-
1
-
-
0013907774
-
Werner syndrome: A review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process
-
Epstein C.J., Martin G.M., Schultz A.L., Motulsky A.G. Werner syndrome: a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process. Medicine. 45:1966;177-221
-
(1966)
Medicine
, vol.45
, pp. 177-221
-
-
Epstein, C.J.1
Martin, G.M.2
Schultz, A.L.3
Motulsky, A.G.4
-
2
-
-
0020306698
-
Prolongation of S phase and whole cell cycle in Werner's syndrome fibroblasts
-
Takeuchi F., Hanaoka F., Goto M., Yamada M.-A., Miyamoto T. Prolongation of S phase and whole cell cycle in Werner's syndrome fibroblasts. Exp. Gerontol. 17:1982;473-480
-
(1982)
Exp. Gerontol.
, vol.17
, pp. 473-480
-
-
Takeuchi, F.1
Hanaoka, F.2
Goto, M.3
Yamada, M.-A.4
Miyamoto, T.5
-
3
-
-
0026702210
-
Impaired S-phase transit of Werner syndrome cells expressed in lymphoblastoid cell lines
-
Poot M., Hoehn H., Rünger T.M., Martin G.M. Impaired S-phase transit of Werner syndrome cells expressed in lymphoblastoid cell lines. Exp. Cell Res. 202:1992;267-273
-
(1992)
Exp. Cell Res.
, vol.202
, pp. 267-273
-
-
Poot, M.1
Hoehn, H.2
Rünger, T.M.3
Martin, G.M.4
-
4
-
-
0016678691
-
Variegated translocation mosaicism in human skin fibroblast cultures
-
Hoehn H., Bryant E.M., Au K., Norwood T.H., Boman H., Martin G.M. Variegated translocation mosaicism in human skin fibroblast cultures. Cytogenet. Cell Genet. 15:1975;282-298
-
(1975)
Cytogenet. Cell Genet.
, vol.15
, pp. 282-298
-
-
Hoehn, H.1
Bryant, E.M.2
Au, K.3
Norwood, T.H.4
Boman, H.5
Martin, G.M.6
-
5
-
-
0024465870
-
Mutator phenotype of Werner syndrome is characterized by extensive deletions
-
Fukuchi K., Martin G.M., Monnat R.J. Jr. Mutator phenotype of Werner syndrome is characterized by extensive deletions. Proc. Natl. Acad. Sci. U. S. A. 86:1989;5893-5897
-
(1989)
Proc. Natl. Acad. Sci. U. S. A.
, vol.86
, pp. 5893-5897
-
-
Fukuchi, K.1
Martin, G.M.2
Monnat Jr., R.J.3
-
6
-
-
0014816132
-
Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype
-
Martin G.M., Sprague C.A., Epstein C.J. Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype. Lab. Invest. 23:1970;86-92
-
(1970)
Lab. Invest.
, vol.23
, pp. 86-92
-
-
Martin, G.M.1
Sprague, C.A.2
Epstein, C.J.3
-
7
-
-
0028078910
-
Hypermutable ligation of plasmid DNA ends in cells from patients with Werner syndrome
-
Rünger T.M., Bauer C., Dekant B., Möller K., Sobotta P., Czerny C., Poot M., Martin G.M. Hypermutable ligation of plasmid DNA ends in cells from patients with Werner syndrome. J. Invest. Dermatol. 102:1994;45-48
-
(1994)
J. Invest. Dermatol.
, vol.102
, pp. 45-48
-
-
Rünger, T.M.1
Bauer, C.2
Dekant, B.3
Möller, K.4
Sobotta, P.5
Czerny, C.6
Poot, M.7
Martin, G.M.8
-
8
-
-
0035871341
-
Loss of Werner syndrome protein function promotes aberrant mitotic recombination
-
Prince P.R., Emond M.J., Monnat R.J. Jr. Loss of Werner syndrome protein function promotes aberrant mitotic recombination. Genes Dev. 15:2001;933-938
-
(2001)
Genes Dev.
, vol.15
, pp. 933-938
-
-
Prince, P.R.1
Emond, M.J.2
Monnat Jr., R.J.3
-
9
-
-
15844409553
-
Positional cloning of the Werner's syndrome gene
-
Yu C.E., Oshima J., Fu Y.H., Wijsman E.M., Hisama F., Alisch R., Matthews S., Nakura J., Miki T., Ouais S., Martin G.M., Mulligan J., Schellenberg G.D. Positional cloning of the Werner's syndrome gene. Science. 272:1996;258-262
-
(1996)
Science
, vol.272
, pp. 258-262
-
-
Yu, C.E.1
Oshima, J.2
Fu, Y.H.3
Wijsman, E.M.4
Hisama, F.5
Alisch, R.6
Matthews, S.7
Nakura, J.8
Miki, T.9
Ouais, S.10
Martin, G.M.11
Mulligan, J.12
Schellenberg, G.D.13
-
10
-
-
0031204917
-
Impaired nuclear localization of defective DNA helicases in Werner's syndrome
-
Matsumoto T., Shimamoto A., Goto M., Furuichi Y. Impaired nuclear localization of defective DNA helicases in Werner's syndrome. Nat. Genet. 16:1997;335-356
-
(1997)
Nat. Genet.
, vol.16
, pp. 335-356
-
-
Matsumoto, T.1
Shimamoto, A.2
Goto, M.3
Furuichi, Y.4
-
11
-
-
0030751354
-
The Werner syndrome protein is a DNA helicase
-
Gray M.D., Shen J.C., Kamath-Loeb A.S., Blank A., Sopher B.L., Martin G.M., Oshima J., Loeb L.A. The Werner syndrome protein is a DNA helicase. Nat. Genet. 17:1997;100-103
-
(1997)
Nat. Genet.
, vol.17
, pp. 100-103
-
-
Gray, M.D.1
Shen, J.C.2
Kamath-Loeb, A.S.3
Blank, A.4
Sopher, B.L.5
Martin, G.M.6
Oshima, J.7
Loeb, L.A.8
-
12
-
-
0032545423
-
Werner syndrome protein. II. Characterization of the integral 3′→5′ DNA exonuclease
-
Kamath-Loeb A.S., Shen J.-C., Loeb L.A., Fry M. Werner syndrome protein. II. Characterization of the integral 3′→5′ DNA exonuclease. J. Biol. Chem. 273:1998;34145-34150
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 34145-34150
-
-
Kamath-Loeb, A.S.1
Shen, J.-C.2
Loeb, L.A.3
Fry, M.4
-
13
-
-
0032526583
-
Characterization of Werner syndrome protein DNA helicase activity: Directionality, substrate dependence and stimulation by replication protein a
-
Shen J.C., Gray M.D., Oshima J., Loeb L.A. Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A. Nucleic Acids Res. 26:1998;2879-2885
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 2879-2885
-
-
Shen, J.C.1
Gray, M.D.2
Oshima, J.3
Loeb, L.A.4
-
14
-
-
0343091571
-
Potent inhibition of Werner and Bloom helicases by DNA minor groove binding drugs
-
Brosh R.M. Jr., Karow J.K., White E.J., Shaw N.D., Hickson I.D., Bohr V.A. Potent inhibition of Werner and Bloom helicases by DNA minor groove binding drugs. Nucleic Acids Res. 28:2000;2420-2430
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 2420-2430
-
-
Brosh Jr., R.M.1
Karow, J.K.2
White, E.J.3
Shaw, N.D.4
Hickson, I.D.5
Bohr, V.A.6
-
15
-
-
0034283889
-
Werner syndrome exonuclease catalyzes structure-dependent degradation of DNA
-
Shen J.-C., Loeb L.A. Werner syndrome exonuclease catalyzes structure-dependent degradation of DNA. Nucleic Acids Res. 28:2000;3260-3268
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 3260-3268
-
-
Shen, J.-C.1
Loeb, L.A.2
-
16
-
-
0347362703
-
Werner syndrome protein contains three structure-specific DNA binding domains
-
von Kobbe C., Thoma N.H., Czyzewski B.K., Pavletich N.P., Bohr V.A. Werner syndrome protein contains three structure-specific DNA binding domains. J. Biol. Chem. 278:2003;52997-53006
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 52997-53006
-
-
Von Kobbe, C.1
Thoma, N.H.2
Czyzewski, B.K.3
Pavletich, N.P.4
Bohr, V.A.5
-
17
-
-
0023712434
-
Spontaneous and induced chromosomal instability in Werner syndrome
-
Gebhardt E., Bauer R., Raub U., Schinzel M., Reuprecht K.W., Jonas J.B. Spontaneous and induced chromosomal instability in Werner syndrome. Hum. Genet. 80:1988;135-139
-
(1988)
Hum. Genet.
, vol.80
, pp. 135-139
-
-
Gebhardt, E.1
Bauer, R.2
Raub, U.3
Schinzel, M.4
Reuprecht, K.W.5
Jonas, J.B.6
-
18
-
-
0031453968
-
An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild type and homozygous mutants
-
Ogburn C.E., Oshima J., Poot M., Chen R., Hunt K.E., Gollahon K.A., Rabinovitch P.S., Martin G.M. An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild type and homozygous mutants. Hum. Genet. 101:1997;121-125
-
(1997)
Hum. Genet.
, vol.101
, pp. 121-125
-
-
Ogburn, C.E.1
Oshima, J.2
Poot, M.3
Chen, R.4
Hunt, K.E.5
Gollahon, K.A.6
Rabinovitch, P.S.7
Martin, G.M.8
-
19
-
-
0001225459
-
Differential effects of cytotoxic drugs on mortal and immortalized B-lymphoblastoid cell lines from normal and Werner's syndrome patients
-
Okada M., Goto M., Furuichi Y., Sugimoto M. Differential effects of cytotoxic drugs on mortal and immortalized B-lymphoblastoid cell lines from normal and Werner's syndrome patients. Biol. Pharm. Bull. 21:1998;235-239
-
(1998)
Biol. Pharm. Bull.
, vol.21
, pp. 235-239
-
-
Okada, M.1
Goto, M.2
Furuichi, Y.3
Sugimoto, M.4
-
20
-
-
0033010781
-
Werner syndrome lymphoblastoid cells are sensitive to camptothecin-induced apoptosis in S-phase
-
Poot M., Gollahon K.A., Rabinovitch P.S. Werner syndrome lymphoblastoid cells are sensitive to camptothecin-induced apoptosis in S-phase. Hum. Genet. 104:1999;10-14
-
(1999)
Hum. Genet.
, vol.104
, pp. 10-14
-
-
Poot, M.1
Gollahon, K.A.2
Rabinovitch, P.S.3
-
21
-
-
0035349905
-
Werner syndrome cells are sensitive to DNA cross-linking drugs
-
Poot M., Yom J.S., Whang S.H., Kato J.T., Gollahon K.A., Rabinovitch P.S. Werner syndrome cells are sensitive to DNA cross-linking drugs. FASEB J. 15:2001;1224-1226
-
(2001)
FASEB J.
, vol.15
, pp. 1224-1226
-
-
Poot, M.1
Yom, J.S.2
Whang, S.H.3
Kato, J.T.4
Gollahon, K.A.5
Rabinovitch, P.S.6
-
22
-
-
0036581178
-
Werner syndrome diploid fibroblasts are sensitive to 4-nitroquinoline-N- oxide and 8-methoxypsoralen: Implications for the disease phenotype
-
Poot M., Gollahon K.A., Emond M.J., Silber J.R., Rabinovitch P.S. Werner syndrome diploid fibroblasts are sensitive to 4-nitroquinoline-N-oxide and 8-methoxypsoralen: implications for the disease phenotype. FASEB J. 16:2002;757-758
-
(2002)
FASEB J.
, vol.16
, pp. 757-758
-
-
Poot, M.1
Gollahon, K.A.2
Emond, M.J.3
Silber, J.R.4
Rabinovitch, P.S.5
-
23
-
-
0025827884
-
Cytostatic synergism between bromodeoxyuridine, bleomycin, cisplatin and chlorambucil demonstrated by a sensitive cell kinetic assay
-
Poot M., Schuster A., Hoehn H. Cytostatic synergism between bromodeoxyuridine, bleomycin, cisplatin and chlorambucil demonstrated by a sensitive cell kinetic assay. Biochem. Pharmacol. 41:1991;1903-1909
-
(1991)
Biochem. Pharmacol.
, vol.41
, pp. 1903-1909
-
-
Poot, M.1
Schuster, A.2
Hoehn, H.3
-
25
-
-
0034612585
-
Substrate specificity of the p53-associated 3′-5′ exonuclease
-
Skalski V., Lin Z.Y., Choi B.Y., Brown K.R. Substrate specificity of the p53-associated 3′-5′ exonuclease. Oncogene. 19:2000;3321-3329
-
(2000)
Oncogene
, vol.19
, pp. 3321-3329
-
-
Skalski, V.1
Lin, Z.Y.2
Choi, B.Y.3
Brown, K.R.4
-
26
-
-
0033019052
-
Different regulation of the p53 core domain activities 3′-to-5′ exonuclease and sequence-specific DNA binding
-
Janus F., Albrechtsen N., Knippschild U., Wiesmuller L., Grosse F., Deppert W. Different regulation of the p53 core domain activities 3′-to-5′ exonuclease and sequence-specific DNA binding. Mol. Cell. Biol. 19:1999;2155-2168
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 2155-2168
-
-
Janus, F.1
Albrechtsen, N.2
Knippschild, U.3
Wiesmuller, L.4
Grosse, F.5
Deppert, W.6
-
27
-
-
0032832195
-
Physical and functional interaction between p53 and the Werner's syndrome protein
-
Blander G., Kipnis J., Leal J.F., Yu C.E., Schellenberg G.D., Oren M. Physical and functional interaction between p53 and the Werner's syndrome protein. J. Biol. Chem. 274:1999;29463-29469
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 29463-29469
-
-
Blander, G.1
Kipnis, J.2
Leal, J.F.3
Yu, C.E.4
Schellenberg, G.D.5
Oren, M.6
-
28
-
-
0035860775
-
P53 modulates the exonuclease activity of Werner syndrome protein
-
Brosh R.M. Jr., Karmakar P., Sommers J.A., Yang Q., Wang X.W., Spillare E.A., Harris C.C., Bohr V.A. p53 modulates the exonuclease activity of Werner syndrome protein. J. Biol. Chem. 276:2001;35093-35102
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35093-35102
-
-
Brosh Jr., R.M.1
Karmakar, P.2
Sommers, J.A.3
Yang, Q.4
Wang, X.W.5
Spillare, E.A.6
Harris, C.C.7
Bohr, V.A.8
-
29
-
-
0001606206
-
Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells
-
Wolf D., Rotter V. Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells. Proc. Natl. Acad. Sci. U. S. A. 82:1985;790-794
-
(1985)
Proc. Natl. Acad. Sci. U. S. A.
, vol.82
, pp. 790-794
-
-
Wolf, D.1
Rotter, V.2
-
30
-
-
0027261147
-
The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents
-
Gorczyca W., Gong J., Ardelt B., Traganos F., Darzynkiewicz Z. The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents. Cancer Res. 53:1993;3186-3192
-
(1993)
Cancer Res.
, vol.53
, pp. 3186-3192
-
-
Gorczyca, W.1
Gong, J.2
Ardelt, B.3
Traganos, F.4
Darzynkiewicz, Z.5
-
31
-
-
0030930925
-
Increase of spontaneous intrachromosomal homologous recombination in mammalian cells expressing a mutant p53 protein
-
Bertrand P., Rouillard D., Boulet A., Levalois C., Soussi T., Lopez B.S. Increase of spontaneous intrachromosomal homologous recombination in mammalian cells expressing a mutant p53 protein. Oncogene. 14:1997;1117-1122
-
(1997)
Oncogene
, vol.14
, pp. 1117-1122
-
-
Bertrand, P.1
Rouillard, D.2
Boulet, A.3
Levalois, C.4
Soussi, T.5
Lopez, B.S.6
-
32
-
-
0014587529
-
Soft-tissue sarcomas, breast cancer, and other neoplasms: A familial syndrome?
-
Li F.P., Fraumeni J.F. Jr. Soft-tissue sarcomas, breast cancer, and other neoplasms: a familial syndrome? Ann. Intern. Med. 71:1969;747-752
-
(1969)
Ann. Intern. Med.
, vol.71
, pp. 747-752
-
-
Li, F.P.1
Fraumeni Jr., J.F.2
-
33
-
-
0030957152
-
Li-Fraumeni syndrome: A molecular and clinical review
-
Varley J.M., Evans D.G.R., Birch J.M. Li-Fraumeni syndrome: a molecular and clinical review. Br. J. Cancer. 76:1997;1-14
-
(1997)
Br. J. Cancer
, vol.76
, pp. 1-14
-
-
Varley, J.M.1
Evans, D.G.R.2
Birch, J.M.3
-
34
-
-
17544402913
-
Mutations in WRN gene in mice accelerate mortality in a p53-null background
-
Lombard D.B., Beard C., Johnson B., Marciniak R.A., Dausman J., Bronson R., Buhlman J.E., Lipman R., Curry R., Sharpe A., Jaenish R., Guarente L. Mutations in WRN gene in mice accelerate mortality in a p53-null background. Mol. Cell. Biol. 20:2000;3286-3291
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 3286-3291
-
-
Lombard, D.B.1
Beard, C.2
Johnson, B.3
Marciniak, R.A.4
Dausman, J.5
Bronson, R.6
Buhlman, J.E.7
Lipman, R.8
Curry, R.9
Sharpe, A.10
Jaenish, R.11
Guarente, L.12
-
35
-
-
0035266463
-
Tumorigenic effect of nonfunctional p53 and p21 in mice mutant in the Werner syndrome helicase
-
Lebel M., Cardiff R.D., Leder P. Tumorigenic effect of nonfunctional p53 and p21 in mice mutant in the Werner syndrome helicase. Cancer Res. 61:2001;1816-1819
-
(2001)
Cancer Res.
, vol.61
, pp. 1816-1819
-
-
Lebel, M.1
Cardiff, R.D.2
Leder, P.3
-
36
-
-
0024396338
-
Structure of bleomycin-induced DNA double-strand breaks: Predominance of blunt ends and single-base 5′ extensions
-
Povirk L.F., Han Y.H., Steighner R.J. Structure of bleomycin-induced DNA double-strand breaks: predominance of blunt ends and single-base 5′ extensions. Biochemistry. 28:1989;5808-5814
-
(1989)
Biochemistry
, vol.28
, pp. 5808-5814
-
-
Povirk, L.F.1
Han, Y.H.2
Steighner, R.J.3
-
37
-
-
0028861937
-
P53-independent death and p53-induced protection against apoptosis in fibroblasts treated with chemotherapeutic drugs
-
Malcomson R.D., Oren M., Wyllie A.H., Harrison D.J. p53-independent death and p53-induced protection against apoptosis in fibroblasts treated with chemotherapeutic drugs. Br. J. Cancer. 72:1995;952-957
-
(1995)
Br. J. Cancer
, vol.72
, pp. 952-957
-
-
Malcomson, R.D.1
Oren, M.2
Wyllie, A.H.3
Harrison, D.J.4
-
38
-
-
0018348655
-
T antigen is bound to a host protein in SV40-transformed cells
-
Lane D.P., Crawford L.V. T antigen is bound to a host protein in SV40-transformed cells. Nature. 278:1979;261-263
-
(1979)
Nature
, vol.278
, pp. 261-263
-
-
Lane, D.P.1
Crawford, L.V.2
-
39
-
-
0034650238
-
WRN helicase expression in Werner syndrome cell lines
-
Moser M.J., Kamath-Loeb A.S., Jacob J.E., Bennett S.E., Oshima J., Monnat R.J. Jr. WRN helicase expression in Werner syndrome cell lines. Nucleic Acids Res. 28:2000;648-654
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 648-654
-
-
Moser, M.J.1
Kamath-Loeb, A.S.2
Jacob, J.E.3
Bennett, S.E.4
Oshima, J.5
Monnat Jr., R.J.6
-
40
-
-
0028990145
-
Absence of radiation-induced G1 arrest in two closely related human lymphoblastoid cell lines that differ in p53 status
-
Little J.B., Nagasawa H., Keng P.C., Yu Y., Li C.-Y. Absence of radiation-induced G1 arrest in two closely related human lymphoblastoid cell lines that differ in p53 status. J. Biol. Chem. 270:1995;11033-11036
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 11033-11036
-
-
Little, J.B.1
Nagasawa, H.2
Keng, P.C.3
Yu, Y.4
Li, C.-Y.5
-
41
-
-
0030889455
-
Detection of apoptosis in live cells by MitoTracker Red CMXRos and SYTO dye flow cytometry
-
Poot M., Gibson L.L., Singer V.L. Detection of apoptosis in live cells by MitoTracker Red CMXRos and SYTO dye flow cytometry. Cytometry. 27:1997;358-364
-
(1997)
Cytometry
, vol.27
, pp. 358-364
-
-
Poot, M.1
Gibson, L.L.2
Singer, V.L.3
-
42
-
-
0023841617
-
BrdU-Hoechst flow cytometry: A unique tool for quantitative cell cycle analysis
-
Rabinovitch P.S., Kubbies M., Chen Y.C., Schindler D., Hoehn H. BrdU-Hoechst flow cytometry: a unique tool for quantitative cell cycle analysis. Exp. Cell Res. 174:1988;309-318
-
(1988)
Exp. Cell Res.
, vol.174
, pp. 309-318
-
-
Rabinovitch, P.S.1
Kubbies, M.2
Chen, Y.C.3
Schindler, D.4
Hoehn, H.5
-
43
-
-
0036569897
-
A novel flow cytometric technique for drug cytotoxicity gives results comparable to colony-forming assays
-
Poot M., Silber J.R., Rabinovitch P.S. A novel flow cytometric technique for drug cytotoxicity gives results comparable to colony-forming assays. Cytometry. 48:2002;1-5
-
(2002)
Cytometry
, vol.48
, pp. 1-5
-
-
Poot, M.1
Silber, J.R.2
Rabinovitch, P.S.3
-
44
-
-
0019032544
-
A model for the computer analysis of synchronous DNA distributions by flow cytometry
-
Fox M.H. A model for the computer analysis of synchronous DNA distributions by flow cytometry. Cytometry. 1:1980;71-77
-
(1980)
Cytometry
, vol.1
, pp. 71-77
-
-
Fox, M.H.1
-
45
-
-
0034800217
-
Effects of p53 mutations on cellular sensitivity to ionizing radiation
-
Matsui Y., Tsuchida Y., Keng P.C. Effects of p53 mutations on cellular sensitivity to ionizing radiation. Am. J. Clin. Oncol. 24:2001;486-490
-
(2001)
Am. J. Clin. Oncol.
, vol.24
, pp. 486-490
-
-
Matsui, Y.1
Tsuchida, Y.2
Keng, P.C.3
-
46
-
-
0024533270
-
The cloned human DNA excision repair gene ERCC-1 fails to correct xeroderma pigmentosum complementation groups a through I
-
van Duin M., Vredeveldt G., Mayne L.V., Odijk H., Vermeulen W., Klein B., Weeda G., Hoeijmakers J.H., Westerveld A. The cloned human DNA excision repair gene ERCC-1 fails to correct xeroderma pigmentosum complementation groups A through I. Mutat. Res. 217:1989;83-92
-
(1989)
Mutat. Res.
, vol.217
, pp. 83-92
-
-
Van Duin, M.1
Vredeveldt, G.2
Mayne, L.V.3
Odijk, H.4
Vermeulen, W.5
Klein, B.6
Weeda, G.7
Hoeijmakers, J.H.8
Westerveld, A.9
-
47
-
-
0021082297
-
Mutagenesis and lethality following S phase irradiation of xeroderma pigmentosum and normal human diploid fibroblasts with ultraviolet light
-
Grosovsky A.J., Little J.B. Mutagenesis and lethality following S phase irradiation of xeroderma pigmentosum and normal human diploid fibroblasts with ultraviolet light. Carcinogenesis. 4:1983;1389-1393
-
(1983)
Carcinogenesis
, vol.4
, pp. 1389-1393
-
-
Grosovsky, A.J.1
Little, J.B.2
-
48
-
-
0037173717
-
SV40 large T-antigen disturbs the formation of nuclear DNA-repair foci containing MRE11
-
Digweed M., Demuth I., Rothe S., Scholz R., Jordan A., Grotzinger C., Schindler D., Grompe M., Sperling K. SV40 large T-antigen disturbs the formation of nuclear DNA-repair foci containing MRE11. Oncogene. 21:2002;4873-4878
-
(2002)
Oncogene
, vol.21
, pp. 4873-4878
-
-
Digweed, M.1
Demuth, I.2
Rothe, S.3
Scholz, R.4
Jordan, A.5
Grotzinger, C.6
Schindler, D.7
Grompe, M.8
Sperling, K.9
-
49
-
-
0037416149
-
BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination
-
Sengupta S., Linke S.P., Pedeux R., Yang Q., Farnsworth J., Garfield S.H., Valerie K., Shay J.W., Ellis N.A., Wasylyk B., Harris C.C. BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination. EMBO J. 22:2003;1210-1222
-
(2003)
EMBO J.
, vol.22
, pp. 1210-1222
-
-
Sengupta, S.1
Linke, S.P.2
Pedeux, R.3
Yang, Q.4
Farnsworth, J.5
Garfield, S.H.6
Valerie, K.7
Shay, J.W.8
Ellis, N.A.9
Wasylyk, B.10
Harris, C.C.11
-
50
-
-
18544377842
-
The processing of Holliday junctions by BLM and WRN helicases is regulated by p53
-
Yang Q., Zhang R., Wang X.W., Spillare E.A., Linke S.P., Subramanian D., Griffith J.D., Li J.L., Hickson I.D., Shen J.C., Loeb L.A., Mazur S.J., Appella E., Brosh R.M. Jr., Karmakar P., Bohr V.A., Harris C.C. The processing of Holliday junctions by BLM and WRN helicases is regulated by p53. J. Biol. Chem. 277:2002;31980-31987
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 31980-31987
-
-
Yang, Q.1
Zhang, R.2
Wang, X.W.3
Spillare, E.A.4
Linke, S.P.5
Subramanian, D.6
Griffith, J.D.7
Li, J.L.8
Hickson, I.D.9
Shen, J.C.10
Loeb, L.A.11
Mazur, S.J.12
Appella, E.13
Brosh Jr., R.M.14
Karmakar, P.15
Bohr, V.A.16
Harris, C.C.17
-
51
-
-
0036787870
-
Homologous recombination resolution defect in Werner syndrome
-
Saintigny Y., Makienko K., Swanson C., Emond M.J., Monnat R.J. Jr. Homologous recombination resolution defect in Werner syndrome. Mol. Cell. Biol. 22:2002;6971-6978
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 6971-6978
-
-
Saintigny, Y.1
Makienko, K.2
Swanson, C.3
Emond, M.J.4
Monnat Jr., R.J.5
-
52
-
-
0035093737
-
DNA double-strand breaks: Signaling, repair and the cancer connection
-
Khanna K.K., Jackson S.P. DNA double-strand breaks: signaling, repair and the cancer connection. Nat. Genet. 27:2001;247-254
-
(2001)
Nat. Genet.
, vol.27
, pp. 247-254
-
-
Khanna, K.K.1
Jackson, S.P.2
-
53
-
-
0033621392
-
Substrate specificities and identification of putative substrates of ATM kinase family members
-
Kim S.T., Lim D.S., Canman C.E., Kastan M.B. Substrate specificities and identification of putative substrates of ATM kinase family members. J. Biol. Chem. 274:1999;37538-37543
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37538-37543
-
-
Kim, S.T.1
Lim, D.S.2
Canman, C.E.3
Kastan, M.B.4
-
54
-
-
0037435026
-
Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle
-
Pichierri P., Rosselli F., Franchitto A. Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle. Oncogene. 22:2003;1491-1500
-
(2003)
Oncogene
, vol.22
, pp. 1491-1500
-
-
Pichierri, P.1
Rosselli, F.2
Franchitto, A.3
-
55
-
-
0033517779
-
Lack of dependence on p53 for DNA double strand break repair of episomal vectors in human lymphoblasts
-
Kohli M., Jorgensen T.J. Lack of dependence on p53 for DNA double strand break repair of episomal vectors in human lymphoblasts. Biochem. Biophys. Res. Commun. 264:1999;702-708
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.264
, pp. 702-708
-
-
Kohli, M.1
Jorgensen, T.J.2
-
56
-
-
0033199454
-
Enzymatic and DNA binding properties of purified WRN protein: High affinity binding to single-stranded DNA but not to DNA damage induced by 4NQO
-
Orren D.K., Brosh R.M. Jr., Nehlin J.O., Machwe A., Gray M.D., Bohr V.A. Enzymatic and DNA binding properties of purified WRN protein: high affinity binding to single-stranded DNA but not to DNA damage induced by 4NQO. Nucleic Acids Res. 27:1999;3557-3566
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 3557-3566
-
-
Orren, D.K.1
Brosh Jr., R.M.2
Nehlin, J.O.3
MacHwe, A.4
Gray, M.D.5
Bohr, V.A.6
-
57
-
-
0242694944
-
Werner protein stimulates topoisomerase I DNA relaxation activity
-
Laine J.P., Opresko P.L., Indig F.E., Harrigan J.A., von Kobbe C., Bohr V.A. Werner protein stimulates topoisomerase I DNA relaxation activity. Cancer Res. 63:2003;7136-7146
-
(2003)
Cancer Res.
, vol.63
, pp. 7136-7146
-
-
Laine, J.P.1
Opresko, P.L.2
Indig, F.E.3
Harrigan, J.A.4
Von Kobbe, C.5
Bohr, V.A.6
-
58
-
-
0242721664
-
Central role for the Werner syndrome protein/poly(ADP-ribose) polymerase 1 complex in the poly(ADP-ribosyl)ation pathway after DNA damage
-
von Kobbe C., Harrigan J.A., May A., Opresko P.L., Dawut L., Cheng W.H., Bohr V.A. Central role for the Werner syndrome protein/poly(ADP-ribose) polymerase 1 complex in the poly(ADP-ribosyl)ation pathway after DNA damage. Mol. Cell. Biol. 23:2003;8601-8613
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 8601-8613
-
-
Von Kobbe, C.1
Harrigan, J.A.2
May, A.3
Opresko, P.L.4
Dawut, L.5
Cheng, W.H.6
Bohr, V.A.7
|