-
7
-
-
33745056414
-
Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer
-
Agrelo R., Cheng W.-H., Setien F., Ropero S., Espada J., Fraga M.F., Herranz M., Paz M.F., Sanchez-Cespedes M., Artiga M.J., Guerrero D., Castells A., von Kobbe C., Bohr V.A., and Esteller M. Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer. Proc. Natl. Acad. Sci. 103 (2006) 8822-8827
-
(2006)
Proc. Natl. Acad. Sci.
, vol.103
, pp. 8822-8827
-
-
Agrelo, R.1
Cheng, W.-H.2
Setien, F.3
Ropero, S.4
Espada, J.5
Fraga, M.F.6
Herranz, M.7
Paz, M.F.8
Sanchez-Cespedes, M.9
Artiga, M.J.10
Guerrero, D.11
Castells, A.12
von Kobbe, C.13
Bohr, V.A.14
Esteller, M.15
-
8
-
-
38949094875
-
-
P.L. Opresko Telomere ResQue and preservation--Roles for the Werner syndrome protein and other RecQ helicases, Mechanisms of Aging and Development 129 (2008) 79-90.
-
P.L. Opresko Telomere ResQue and preservation--Roles for the Werner syndrome protein and other RecQ helicases, Mechanisms of Aging and Development 129 (2008) 79-90.
-
-
-
-
9
-
-
34247390746
-
-
B.A. Kudlow, B.K. Kennedy and R.J. Monnat. Werner and Hutchinson-Gilford progeria syndromes: mechanistic basis of human progeroid diseases, 8 (2007) 394-404.
-
B.A. Kudlow, B.K. Kennedy and R.J. Monnat. Werner and Hutchinson-Gilford progeria syndromes: mechanistic basis of human progeroid diseases, 8 (2007) 394-404.
-
-
-
-
10
-
-
34547931623
-
Werner syndrome protein: functions in the response to DNA damage and replication stress in S phase
-
Cheng W.-H., Muftuoglu M., and Bohr V.A. Werner syndrome protein: functions in the response to DNA damage and replication stress in S phase. Exp. Gerontol. 42 (2007) 871-878
-
(2007)
Exp. Gerontol.
, vol.42
, pp. 871-878
-
-
Cheng, W.-H.1
Muftuoglu, M.2
Bohr, V.A.3
-
11
-
-
0022326116
-
Growth characteristics of Werner syndrome cells in vitro
-
Salk D., Bryant E., Hoehn H., Johnston P., and Martin G.M. Growth characteristics of Werner syndrome cells in vitro. Adv. Exp. Med. Biol. 190 (1985) 305-311
-
(1985)
Adv. Exp. Med. Biol.
, vol.190
, pp. 305-311
-
-
Salk, D.1
Bryant, E.2
Hoehn, H.3
Johnston, P.4
Martin, G.M.5
-
12
-
-
53149105231
-
Cell cycle analysis
-
Kruse P.F., and Patterson M.K. (Eds), Academic Press, New York
-
Macieira-Coelho A. Cell cycle analysis. In: Kruse P.F., and Patterson M.K. (Eds). Tissue Culture (1973), Academic Press, New York 412-422
-
(1973)
Tissue Culture
, pp. 412-422
-
-
Macieira-Coelho, A.1
-
13
-
-
0020306698
-
Prolongation of S phase and whole cell cycle in Werner's syndrome fibroblasts
-
Takeuchi F., Hanaoka F., Goto M., Yamada M., and Miyamoto T. Prolongation of S phase and whole cell cycle in Werner's syndrome fibroblasts. Exp. Gerontol. 17 (1982) 473-480
-
(1982)
Exp. Gerontol.
, vol.17
, pp. 473-480
-
-
Takeuchi, F.1
Hanaoka, F.2
Goto, M.3
Yamada, M.4
Miyamoto, T.5
-
14
-
-
0026702210
-
Impaired S phase transit of Werner syndrome cells expressed in lymphoblastoid cell lines
-
Poot M., Hoehn H., Runger T.M., and Martin G.M. Impaired S phase transit of Werner syndrome cells expressed in lymphoblastoid cell lines. Exp. Cell Res. 202 (1992) 267-273
-
(1992)
Exp. Cell Res.
, vol.202
, pp. 267-273
-
-
Poot, M.1
Hoehn, H.2
Runger, T.M.3
Martin, G.M.4
-
15
-
-
0023841617
-
BrdU-Hoechst flow cytometry: a unique tool for quantitative cell cycle analysis
-
Rabinovitch P.S., Kubbies M., Chen Y.C., Schindler D., and Hoehn H. BrdU-Hoechst flow cytometry: a unique tool for quantitative cell cycle analysis. Exp. Cell Res. 174 (1988) 309-318
-
(1988)
Exp. Cell Res.
, vol.174
, pp. 309-318
-
-
Rabinovitch, P.S.1
Kubbies, M.2
Chen, Y.C.3
Schindler, D.4
Hoehn, H.5
-
16
-
-
0345824623
-
Asymmetry of DNA replication fork progression in Werner's syndrome
-
Rodriguez-Lopez A., Jackson D., Iborra F., and Cox L. Asymmetry of DNA replication fork progression in Werner's syndrome. Aging Cell 1 (2002) 30-39
-
(2002)
Aging Cell
, vol.1
, pp. 30-39
-
-
Rodriguez-Lopez, A.1
Jackson, D.2
Iborra, F.3
Cox, L.4
-
17
-
-
33846428068
-
Functional role of the Werner syndrome RecQ helicase in human fibroblasts
-
Dhillon K.K., Sidorova J., Saintigny Y., Poot M., Gollahon K., Rabinovitch P.S., and Monnat R.J. Functional role of the Werner syndrome RecQ helicase in human fibroblasts. Aging Cell 6 (2007) 53-61
-
(2007)
Aging Cell
, vol.6
, pp. 53-61
-
-
Dhillon, K.K.1
Sidorova, J.2
Saintigny, Y.3
Poot, M.4
Gollahon, K.5
Rabinovitch, P.S.6
Monnat, R.J.7
-
18
-
-
42049116919
-
The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest
-
Sidorova J.M., Li N., Folch A., and Monnat Jr. R.J. The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest. Cell Cycle 7 (2008) 796-807
-
(2008)
Cell Cycle
, vol.7
, pp. 796-807
-
-
Sidorova, J.M.1
Li, N.2
Folch, A.3
Monnat Jr., R.J.4
-
19
-
-
34249716606
-
The role of cellular senescence in Werner syndrome: toward therapeutic intervention in human premature aging
-
Davis T., Wyllie F.S., Rokicki M.J., Bagley M.C., and Kipling D. The role of cellular senescence in Werner syndrome: toward therapeutic intervention in human premature aging. Ann. N.Y. Acad. Sci. 1100 (2007) 455-469
-
(2007)
Ann. N.Y. Acad. Sci.
, vol.1100
, pp. 455-469
-
-
Davis, T.1
Wyllie, F.S.2
Rokicki, M.J.3
Bagley, M.C.4
Kipling, D.5
-
20
-
-
27944477757
-
Werner protein protects non-proliferating cells from oxidative DNA damage
-
Szekely A.M., Bleichert F., Numann A., Van Komen S., Manasanch E., Ben Nasr A., Canaan A., and Weissman S.M. Werner protein protects non-proliferating cells from oxidative DNA damage. Mol. Cell. Biol. 25 (2005) 10492-10506
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 10492-10506
-
-
Szekely, A.M.1
Bleichert, F.2
Numann, A.3
Van Komen, S.4
Manasanch, E.5
Ben Nasr, A.6
Canaan, A.7
Weissman, S.M.8
-
21
-
-
0017668626
-
A retarded rate of DNA replication and normal level of DNA repair in Werner's syndrome fibroblasts in culture
-
Fujiwara Y., Higashikawa T., and Tatsumi M. A retarded rate of DNA replication and normal level of DNA repair in Werner's syndrome fibroblasts in culture. J. Cell Physiol. 92 (1977) 365-374
-
(1977)
J. Cell Physiol.
, vol.92
, pp. 365-374
-
-
Fujiwara, Y.1
Higashikawa, T.2
Tatsumi, M.3
-
22
-
-
0022294216
-
Abnormal fibroblast aging and DNA replication in the Werner syndrome
-
Fujiwara Y., Kano Y., Ichihashi M., Nakao Y., and Matsumura T. Abnormal fibroblast aging and DNA replication in the Werner syndrome. Adv. Exp. Med. Biol. 190 (1985) 459-477
-
(1985)
Adv. Exp. Med. Biol.
, vol.190
, pp. 459-477
-
-
Fujiwara, Y.1
Kano, Y.2
Ichihashi, M.3
Nakao, Y.4
Matsumura, T.5
-
23
-
-
0019979019
-
Altered frequency of initiation sites of DNA replication in Werner's syndrome cells
-
Takeuchi F., Hanaoka F., Goto M., Akaoka I., Hori T., Yamada M., and Miyamoto T. Altered frequency of initiation sites of DNA replication in Werner's syndrome cells. Hum. Genet. 60 (1982) 365-368
-
(1982)
Hum. Genet.
, vol.60
, pp. 365-368
-
-
Takeuchi, F.1
Hanaoka, F.2
Goto, M.3
Akaoka, I.4
Hori, T.5
Yamada, M.6
Miyamoto, T.7
-
24
-
-
0024291357
-
A replication fork barrier at the 3′ end of yeast ribosomal RNA genes
-
Brewer B.J., and Fangman W.L. A replication fork barrier at the 3′ end of yeast ribosomal RNA genes. Cell 55 (1988) 637-643
-
(1988)
Cell
, vol.55
, pp. 637-643
-
-
Brewer, B.J.1
Fangman, W.L.2
-
25
-
-
23944507608
-
Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork
-
Calzada A., Hodgson B., Kanemaki M., Bueno A., and Labib K. Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork. Genes Dev. 19 (2005) 1905-1919
-
(2005)
Genes Dev.
, vol.19
, pp. 1905-1919
-
-
Calzada, A.1
Hodgson, B.2
Kanemaki, M.3
Bueno, A.4
Labib, K.5
-
26
-
-
21244448288
-
Checkpoint responses to replication fork barriers
-
Lambert S., and Carr A.M. Checkpoint responses to replication fork barriers. Biochemistry 87 (2005) 591-602
-
(2005)
Biochemistry
, vol.87
, pp. 591-602
-
-
Lambert, S.1
Carr, A.M.2
-
27
-
-
34249944668
-
Arrested replication fork processing: interplay between checkpoints and recombination
-
Lambert S., Froget B., and Carr A.M. Arrested replication fork processing: interplay between checkpoints and recombination. DNA Repair 6 (2007) 1042-1061
-
(2007)
DNA Repair
, vol.6
, pp. 1042-1061
-
-
Lambert, S.1
Froget, B.2
Carr, A.M.3
-
29
-
-
1542723574
-
AT islands - their nature and potential for anticancer strategies
-
Woynarowski J. AT islands - their nature and potential for anticancer strategies. Curr. Cancer Drug Targets 4 (2004) 219-234
-
(2004)
Curr. Cancer Drug Targets
, vol.4
, pp. 219-234
-
-
Woynarowski, J.1
-
30
-
-
34347238951
-
Hairpin- and cruciform-mediated chromosome breakage: causes and consequences in eukaryotic cells
-
Lobachev K.S., Rattray A., and Narayanan V. Hairpin- and cruciform-mediated chromosome breakage: causes and consequences in eukaryotic cells. Front. Biosci. 12 (2007) 4208-4220
-
(2007)
Front. Biosci.
, vol.12
, pp. 4208-4220
-
-
Lobachev, K.S.1
Rattray, A.2
Narayanan, V.3
-
31
-
-
33744807443
-
DNA structures, repeat expansions and human hereditary disorders
-
Mirkin S.M. DNA structures, repeat expansions and human hereditary disorders. Curr. Opin. Struct. Biol. 16 (2006) 351-358
-
(2006)
Curr. Opin. Struct. Biol.
, vol.16
, pp. 351-358
-
-
Mirkin, S.M.1
-
35
-
-
33746495515
-
Depletion of CHK1, but not CHK2, induces chromosomal instability and breaks at common fragile sites
-
Durkin S.G., Arlt M.F., Howlett N.G., and Glover T.W. Depletion of CHK1, but not CHK2, induces chromosomal instability and breaks at common fragile sites. Oncogene 25 (2006) 4381-4388
-
(2006)
Oncogene
, vol.25
, pp. 4381-4388
-
-
Durkin, S.G.1
Arlt, M.F.2
Howlett, N.G.3
Glover, T.W.4
-
36
-
-
0034681257
-
The Saccharomyces Pif1p DNA helicase and the highly related Rrm3p have opposite effects on replication fork progression in ribosomal DNA
-
Ivessa A.S., Zhou J.-Q., and Zakian V.A. The Saccharomyces Pif1p DNA helicase and the highly related Rrm3p have opposite effects on replication fork progression in ribosomal DNA. Cell 100 (2000) 479-489
-
(2000)
Cell
, vol.100
, pp. 479-489
-
-
Ivessa, A.S.1
Zhou, J.-Q.2
Zakian, V.A.3
-
37
-
-
0038604455
-
DNA2 helicase/nuclease causes replicative fork stalling and double-strand breaks in the ribosomal DNA of saccharomyces cerevisiae
-
Weitao T., Budd M., Hoopes L.L.M., and Campbell J.L. DNA2 helicase/nuclease causes replicative fork stalling and double-strand breaks in the ribosomal DNA of saccharomyces cerevisiae. J. Biol. Chem. 278 (2003) 22513-22522
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 22513-22522
-
-
Weitao, T.1
Budd, M.2
Hoopes, L.L.M.3
Campbell, J.L.4
-
38
-
-
10344256183
-
Defective telomere lagging strand synthesis in cells lacking WRN helicase activity
-
Crabbe L., Verdun R.E., Haggblom C.I., and Karlseder J. Defective telomere lagging strand synthesis in cells lacking WRN helicase activity. Science 306 (2004) 1951-1953
-
(2004)
Science
, vol.306
, pp. 1951-1953
-
-
Crabbe, L.1
Verdun, R.E.2
Haggblom, C.I.3
Karlseder, J.4
-
39
-
-
23744470383
-
Human ribosomal RNA gene arrays display a broad range of palindromic structures
-
Caburet S., Conti C., Schurra C., Lebofsky R., Edelstein S.J., and Bensimon A. Human ribosomal RNA gene arrays display a broad range of palindromic structures. Genome Res. 15 (2005) 1079-1085
-
(2005)
Genome Res.
, vol.15
, pp. 1079-1085
-
-
Caburet, S.1
Conti, C.2
Schurra, C.3
Lebofsky, R.4
Edelstein, S.J.5
Bensimon, A.6
-
40
-
-
0034486160
-
Spectral karyotyping of Werner syndrome fibroblast cultures
-
Melcher R., von Golitschek R., Steinlein C., Schindler D., Neitzel H., Kainer K., Schmid M., and Hoehn H. Spectral karyotyping of Werner syndrome fibroblast cultures. Cytogenet. Genome Res. 91 (2000) 180-185
-
(2000)
Cytogenet. Genome Res.
, vol.91
, pp. 180-185
-
-
Melcher, R.1
von Golitschek, R.2
Steinlein, C.3
Schindler, D.4
Neitzel, H.5
Kainer, K.6
Schmid, M.7
Hoehn, H.8
-
41
-
-
38749136967
-
Werner syndrome helicase activity is essential in maintaining fragile site stability
-
Pirzio L.M., Pichierri P., Bignami M., and Franchitto A. Werner syndrome helicase activity is essential in maintaining fragile site stability. J. Cell Biol. 180 (2008) 305-314
-
(2008)
J. Cell Biol.
, vol.180
, pp. 305-314
-
-
Pirzio, L.M.1
Pichierri, P.2
Bignami, M.3
Franchitto, A.4
-
42
-
-
34547205070
-
An AT-rich sequence in human common fragile site FRA16D causes fork stalling and chromosome breakage in S. cerevisiae
-
Zhang H., and Freudenreich C.H. An AT-rich sequence in human common fragile site FRA16D causes fork stalling and chromosome breakage in S. cerevisiae. Mol. Cell 27 (2007) 367-379
-
(2007)
Mol. Cell
, vol.27
, pp. 367-379
-
-
Zhang, H.1
Freudenreich, C.H.2
-
43
-
-
0033617316
-
HumanWerner syndrome DNA helicase unwinds tetrahelical structures of the fragile x syndrome repeat sequence d(CGG)n
-
Fry M., and Loeb L.A. HumanWerner syndrome DNA helicase unwinds tetrahelical structures of the fragile x syndrome repeat sequence d(CGG)n. J. Biol. Chem. 274 (1999) 12797-12802
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 12797-12802
-
-
Fry, M.1
Loeb, L.A.2
-
44
-
-
0038298811
-
XRCC3 and Rad51 modulate replication fork progression on damaged vertebrate chromosomes
-
Henry-Mowatt J., Jackson D., Masson J.Y., Johnson P.A., Clements P.M., Benson F.E., Thompson L.H., Takeda S., West S.C., and Caldecott K.W. XRCC3 and Rad51 modulate replication fork progression on damaged vertebrate chromosomes. Mol. Cell. 11 (2003) 1109-1117
-
(2003)
Mol. Cell.
, vol.11
, pp. 1109-1117
-
-
Henry-Mowatt, J.1
Jackson, D.2
Masson, J.Y.3
Johnson, P.A.4
Clements, P.M.5
Benson, F.E.6
Thompson, L.H.7
Takeda, S.8
West, S.C.9
Caldecott, K.W.10
-
45
-
-
16544387211
-
A method to monitor replication fork progression in mammalian cells: nucleotide excision repair enhances and homologous recombination delays elongation along damaged DNA
-
e157-
-
Johansson F., Lagerqvist A., Erixon K., and Jenssen D. A method to monitor replication fork progression in mammalian cells: nucleotide excision repair enhances and homologous recombination delays elongation along damaged DNA. Nucl. Acids Res. 32 (2004) e157-
-
(2004)
Nucl. Acids Res.
, vol.32
-
-
Johansson, F.1
Lagerqvist, A.2
Erixon, K.3
Jenssen, D.4
-
46
-
-
34547902426
-
The intra-S phase checkpoint affects both DNA replication initiation and elongation: single-cell and -DNA fiber analyses
-
Seiler J.A., Conti C., Syed A., Aladjem M.I., and Pommier Y. The intra-S phase checkpoint affects both DNA replication initiation and elongation: single-cell and -DNA fiber analyses. Mol. Cell. Biol. 27 (2007) 5806-5818
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 5806-5818
-
-
Seiler, J.A.1
Conti, C.2
Syed, A.3
Aladjem, M.I.4
Pommier, Y.5
-
47
-
-
37249004667
-
The mammalian DNA replication elongation checkpoint: implication of Chk1 and relationship with origin firing as determined by single DNA molecule and single cell analyses
-
Epub 2007 Aug 2722
-
Conti C., Seiler J.A., and Pommier Y. The mammalian DNA replication elongation checkpoint: implication of Chk1 and relationship with origin firing as determined by single DNA molecule and single cell analyses. Cell Cycle 6 (2007) 2760-2767 Epub 2007 Aug 2722
-
(2007)
Cell Cycle
, vol.6
, pp. 2760-2767
-
-
Conti, C.1
Seiler, J.A.2
Pommier, Y.3
-
48
-
-
29544437558
-
Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions
-
Lopes M., Foiani M., and Sogo J.M. Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions. Mol. Cell 21 (2006) 15-27
-
(2006)
Mol. Cell
, vol.21
, pp. 15-27
-
-
Lopes, M.1
Foiani, M.2
Sogo, J.M.3
-
49
-
-
0017298802
-
A model for replication repair in mammalian cells
-
Higgins N.P., Kato K., and Strauss B. A model for replication repair in mammalian cells. J. Mol. Biol. 101 (1976) 417-425
-
(1976)
J. Mol. Biol.
, vol.101
, pp. 417-425
-
-
Higgins, N.P.1
Kato, K.2
Strauss, B.3
-
50
-
-
0017011479
-
Replicative repair of UV damage to normal human cells
-
Fujiwara Y., and Tatsumi M. Replicative repair of UV damage to normal human cells. Mutat. Res. 38 (1976) 335-336
-
(1976)
Mutat. Res.
, vol.38
, pp. 335-336
-
-
Fujiwara, Y.1
Tatsumi, M.2
-
51
-
-
0347416973
-
Branch migrating sister chromatid junctions form at replication origins through Rad51/Rad52-independent mechanisms
-
Lopes M., Cotta-Ramusino C., Liberi G., and Foiani M. Branch migrating sister chromatid junctions form at replication origins through Rad51/Rad52-independent mechanisms. Mol. Cell 12 (2003) 1499-1510
-
(2003)
Mol. Cell
, vol.12
, pp. 1499-1510
-
-
Lopes, M.1
Cotta-Ramusino, C.2
Liberi, G.3
Foiani, M.4
-
52
-
-
19944432787
-
Rad51-dependent DNA structures accumulate at damaged replication forks in sgs1 mutants defective in the yeast ortholog of BLM RecQ helicase
-
Liberi G., Maffioletti G., Lucca C., Chiolo I., Baryshnikova A., Cotta-Ramusino C., Lopes M., Pellicioli A., Haber J.E., and Foiani M. Rad51-dependent DNA structures accumulate at damaged replication forks in sgs1 mutants defective in the yeast ortholog of BLM RecQ helicase. Genes Dev. 19 (2005) 339-350
-
(2005)
Genes Dev.
, vol.19
, pp. 339-350
-
-
Liberi, G.1
Maffioletti, G.2
Lucca, C.3
Chiolo, I.4
Baryshnikova, A.5
Cotta-Ramusino, C.6
Lopes, M.7
Pellicioli, A.8
Haber, J.E.9
Foiani, M.10
-
53
-
-
34249936595
-
Minding the gap: the underground functions of BRCA1 and BRCA2 at stalled replication forks
-
Nagaraju G., and Scully R. Minding the gap: the underground functions of BRCA1 and BRCA2 at stalled replication forks. DNA Repair 6 (2007) 1018-1031
-
(2007)
DNA Repair
, vol.6
, pp. 1018-1031
-
-
Nagaraju, G.1
Scully, R.2
-
54
-
-
33847413700
-
A critical role for the ubiquitin-conjugating enzyme ubc13 in initiating homologous recombination
-
Zhao G.Y., Sonoda E., Barber L.J., Oka H., Murakawa Y., Yamada K., Ikura T., Wang X., Kobayashi M., Yamamoto K., Boulton S.J., and Takeda S. A critical role for the ubiquitin-conjugating enzyme ubc13 in initiating homologous recombination. Mol. Cell 25 (2007) 663-675
-
(2007)
Mol. Cell
, vol.25
, pp. 663-675
-
-
Zhao, G.Y.1
Sonoda, E.2
Barber, L.J.3
Oka, H.4
Murakawa, Y.5
Yamada, K.6
Ikura, T.7
Wang, X.8
Kobayashi, M.9
Yamamoto, K.10
Boulton, S.J.11
Takeda, S.12
-
55
-
-
34249945536
-
DNA double-strand break repair: From mechanistic understanding to cancer treatment
-
Helleday T., Lo J., van Gent D.C., and Engelward B.P. DNA double-strand break repair: From mechanistic understanding to cancer treatment. DNA Repair 6 (2007) 923-935
-
(2007)
DNA Repair
, vol.6
, pp. 923-935
-
-
Helleday, T.1
Lo, J.2
van Gent, D.C.3
Engelward, B.P.4
-
56
-
-
35649025318
-
Requirement of RAD52 group genes for postreplication repair of UV-damaged DNA in saccharomyces cerevisiae
-
Gangavarapu V., Prakash S., and Prakash L. Requirement of RAD52 group genes for postreplication repair of UV-damaged DNA in saccharomyces cerevisiae. Mol. Cell. Biol. 27 (2007) 7758-7764
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 7758-7764
-
-
Gangavarapu, V.1
Prakash, S.2
Prakash, L.3
-
57
-
-
34249941966
-
Translesion synthesis: Y-family polymerases and the polymerase switch
-
Lehmann A.R., Niimi A., Ogi T., Brown S., Sabbioneda S., Wing J.F., Kannouche P.L., and Green C.M. Translesion synthesis: Y-family polymerases and the polymerase switch. DNA Repair 6 (2007) 891-899
-
(2007)
DNA Repair
, vol.6
, pp. 891-899
-
-
Lehmann, A.R.1
Niimi, A.2
Ogi, T.3
Brown, S.4
Sabbioneda, S.5
Wing, J.F.6
Kannouche, P.L.7
Green, C.M.8
-
58
-
-
33847775919
-
Upregulation of error-prone DNA polymerases beta and kappa slows down fork progression without activating the replication checkpoint
-
Epub 2007 Feb2019
-
Pillaire M.J., Betous R., Conti C., Czaplicki J., Pasero P., Bensimon A., Cazaux C., and Hoffmann J.S. Upregulation of error-prone DNA polymerases beta and kappa slows down fork progression without activating the replication checkpoint. Cell Cycle 6 (2007) 471-477 Epub 2007 Feb2019
-
(2007)
Cell Cycle
, vol.6
, pp. 471-477
-
-
Pillaire, M.J.1
Betous, R.2
Conti, C.3
Czaplicki, J.4
Pasero, P.5
Bensimon, A.6
Cazaux, C.7
Hoffmann, J.S.8
-
59
-
-
28444462167
-
Dual roles for DNA polymerase [eta] in homologous DNA recombination and translesion DNA synthesis
-
Kawamoto T., Araki K., Sonoda E., Yamashita Y.M., Harada K., Kikuchi K., Masutani C., Hanaoka F., Nozaki K., Hashimoto N., and Takeda S. Dual roles for DNA polymerase [eta] in homologous DNA recombination and translesion DNA synthesis. Mol. Cell 20 (2005) 793-799
-
(2005)
Mol. Cell
, vol.20
, pp. 793-799
-
-
Kawamoto, T.1
Araki, K.2
Sonoda, E.3
Yamashita, Y.M.4
Harada, K.5
Kikuchi, K.6
Masutani, C.7
Hanaoka, F.8
Nozaki, K.9
Hashimoto, N.10
Takeda, S.11
-
60
-
-
28444470501
-
DNA polymerase [eta] promotes DNA synthesis from strand invasion intermediates of homologous recombination
-
McIlwraith M.J., Vaisman A., Liu Y., Fanning E., Woodgate R., and West Human S.C. DNA polymerase [eta] promotes DNA synthesis from strand invasion intermediates of homologous recombination. Mol. Cell 20 (2005) 783-792
-
(2005)
Mol. Cell
, vol.20
, pp. 783-792
-
-
McIlwraith, M.J.1
Vaisman, A.2
Liu, Y.3
Fanning, E.4
Woodgate, R.5
West Human, S.C.6
-
61
-
-
39549114273
-
DNA repair synthesis facilitates RAD52-mediated second-end capture during DSB repair
-
McIlwraith M.J., and West S.C. DNA repair synthesis facilitates RAD52-mediated second-end capture during DSB repair. Mol. Cell 29 (2008) 510-516
-
(2008)
Mol. Cell
, vol.29
, pp. 510-516
-
-
McIlwraith, M.J.1
West, S.C.2
-
62
-
-
0031686571
-
The premature aging syndrome protein, WRN, is a 3′-- > 5′ exonuclease
-
Huang S., Li B., Gray M.D., Oshima J., Mian I.S., and Campisi J. The premature aging syndrome protein, WRN, is a 3′-- > 5′ exonuclease. Nat. Genet. 20 (1998) 114-116
-
(1998)
Nat. Genet.
, vol.20
, pp. 114-116
-
-
Huang, S.1
Li, B.2
Gray, M.D.3
Oshima, J.4
Mian, I.S.5
Campisi, J.6
-
63
-
-
0032545423
-
Werner syndrome protein. II. Characterization of the integral 3′ -- > 5′ DNA exonuclease
-
Kamath-Loeb A.S., Shen J.C., Loeb L.A., and Fry M. Werner syndrome protein. II. Characterization of the integral 3′ -- > 5′ DNA exonuclease. J. Biol. Chem. 273 (1998) 34145-34150
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 34145-34150
-
-
Kamath-Loeb, A.S.1
Shen, J.C.2
Loeb, L.A.3
Fry, M.4
-
64
-
-
0032545515
-
Werner syndrome protein. I. DNA helicase and DNA exonuclease reside on the same polypeptide
-
Shen J.C., Gray M.D., Oshima J., Kamath-Loeb A.S., Fry M., and Loeb L.A. Werner syndrome protein. I. DNA helicase and DNA exonuclease reside on the same polypeptide. J. Biol. Chem. 273 (1998) 34139-34144
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 34139-34144
-
-
Shen, J.C.1
Gray, M.D.2
Oshima, J.3
Kamath-Loeb, A.S.4
Fry, M.5
Loeb, L.A.6
-
65
-
-
0030751354
-
The Werner syndrome protein is a DNA helicase
-
Gray M.D., Shen J.-C., Kamath-Loeb A.S., Blank A., Sopher B.L., Martin G.M., Oshima J., and Loeb L.A. The Werner syndrome protein is a DNA helicase. Nat. Genet. 17 (1997) 100-103
-
(1997)
Nat. Genet.
, vol.17
, pp. 100-103
-
-
Gray, M.D.1
Shen, J.-C.2
Kamath-Loeb, A.S.3
Blank, A.4
Sopher, B.L.5
Martin, G.M.6
Oshima, J.7
Loeb, L.A.8
-
66
-
-
0030757524
-
DNA helicase activity in Werner's syndrome gene product synthesized in a baculovirus system
-
Suzuki N., Shimamoto A., Imamura O., Kuromitsu J., Kitao S., Goto M., and Furuichi Y. DNA helicase activity in Werner's syndrome gene product synthesized in a baculovirus system. Nucl. Acids Res. 25 (1997) 2973-2978
-
(1997)
Nucl. Acids Res.
, vol.25
, pp. 2973-2978
-
-
Suzuki, N.1
Shimamoto, A.2
Imamura, O.3
Kuromitsu, J.4
Kitao, S.5
Goto, M.6
Furuichi, Y.7
-
67
-
-
0347362703
-
Werner syndrome protein contains three structure-specific DNA binding domains
-
von Kobbe C., Thoma N.H., Czyzewski B.K., Pavletich N.P., and Bohr V.A. Werner syndrome protein contains three structure-specific DNA binding domains. J. Biol. Chem. 278 (2003) 52997-53006
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 52997-53006
-
-
von Kobbe, C.1
Thoma, N.H.2
Czyzewski, B.K.3
Pavletich, N.P.4
Bohr, V.A.5
-
68
-
-
20744437108
-
RecQ family members combine strand pairing and unwinding activities to catalyze strand exchange
-
Machwe A., Xiao L., Groden J., Matson S.W., and Orren D.K. RecQ family members combine strand pairing and unwinding activities to catalyze strand exchange. J. Biol. Chem. 280 (2005) 23397-23407
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 23397-23407
-
-
Machwe, A.1
Xiao, L.2
Groden, J.3
Matson, S.W.4
Orren, D.K.5
-
69
-
-
33751581731
-
The Werner and Bloom syndrome proteins catalyze regression of a model replication fork
-
Machwe A., Xiao L., Groden J., and Orren D.K. The Werner and Bloom syndrome proteins catalyze regression of a model replication fork. Biochemistry 45 (2006) 13939-13946
-
(2006)
Biochemistry
, vol.45
, pp. 13939-13946
-
-
Machwe, A.1
Xiao, L.2
Groden, J.3
Orren, D.K.4
-
70
-
-
34848880201
-
Replication fork regression in vitro by the Werner syndrome protein (WRN): Holliday junction formation, the effect of leading arm structure and a potential role for WRN exonuclease activity
-
Machwe A., Xiao L., Lloyd R.G., Bolt E., and Orren D.K. Replication fork regression in vitro by the Werner syndrome protein (WRN): Holliday junction formation, the effect of leading arm structure and a potential role for WRN exonuclease activity. Nucl. Acids Res. 35 (2007) 5729-5747
-
(2007)
Nucl. Acids Res.
, vol.35
, pp. 5729-5747
-
-
Machwe, A.1
Xiao, L.2
Lloyd, R.G.3
Bolt, E.4
Orren, D.K.5
-
71
-
-
0034231844
-
Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest
-
Constantinou A., Tarsounas M., Karow J.K., Brosh R.M., Bohr V.A., Hickson I.D., and West S.C. Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest. EMBO. Reports. 1 (2000) 80-84
-
(2000)
EMBO. Reports.
, vol.1
, pp. 80-84
-
-
Constantinou, A.1
Tarsounas, M.2
Karow, J.K.3
Brosh, R.M.4
Bohr, V.A.5
Hickson, I.D.6
West, S.C.7
-
72
-
-
0742288051
-
WRN helicase and FEN-1 form a complex upon replication arrest and together process branch-migrating DNA structures associated with the replication fork
-
Sharma S., Otterlei M., Sommers J.A., Driscoll H.C., Dianov G.L., Kao H.-I., Bambara R.A., and Brosh Jr. R.M. WRN helicase and FEN-1 form a complex upon replication arrest and together process branch-migrating DNA structures associated with the replication fork. Mol. Biol. Cell (2004) 734-750
-
(2004)
Mol. Biol. Cell
, pp. 734-750
-
-
Sharma, S.1
Otterlei, M.2
Sommers, J.A.3
Driscoll, H.C.4
Dianov, G.L.5
Kao, H.-I.6
Bambara, R.A.7
Brosh Jr., R.M.8
-
73
-
-
0037137177
-
The Werner syndrome helicase/exonuclease (WRN) disrupts and degrades D-loops in vitro
-
Orren D.K., Theodore S., and Machwe A. The Werner syndrome helicase/exonuclease (WRN) disrupts and degrades D-loops in vitro. Biochemistry. 41 (2002) 13483-13488
-
(2002)
Biochemistry.
, vol.41
, pp. 13483-13488
-
-
Orren, D.K.1
Theodore, S.2
Machwe, A.3
-
74
-
-
34547525678
-
Werner syndrome protein interacts functionally with translesion DNA polymerases
-
Kamath-Loeb A.S., Lan L., Nakajima S., Yasui A., and Loeb L.A. Werner syndrome protein interacts functionally with translesion DNA polymerases. Proc. Natl. Acad. Sci. 104 (2007) 10394-10399
-
(2007)
Proc. Natl. Acad. Sci.
, vol.104
, pp. 10394-10399
-
-
Kamath-Loeb, A.S.1
Lan, L.2
Nakajima, S.3
Yasui, A.4
Loeb, L.A.5
-
75
-
-
32644449296
-
The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase {beta}
-
Harrigan J.A., Wilson III D.M., Prasad R., Opresko P.L., Beck G., May A., Wilson S.H., and Bohr V.A. The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase {beta}. Nucl. Acids Res. 34 (2006) 745-754
-
(2006)
Nucl. Acids Res.
, vol.34
, pp. 745-754
-
-
Harrigan, J.A.1
Wilson III, D.M.2
Prasad, R.3
Opresko, P.L.4
Beck, G.5
May, A.6
Wilson, S.H.7
Bohr, V.A.8
-
76
-
-
0035844242
-
Interactions between the Werner syndrome helicase and DNA polymerase delta specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)n trinucleotide repeat sequence
-
Kamath-Loeb A.S., Loeb L.A., Johansson E., Burgers P.M.J., and Fry M. Interactions between the Werner syndrome helicase and DNA polymerase delta specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)n trinucleotide repeat sequence. J. Biol. Chem. 276 (2001) 16439-16446
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 16439-16446
-
-
Kamath-Loeb, A.S.1
Loeb, L.A.2
Johansson, E.3
Burgers, P.M.J.4
Fry, M.5
-
77
-
-
0040436076
-
Functional and physical interaction between WRN helicase and human replication protein A
-
Brosh Jr. R.M., Orren D.K., Nehlin J.O., Ravn P.H., Kenny M.K., Machwe A., and Bohr V.A. Functional and physical interaction between WRN helicase and human replication protein A. J. Biol. Chem. 274 (1999) 18341-18350
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 18341-18350
-
-
Brosh Jr., R.M.1
Orren, D.K.2
Nehlin, J.O.3
Ravn, P.H.4
Kenny, M.K.5
Machwe, A.6
Bohr, V.A.7
-
78
-
-
0141853230
-
The N-terminal domain of the large subunit of human replication protein A binds to Werner syndrome protein and stimulates helicase activity
-
Shen J.-C., Lao Y., Kamath-Loeb A., Wold M.S., and Loeb L.A. The N-terminal domain of the large subunit of human replication protein A binds to Werner syndrome protein and stimulates helicase activity. Mech. Aging Dev. 124 (2003) 921-930
-
(2003)
Mech. Aging Dev.
, vol.124
, pp. 921-930
-
-
Shen, J.-C.1
Lao, Y.2
Kamath-Loeb, A.3
Wold, M.S.4
Loeb, L.A.5
-
79
-
-
23044449149
-
Multiple but dissectible functions of FEN-1 nucleases in nucleic acid processing, genome stability and diseases
-
Shen B., Singh P., Liu R., Qiu J., Zheng L., Finger L.D., and Alas S. Multiple but dissectible functions of FEN-1 nucleases in nucleic acid processing, genome stability and diseases. BioEssays 27 (2005) 717-729
-
(2005)
BioEssays
, vol.27
, pp. 717-729
-
-
Shen, B.1
Singh, P.2
Liu, R.3
Qiu, J.4
Zheng, L.5
Finger, L.D.6
Alas, S.7
-
80
-
-
0034595842
-
Inhibition of flap endonuclease 1 by flap secondary structure and relevance to repeat sequence expansion
-
Henricksen L.A., Tom S., Liu Y., and Bambara R.A. Inhibition of flap endonuclease 1 by flap secondary structure and relevance to repeat sequence expansion. J. Biol. Chem. 275 (2000) 16420-16427
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 16420-16427
-
-
Henricksen, L.A.1
Tom, S.2
Liu, Y.3
Bambara, R.A.4
-
81
-
-
0035887046
-
Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity
-
Brosh Jr. R.M., von Kobbe C., Sommers J.A., Karmakar P., Opresko P.L., Piotrowski J., Dianova I., Dianov G.L., and Bohr V.A. Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity. EMBO. J. 20 (2001) 5791-5801
-
(2001)
EMBO. J.
, vol.20
, pp. 5791-5801
-
-
Brosh Jr., R.M.1
von Kobbe, C.2
Sommers, J.A.3
Karmakar, P.4
Opresko, P.L.5
Piotrowski, J.6
Dianova, I.7
Dianov, G.L.8
Bohr, V.A.9
-
82
-
-
0037044311
-
Biochemical characterization of the WRN-FEN-1 functional interaction
-
Brosh R.M., Driscoll H.C., Dianov G.L., and Sommers J.A. Biochemical characterization of the WRN-FEN-1 functional interaction. Biochemistry 41 (2002) 12204-12216
-
(2002)
Biochemistry
, vol.41
, pp. 12204-12216
-
-
Brosh, R.M.1
Driscoll, H.C.2
Dianov, G.L.3
Sommers, J.A.4
-
83
-
-
53149143613
-
RecQ helicases: guardian angels of the DNA replication fork
-
Bachrati C.Z., and Hickson I.D. RecQ helicases: guardian angels of the DNA replication fork. Chromosoma 11 (2008) 11
-
(2008)
Chromosoma
, vol.11
, pp. 11
-
-
Bachrati, C.Z.1
Hickson, I.D.2
-
84
-
-
0037593470
-
The Exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome protein
-
Sharma S., Sommers J.A., Driscoll H.C., Uzdilla L., Wilson T.M., and Brosh Jr. R.M. The Exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome protein. J. Biol. Chem. 278 (2003) 23487-23496
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 23487-23496
-
-
Sharma, S.1
Sommers, J.A.2
Driscoll, H.C.3
Uzdilla, L.4
Wilson, T.M.5
Brosh Jr., R.M.6
-
85
-
-
5444272914
-
In vivo function of the conserved non-catalytic domain of Werner syndrome helicase in DNA replication
-
Sharma S., Sommers J.A., and Brosh Jr. R.M. In vivo function of the conserved non-catalytic domain of Werner syndrome helicase in DNA replication. Hum. Mol. Genet. 13 (2004) 2247-2261
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 2247-2261
-
-
Sharma, S.1
Sommers, J.A.2
Brosh Jr., R.M.3
-
86
-
-
32644454570
-
Sumoylation of PCNA: wrestling with recombination at stalled replication forks
-
Watts F.Z. Sumoylation of PCNA: wrestling with recombination at stalled replication forks. DNA Repair 5 (2006) 399-403
-
(2006)
DNA Repair
, vol.5
, pp. 399-403
-
-
Watts, F.Z.1
-
87
-
-
38049123477
-
Eukaryotic DNA damage tolerance and translesion synthesis through covalent modifications of PCNA
-
Andersen P., Xu F., and Xiao W. Eukaryotic DNA damage tolerance and translesion synthesis through covalent modifications of PCNA. Cell Res. 18 (2008) 162-173
-
(2008)
Cell Res.
, vol.18
, pp. 162-173
-
-
Andersen, P.1
Xu, F.2
Xiao, W.3
-
88
-
-
33845310025
-
Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination
-
Motegi A., Sood R., Moinova H., Markowitz S.D., Liu P.P., and Myung K. Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination. J. Cell Biol. 175 (2006) 703-708
-
(2006)
J. Cell Biol.
, vol.175
, pp. 703-708
-
-
Motegi, A.1
Sood, R.2
Moinova, H.3
Markowitz, S.D.4
Liu, P.P.5
Myung, K.6
-
89
-
-
35148847451
-
Yeast Rad5 protein required for postreplication repair has a DNA helicase activity specific for replication fork regression
-
Blastyák A., Pintér L., Unk I., Prakash L., Prakash S., and Haracska L. Yeast Rad5 protein required for postreplication repair has a DNA helicase activity specific for replication fork regression. Mol. Cell 28 (2007) 167-175
-
(2007)
Mol. Cell
, vol.28
, pp. 167-175
-
-
Blastyák, A.1
Pintér, L.2
Unk, I.3
Prakash, L.4
Prakash, S.5
Haracska, L.6
-
90
-
-
22944474665
-
SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase
-
Pfander B., Moldovan G.-L., Sacher M., Hoege C., and Jentsch S. SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase. Nature 436 (2005) 428-433
-
(2005)
Nature
, vol.436
, pp. 428-433
-
-
Pfander, B.1
Moldovan, G.-L.2
Sacher, M.3
Hoege, C.4
Jentsch, S.5
-
91
-
-
21244449061
-
Crosstalk between SUMO and ubiquitin on PCNA is mediated by recruitment of the helicase Srs2p
-
Papouli E., Chen S., Davies A.A., Huttner D., Krejci L., Sung P., and Ulrich H.D. Crosstalk between SUMO and ubiquitin on PCNA is mediated by recruitment of the helicase Srs2p. Mol. Cell 19 (2005) 123-133
-
(2005)
Mol. Cell
, vol.19
, pp. 123-133
-
-
Papouli, E.1
Chen, S.2
Davies, A.A.3
Huttner, D.4
Krejci, L.5
Sung, P.6
Ulrich, H.D.7
-
92
-
-
33750437743
-
Ubc9- and mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks
-
Branzei D., Sollier J., Liberi G., Zhao X., Maeda D., Seki M., Enomoto T., Ohta K., and Foiani M. Ubc9- and mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks. Cell. 127 (2006) 509-522
-
(2006)
Cell.
, vol.127
, pp. 509-522
-
-
Branzei, D.1
Sollier, J.2
Liberi, G.3
Zhao, X.4
Maeda, D.5
Seki, M.6
Enomoto, T.7
Ohta, K.8
Foiani, M.9
-
93
-
-
0034647556
-
Covalent modification of the werner's syndrome gene product with the ubiquitin-related protein, SUMO-1
-
Kawabe Y.-i., Seki M., Seki T., Wang W.-S., Imamura O., Furuichi Y., Saitoh H., and Enomoto T. Covalent modification of the werner's syndrome gene product with the ubiquitin-related protein, SUMO-1. J. Biol. Chem. 275 (2000) 20963-20966
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 20963-20966
-
-
Kawabe, Y.-i.1
Seki, M.2
Seki, T.3
Wang, W.-S.4
Imamura, O.5
Furuichi, Y.6
Saitoh, H.7
Enomoto, T.8
-
94
-
-
9644290910
-
p14 Arf promotes small ubiquitin-like modifier conjugation of Werners helicase
-
Woods Y.L., Xirodimas D.P., Prescott A.R., Sparks A., Lane D.P., and Saville M.K. p14 Arf promotes small ubiquitin-like modifier conjugation of Werners helicase. J. Biol. Chem. 279 (2004) 50157-50166
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 50157-50166
-
-
Woods, Y.L.1
Xirodimas, D.P.2
Prescott, A.R.3
Sparks, A.4
Lane, D.P.5
Saville, M.K.6
-
95
-
-
34249996787
-
WRN functions in a RAD18-dependent damage avoidance pathway
-
Dong Y.P., Seki M., Yoshimura A., Inoue E., Furukawa S., Tada S., and Enomoto T. WRN functions in a RAD18-dependent damage avoidance pathway. Biol. Pharm. Bull. 30 (2007) 1080-1083
-
(2007)
Biol. Pharm. Bull.
, vol.30
, pp. 1080-1083
-
-
Dong, Y.P.1
Seki, M.2
Yoshimura, A.3
Inoue, E.4
Furukawa, S.5
Tada, S.6
Enomoto, T.7
-
96
-
-
0035827598
-
A novel protein interacts with the Werner's syndrome gene product physically and functionally
-
Kawabe Y.-i., Branzei D., Hayashi T., Suzuki H., Masuko T., Onoda F., Heo S.-J., Ikeda H., Shimamoto A., Furuichi Y., Seki M., and Enomoto T. A novel protein interacts with the Werner's syndrome gene product physically and functionally. J. Biol. Chem. 276 (2001) 20364-20369
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20364-20369
-
-
Kawabe, Y.-i.1
Branzei, D.2
Hayashi, T.3
Suzuki, H.4
Masuko, T.5
Onoda, F.6
Heo, S.-J.7
Ikeda, H.8
Shimamoto, A.9
Furuichi, Y.10
Seki, M.11
Enomoto, T.12
-
97
-
-
0035902479
-
A yeast gene, MGS1, encoding a DNA-dependent AAA + ATPase is required to maintain genome stability
-
Hishida T., Iwasaki H., Ohno T., Morishita T., and Shinagawa H. A yeast gene, MGS1, encoding a DNA-dependent AAA + ATPase is required to maintain genome stability. Proc. Natl. Acad. Sci.V 98 (2001) 8283-8289
-
(2001)
Proc. Natl. Acad. Sci.V 98
, pp. 8283-8289
-
-
Hishida, T.1
Iwasaki, H.2
Ohno, T.3
Morishita, T.4
Shinagawa, H.5
-
98
-
-
0037090484
-
Saccharomyces cerevisiae MGS1 is essential in strains deficient in the RAD6-dependent DNA damage tolerance pathway
-
Hishida T., Ohno T., Iwasaki H., and Shinagawa H. Saccharomyces cerevisiae MGS1 is essential in strains deficient in the RAD6-dependent DNA damage tolerance pathway. EMBO J. 21 (2002) 2019-2029
-
(2002)
EMBO J.
, vol.21
, pp. 2019-2029
-
-
Hishida, T.1
Ohno, T.2
Iwasaki, H.3
Shinagawa, H.4
-
99
-
-
34548156750
-
Werner helicase-interacting protein 1 binds polyubiquitin via its zinc finger domain
-
Bish R.A., and Myers M.P. Werner helicase-interacting protein 1 binds polyubiquitin via its zinc finger domain. J. Biol. Chem. 282 (2007) 23184-23193
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 23184-23193
-
-
Bish, R.A.1
Myers, M.P.2
-
101
-
-
33745845186
-
Functional and physical interaction of yeast mgs1 with PCNA: impact on RAD6-dependent DNA damage tolerance
-
Hishida T., Ohya T., Kubota Y., Kamada Y., and Shinagawa H. Functional and physical interaction of yeast mgs1 with PCNA: impact on RAD6-dependent DNA damage tolerance. Mol. Cell. Biol. 26 (2006) 5509-5517
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 5509-5517
-
-
Hishida, T.1
Ohya, T.2
Kubota, Y.3
Kamada, Y.4
Shinagawa, H.5
-
102
-
-
0017746990
-
Bloom's syndrome: DNA replication in cultured fibroblasts and lymphocytes
-
Hand R., and German J. Bloom's syndrome: DNA replication in cultured fibroblasts and lymphocytes. Hum. Genet. 38 (1977) 297-306
-
(1977)
Hum. Genet.
, vol.38
, pp. 297-306
-
-
Hand, R.1
German, J.2
-
103
-
-
3142546346
-
A retarded rate of DNA chain growth in Bloom's syndrome
-
Hand R., and German J. A retarded rate of DNA chain growth in Bloom's syndrome. Proc. Natl. Acad. Sci. U.S.A. 72 (1975) 758-762
-
(1975)
Proc. Natl. Acad. Sci. U.S.A.
, vol.72
, pp. 758-762
-
-
Hand, R.1
German, J.2
-
104
-
-
34547132330
-
Endogenous {gamma}-H2AX-ATM-Chk2 checkpoint activation in bloom's syndrome helicase deficient cells is related to DNA replication arrested forks
-
Rao V.A., Conti C., Guirouilh-Barbat J., Nakamura A., Miao Z.-H., Davies S.L., Sacca B., Hickson I.D., Bensimon A., and Pommier Y. Endogenous {gamma}-H2AX-ATM-Chk2 checkpoint activation in bloom's syndrome helicase deficient cells is related to DNA replication arrested forks. Mol. Cancer Res. 5 (2007) 713-724
-
(2007)
Mol. Cancer Res.
, vol.5
, pp. 713-724
-
-
Rao, V.A.1
Conti, C.2
Guirouilh-Barbat, J.3
Nakamura, A.4
Miao, Z.-H.5
Davies, S.L.6
Sacca, B.7
Hickson, I.D.8
Bensimon, A.9
Pommier, Y.10
-
105
-
-
0033621354
-
The Werner syndrome gene product co-purifies with the DNA replication complex and interacts with pcna and topoisomerase i
-
Lebel M., Spillare E.A., Harris C.C., and Leder P. The Werner syndrome gene product co-purifies with the DNA replication complex and interacts with pcna and topoisomerase i. J. Biol. Chem. 274 (1999) 37795-37799
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37795-37799
-
-
Lebel, M.1
Spillare, E.A.2
Harris, C.C.3
Leder, P.4
-
106
-
-
0242694944
-
Werner protein stimulates topoisomerase I DNA relaxation activity
-
Laine J.-P., Opresko P.L., Indig F.E., Harrigan J.A., von Kobbe C., and Bohr V.A. Werner protein stimulates topoisomerase I DNA relaxation activity. Cancer Res. 63 (2003) 7136-7146
-
(2003)
Cancer Res.
, vol.63
, pp. 7136-7146
-
-
Laine, J.-P.1
Opresko, P.L.2
Indig, F.E.3
Harrigan, J.A.4
von Kobbe, C.5
Bohr, V.A.6
-
108
-
-
36249015877
-
The RecQ helicase-topoisomerase III-Rmi1 complex: a DNA structure-specific 'dissolvasome'?
-
Mankouri H.W., and Hickson I.D. The RecQ helicase-topoisomerase III-Rmi1 complex: a DNA structure-specific 'dissolvasome'?. Trends Biochem. Sci. 32 (2007) 538-546
-
(2007)
Trends Biochem. Sci.
, vol.32
, pp. 538-546
-
-
Mankouri, H.W.1
Hickson, I.D.2
-
109
-
-
36849029846
-
Novel pro- and anti-recombination activities of the Bloom's syndrome helicase
-
Bugreev D.V., Yu X., Egelman E.H., and Mazin A.V. Novel pro- and anti-recombination activities of the Bloom's syndrome helicase. Genes Dev. 21 (2007) 3085-3094
-
(2007)
Genes Dev.
, vol.21
, pp. 3085-3094
-
-
Bugreev, D.V.1
Yu, X.2
Egelman, E.H.3
Mazin, A.V.4
-
110
-
-
36849013079
-
RecQL5/RecQl5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments
-
Hu Y., Raynard S., Sehorn M.G., Lu X., Bussen W., Zheng L., Stark J.M., Barnes E.L., Chi P., Janscak P., Jasin M., Vogel H., Sung P., and Luo G. RecQL5/RecQl5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments. Genes Dev. 21 (2007) 3073-3084
-
(2007)
Genes Dev.
, vol.21
, pp. 3073-3084
-
-
Hu, Y.1
Raynard, S.2
Sehorn, M.G.3
Lu, X.4
Bussen, W.5
Zheng, L.6
Stark, J.M.7
Barnes, E.L.8
Chi, P.9
Janscak, P.10
Jasin, M.11
Vogel, H.12
Sung, P.13
Luo, G.14
-
111
-
-
0347987856
-
The Bloom's syndrome helicase suppresses crossing over during homologous recombination
-
Wu L., and Hickson I.D. The Bloom's syndrome helicase suppresses crossing over during homologous recombination. Nature 426 (2003) 870-874
-
(2003)
Nature
, vol.426
, pp. 870-874
-
-
Wu, L.1
Hickson, I.D.2
-
112
-
-
33645242115
-
BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates
-
Wu L., Bachrati C.Z., Ou J., Xu C., Yin J., Chang M., Wang W., Li L., Brown G.W., and Hickson I.D. BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates. Proc. Natl. Acad. Sci. 103 (2006) 4068-4073
-
(2006)
Proc. Natl. Acad. Sci.
, vol.103
, pp. 4068-4073
-
-
Wu, L.1
Bachrati, C.Z.2
Ou, J.3
Xu, C.4
Yin, J.5
Chang, M.6
Wang, W.7
Li, L.8
Brown, G.W.9
Hickson, I.D.10
-
113
-
-
34447115757
-
Role for BLM in replication-fork restart and suppression of origin firing after replicative stress
-
Epub 2007 Jun 2024
-
Davies S.L., North P.S., and Hickson I.D. Role for BLM in replication-fork restart and suppression of origin firing after replicative stress. Nat. Struct. Mol. Biol. 14 (2007) 677-679 Epub 2007 Jun 2024
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 677-679
-
-
Davies, S.L.1
North, P.S.2
Hickson, I.D.3
-
114
-
-
34547232986
-
Non-transcriptional control of DNA replication by c-Myc
-
Dominguez-Sola D., Ying C.Y., Grandori C., Ruggiero L., Chen B., Li M., Galloway D.A., Gu W., Gautier J., and Dalla-Favera R. Non-transcriptional control of DNA replication by c-Myc. Nature 448 (2007) 445-451
-
(2007)
Nature
, vol.448
, pp. 445-451
-
-
Dominguez-Sola, D.1
Ying, C.Y.2
Grandori, C.3
Ruggiero, L.4
Chen, B.5
Li, M.6
Galloway, D.A.7
Gu, W.8
Gautier, J.9
Dalla-Favera, R.10
-
115
-
-
0035169035
-
Werner's syndrome protein is required for correct recovery after replication arrest and DNA damage induced in S-phase of cell cycle
-
Pichierri P., Franchitto A., Mosesso P., and Palitti F. Werner's syndrome protein is required for correct recovery after replication arrest and DNA damage induced in S-phase of cell cycle. Mol. Biol. Cell 12 (2001) 2412-2421
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 2412-2421
-
-
Pichierri, P.1
Franchitto, A.2
Mosesso, P.3
Palitti, F.4
-
116
-
-
0016678691
-
Variegated translocation mosaicism in human skin fibroblast cultures
-
Hoehn H., Bryant E.M., Au K., Norwood T.H., Boman H., and Martin G.M. Variegated translocation mosaicism in human skin fibroblast cultures. Cytogenet. Cell Genet. 15 (1975) 282-298
-
(1975)
Cytogenet. Cell Genet.
, vol.15
, pp. 282-298
-
-
Hoehn, H.1
Bryant, E.M.2
Au, K.3
Norwood, T.H.4
Boman, H.5
Martin, G.M.6
-
117
-
-
13944255048
-
Werner syndrome protein and the MRE11 complex are involved in a common pathway of replication fork recovery
-
Epub 2004 Oct 1318
-
Franchitto A., and Pichierri P. Werner syndrome protein and the MRE11 complex are involved in a common pathway of replication fork recovery. Cell Cycle 3 (2004) 1331-1339 Epub 2004 Oct 1318
-
(2004)
Cell Cycle
, vol.3
, pp. 1331-1339
-
-
Franchitto, A.1
Pichierri, P.2
-
118
-
-
2442438604
-
Distinct functions for WRN and TP53 in a shared pathway of cellular response to 1-[beta]--arabinofuranosylcytosine and bleomycin
-
Poot M., Jin X., Hill J.P., Gollahon K.A., and Rabinovitch P.S. Distinct functions for WRN and TP53 in a shared pathway of cellular response to 1-[beta]--arabinofuranosylcytosine and bleomycin. Exp. Cell Res. 296 (2004) 327-336
-
(2004)
Exp. Cell Res.
, vol.296
, pp. 327-336
-
-
Poot, M.1
Jin, X.2
Hill, J.P.3
Gollahon, K.A.4
Rabinovitch, P.S.5
-
119
-
-
0033151822
-
Werner syndrome helicase contains a 5′-- > 3′ exonuclease activity that digests DNA and RNA strands in DNA/DNA and RNA/DNA duplexes dependent on unwinding
-
Suzuki N., Shiratori M., Goto M., and Furuichi Y. Werner syndrome helicase contains a 5′-- > 3′ exonuclease activity that digests DNA and RNA strands in DNA/DNA and RNA/DNA duplexes dependent on unwinding. Nucl. Acids Res. 27 (1999) 2361-2368
-
(1999)
Nucl. Acids Res.
, vol.27
, pp. 2361-2368
-
-
Suzuki, N.1
Shiratori, M.2
Goto, M.3
Furuichi, Y.4
|