Sumoylation of PCNA: Wrestling with recombination at stalled replication forks

DNA Repair

Volumn 5, Issue 3, 2006, Pages 399-403

  Watts, Felicity Z ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

Post replication repair; Rad51; Recombination; Srs2; Ubiquitin

Indexed keywords

CYCLINE; DNA POLYMERASE; NUCLEIC ACID BINDING PROTEIN; PROTEIN RAD6; SUMO PROTEIN; UNCLASSIFIED DRUG;

DNA RECOMBINATION; DNA REPAIR; DNA REPLICATION; EUKARYOTE; GENE CONTROL; GENE FUNCTION; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; REVIEW; SACCHAROMYCES CEREVISIAE;

EUKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 32644454570     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2005.11.002     Document Type: Article

References (28)

1. C. Hoege, B. Pfander, G.L. Moldovan, G. Pyrowolakis, and S. Jentsch RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO Nature 419 2002 135 141
2. P. Stelter, and H.D. Ulrich Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation Nature 425 2003 188 191
3. B. Pfander, G.L. Moldovan, M. Sacher, C. Hoege, and S. Jentsch SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase Nature 436 2005 428 433
4. E. Papouli, S. Chen, A.A. Davies, D. Huttner, L. Krejci, P. Sung, and H.D. Ulrich Crosstalk between SUMO and ubiquitin on PCNA is mediated by recruitment of the helicase Srs2p Mol. Cell. 19 2005 123 133
5. R.M. Hofmann, and C.M. Pickart Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair Cell 96 1999 645 653
6. V. Bailly, J. Lamb, P. Sung, S. Prakash, and L. Prakash Specific complex formation between yeast RAD6 and RAD18 proteins: a potential mechanism for targeting RAD6 ubiquitin-conjugating activity to DNA damage sites Genes Dev. 8 1994 811 820
7. H.D. Ulrich, and S. Jentsch Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair EMBO J. 19 2000 3388 3397
8. G.A. Bauer, and P.M. Burgers Molecular cloning, structure and expression of the yeast proliferating cell nuclear antigen gene Nucleic Acids Res. 18 1990 261 265
9. R.E. Johnson, S. Prakash, and L. Prakash Requirement of DNA polymerase activity of yeast Rad30 protein for its biological function J. Biol. Chem. 274 1999 15975 15977
10. J.R. Nelson, C.W. Lawrence, and D.C. Hinkle Thymine-thymine dimer bypass by yeast DNA polymerase zeta Science 272 1996 1646 1649
11. C.M. Pickart, and D. Fushman Polyubiquitin chains: polymeric protein signals Curr. Opin. Chem. Biol. 8 2004 610 616
12. T. Kamitani, K. Kito, H.P. Nguyen, H. Wada, T. Fukuda-Kamitani, and E.T. Yeh Identification of three major sentrinization sites in PML J. Biol. Chem. 273 1998 26675 26682
13. E.S. Johnson, and A.A. Gupta An E3-like factor that promotes SUMO conjugation to the yeast septins Cell 106 2001 735 744
14. R.T. Hay SUMO: a history of modification Mol. Cell. 18 2005 1 12
15. J.M. Desterro, M.S. Rodriguez, and R.T. Hay SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation Mol. Cell. 2 1998 233 239
16. G. Maga, and U. Hubscher Proliferating cell nuclear antigen (PCNA): a dancer with many partners J. Cell. Sci. 116 2003 3051 3060
17. E. Warbrick The puzzle of PCNA's many partners Bioessays 22 2000 997 1006
18. C.W. Lawrence, and R.B. Christensen Metabolic suppressors of trimethoprim and ultraviolet light sensitivities of Saccharomyces cerevisiae rad6 mutants J. Bacteriol. 139 1979 866 876
19. L. Krejci, S. Van Komen, Y. Li, J. Villemain, M.S. Reddy, H. Klein, T. Ellenberger, and P. Sung DNA helicase Srs2 disrupts the Rad51 presynaptic filament Nature 423 2003 305 309
20. X. Veaute, J. Jeusset, C. Soustelle, S.C. Kowalczykowski, E. Le Cam, and F. Fabre The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments Nature 423 2003 309 312
21. R.H. Schiestl, S. Prakash, and L. Prakash The SRS2 suppressor of rad6 mutations of Saccharomyces cerevisiae acts by channeling DNA lesions into the RAD52 DNA repair pathway Genetics 124 1990 817 831
22. P.L. Kannouche, J. Wing, and A.R. Lehmann Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage Mol. Cell. 14 2004 491 500
23. P. Reynolds, M.H. Koken, J.H. Hoeijmakers, S. Prakash, and L. Prakash The rhp6+ gene of Schizosaccharomyces pombe: a structural and functional homolog of the RAD6 gene from the distantly related yeast Saccharomyces cerevisiae EMBO J. 9 1990 1423 1430
24. C.L. Doe, and M.C. Whitby The involvement of Srs2 in post-replication repair and homologous recombination in fission yeast Nucleic Acids Res. 32 2004 1480 1491
25. I.D. Hickson RecQ helicases: caretakers of the genome Nat. Rev. Cancer 3 2003 169 178
26. T. Morishita, F. Furukawa, C. Sakaguchi, T. Toda, A.M. Carr, H. Iwasaki, and H. Shinagawa Role of the Schizosaccharomyces pombe F-Box DNA helicase in processing recombination intermediates Mol. Cell. Biol. 25 2005 8074 8083
27. F. Osman, J. Dixon, A.R. Barr, and M.C. Whitby The F-Box DNA helicase Fbh1 prevents Rhp51-dependent recombination without mediator proteins Mol. Cell. Biol. 25 2005 8084 8096
28. J.M. Murray, H.D. Lindsay, C.A. Munday, and A.M. Carr Role of Schizosaccharomyces pombe RecQ homolog, recombination, and checkpoint genes in UV damage tolerance Mol. Cell. Biol. 17 1997 6868 6875