메뉴 건너뛰기




Volumn 13, Issue 14, 2008, Pages 5387-5405

Apolipoprotein e may be a critical factor in hormone therapy neuroprotection

Author keywords

Apolipoprotein E; Hormone replacement; Menopause; Neuroprotection; Review

Indexed keywords

MUS;

EID: 52049120567     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/3088     Document Type: Review
Times cited : (24)

References (223)
  • 2
    • 26844491712 scopus 로고    scopus 로고
    • Medroxyprogesterone acetate induces cell proliferation through up-regulation of cyclin D1 expression via phosphatidylinositol 3-kinase/Akt/nuclear factor-κB cascade in human breast cancer cells
    • DOI 10.1210/en.2004-1535
    • Saitoh M, , M. Ohmichi, K. Takahashi, J. Kawagoe, T. Ohta, M. Doshida, T. Takahashi, H. Igarashi, A. Mori-Abe, B. Du, S. Tsutsumi, H. Kurachi: Medroxyprogesterone acetate induces cell proliferation through up-regulation of cyclin D1 expression via phosphatidylinositol 3-kinase/Akt/nuclear factor-kappaB cascade in human breast cancer cells. Endocrinology 146, 4917-4925 (2005) (Pubitemid 41446630)
    • (2005) Endocrinology , vol.146 , Issue.11 , pp. 4917-4925
    • Saitoh, M.1    Ohmichi, M.2    Takahashi, K.3    Kawagoe, J.4    Ohta, T.5    Doshida, M.6    Takahashi, T.7    Igarashi, H.8    Mori-Abe, A.9    Du, B.10    Tsutsumi, S.11    Kurachi, H.12
  • 3
    • 0038583811 scopus 로고    scopus 로고
    • The effect of progesterone and synthetic progestins on serum- and estradiol-stimulated proliferation of human breast cancer cells
    • DOI 10.1055/s-2003-39061
    • Seeger H, D. Wallwiener, A. O. Mueck: The effect of progesterone and synthetic progestins on serum-and estradiol-stimulated proliferation of human breast cancer cells. Horm Metab Res 35, 76-80 (2003) (Pubitemid 36583677)
    • (2003) Hormone and Metabolic Research , vol.35 , Issue.2 , pp. 76-80
    • Seeger, H.1    Wallwiener, D.2    Mueck, A.O.3
  • 4
    • 34547757971 scopus 로고    scopus 로고
    • WISDOM group: Main morbidities recorded in the women's international study of long duration oestrogen after menopause (WISDOM): A randomised controlled trial of hormone replacement therapy in postmenopausal women
    • Vickers M. R, A. H. MacLennan, B. Lawton, D. Ford, J. Martin, S. K. Meredith, B. L. DeStavola, S. Rose, A. Dowell, H. C. Wilkes, J. H. Darbyshire, T. W. Meade, WISDOM group: Main morbidities recorded in the women's international study of long duration oestrogen after menopause (WISDOM): a randomised controlled trial of hormone replacement therapy in postmenopausal women. BMJ 335, 239-251 (2007)
    • (2007) BMJ , vol.335 , pp. 239-251
    • Vickers, M.R.1    MacLennan, A.H.2    Lawton, B.3    Ford, D.4    Martin, J.5    Meredith, S.K.6    Destavola, B.L.7    Rose, S.8    Dowell, A.9    Wilkes, H.C.10    Darbyshire, J.H.11    Meade, T.W.12
  • 5
    • 0742318858 scopus 로고    scopus 로고
    • Changes in the use of postmenopausal hormone therapy after the publication of clinical trial results
    • Haas J. S, C. P. Kaplan, E. P. Gerstenberger, K. Kerlikowske: Changes in the use of postmenopausal hormone therapy after the publication of clinical trial results. Ann Intern Med 140, 184-188 (2004)
    • (2004) Ann Intern Med , vol.140 , pp. 184-188
    • Haas, J.S.1    Kaplan, C.P.2    Gerstenberger, E.P.3    Kerlikowske, K.4
  • 6
    • 0346599193 scopus 로고    scopus 로고
    • National use of postmenopausal hormone therapy: Annual trends and response to recent evidence
    • DOI 10.1001/jama.291.1.47
    • Hersh A. L, M. L. Stefanick, R. S. Stafford: National use of postmenopausal hormone therapy: annual trends and response to recent evidence. JAMA 291, 47-53 (2004) (Pubitemid 38040534)
    • (2004) Journal of the American Medical Association , vol.291 , Issue.1 , pp. 47-53
    • Hersh, A.L.1    Stefanick, M.L.2    Stafford, R.S.3
  • 7
    • 33745876233 scopus 로고    scopus 로고
    • Neuropathology of older persons without cognitive impairment from two community-based studies
    • DOI 10.1212/01.wnl.0000219668.47116.e6, PII 0000611420060627000014
    • Bennett D. A, J. A. Schneider, Z. Arvanitakis, J. F. Kelly N. T. Aggarwal, R. C. Shah, R. S. Wilson: Neuropathology of older persons without cognitive impairment from two community-based studies. Neurology 66, 1837-1844 (2006) (Pubitemid 44049813)
    • (2006) Neurology , vol.66 , Issue.12 , pp. 1837-1844
    • Bennett, D.A.1    Schneider, J.A.2    Arvanitakis, Z.3    Kelly, J.F.4    Aggarwal, N.T.5    Shah, R.C.6    Wilson, R.S.7
  • 12
    • 0030748719 scopus 로고    scopus 로고
    • A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease: The Baltimore Longitudinal Study of Aging
    • Kawas C, S. Resnick, A. Morrison, R. Brookmeyer, M. Corrada, A. Zonderman, C. Bacal, D. D. Lingle, E. Metter: A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease: the Baltimore Longitudinal Study of Aging. Neurology 48, 1517-1521 (1997)
    • (1997) Neurology , vol.48 , pp. 1517-1521
    • Kawas, C.1    Resnick, S.2    Morrison, A.3    Brookmeyer, R.4    Corrada, M.5    Zonderman, A.6    Bacal, C.7    Lingle, D.D.8    Metter, E.9
  • 13
    • 0028085516 scopus 로고
    • Estrogen deficiency and risk of Alzheimer's disease in women
    • Paganini-Hill A, V. Henderson: Estrogen deficiency and risk of Alzheimer's disease in women. Am J Epidemiol 140, 256-261 (1994) (Pubitemid 24231911)
    • (1994) American Journal of Epidemiology , vol.140 , Issue.3 , pp. 256-261
    • Paganini-Hill, A.1    Henderson, V.W.2
  • 15
    • 0030591669 scopus 로고    scopus 로고
    • Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease
    • DOI 10.1016/S0140-6736(96)03356-9
    • Tang M. X, D. Jacobs, Y. Stern, K. Marder, P. Schofield, B. Gurland, H. Andrews, R. Mayeux: Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease. Lancet 348, 429-432 (1996) (Pubitemid 26267873)
    • (1996) Lancet , vol.348 , Issue.9025 , pp. 429-432
    • Tang, M.-X.1    Jacobs, D.2    Stern, Y.3    Marder, K.4    Schofieid, P.5    Garland, B.6    Andrews, H.7    Mayeux, R.8
  • 19
    • 34948829010 scopus 로고    scopus 로고
    • Increased risk of cognitive impairment or dementia in women who underwent oophorectomy before menopause
    • DOI 10.1212/01.wnl.0000276984.19542.e6
    • Rocca W. A, J. H. Bower, D. M. Maraganore, J. E. Ahlskog, B. R. Grossardt, M. de Andrade, and L. J. Melton III: Increased risk of cognitive impairment or dementia in women who underwent oophorectomy before menopause Neurology 69, 1074-1083 (2007) (Pubitemid 47517552)
    • (2007) Neurology , vol.69 , Issue.11 , pp. 1074-1083
    • Rocca, W.A.1    Bower, J.H.2    Maraganore, D.M.3    Ahlskog, J.E.4    Grossardt, B.R.5    De Andrade, M.6    Melton, L.J.7
  • 21
    • 0034643897 scopus 로고    scopus 로고
    • Effects of estrogen on cognition, mood, and cerebral blood flow in AD: A controlled study
    • Wang P. N, S. Q. Liao, R. S. Liu, C. Y. Liu, H. T. Chao, S. R. Lu, H. Y. Yu, S. J. Wang, H. C. Liu: Effects of estrogen on cognition, mood, and cerebral blood flow in AD: a controlled study. Neurology 54, 2061-2066 (2000) (Pubitemid 30397202)
    • (2000) Neurology , vol.54 , Issue.11 , pp. 2061-2066
    • Wang, P.N.1    Liao, S.Q.2    Liu, R.S.3    Liu, C.Y.4    Chao, H.T.5    Lu, S.R.6    Yu, H.Y.7    Wang, S.J.8    Liu, H.C.9
  • 24
    • 0035964288 scopus 로고    scopus 로고
    • High-dose estradiol improves cognition for women with ad results of a randomized study
    • Asthana S, L. D. Baker, S. Craft, F. Z. Stanczyk, R. C. Veith, M. A. Rasking, S. R. Plymate. High-dose estradiol improves cognition for women with AD: results of a randomized study. Neurology 57, 605-612 (2001) (Pubitemid 32782986)
    • (2001) Neurology , vol.57 , Issue.4 , pp. 605-612
    • Asthana, S.1    Baker, L.D.2    Craft, S.3    Stanczyk, F.Z.4    Veith, R.C.5    Raskind, M.A.6    Plymate, S.R.7
  • 27
    • 0028895128 scopus 로고
    • Estrogen replacement therapy and stroke
    • Paganini-Hill A: Estrogen replacement therapy and stroke. Prog Cardiovasc Dis 38, 223-242 (1995)
    • (1995) Prog Cardiovasc Dis , vol.38 , pp. 223-242
    • Paganini-Hill, A.1
  • 28
    • 0035386291 scopus 로고    scopus 로고
    • Brain damage, sex hormones and recovery: A new role for progesterone and estrogen?
    • DOI 10.1016/S0166-2236(00)01821-X, PII S016622360001821X
    • Stein D. G.: Brain damage, sex hormones and recovery: a new role for progesterone and estrogen? Trends Neurosci 24, 386-91 (2001) (Pubitemid 32938541)
    • (2001) Trends in Neurosciences , vol.24 , Issue.7 , pp. 386-391
    • Stein, D.G.1
  • 29
    • 0035659926 scopus 로고    scopus 로고
    • Stroke risk in older men and women: Aspirin, estrogen, exercise, vitamins, and other factors
    • Paganini-Hill A, M. Perez Barreto: Stroke risk in older men and women: aspirin, estrogen, exercise, vitamins, and other factors. J Gend Specif Med 4, 18-28 (2001) (Pubitemid 34023959)
    • (2001) Journal of Gender-Specific Medicine , vol.4 , Issue.2 , pp. 18-28
    • Paganini-Hill, A.1    Perez Barreto, M.2
  • 30
    • 14844337011 scopus 로고    scopus 로고
    • Estrogens, progestins, menopause and neurodegeneration: Basic and clinical studies
    • DOI 10.1007/s00018-004-4382-2
    • Simpkins J. W, S. H. Yang, Y. Wen, M. Singh: Estrogens, progestins, menopause and neurodegeneration: basic and clinical studies. Cell Mol Life Sci 62, 271-280 (2005) (Pubitemid 40379242)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.3 , pp. 271-280
    • Simpkins, J.W.1    Yang, S.-H.2    Wen, Y.3    Singh, M.4
  • 35
    • 0026775822 scopus 로고
    • A pilot study of the effect upon multiple sclerosis of the menopause, hormone replacement therapy and the menstrual cycle
    • Smith R, J. W. Studd: A pilot study of the effect upon multiple sclerosis of the menopause, hormone replacement therapy and the menstrual cycle. J R Soc Med 85, 612-613 (1992)
    • (1992) J R Soc Med , vol.85 , pp. 612-613
    • Smith, R.1    Studd, J.W.2
  • 36
    • 33748075167 scopus 로고    scopus 로고
    • Symptoms of multiple sclerosis in women in relation to sex steroid exposure
    • DOI 10.1016/j.maturitas.2005.10.003, PII S0378512205002628
    • Holmqvist P, , M. Wallberg, M. Hammar, A. M. Landtblom, J. Brynhildsen: Symptoms of multiple sclerosis in women in relation to sex steroid exposure. Maturitas 54, 149-153 (2006) (Pubitemid 44294287)
    • (2006) Maturitas , vol.54 , Issue.2 , pp. 149-153
    • Holmqvist, P.1    Wallberg, M.2    Hammar, M.3    Landtblom, A.-M.4    Brynhildsen, J.5
  • 37
    • 0038512171 scopus 로고    scopus 로고
    • Hormone-based therapies in MS
    • Voskuhl R. R: Hormone-based therapies in MS. Int MS J 10, 60-66 (2003) (Pubitemid 36717792)
    • (2003) International MS Journal , vol.10 , Issue.2 , pp. 60-66
    • Voskuhl, R.R.1
  • 39
    • 35648929212 scopus 로고    scopus 로고
    • Pregnancy and multiple sclerosis
    • DOI 10.1055/s-2007-991127
    • Houtchens M. K, : Pregnancy and multiple sclerosis. Semin Neurol 27, 434-441. (2007) (Pubitemid 350022487)
    • (2007) Seminars in Neurology , vol.27 , Issue.5 , pp. 434-441
    • Houtchens, M.K.1
  • 40
    • 0024299370 scopus 로고
    • Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
    • Mahley R. W: Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science 240, 622-630 (1988)
    • (1988) Science , vol.240 , pp. 622-630
    • Mahley, R.W.1
  • 42
    • 0021326066 scopus 로고
    • Human apolipoprotein A-I polymorphism. Identification of amino acid substitutions in three electrophoretic variants of the Munster-3 type
    • Menzel H. J, G. Assmann, S. C. Rall Jr., K. H. Weisgraber R. W. Mahley: Human apolipoprotein A-I polymorphism. Identification of amino acid substitutions in three electrophoretic variants of the Munster-3 type, J Biol Chem 259, 3070-3076 (1984) (Pubitemid 14162546)
    • (1984) Journal of Biological Chemistry , vol.259 , Issue.5 , pp. 3070-3076
    • Menzel, H.-J.1    Assmann, G.2    Rall Jr., S.C.3
  • 44
    • 0028303072 scopus 로고
    • Apolipoprotein E: Structure-function relationships
    • Weisgraber K. H: Apolipoprotein E: structure-function relationships. Adv Protein Chem 45, 249-302 (1994) (Pubitemid 24139890)
    • (1994) Advances in Protein Chemistry , vol.45 , pp. 249-302
    • Weisgraber, K.H.1
  • 45
    • 0023860891 scopus 로고
    • Apolipoprotein E polymorphism and atherosclerosis
    • Davignon J, R. E. Gregg, C. F. Sing: Apolipoprotein E polymorphism and atherosclerosis, Arteriosclerosis 8, 1-21 (1988) (Pubitemid 18049171)
    • (1988) Arteriosclerosis , vol.8 , Issue.1 , pp. 1-21
    • Davignon, J.1    Gregg, R.E.2    Sing, C.F.3
  • 46
    • 0034836428 scopus 로고    scopus 로고
    • LRP: A multifunctional scavenger and signaling receptor
    • DOI 10.1172/JCI200113992
    • Herz J, D. K. Strickland: LRP: a multifunctional scavenger and signaling receptor. J Clin Invest 108, 779-784 (2001) (Pubitemid 32880284)
    • (2001) Journal of Clinical Investigation , vol.108 , Issue.6 , pp. 779-784
    • Herz, J.1    Strickland, D.K.2
  • 47
    • 0035997373 scopus 로고    scopus 로고
    • Lipoprotein receptors in the nervous system
    • DOI 10.1146/annurev.biochem.71.110601.135342
    • Herz J, H. H. Bock: Lipoprotein receptors in the nervous system. Ann Rev Biochem 71, 405-434 (2002) (Pubitemid 34800226)
    • (2002) Annual Review of Biochemistry , vol.71 , pp. 405-434
    • Herz, J.1    Bock, H.H.2
  • 48
    • 0141832797 scopus 로고    scopus 로고
    • Diverse role of LDL receptor-related protein in the clearance of proteases and in signaling
    • Strickland D. K, S. Ranganathan: Diverse role of LDL receptor-related protein in the clearance of proteases and in signaling. J Thromb Haemost 1, 1663-1670 (2003)
    • (2003) J Thromb Haemost , vol.1 , pp. 1663-1670
    • Strickland, D.K.1    Ranganathan, S.2
  • 50
    • 0035184372 scopus 로고    scopus 로고
    • Brain region-specific up-regulation of mouse apolipoprotein E by pharmacological estrogen treatments
    • DOI 10.1046/j.1471-4159.2001.00627.x
    • Levin-Allerhand J, B. S. McEwen, C. E. Lominska, D. B. Lubahn, K. S. Korach, J. D. Smith: Brain region-specific up-regulation of mouse apolipoprotein E by pharmacological estrogen treatments. J Neurochem 79, 796-803 (2001) (Pubitemid 33086517)
    • (2001) Journal of Neurochemistry , vol.79 , Issue.4 , pp. 796-803
    • Levin-Allerhand, J.1    McEwen, B.S.2    Lominska, C.E.3    Lubahn, D.B.4    Korach, K.S.5    Smith, J.D.6
  • 51
    • 0141671956 scopus 로고    scopus 로고
    • Regionally specific modulation of brain apolipoprotein E in the mouse during the estrous cycle and by exogenous 17β estradiol
    • DOI 10.1016/S0014-4886(03)00215-2
    • Struble R. G, E. R. Rosario, M. L. Kircher, S. M. Ludwig, P. J. McAdamis, K. Watabe, M. E. McAsey, C. Cady, B. P. Nathan: Regionally specific modulation of brain apolipoprotein E in the mouse during the estrous cycle and by exogenous 17β estradiol. Exp Neurol 183, 638-44 (2003) (Pubitemid 37205106)
    • (2003) Experimental Neurology , vol.183 , Issue.2 , pp. 638-644
    • Struble, R.G.1    Rosario, E.R.2    Kircher, M.L.3    Ludwig, S.M.4    McAdamis, P.J.5    Watabe, K.6    McAsey, M.E.7    Cady, C.8    Nathan, B.P.9
  • 52
    • 29144507690 scopus 로고    scopus 로고
    • Time course of response to estradiol replacement in ovariectomized mice: Brain apolipoprotein E and synaptophysin transiently increase and glial fibrillary acidic protein is suppressed
    • DOI 10.1016/j.expneurol.2005.09.008, PII S0014488605003328
    • McAsey M. E, C. Cady, L. M. Jackson, M. Li, S. Randall, B. P. Nathan, R. G. Struble: Time course of response to estradiol replacement in ovariectomized mice: brain apolipoprotein E and synaptophysin transiently increase and glial fibrillary acidic protein is suppressed. Exp Neurol 197, 197-205 (2006) (Pubitemid 41817233)
    • (2006) Experimental Neurology , vol.197 , Issue.1 , pp. 197-205
    • McAsey, M.E.1    Cady, C.2    Jackson, L.M.3    Li, M.4    Randall, S.5    Nathan, B.P.6    Struble, R.G.7
  • 53
    • 34047095238 scopus 로고    scopus 로고
    • Estradiol replacement increases the low-density lipoprotein receptor related protein (LRP) in the mouse brain
    • DOI 10.1016/j.neulet.2007.02.030, PII S030439400700184X
    • Cheng X, M. E. McAsey, M. Li, S. Randall, C. Cady, B. P. Nathan, R. G. Struble: Estradiol replacement increases the low-density lipoprotein receptor related protein (LRP) in the mouse brain. Neurosci Lett 417, 50-54 (2007) (Pubitemid 46517838)
    • (2007) Neuroscience Letters , vol.417 , Issue.1 , pp. 50-54
    • Cheng, X.1    McAsey, M.E.2    Li, M.3    Randall, S.4    Cady, C.5    Nathan, B.P.6    Struble, R.G.7
  • 55
    • 10044242726 scopus 로고    scopus 로고
    • Genetic association of low density lipoprotein receptor and Alzheimer's disease
    • DOI 10.1016/j.neurobiolaging.2004.09.001, PII S0197458004002738
    • Gopalraj R. K, H. Zhu, J. F. Kelly, M. Mendiondo, J. F. Pulliam, D. A. Bennett, S. Estus: Genetic association of low density lipoprotein receptor and Alzheimer's disease. Neurobiol Aging 26, 1-7 (2005) (Pubitemid 39600585)
    • (2005) Neurobiology of Aging , vol.26 , Issue.1 , pp. 1-7
    • Gopalraj, R.K.1    Zhu, H.2    Kelly, J.F.3    Mendiondo, M.4    Pulliam, J.F.5    Bennett, D.A.6    Estus, S.7
  • 57
    • 4143138471 scopus 로고    scopus 로고
    • In vivo effects of ApoE and clusterin on amyloid-beta metabolism and neuropathology
    • Holtzman D. M: In vivo effects of ApoE and clusterin on amyloid-beta metabolism and neuropathology. J Mol Neurosci 23, 247-254 (2004)
    • (2004) J Mol Neurosci , vol.23 , pp. 247-254
    • Holtzman, D.M.1
  • 58
    • 34250811784 scopus 로고    scopus 로고
    • LRP in amyloid-beta production and metabolism
    • Bu G, J. Cam, C. Zerbinatti: LRP in amyloid-beta production and metabolism. Ann N Y Acad Sci. 1086, 35-53 (2006)
    • (2006) Ann N y Acad Sci. , vol.1086 , pp. 35-53
    • Bu, G.1    Cam, J.2    Zerbinatti, C.3
  • 61
    • 34748903283 scopus 로고    scopus 로고
    • Association of APOE with Parkinson disease age-at-onset in women
    • DOI 10.1016/j.neulet.2006.07.080, PII S0304394006006707
    • Buchanan D. D, P. A. Silburn, J. A. Prince, G. D. Mellick: Association of APOE with Parkinson disease ageat-onset in women. Neurosci Lett 411, 185-188 (2007) (Pubitemid 44828271)
    • (2007) Neuroscience Letters , vol.411 , Issue.3 , pp. 185-188
    • Buchanan, D.D.1    Silburn, P.A.2    Prince, J.A.3    Mellick, G.D.4
  • 63
    • 32944462422 scopus 로고    scopus 로고
    • Apolipoprotein E and dementia in Parkinson disease: A meta-analysis
    • DOI 10.1001/archneur.63.2.189
    • Huang X, P. Chen, D. I. Kaufer, A. I. Troster, C. Poole: Apolipoprotein E and dementia in Parkinson disease: a meta-analysis. Arch Neurol 63, 189-193 (2006) (Pubitemid 43261729)
    • (2006) Archives of Neurology , vol.63 , Issue.2 , pp. 189-193
    • Huang, X.1    Chen, P.2    Kaufer, D.I.3    Troster, A.I.4    Poole, C.5
  • 64
    • 0036219387 scopus 로고    scopus 로고
    • Differences in tau and apolipoprotein E polymorphism frequencies in sporadic frontotemporal lobar degeneration syndromes
    • Short R. A, N. R. Graff-Radford, J. Adamson, M. Baker, M. Hutton: Differences in tau and apolipoprotein E polymorphism frequencies in sporadic frontotemporal lobar degeneration syndromes. Arch Neurol 59, 611-615 (2002) (Pubitemid 34289965)
    • (2002) Archives of Neurology , vol.59 , Issue.4 , pp. 611-615
    • Short, R.A.1    Graff-Radford, N.R.2    Adamson, J.3    Baker, M.4    Hutton, M.5
  • 70
    • 0035885774 scopus 로고    scopus 로고
    • Association of APOE ε4 allele with survival in amyotrophic lateral sclerosis
    • PII S0022510X0100569X
    • Drory V. E, M. Birnbaum, A. D. Korczyn, J. Chapman: Association of APOE epsilon4 allele with survival in amyotrophic lateral sclerosis. J Neurol Sci 190, 17-20 (2001) (Pubitemid 33713016)
    • (2001) Journal of the Neurological Sciences , vol.190 , Issue.1-2 , pp. 17-20
    • Drory, V.E.1    Birnbaum, M.2    Korczyn, A.D.3    Chapman, J.4
  • 74
    • 0034705091 scopus 로고    scopus 로고
    • Estrogen use, APOE, and cognitive decline: Evidence of gene-environment interaction
    • Yaffe K, M. Haan, A. Byers, C. Tangen, L. Kuller: Estrogen use, APOE, and cognitive decline: evidence of gene-environment interaction. Neurology 54, 1949-1954 (2000)
    • (2000) Neurology , vol.54 , pp. 1949-1954
    • Yaffe, K.1    Haan, M.2    Byers, A.3    Tangen, C.4    Kuller, L.5
  • 76
    • 33645802650 scopus 로고    scopus 로고
    • Familial Alzheimer disease in Latinos: Interaction between APOE, stroke, and estrogen replacement
    • DOI 10.1212/01.wnl.0000191300.38571.3e, PII 0000611420060110000012
    • Rippon G. A, M. X. Tang, J. H. Lee, R. Lantigua, M. Medrano, R. Mayeux: Familial Alzheimer disease in Latinos: interaction between APOE, stroke, and estrogen replacement. Neurology 66, 35-40 (2006) (Pubitemid 43739588)
    • (2006) Neurology , vol.66 , Issue.1 , pp. 35-40
    • Rippon, G.A.1    Tang, M.-X.2    Lee, J.H.3    Lantigua, R.4    Medrano, M.5    Mayeux, R.6
  • 78
    • 33947186953 scopus 로고    scopus 로고
    • Dose dependence and therapeutic window for the neuroprotective effects of 17β-estradiol when administered after cerebral ischemia
    • DOI 10.1016/j.neulet.2007.01.074, PII S0304394007000730
    • Liu R, X. Wang, Q. Liu, S. H. Yang, J. W. Simpkins: Dose dependence and therapeutic window for the neuroprotective effects of 17beta-estradiol when administered after cerebral ischemia. Neurosci Lett 415, 237-241 (2007) (Pubitemid 46400270)
    • (2007) Neuroscience Letters , vol.415 , Issue.3 , pp. 237-241
    • Liu, R.1    Wang, X.2    Liu, Q.3    Yang, S.-H.4    Simpkins, J.W.5
  • 80
    • 0032536475 scopus 로고    scopus 로고
    • Effects of gender and estradiol treatment on focal brain ischemia
    • DOI 10.1016/S0006-8993(97)00502-7, PII S0006899397005027
    • Zhang Y. Q, J. Shi, G. Rajakumar, A. L. Day, J. W. Simpkins: Effects of gender and estradiol treatment on focal brain ischemia. Brain Res 784, 321-324 (1998) (Pubitemid 28137875)
    • (1998) Brain Research , vol.784 , Issue.1-2 , pp. 321-324
    • Zhang, Y.-Q.1    Shi, J.2    Rajakumar, G.3    Day, A.L.4    Simpkins, J.W.5
  • 81
    • 0026099937 scopus 로고
    • Sex differences in postischemic neuronal necrosis in gerbils
    • Hall E. D, K. E. Pazara, K. L. Linseman: Sex differences in postischemic neuronal necrosis in gerbils. J Cereb Blood Flow Metab 11, 292-298 (1991)
    • (1991) J Cereb Blood Flow Metab , vol.11 , pp. 292-298
    • Hall, E.D.1    Pazara, K.E.2    Linseman, K.L.3
  • 82
    • 0030609088 scopus 로고    scopus 로고
    • Effects of 17β-estradiol on glucose transporter 1 expression and endothelial cell survival following focal ischemia in the rats
    • DOI 10.1007/s002210050216
    • Shi J, Y. Q. Zhang, J. W. Simpkins: Effects of 17betaestradiol on glucose transporter 1 expression and endothelial cell survival following focal ischemia in the rats. Exp Brain Res 117, 200-206 (1997) (Pubitemid 27488781)
    • (1997) Experimental Brain Research , vol.117 , Issue.2 , pp. 200-206
    • Shi, J.1    Zhang, Y.Q.2    Simpkins, J.W.3
  • 84
    • 0031904678 scopus 로고    scopus 로고
    • Estrogen-mediated neuroprotection after experimental stroke in male rats
    • Toung T. J, R. J. Traystman, P. D. Hurn: Estrogenmediated neuroprotection after experimental stroke in male rats. Stroke 29, 1666-1670 (1998) (Pubitemid 28365591)
    • (1998) Stroke , vol.29 , Issue.8 , pp. 1666-1670
    • Toung, T.J.K.1    Traystman, R.J.2    Hurn, P.D.3
  • 86
    • 0033976986 scopus 로고    scopus 로고
    • Neuroprotective effects of female gonadal steroids in reproductively senescent female rats
    • Alkayed N. J, S. J. Murphy, R. J. Traystman, P. D. Hurn, V. M. Miller: Neuroprotective effects of female gonadal steroids in reproductively senescent female rats. Stroke 31, 161-168 (2000) (Pubitemid 30035770)
    • (2000) Stroke , vol.31 , Issue.1 , pp. 161-168
    • Alkayed, N.J.1    Murphy, S.J.2    Traystman, R.J.3    Hurn, P.D.4
  • 87
    • 0033967462 scopus 로고    scopus 로고
    • Ovariectomy exacerbates and estrogen replacement attenuates photothrombotic focal ischemic brain injury in rats
    • Fukuda K, H. Yao, S. Ibayashi, T. Nakahara, H. Uchimura, M. Fujishima, E. D. Hall: Ovariectomy exacerbates and estrogen replacement attenuates photothrombotic focal ischemic brain injury in rats. Stroke 31, 155-160 (2000) (Pubitemid 30035769)
    • (2000) Stroke , vol.31 , Issue.1 , pp. 155-160
    • Fukuda, K.1    Yao, H.2    Ibayashi, S.3    Nakahara, T.4    Uchimura, H.5    Fujishima, M.6
  • 88
    • 0033816050 scopus 로고    scopus 로고
    • Neuroprotective effects of estrogens on hippocampal cells in adult female rats after status epilepticus
    • Veliskova J, L. Velisek, A. S. Galanopoulou, E. F. Sperber: Neuroprotective effects of estrogens on hippocampal cells in adult female rats after status epilepticus. Epilepsia 41, Suppl 6:S30-35 (2000)
    • (2000) Epilepsia , vol.41 , Issue.SUPPL. 6
    • Veliskova, J.1    Velisek, L.2    Galanopoulou, A.S.3    Sperber, E.F.4
  • 89
    • 0035118001 scopus 로고    scopus 로고
    • Neuroprotective effects of estradiol in middle-aged female rats
    • DOI 10.1210/en.142.1.43
    • Dubal D. B, P. M. Wise: Neuroprotective effects of estradiol in middle-aged female rats. Endocrinology 142, 43-48 (2001) (Pubitemid 32183664)
    • (2001) Endocrinology , vol.142 , Issue.1 , pp. 43-48
    • Dubal, D.B.1    Wise, P.M.2
  • 90
    • 0035805173 scopus 로고    scopus 로고
    • Deleterious effect of β-estradiol in a rat model of transient forebrain ischemia
    • DOI 10.1016/S0006-8993(01)02278-8, PII S0006899301022788
    • Harukuni I, P. D. Hurn, B. J. Crain: Deleterious effect of beta-estradiol in a rat model of transient forebrain ischemia. Brain Res 900, 137-142 (2001) (Pubitemid 32452273)
    • (2001) Brain Research , vol.900 , Issue.1 , pp. 137-142
    • Harukuni, I.1    Hurn, P.D.2    Crain, B.J.3
  • 92
    • 0037159631 scopus 로고    scopus 로고
    • Loss of benefit from estrogen replacement therapy in diabetic ovariectomized female rats subjected to transient forebrain ischemia
    • DOI 10.1016/S0006-8993(02)03484-4, PII S0006899302034844
    • Santizo R. A, H. L. Xu, S. Ye, V. L. Baughman, D. A. Pelligrino: Loss of benefit from estrogen replacement therapy in diabetic ovariectomized female rats subjected to transient forebrain ischemia. Brain Res 956, 86-95 (2002) (Pubitemid 35335560)
    • (2002) Brain Research , vol.956 , Issue.1 , pp. 86-95
    • Santizo, R.A.1    Xu, H.-L.2    Ye, S.3    Baughman, V.L.4    Pelligrino, D.A.5
  • 93
    • 0037081302 scopus 로고    scopus 로고
    • Proestrus levels of estradiol during transient global cerebral ischemia improves the histological outcome of the hippocampal CA1 region: Perfusion-dependent and-independent mechanisms
    • DOI 10.1016/S0022-510X(01)00648-7, PII S0022510X01006487
    • He Z, Y. J. He, A. L. Day, J. W. Simpkins: Proestrus levels of estradiol during transient global cerebral ischemia improves the histological outcome of the hippocampal CA1 region: perfusion-dependent and-independent mechanisms. J Neurol Sci 193, 79-87 (2002) (Pubitemid 34098938)
    • (2002) Journal of the Neurological Sciences , vol.193 , Issue.2 , pp. 79-87
    • He, Z.1    He, Y.-J.2    Day, A.L.3    Simpkins, J.W.4
  • 94
    • 0037217490 scopus 로고    scopus 로고
    • Tamoxifen, a selective estrogen receptor modulator, reduces ischemic damage caused by middle cerebral artery occlusion in the ovariectomized female rat
    • DOI 10.1159/000068332
    • Mehta S. H, K. M. Dhandapani, L. M. De Sevilla, R. C. Webb, V. B. Mahesh, D. W. Brann: Tamoxifen, a selective estrogen receptor modulator, reduces ischemic damage caused by middle cerebral artery occlusion in the ovariectomized female rat. Neuroendocrinology 77, 44-50 (2003) (Pubitemid 36302421)
    • (2003) Neuroendocrinology , vol.77 , Issue.1 , pp. 44-50
    • Mehta, S.H.1    Dhandapani, K.M.2    De Sevilla, L.M.3    Webb, R.C.4    Mahesh, V.B.5    Brann, D.W.6
  • 95
    • 0345714772 scopus 로고    scopus 로고
    • 17β-Estradiol extends ischemic thresholds and exerts neuroprotective effects in cerebral subcortex against transient focal cerebral ischemia in rats
    • DOI 10.1016/j.brainres.2003.07.006
    • Fan T, S.H. Yang, E. Johnson, B. Osteen, R. Hayes, A. L. Day, J. W. Simpkins: 17beta-Estradiol extends ischemic thresholds and exerts neuroprotective effects in cerebral subcortex against transient focal cerebral ischemia in rats. Brain Res 993, 10-17 (2003) (Pubitemid 37464578)
    • (2003) Brain Research , vol.993 , Issue.1-2 , pp. 10-17
    • Fan, T.1    Yang, S.-H.2    Johnson, E.3    Osteen, B.4    Hayes, R.5    Day, A.L.6    Simpkins, J.W.7
  • 96
    • 0037450414 scopus 로고    scopus 로고
    • Estrogen prevents the loss of CA1 hippocampal neurons in gerbils after ischemic injury
    • DOI 10.1016/S0306-4522(02)00790-X
    • Shughrue P. J, I. Merchenthaler: Estrogen prevents the loss of CA1 hippocampal neurons in gerbils after ischemic injury. Neuroscience 116, 851-861 (2003) (Pubitemid 36160578)
    • (2003) Neuroscience , vol.116 , Issue.3 , pp. 851-861
    • Shughrue, P.J.1    Merchenthaler, I.2
  • 97
    • 2442534125 scopus 로고    scopus 로고
    • Estrogen attenuates nuclear factor-kappa B activation induced by transient cerebral ischemia
    • DOI 10.1016/j.brainres.2004.02.019, PII S0006899304002628
    • Wen Y, S. Yang, R. Liu, E. Perez, K. D. Yi, P. Koulen, J. W. Simpkins: Estrogen attenuates nuclear factor-kappa B activation induced by transient cerebral ischemia. Brain Res 1008, 147-154 (2004) (Pubitemid 38624044)
    • (2004) Brain Research , vol.1008 , Issue.2 , pp. 147-154
    • Wen, Y.1    Yang, S.2    Liu, R.3    Perez, E.4    Yi, K.D.5    Koulen, P.6    Simpkins, J.W.7
  • 98
    • 3242792686 scopus 로고    scopus 로고
    • Estrogen replacement treatment in diabetic ovariectomized female rats potentiates postischemic leukocyte adhesion in cerebral venules
    • DOI 10.1161/01.STR.0000135016.24349.9F
    • Xu H. L, V. L. Baughman, D. A. Pelligrino: Estrogen replacement treatment in diabetic ovariectomized female rats potentiates postischemic leukocyte adhesion in cerebral venules. Stroke 35, 1974-1978 (2004) (Pubitemid 38971886)
    • (2004) Stroke , vol.35 , Issue.8 , pp. 1974-1978
    • Xu, H.-L.1    Baughman, V.L.2    Pelligrino, D.A.3
  • 101
    • 33644560650 scopus 로고    scopus 로고
    • Estrogen therapy: Does it help or hurt the adult and aging brain? Insights derived from animal models
    • Wise P. M.: Estrogen therapy: does it help or hurt the adult and aging brain? Insights derived from animal models. Neuroscience 138, 831-835 (2006)
    • (2006) Neuroscience , vol.138 , pp. 831-835
    • Wise, P.M.1
  • 102
    • 33847677305 scopus 로고    scopus 로고
    • Acute pretreatment with estradiol protects against CA1 cell loss and spatial learning impairments resulting from transient global ischemia
    • DOI 10.1016/j.yhbeh.2006.12.002, PII S0018506X06003357
    • Sandstrom N. J, M. H. Rowan: Acute pretreatment with estradiol protects against CA1 cell loss and spatial learning impairments resulting from transient global ischemia. Horm Behav. 51, 335-345 (2007) (Pubitemid 46365685)
    • (2007) Hormones and Behavior , vol.51 , Issue.3 , pp. 335-345
    • Sandstrom, N.J.1    Rowan, M.H.2
  • 103
    • 0033806888 scopus 로고    scopus 로고
    • Estradiol protects against ischemic brain injury in middle-aged rats
    • Wise P. M, D.B. Dubal: Estradiol protects against ischemic brain injury in middle-aged rats. Biol Reprod 63, 982-985 (2000)
    • (2000) Biol Reprod , vol.63 , pp. 982-985
    • Wise, P.M.1    Dubal, D.B.2
  • 104
    • 0033004253 scopus 로고    scopus 로고
    • Estrogen provides neuroprotection in transient forebrain ischemia through perfusion-independent mechanisms in rats
    • Wang Q, R. Santizo, V. L. Baughman, D. A. Pelligrino, C. Iadecola: Estrogen provides neuroprotection in transient forebrain ischemia through perfusionindependent mechanisms in rats. Stroke 30, 630-637 (1999) (Pubitemid 29115403)
    • (1999) Stroke , vol.30 , Issue.3 , pp. 630-637
    • Wang, Q.1    Santizo, R.2    Baughman, V.L.3    Pelligrino, D.A.4
  • 105
    • 0036708602 scopus 로고    scopus 로고
    • Effects of 17β-estradiol on blood-brain barrier disruption during focal ischemia in rats
    • DOI 10.1055/s-2002-34794
    • Chi O. Z, X. Liu, H. R. Weiss: Effects of 17betaestradiol on blood-brain barrier disruption during focal ischemia in rats. Horm Metab Res 34, 530-534. (2002) (Pubitemid 35192241)
    • (2002) Hormone and Metabolic Research , vol.34 , Issue.9 , pp. 530-534
    • Chi, O.Z.1    Liu, X.2    Weiss, H.R.3
  • 106
    • 14644435096 scopus 로고    scopus 로고
    • Detrimental effects of 17β-oestradiol after permanent middle cerebral artery occlusion
    • DOI 10.1038/sj.jcbfm.9600031
    • Bingham D, I. M. Macrae, H. V. Carswell. Detrimental effects of 17beta-oestradiol after permanent middle cerebral artery occlusion. J Cereb Blood Flow Metab 25, 414-420 (2005) (Pubitemid 40315883)
    • (2005) Journal of Cerebral Blood Flow and Metabolism , vol.25 , Issue.3 , pp. 414-420
    • Bingham, D.1    Macrae, I.M.2    Carswell, H.V.3
  • 107
    • 13844267505 scopus 로고    scopus 로고
    • Effects of 17β-oestradiol on cerebral ischaemic damage and lipid peroxidation
    • DOI 10.1016/j.brainres.2004.12.052
    • Gordon K. B, I. M. Macrae, V. Carswell: Effects of 17beta-oestradiol on cerebral ischaemic damage and lipid peroxidation. Brain Res 1036, 155-162 (2005) (Pubitemid 40255855)
    • (2005) Brain Research , vol.1036 , Issue.1-2 , pp. 155-162
    • Gordon, K.B.1    Macrae, I.M.2    Carswell, H.V.O.3
  • 108
    • 27744529107 scopus 로고    scopus 로고
    • Estradiol increases brain lesions in the cortex and lateral striatum after transient occlusion of the middle cerebral artery in rats: No effect of ischemia on galanin in the stroke area but decreased levels in the hippocampus
    • DOI 10.1016/j.peptides.2005.04.013, PII S0196978105001853
    • Theodorsson A, E .Theodorsson: Estradiol increases brain lesions in the cortex and lateral striatum after transient occlusion of the middle cerebral artery in rats: no effect of ischemia on galanin in the stroke area but decreased levels in the hippocampus. Peptides 26, 2257-2264 (2005) (Pubitemid 41584093)
    • (2005) Peptides , vol.26 , Issue.11 , pp. 2257-2264
    • Theodorsson, A.1    Theodorsson, E.2
  • 109
    • 24044548988 scopus 로고    scopus 로고
    • 17β-estradiol potentiates ischemia-reperfusion injury in diabetic ovariectomized female rats
    • DOI 10.1016/j.brainres.2005.05.069, PII S0006899305008152
    • Yong Y, H. J. Xie, Y. F. Zhang, Q. D. Yang, D. F. Liao, H. L. Yang, P. K. Yan, Z. J. Liu: 17beta-estradiol potentiates ischemia-reperfusion injury in diabetic ovariectomized female rats. Brain Res 1054, 192-199 (2005) (Pubitemid 41219349)
    • (2005) Brain Research , vol.1054 , Issue.2 , pp. 192-199
    • Yong, Y.1    Xie, H.-J.2    Zhang, Y.-F.3    Yang, Q.-D.4    Liao, D.-F.5    Yang, H.-L.6    Yan, P.-K.7    Liu, Z.-J.8
  • 110
    • 31444449417 scopus 로고    scopus 로고
    • Acute and chronic estradiol treatments reduce memory deficits induced by transient global ischemia in female rats
    • DOI 10.1016/j.yhbeh.2005.07.010, PII S0018506X05001765
    • Gulinello M, D. Lebesgue, T. Jover-Mengual, R. S. Zukin, A. M. Etgen: Acute and chronic estradiol treatments reduce memory deficits induced by transient global ischemia in female rats. Horm Behav 49, 246-260 (2006) (Pubitemid 43152499)
    • (2006) Hormones and Behavior , vol.49 , Issue.2 , pp. 246-260
    • Gulinello, M.1    Lebesgue, D.2    Jover-Mengual, T.3    Zukin, R.S.4    Etgen, A.M.5
  • 112
    • 33645993568 scopus 로고    scopus 로고
    • Estradiol prevents the focal cerebral ischemic injury-induced decrease of forkhead transcription factors phosphorylation
    • Won C. K, H. H. Ji, P. O. Koh: Estradiol prevents the focal cerebral ischemic injury-induced decrease of forkhead transcription factors phosphorylation. Neurosci Lett 398, 39-43 (2006)
    • (2006) Neurosci Lett , vol.398 , pp. 39-43
    • Won, C.K.1    Ji, H.H.2    Koh, P.O.3
  • 113
    • 33745887475 scopus 로고    scopus 로고
    • Effects of 17β-estradiol on blood-brain barrier disruption during focal cerebral ischemia in younger and older rats
    • DOI 10.1055/s-2006-944521
    • Chi O. Z, C. Hunter, X. Liu, H.R. Weiss: Effects of 17beta-estradiol on blood-brain barrier disruption during focal cerebral ischemia in younger and older rats. Horm Metab Res 38, 377-381 (2006) (Pubitemid 44047959)
    • (2006) Hormone and Metabolic Research , vol.38 , Issue.6 , pp. 377-381
    • Chi, O.Z.1    Hunter, C.2    Liu, X.3    Weiss, H.R.4
  • 114
    • 0036792014 scopus 로고    scopus 로고
    • Estrogen is neuroprotective via an apolipoprotein E-dependent mechanism in a mouse model of global ischemia
    • Horsburgh K, I. M. Macrae, H. Carswell: Estrogen is neuroprotective via an apolipoprotein E-dependent mechanism in a mouse model of global ischemia. J Cereb Blood Flow Metab 22, 1189-1195 (2002)
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 1189-1195
    • Horsburgh, K.1    MacRae, I.M.2    Carswell, H.3
  • 115
    • 0242570611 scopus 로고    scopus 로고
    • ApoE isoforms affect neuronal N-methyl-D-aspartate calcium responses and toxicity via receptor-mediated processes
    • DOI 10.1016/j.neuroscience.2003.08.017
    • Qiu Z, K. A. Crutcher, B. T. Hyman, G. W. Rebeck: ApoE isoforms affect neuronal N-methyl-D-aspartate calcium responses and toxicity via receptor-mediated processes. Neuroscience 122, 291-303 (2003) (Pubitemid 37410161)
    • (2003) Neuroscience , vol.122 , Issue.2 , pp. 291-303
    • Qiu, Z.1    Crutcher, K.A.2    Hyman, B.T.3    Rebeck, G.W.4
  • 116
    • 1642336131 scopus 로고    scopus 로고
    • Neuroserpin: A selective inhibitor of tissue-type plasminogen activator in the central nervous system
    • Yepes M, D. A. Lawrence: Neuroserpin: a selective inhibitor of tissue-type plasminogen activator in the central nervous system. Thromb Haemost 91, 457-464 (2004) (Pubitemid 38396867)
    • (2004) Thrombosis and Haemostasis , vol.91 , Issue.3 , pp. 457-464
    • Yepes, M.1    Lawrence, D.A.2
  • 119
    • 0025411855 scopus 로고
    • Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood
    • Gould E, C. S. Woolley, M. Frankfurt, B. S. McEwen: Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood. J Neurosci 10, 1286-1291 (1990)
    • (1990) J Neurosci , vol.10 , pp. 1286-1291
    • Gould, E.1    Woolley, C.S.2    Frankfurt, M.3    McEwen, B.S.4
  • 120
    • 0026627947 scopus 로고
    • Estradiol mediates fluctuation in hippocampal synapse density during the estrous cycle in the adult rat
    • Woolley C. S, B. S. McEwen: Estradiol mediates fluctuation in hippocampal synapse density during the estrous cycle in the adult rat. J Neurosci 12, 2549-2554 (1992)
    • (1992) J Neurosci , vol.12 , pp. 2549-2554
    • Woolley, C.S.1    McEwen, B.S.2
  • 121
    • 0033792318 scopus 로고    scopus 로고
    • Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles
    • Thiele C, M. J. Hannah, F. Fahrenholz, W. B. Huttner: Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles. Nat Cell Biol 2, 42-49. (2000)
    • (2000) Nat Cell Biol , vol.2 , pp. 42-49
    • Thiele, C.1    Hannah, M.J.2    Fahrenholz, F.3    Huttner, W.B.4
  • 122
    • 0035095494 scopus 로고    scopus 로고
    • Novel target sites for estrogen action in the dorsal hippocampus: An examination of synaptic proteins
    • DOI 10.1210/en.142.3.1284
    • Brake W. G. S. E. Alves, J. C. Dunlop, S. J. Lee, K. Bulloch, P. B. Allen, P. Greengard, B. S. McEwen: Novel target sites for estrogen action in the dorsal hippocampus: an examination of synaptic proteins. Endocrinology 142, 1284-1289 (2001) (Pubitemid 32202840)
    • (2001) Endocrinology , vol.142 , Issue.3 , pp. 1284-1289
    • Brake, W.G.1    Alves, S.E.2    Dunlop, J.C.3    Lee, S.J.4    Bulloch, K.5    Allen, P.B.6    Greengard, P.7    McEwen, B.S.8
  • 123
    • 0032080001 scopus 로고    scopus 로고
    • Increased synaptic sprouting in response to estrogen via an apolipoprotein E-dependent mechanism: Implications for Alzheimer's disease
    • Stone D. J, I. Rozovsky, T. E. Morgan, C. P. Anderson, C. E. Finch: Increased synaptic sprouting in response to estrogen via an apolipoprotein E-dependent mechanism: implications for Alzheimer's disease. J Neurosci 18, 3180-3185 (1998) (Pubitemid 28186010)
    • (1998) Journal of Neuroscience , vol.18 , Issue.9 , pp. 3180-3185
    • Stone, D.J.1    Rozovsky, I.2    Morgan, T.E.3    Anderson, C.P.4    Finch, C.E.5
  • 124
    • 0028030144 scopus 로고
    • Effects of estrogen replacement on the relative levels of choline acetyltransferase, trkA, and nerve growth factor messenger RNSAs in the basal forebrain and hippocampal formation of adult rats
    • DOI 10.1006/exnr.1994.1148
    • Gibbs R. B, D. Wu, L. B. Hersh, D. W. Pfaff: Effects of estrogen replacement on the relative levels of choline acetyltransferase, trkA, and nerve growth factor messenger RNAs in the basal forebrain and hippocampal formation of adult rats. Exp Neurol 129, 70-80 (1994) (Pubitemid 24344158)
    • (1994) Experimental Neurology , vol.129 , Issue.1 , pp. 70-80
    • Gibbs, R.B.1    Wu, D.2    Hersh, L.B.3    Pfaff, D.W.4
  • 125
    • 0029875358 scopus 로고    scopus 로고
    • Fluctuations in relative levels of choline acetyltransferase mRNA in different regions of the rat basal forebrain across the estrous cycle: Effects of estrogen and progesterone
    • Gibbs R. B: Fluctuations in relative levels of choline acetyltransferase mRNA in different regions of the rat basal forebrain across the estrous cycle: effects of estrogen and progesterone. J Neurosci 16, 1049-1055 (1996) (Pubitemid 26140861)
    • (1996) Journal of Neuroscience , vol.16 , Issue.3 , pp. 1049-1055
    • Gibbs, R.B.1
  • 126
    • 0021861330 scopus 로고
    • Estradiol increases choline acetyltransferase activity in specific basal forebrain nuclei and projection areas of female rats
    • DOI 10.1016/0014-4886(85)90108-6
    • Luine V. N: Estradiol increases choline acetyltransferase activity in specific basal forebrain nuclei and projection areas of female rats. Exp Neurol 89, 484-490 (1985) (Pubitemid 15040918)
    • (1985) Experimental Neurology , vol.89 , Issue.2 , pp. 484-490
    • Luine, V.N.1
  • 127
    • 0023935799 scopus 로고
    • Effects of estradiol and dexamethasone on choline acetyltransferase activity in various rat brain regions
    • Kaufman H, C. Vadasz, A. Lajtha: Effects of estradiol and dexamethasone on choline acetyltransferase activity in various rat brain regions. Brain Res 453, 389-392 (1988)
    • (1988) Brain Res , vol.453 , pp. 389-392
    • Kaufman, H.1    Vadasz, C.2    Lajtha, A.3
  • 128
    • 0025142166 scopus 로고
    • Chronic estradiol treatment alters central cholinergic function in the female rat: Effect on choline acetyltransferase activity, acetylcholine content, and nicotinic autoreceptor function
    • DOI 10.1016/0006-8993(90)90871-8
    • Lapchak P. A, D. M. Araujo, R. Quirion, A. Beaudet: Chronic estradiol treatment alters central cholinergic function in the female rat: effect on choline acetyltransferase activity, acetylcholine content, and nicotinic autoreceptor function. Brain Res 525, 249-255 (1990) (Pubitemid 20257743)
    • (1990) Brain Research , vol.525 , Issue.2 , pp. 249-255
    • Lapchak, P.A.1    Araujo, D.M.2    Quirion, R.3    Beaudet, A.4
  • 129
    • 0028224213 scopus 로고
    • Ovarian steroid deprivation results in a reversible learning impairment and compromised cholinergic function in female Sprague-Dawley rats
    • DOI 10.1016/0006-8993(94)91694-2
    • Singh M, E. M. Meyer, W. J. Millard, J. W. Simpkins: Ovarian steroid deprivation results in a reversible learning impairment and compromised cholinergic function in female Sprague-Dawley rats. Brain Res 644, 305-312 (1994) (Pubitemid 24127987)
    • (1994) Brain Research , vol.644 , Issue.2 , pp. 305-312
    • Singh, M.1    Meyer, E.M.2    Millard, W.J.3    Simpkins, J.W.4
  • 130
    • 0028918161 scopus 로고
    • The effect of ovariectomy and estradiol replacement on brainderived neurotrophic factor messenger ribonucleic acid expression in cortical and hippocampal brain regions of female Sprague-Dawley rats
    • Singh M, E. M. Meyer, J. W. Simpkins: The effect of ovariectomy and estradiol replacement on brainderived neurotrophic factor messenger ribonucleic acid expression in cortical and hippocampal brain regions of female Sprague-Dawley rats. Endocrinology 136, 2320-2324 (1995)
    • (1995) Endocrinology , vol.136 , pp. 2320-2324
    • Singh, M.1    Meyer, E.M.2    Simpkins, J.W.3
  • 131
    • 0030985859 scopus 로고    scopus 로고
    • Effects of estrogen on basal forebrain cholinergic neurons vary as a function of dose and duration of treatment
    • DOI 10.1016/S0006-8993(96)01432-1, PII S0006899396014321
    • Gibbs R. B: Effects of estrogen on basal forebrain cholinergic neurons vary as a function of dose and duration of treatment. Brain Res 757, 10-16 (1997) (Pubitemid 27244615)
    • (1997) Brain Research , vol.757 , Issue.1 , pp. 10-16
    • Gibbs, R.B.1
  • 132
    • 0345725010 scopus 로고    scopus 로고
    • Estrogen and cognition: Applying preclinical findings to clinical perspectives
    • DOI 10.1002/jnr.10811
    • Gibbs R. B, R. Gabor: Estrogen and cognition: applying preclinical findings to clinical perspectives. J Neurosci Res 74, 637-643 (2003) (Pubitemid 37475444)
    • (2003) Journal of Neuroscience Research , vol.74 , Issue.5 , pp. 637-643
    • Gibbs, R.B.1    Gabor, R.2
  • 133
    • 0037067316 scopus 로고    scopus 로고
    • 17β-Estradiol stimulates regeneration of sciatic nerve in female mice
    • DOI 10.1016/S0006-8993(02)02827-5, PII S0006899302028275
    • Islamov R. R, W. A. Hendricks, R. J. Jones, G. J. Lyall, N. S. Spanier, A. K. Murashov: 17Beta-estradiol stimulates regeneration of sciatic nerve in female mice. Brain Res 943, 283-286. (2002) (Pubitemid 36120387)
    • (2002) Brain Research , vol.943 , Issue.2 , pp. 283-286
    • Islamov, R.R.1    Hendricks, W.A.2    Jones, R.J.3    Lyall, G.J.4    Spanier, N.S.5    Murashov, A.K.6
  • 134
    • 0037095722 scopus 로고    scopus 로고
    • Low levels of estrogen significantly diminish axonal sprouting after entorhinal cortex lesions in the mouse
    • Kadish I, T. J. Van Groen: Low levels of estrogen significantly diminish axonal sprouting after entorhinal cortex lesions in the mouse. Neurosci 22, 4095-4102 (2002) (Pubitemid 37465717)
    • (2002) Journal of Neuroscience , vol.22 , Issue.10 , pp. 4095-4102
    • Kadish, I.1    Van Groen, T.2
  • 135
    • 0022889370 scopus 로고
    • Gonadal steroids influence axon sprouting in the hippocampal dentate gyrus: A sexually dimorphic response
    • DOI 10.1016/0014-4886(86)90244-X
    • Morse J. K, S. W. Scheff, S. T. DeKosky: Gonadal steroids influence axon sprouting in the hippocampal dentate gyrus: a sexually dimorphic response. Exp Neurol 94, 649-658 (1986) (Pubitemid 17223467)
    • (1986) Experimental Neurology , vol.94 , Issue.3 , pp. 649-658
    • Morse, J.K.1    Scheff, S.W.2    DeKosky, S.T.3
  • 136
    • 11144328239 scopus 로고    scopus 로고
    • Ovarian steroids influence cell proliferation in the dentate gyrus of the adult female rat in a dose- and time-dependent manner
    • DOI 10.1002/cne.20385
    • Tanapat P, N. B. Hastings, E. Gould: Ovarian steroids influence cell proliferation in the dentate gyrus of the adult female rat in a dose-and time-dependent manner. J Comp Neurol 481, 252-265 (2005) (Pubitemid 40023535)
    • (2005) Journal of Comparative Neurology , vol.481 , Issue.3 , pp. 252-265
    • Tanapat, P.1    Hastings, N.B.2    Gould, E.3
  • 137
    • 0034667294 scopus 로고    scopus 로고
    • Regulation of hippocampal neurogenesis in adulthood
    • Gould E, P. Tanapat, T. Rydel, N. Hastings: Regulation of hippocampal neurogenesis in adulthood. Biol Psychiatry 48, 715-20 (2000)
    • (2000) Biol Psychiatry , vol.48 , pp. 715-720
    • Gould, E.1    Tanapat, P.2    Rydel, T.3    Hastings, N.4
  • 138
    • 33645098296 scopus 로고    scopus 로고
    • Is there a link between adult neurogenesis and learning?
    • Leuner B, E. Gould, T. J. Shors: Is there a link between adult neurogenesis and learning? Hippocampus 16, 216-224 (2006)
    • (2006) Hippocampus , vol.16 , pp. 216-224
    • Leuner, B.1    Gould, E.2    Shors, T.J.3
  • 139
    • 0023922968 scopus 로고
    • Estrogen and insulin synergism in neurite growth enhancement in vitro: Mediation of steroid effects by interactions with growth factors?
    • Toran-Allerand C. D, L. Ellis, K. H. Pfenninger: Estrogen and insulin synergism in neurite growth enhancement in vitro: mediation of steroid effects by interactions with growth factors? Brain Res 469, 87-100 (1988)
    • (1988) Brain Res , vol.469 , pp. 87-100
    • Toran-Allerand, C.D.1    Ellis, L.2    Pfenninger, K.H.3
  • 140
    • 0026047799 scopus 로고
    • Estrogen-enhanced neurite growth: Evidence for a selective induction of Tau and stable microtubules
    • Ferreira A, A. Caceres: Estrogen-enhanced neurite growth: evidence for a selective induction of Tau and stable microtubules. J Neurosci 11, 392-400 (1991)
    • (1991) J Neurosci , vol.11 , pp. 392-400
    • Ferreira, A.1    Caceres, A.2
  • 141
    • 0026714746 scopus 로고
    • Time lapse study of neurite growth in hypothalamic dissociated neurons in culture: Sex differences and estrogen
    • Diaz H. A. Lorenzo, H. F.Carrer, A. Caceres: Time lapse study of neurite growth in hypothalamic dissociated neurons in culture: sex differences and estrogen. J Neurosci. Res 33, 266-281 (1992)
    • (1992) J Neurosci. Res , vol.33 , pp. 266-281
    • Diaz, H.1    Lorenzo, A.2    Carrer, F.H.3    Caceres, A.4
  • 142
    • 0030780109 scopus 로고    scopus 로고
    • 17 β-estradiol enhances the outgrowth and survival of neocortical neurons in culture
    • DOI 10.1023/A:1022015005508
    • Brinton R. D, J. Tran, P. Proffitt, M. Montoya. 17 beta-Estradiol enhances the outgrowth and survival of neocortical neurons in culture. Neurochem Res 22, 1339-1351 (1997) (Pubitemid 27461133)
    • (1997) Neurochemical Research , vol.22 , Issue.11 , pp. 1339-1351
    • Brinton, R.D.1    Tran, J.2    Proffitt, P.3    Montoya, M.4
  • 143
    • 0028844138 scopus 로고
    • Neurodegeneration in the central nervous system of apoE-deficient mice
    • Masliah E, M. Mallory, N. Ge, M. Alford, I. Veinbergs, A. D. Roses: Neurodegeneration in the central nervous system of apoE-deficient mice. Exp Neurol 136, 107-122. 1995)
    • (1995) Exp Neurol , vol.136 , pp. 107-122
    • Masliah, E.1    Mallory, M.2    Ge, N.3    Alford, M.4    Veinbergs, I.5    Roses, A.D.6
  • 146
    • 0034814057 scopus 로고    scopus 로고
    • Interleukin-1 promotion of MAPK-p38 overexpression in experimental animals and in Alzheimer's disease: Potential significance for tau protein phosphorylation
    • DOI 10.1016/S0197-0186(01)00041-9, PII S0197018601000419
    • Sheng J. G, R. A. Jones, X. Q. Zhou, J. M. McGinness, L. J. Van Eldik, R. E. Mrak, W. S. Griffin: Interleukin-1 promotion of MAPK-p38 overexpression in experimental animals and in Alzheimer's disease: potential significance for tau protein phosphorylation. Neurochem Int 39, 341-348 (2001) (Pubitemid 32907398)
    • (2001) Neurochemistry International , vol.39 , Issue.5-6 , pp. 341-348
    • Sheng, J.G.1    Jones, R.A.2    Zhou, X.Q.3    McGinness, J.M.4    Van Eldik, L.J.5    Mrak, R.E.6    Griffin, W.S.T.7
  • 148
    • 2642585855 scopus 로고    scopus 로고
    • Augmented delayed infarct expansion and reactive astrocytosis after permanent focal ischemia in apolipoprotein E4 knock-in mice
    • Mori T, T. Town, M. Kobayashi, J. Tan, S. C. Fujita, T. Asano: Augmented delayed infarct expansion and reactive astrocytosis after permanent focal ischemia in apolipoprotein E4 knock-in mice. J Cereb Blood Flow Metab 24, 646-656 (2004) (Pubitemid 38725369)
    • (2004) Journal of Cerebral Blood Flow and Metabolism , vol.24 , Issue.6 , pp. 646-656
    • Mori, T.1    Town, T.2    Kobayashi, M.3    Tan, J.4    Fujita, S.C.5    Asano, T.6
  • 149
    • 0032101868 scopus 로고    scopus 로고
    • Evidence for normal aging of the septo-hippocampal cholinergic system in apoE (-/-) mice but impaired clearance of axonal degeneration products following injury
    • DOI 10.1006/exnr.1998.6818
    • Fagan A. M, B. A. Murphy, S. N. Patel, J. F. Kilbridge, W. C., Mobley, G Bu, D. M. Holtzman:. Evidence for normal aging of the septo-hippocampal cholinergic system in apoE (-/-) mice but impaired clearance of axonal degeneration products following injury. Exp Neurol 151, 314-325 (1998) (Pubitemid 28285911)
    • (1998) Experimental Neurology , vol.151 , Issue.2 , pp. 314-325
    • Fagan, A.M.1    Murphy, B.A.2    Patel, S.N.3    Kilbridge, J.F.4    Mobley, W.C.5    Bu, G.6    Holtzman, D.M.7
  • 150
    • 0034779324 scopus 로고    scopus 로고
    • Delayed, but marked, expression of apolipoprotein E is involved in tissue clearance after cerebral infarction
    • Kitagawa K, M. Matsumoto, K. Kuwabara, T. Ohtsuki, M. Hori: Delayed, but marked, expression of apolipoprotein E is involved in tissue clearance after cerebral infarction. J Cereb Blood Flow Metab 21, 1199-1207 (2001) (Pubitemid 32947486)
    • (2001) Journal of Cerebral Blood Flow and Metabolism , vol.21 , Issue.10 , pp. 1199-1207
    • Kitagawa, K.1    Matsumoto, M.2    Kuwabara, K.3    Ohtsuki, T.4    Hori, M.5
  • 151
    • 0001665337 scopus 로고
    • Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor
    • Herz J, U. Hamann, S. Rogne, O. Myklebost, H. Gausepohl, K. K. Stanley: Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor. EMBO J. 7, 4119-4127 (1988)
    • (1988) EMBO J. , vol.7 , pp. 4119-4127
    • Herz, J.1    Hamann, U.2    Rogne, S.3    Myklebost, O.4    Gausepohl, H.5    Stanley, K.K.6
  • 152
    • 0025302165 scopus 로고
    • Opposing effects of apolipoproteins e and C on lipoprotein binding to low density lipoprotein receptor-related protein
    • Kowal R. C, J. Herz, K. H. Weisgraber, R. W. Mahley, M. S. Brown, J. L. Goldstein: Opposing effects of apolipoproteins E and C on lipoprotein binding to low density lipoprotein receptor-related protein. J Biol Chem 265, 10771-10779 (1990)
    • (1990) J Biol Chem , vol.265 , pp. 10771-10779
    • Kowal, R.C.1    Herz, J.2    Weisgraber, K.H.3    Mahley, R.W.4    Brown, M.S.5    Goldstein, J.L.6
  • 153
    • 0026778830 scopus 로고
    • Rabbit very low density lipoprotein receptor: A low density lipoprotein receptor-like protein with distinct ligand specificity
    • Takahashi S. Y. Kawarabayasi, T. Nakai, J. Sakai, T. Yamamoto: Rabbit very low density lipoprotein receptor: a low density lipoprotein receptor-like protein with distinct ligand specificity. Proc Natl Acad Sci USA 89, 9252-9256 (1992)
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9252-9256
    • Takahashi, S.1    Kawarabayasi, Y.2    Nakai, T.3    Sakai, J.4    Yamamoto, T.5
  • 154
    • 0027079937 scopus 로고
    • Low density lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance
    • Willnow T. E , J. L. Goldstein, K. Orth, M. S. Brown, J. Herz: Low density lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance J Biol Chem 267, 26172-26180 (1992) (Pubitemid 23014032)
    • (1992) Journal of Biological Chemistry , vol.267 , Issue.36 , pp. 26172-26180
    • Willnow, T.E.1    Goldstein, J.L.2    Orth, K.3    Brown, M.S.4    Herz, J.5
  • 155
    • 0029097983 scopus 로고
    • Fatty acids from degenerating myelin lipids are conserved and reutilized for myelin synthesis during regeneration in peripheral nerve
    • Goodrum J. F, J. E. Weaver, N. D. Goines, T. W. Bouldin: Fatty acids from degenerating myelin lipids are conserved and reutilized for myelin synthesis during regeneration in peripheral nerve. J Neurochem 65, 1752-1759 (1995)
    • (1995) J Neurochem , vol.65 , pp. 1752-1759
    • Goodrum, J.F.1    Weaver, J.E.2    Goines, N.D.3    Bouldin, T.W.4
  • 156
    • 0027298061 scopus 로고
    • Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats
    • DOI 10.1016/0306-4522(93)90456-P
    • Poirier J, A. Baccichet, D. Dea, S. Gauthier: Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats. Neuroscience 55, 81-90 (1993) (Pubitemid 23194987)
    • (1993) Neuroscience , vol.55 , Issue.1 , pp. 81-90
    • Poirier, J.1    Baccichet, A.2    Dea, D.3    Gauthier, S.4
  • 159
    • 0025826774 scopus 로고
    • Astrocytic apolipoprotein e mRNA and GFAP mRNA in hippocampus after entorhinal cortex lesioning
    • Poirier J, M. Hess, P. C. May, C. E. Finch: Astrocytic apolipoprotein E mRNA and GFAP mRNA in hippocampus after entorhinal cortex lesioning. Brain Res Mol Brain Res 11, 97-106 (1991)
    • (1991) Brain Res Mol Brain Res , vol.11 , pp. 97-106
    • Poirier, J.1    Hess, M.2    May, P.C.3    Finch, C.E.4
  • 160
    • 0035211657 scopus 로고    scopus 로고
    • Apolipoprotein E is upregulated in olfactory bulb glia following peripheral receptor lesion in mice
    • DOI 10.1006/exnr.2001.7762
    • Nathan B. P, R. Nisar, S. Randall, J. Short, M. Sherrow, G. K. Wong, R. G. Struble: Apolipoprotein E is upregulated in olfactory bulb glia following peripheral receptor lesion in mice. Exp Neurol 172, 128-136 (2001) (Pubitemid 33141160)
    • (2001) Experimental Neurology , vol.172 , Issue.1 , pp. 128-136
    • Nathan, B.P.1    Nisar, R.2    Randall, S.3    Short, J.4    Sherrow, M.5    Wong, G.K.6    Struble, R.G.7
  • 161
    • 0034055035 scopus 로고    scopus 로고
    • Dominant negative effects of apolipoprotein E4 revealed in transgenic models of neurodegenerative disease
    • DOI 10.1016/S0306-4522(00)00069-5, PII S0306452200000695
    • Buttini M, H. Akeefe, C. Lin, R. W. Mahley, R. E. Pitas, T. Wyss-Coray, L. Mucke: Dominant negative effects of apolipoprotein E4 revealed in transgenic models of neurodegenerative disease. Neuroscience 97, 207-210 (2000) (Pubitemid 30224757)
    • (2000) Neuroscience , vol.97 , Issue.2 , pp. 207-210
    • Buttini, M.1    Akeefe, H.2    Lin, C.3    Mahley, R.W.4    Pitas, R.E.5    Wyss-Coray, T.6    Mucke, L.7
  • 162
    • 33244459117 scopus 로고    scopus 로고
    • A deficit in astroglial organization causes the impaired reactive sprouting in human apolipoprotein E4 targeted replacement mice
    • DOI 10.1016/j.nbd.2005.08.010, PII S096999610500238X
    • Blain J. F, P. M. Sullivan, J. Poirier: A deficit in astroglial organization causes the impaired reactive sprouting in human apolipoprotein E4 targeted replacement mice. Neurobiol Dis 21, 505-514 (2006) (Pubitemid 43277533)
    • (2006) Neurobiology of Disease , vol.21 , Issue.3 , pp. 505-514
    • Blain, J.-F.1    Sullivan, P.M.2    Poirier, J.3
  • 163
    • 0030872230 scopus 로고    scopus 로고
    • Altered synaptic plasticity in hippocampal CA1 area of apolipoprotein E deficient mice
    • Krugers H. J, M. Mulder, J. Korf, L. Havekes, E. R. de Kloet, M. Joels: Altered synaptic plasticity in hippocampal CA1 area of apolipoprotein E deficient mice. Neuroreport 8, 2505-2510 (1997) (Pubitemid 27308451)
    • (1997) NeuroReport , vol.8 , Issue.11 , pp. 2505-2510
    • Krugers, H.J.1    Mulder, M.2    Korf, J.3    Havekes, L.4    De Kloet, E.R.5    Joels, M.6
  • 164
  • 166
    • 0025946899 scopus 로고
    • Spreading depression increases immunohistochemical staining of glial fibrillary acidic protein
    • Kraig R. P, L. M. Dong, R. Thisted, C. B. Jaeger: Spreading depression increases immunohistochemical staining of glial fibrillary acidic protein. J Neurosci 11, 2187-2198 (1991)
    • (1991) J Neurosci , vol.11 , pp. 2187-2198
    • Kraig, R.P.1    Dong, L.M.2    Thisted, R.3    Jaeger, C.B.4
  • 167
    • 0033612341 scopus 로고    scopus 로고
    • Apolipoprotein E immunoreactivity in human and mouse olfactory bulb
    • DOI 10.1016/S0304-3940(99)00352-3, PII S0304394099003523
    • Struble R. G, J. Short, M. Ghobrial, B. P. Nathan: Apolipoprotein E immunoreactivity in human and mouse olfactory bulb. Neurosci Lett. 267, 137-140 (1999) (Pubitemid 29251605)
    • (1999) Neuroscience Letters , vol.267 , Issue.2 , pp. 137-140
    • Struble, R.G.1    Short, J.2    Ghobrial, M.3    Nathan, B.P.4
  • 168
    • 33846929940 scopus 로고    scopus 로고
    • The distribution of apolipoprotein E in mouse olfactory epithelium
    • DOI 10.1016/j.brainres.2006.12.036, PII S000689930603592X
    • Nathan B. P, S. Nannapaneni, S. Gairhe, I. Nwosu, R. G. Struble: The distribution of apolipoprotein E in mouse olfactory epithelium. Brain Res 1137, 78-83 (2007) (Pubitemid 46240053)
    • (2007) Brain Research , vol.1137 , Issue.1 , pp. 78-83
    • Nathan, B.P.1    Nannapaneni, S.2    Gairhe, S.3    Nwosu, I.4    Struble, R.G.5
  • 170
    • 0028232662 scopus 로고
    • Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro
    • Nathan B. P, S. Bellosta, D. A. Sanan, K. H. Weisgraber, R. W. Mahley, R. E. Pitas: Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro. Science 264, 850-852 (1994) (Pubitemid 24193454)
    • (1994) Science , vol.264 , Issue.5160 , pp. 850-852
    • Nathan, B.P.1    Bellosta, S.2    Sanan, D.A.3    Weisgraber, K.H.4    Mahley, R.W.5    Pitas, R.E.6
  • 171
    • 0029157112 scopus 로고
    • The inhibitory effect of apolipoprotein E4 on neurite outgrowth is associated with microtubule depolymerization
    • Nathan B. P, K. C. Chang, S. Bellosta, E. Brisch, N. Ge, R. W. Mahley, R. E. Pitas: The inhibitory effect of apolipoprotein E4 on neurite outgrowth is associated with microtubule depolymerization. J Biol Chem 270, 19791-19799 (1995)
    • (1995) J Biol Chem , vol.270 , pp. 19791-19799
    • Nathan, B.P.1    Chang, K.C.2    Bellosta, S.3    Brisch, E.4    Ge, N.5    Mahley, R.W.6    Pitas, R.E.7
  • 172
    • 0032708306 scopus 로고    scopus 로고
    • Apolipoprotein e isoform-specific differences in neuronal sprouting in organotypic hippocampal culture
    • Teter B, P. T. Xu, J. R. Gilbert, A. D. Roses, D. Galasko, G. M. Cole: Apolipoprotein E isoform-specific differences in neuronal sprouting in organotypic hippocampal culture. J Neurochem 73, 2613-2616 (1999)
    • (1999) J Neurochem , vol.73 , pp. 2613-2616
    • Teter, B.1    Xu, P.T.2    Gilbert, J.R.3    Roses, A.D.4    Galasko, D.5    Cole, G.M.6
  • 173
    • 1842790914 scopus 로고    scopus 로고
    • Glial lipoproteins stimulate axon growth of central nervous system neurons in compartmented cultures
    • DOI 10.1074/jbc.M313828200
    • Hayashi H, R. B. Campenot, D. E. Vance, J. E. Vance: Glial lipoproteins stimulate axon growth of central nervous system neurons in compartmented cultures. J Biol Chem 279, 14009-14015 (2004) (Pubitemid 38468935)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.14 , pp. 14009-14015
    • Hayashi, H.1    Campenot, R.B.2    Vance, D.E.3    Vance, J.E.4
  • 174
    • 0037154858 scopus 로고    scopus 로고
    • Apolipoprotein E4 inhibits, and apolipoprotein E3 promotes neurite outgrowth in cultured adult mouse cortical neurons through the low-density lipoprotein receptor-related protein
    • DOI 10.1016/S0006-8993(01)03367-4, PII S0006899301033674
    • Nathan B. P, Y. Jiang, G. K. Wong, F. Shen, G. J. Brewer, R. G. Struble: Apolipoprotein E4 inhibits, and apolipoprotein E3 promotes neurite outgrowth in cultured adult mouse cortical neurons through the low-density lipoprotein receptor-related protein. Brain Res 928, 96-105 (2002) (Pubitemid 34159056)
    • (2002) Brain Research , vol.928 , Issue.1-2 , pp. 96-105
    • Nathan, B.P.1    Jiang, Y.2    Wong, G.K.3    Shen, F.4    Brewer, G.J.5    Struble, R.G.6
  • 175
    • 3042647308 scopus 로고    scopus 로고
    • Estrogen facilitates neurite extension via apolipoprotein E in cultured adult mouse cortical neurons
    • DOI 10.1210/en.2003-1707
    • Nathan B. P, A. G. Barsukova, F. Shen, M. McAsey, R. G. Struble: Estrogen facilitates neurite extension via apolipoprotein E in cultured adult mouse cortical neurons. Endocrinology 145, 3065-3073, (2004) (Pubitemid 38829971)
    • (2004) Endocrinology , vol.145 , Issue.7 , pp. 3065-3073
    • Nathan, B.P.1    Barsukova, A.G.2    Shen, F.3    McAsey, M.4    Struble, R.G.5
  • 176
    • 0023642584 scopus 로고
    • Production of superoxide anions by a CNS macrophage, the microglia
    • Colton C. A, D. L. Gilbert: Production of superoxide anions by a CNS macrophage, the microglia. FEBS Lett 223, 284-288 (1987)
    • (1987) FEBS Lett , vol.223 , pp. 284-288
    • Colton, C.A.1    Gilbert, D.L.2
  • 177
    • 0030610645 scopus 로고    scopus 로고
    • Microglial activation by alzhelmer amyloid precursor protein and modulation by apolipoprotein E
    • DOI 10.1038/42257
    • Barger S. W, A. D. Harmon: Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E. Nature 388, 878-881 (1997) (Pubitemid 27377060)
    • (1997) Nature , vol.388 , Issue.6645 , pp. 878-881
    • Barger, S.W.1    Harmon, A.D.2
  • 181
    • 0036135127 scopus 로고    scopus 로고
    • Apolipoprotein E affects the central nervous system response to injury and the development of cerebral edema
    • DOI 10.1002/ana.10098
    • Lynch J. R, J. A. Pineda, D. Morgan, L. Zhang, D. S. Warner, H Benveniste, D. T. Laskowitz: Apolipoprotein E affects the central nervous system response to injury and the development of cerebral edema. Ann Neurol 51, 113-117 (2002) (Pubitemid 34027983)
    • (2002) Annals of Neurology , vol.51 , Issue.1 , pp. 113-117
    • Lynch, J.R.1    Pineda, J.A.2    Morgan, D.3    Zhang, L.4    Warner, D.S.5    Benveniste, H.6    Laskowitz, D.T.7
  • 183
    • 0035283401 scopus 로고    scopus 로고
    • Apolipoprotein E modulates glial activation and the endogenous central nervous system inflammatory response
    • DOI 10.1016/S0165-5728(00)00459-8, PII S0165572800004598
    • Lynch J. R, D. Morgan, J. Mance, W. D. Matthew, D. T. Laskowitz: Apolipoprotein E modulates glial activation and the endogenous central nervous system inflammatory response. J Neuroimmunol 114, 107-113 (2001) (Pubitemid 32184731)
    • (2001) Journal of Neuroimmunology , vol.114 , Issue.1-2 , pp. 107-113
    • Lynch, J.R.1    Morgan, D.2    Mance, J.3    Matthew, W.D.4    Laskowitz, D.T.5
  • 186
    • 0037219011 scopus 로고    scopus 로고
    • Microglial function in human APOE3 and APOE4 transgenic mice: Altered arginine transport
    • DOI 10.1016/S0165-5728(02)00394-6, PII S0165572802003946
    • Czapiga M, C. A. Colton: Microglial function in human APOE3 and APOE4 transgenic mice: altered arginine transport. J Neuroimmunol 134, 44-51 (2003) (Pubitemid 36050829)
    • (2003) Journal of Neuroimmunology , vol.134 , Issue.1-2 , pp. 44-51
    • Czapiga, M.1    Colton, C.A.2
  • 188
    • 11444251209 scopus 로고    scopus 로고
    • Sex steroids, APOE genotype and the innate immune system
    • DOI 10.1016/j.neurobiolaging.2004.08.001, PII S0197458004002659, Developmental Origins of Aging in the Brain and Blood Vessels
    • Colton C. A, C. M. Brown, M. P. Vitek: Sex steroids, APOE genotype and the innate immune system. Neurobiol Aging 26, 363-372. (2005) (Pubitemid 40082720)
    • (2005) Neurobiology of Aging , vol.26 , Issue.3 , pp. 363-372
    • Colton, C.A.1    Brown, C.M.2    Vitek, M.P.3
  • 191
    • 0348141712 scopus 로고    scopus 로고
    • Chemokines promote quiescence and survival of human neural progenitor cells
    • Krathwohl M. D, J. L. Kaiser. Chemokines promote quiescence and survival of human neural progenitor cells. Stem Cells 22, 109-118. (2004) (Pubitemid 38018787)
    • (2004) Stem Cells , vol.22 , Issue.1 , pp. 109-118
    • Krathwohl, M.D.1    Kaiser, J.L.2
  • 193
    • 33846170909 scopus 로고    scopus 로고
    • Environmental enrichment stimulates neurogenesis in apolipoprotein E3 and neuronal apoptosis in apolipoprotein E4 transgenic mice
    • DOI 10.1111/j.1471-4159.2006.04189.x
    • Levi O, D. M. Michaelson: Environmental enrichment stimulates neurogenesis in apolipoprotein E3 and neuronal apoptosis in apolipoprotein E4 transgenic mice. J Neurochem 100, 202-210 (2007) (Pubitemid 46085849)
    • (2007) Journal of Neurochemistry , vol.100 , Issue.1 , pp. 202-210
    • Levi, O.1    Michaelson, D.M.2
  • 194
    • 0042337371 scopus 로고    scopus 로고
    • Divergent impact of progesterone and medroxyprogesterone acetate (Provera) on nuclear mitogen-activated protein kinase signaling
    • DOI 10.1073/pnas.1334098100
    • Nilsen J, R. D. Brinton: Divergent impact of progesterone and medroxyprogesterone acetate (Provera) on nuclear mitogen-activated protein kinase signaling. Proc Natl Acad Sci U S A 100, 10506-10511 (2003) (Pubitemid 37071908)
    • (2003) Proceedings of the National Academy of Sciences of the United States of America , vol.100 , Issue.18 , pp. 10506-10511
    • Nilsen, J.1    Brinton, R.D.2
  • 195
    • 33750952697 scopus 로고    scopus 로고
    • Activation of estrogen receptor α increases and estrogen receptor β decreases apolipoprotein E expression in hippocampus in vitro and in vivo
    • DOI 10.1073/pnas.0608128103
    • Wang J. M, R. W. Irwin, R. D. Brinton: Activation of estrogen receptor alpha increases and estrogen receptor beta decreases apolipoprotein E expression in hippocampus in vitro and in vivo. Proc Natl Acad Sci U S A 103, 16983-16988 (2006) (Pubitemid 44737364)
    • (2006) Proceedings of the National Academy of Sciences of the United States of America , vol.103 , Issue.45 , pp. 16983-16988
    • Wang, J.M.1    Irwin, R.W.2    Brinton, R.D.3
  • 196
    • 0031079601 scopus 로고    scopus 로고
    • Astrocytes and microglia respond to estrogen with increased apoE mRNA in vivo and in vitro
    • DOI 10.1006/exnr.1996.6360
    • Stone D. J, I. Rozovsky, T. E. Morgan, C. P. Anderson, H. Hajian, C. E. Finch: Astrocytes and microglia respond to estrogen with increased apoE mRNA in vivo and in vitro. Exp Neurol 143, 313-318 (1997) (Pubitemid 27148235)
    • (1997) Experimental Neurology , vol.143 , Issue.2 , pp. 313-318
    • Stone, D.J.1    Rozovsky, I.2    Morgan, T.E.3    Anderson, C.P.4    Hajian, H.5    Finch, C.E.6
  • 197
    • 0027520373 scopus 로고
    • Gonadal hormones down-regulate reactive gliosis and astrocyte proliferation after a penetrating brain injury
    • DOI 10.1016/0006-8993(93)90964-O
    • Garcia-Estrada J, J. A. Del Rio, S. Luquin, E. Soriano, L. M. Garcia-Segura: Gonadal hormones downregulate reactive gliosis and astrocyte proliferation after a penetrating brain injury. Brain Res 628, 271-278 (1993) (Pubitemid 23331618)
    • (1993) Brain Research , vol.628 , Issue.1-2 , pp. 271-278
    • Garcia-Estrada, J.1    Del Rio, J.A.2    Luquin, S.3    Soriano, E.4    Garcia-Segura, L.M.5
  • 198
    • 33750929762 scopus 로고    scopus 로고
    • Neocortical and hippocampal glial fibrillary acidic protein immunoreactivity shows region-specific variation during the mouse estrous cycle
    • DOI 10.1159/000095340
    • Struble R. G, S. Afridi, S. Beckman-Randall, M. Li, C. Cady, B. Nathan, M. E. McAsey: Neocortical and hippocampal glial fibrillary acidic protein immunoreactivity shows region-specific variation during the mouse estrous cycle. Neuroendocrinology 83, 325-335 (2006) (Pubitemid 44729790)
    • (2006) Neuroendocrinology , vol.83 , Issue.5-6 , pp. 325-335
    • Struble, R.G.1    Afridi, S.2    Beckman-Randall, S.3    Li, M.4    Cady, C.5    Nathan, B.6    McAsey, M.E.7
  • 199
    • 0030727813 scopus 로고    scopus 로고
    • Comparative distribution of estrogen receptor-α and -β mRNA in the rat central nervous system
    • DOI 10.1002/(SICI)1096-9861(19971201)388:4<507::AID-CNE1>3.0.CO;2-6
    • Shughrue P. J, M. V. Lane, I. Merchenthaler: Comparative distribution of estrogen receptor-alpha and-beta mRNA in the rat central nervous system. J Comp Neurol 388, 507-25 (1997) (Pubitemid 27481288)
    • (1997) Journal of Comparative Neurology , vol.388 , Issue.4 , pp. 507-525
    • Shughrue, P.J.1    Lane, M.V.2    Merchenthaler, I.3
  • 200
    • 0034706068 scopus 로고    scopus 로고
    • Evidence for novel estrogen binding sites in the rat hippocampus
    • Shughrue P. J, I. Merchenthaler: Evidence for novel estrogen binding sites in the rat hippocampus. Neuroscience 99, 605-612. 2000)
    • (2000) Neuroscience , vol.99 , pp. 605-612
    • Shughrue, P.J.1    Merchenthaler, I.2
  • 201
    • 0023080585 scopus 로고
    • Astrocytes synthesize apolipoprotein e and metabolize apolipoprotein E-containing lipoproteins
    • Pitas R. E, J. K. Boyles, S. H. Lee, D. Foss, R. W. Mahley: Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins. Biochim Biophys Acta 917, 48-61 (1987)
    • (1987) Biochim Biophys Acta , vol.917 , pp. 48-61
    • Pitas, R.E.1    Boyles, J.K.2    Lee, S.H.3    Foss, D.4    Mahley, R.W.5
  • 202
    • 0022350033 scopus 로고
    • Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system
    • Boyles J. K, R. E .Pitas, E. Wilson, R. W. Mahley, J. M. Taylor: Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system. J Clin. Invest 76, 1501-1513 (1985) (Pubitemid 16193568)
    • (1985) Journal of Clinical Investigation , vol.76 , Issue.4 , pp. 1501-1513
    • Boyles, J.K.1    Pitas, R.E.2    Wilson, E.3
  • 203
    • 0031731092 scopus 로고    scopus 로고
    • Bidirectional transcription regulation of glial fibrillary acidic protein by estradiol in vivo and in vitro
    • DOI 10.1210/en.139.7.3202
    • Stone D. J, Y. Song, C. P. Anderson, K. K. Krohn, C. E. Finch, I. Rozovsky: Bidirectional transcription regulation of glial fibrillary acidic protein by estradiol in vivo and in vitro. Endocrinology 139, 3202-3209 (1998) (Pubitemid 28512350)
    • (1998) Endocrinology , vol.139 , Issue.7 , pp. 3202-3209
    • Stone, D.J.1    Song, Y.2    Anderson, C.P.3    Krohn, K.K.4    Finch, C.E.5    Rozovsky, I.6
  • 204
    • 0035047691 scopus 로고    scopus 로고
    • Dynamic signaling between astrocytes and neurons
    • DOI 10.1146/annurev.physiol.63.1.795
    • Araque A, G. Carmignoto, P. G. Haydon. Dynamic signaling between astrocytes and neurons. Ann Rev Physiol 63, 795-813 (2001) (Pubitemid 32304337)
    • (2001) Annual Review of Physiology , vol.63 , pp. 795-813
    • Araque, A.1    Carmignoto, G.2    Haydon, P.G.3
  • 205
    • 1442274664 scopus 로고    scopus 로고
    • Role of glia in neuroendocrine function
    • Garcia-Segura L. M, M. M. McCarthy. Role of glia in neuroendocrine function. Endocrinology 145, 1082-1086 (2004)
    • (2004) Endocrinology , vol.145 , pp. 1082-1086
    • Garcia-Segura, L.M.1    McCarthy, M.M.2
  • 206
    • 33845581250 scopus 로고    scopus 로고
    • Estradiol regulation of astroglia and apolipoprotein E: An important role in neuronal regeneration
    • DOI 10.1016/j.exger.2006.05.013, PII S0531556506001720
    • Struble R. G, B. P. Nathan, C. Cady, X. Cheng, M. McAsey: Estradiol regulation of astroglia and apolipoprotein E: An important role in neuronal regeneration. Exp Gerontol 42, 54-63 (2007) (Pubitemid 44937823)
    • (2007) Experimental Gerontology , vol.42 , Issue.1-2 , pp. 54-63
    • Struble, R.G.1    Nathan, B.P.2    Cady, C.3    Cheng, X.4    McAsey, M.5
  • 207
    • 0032929864 scopus 로고    scopus 로고
    • An increase in lactate output by brain tissue serves to meet the energy needs of glutamate-activated neurons
    • Schurr A, J. J. Miller, R. S. Payne, B. M. Rigor: An increase in lactate output by brain tissue serves to meet the energy needs of glutamate-activated neurons. J Neurosci 19, 34-39 (1999) (Pubitemid 29028946)
    • (1999) Journal of Neuroscience , vol.19 , Issue.1 , pp. 34-39
    • Schurr, A.1    Miller, J.J.2    Payne, R.S.3    Rigor, B.M.4
  • 208
    • 3042793425 scopus 로고    scopus 로고
    • Neural activity triggers neuronal oxidative metabolism followed by astrocytic glycolysis
    • DOI 10.1126/science.1096485
    • Kasischke K. A, H. D. Vishwasrao, P. J. Fisher, W. R. Zipfel, W. W. Webb: Neural activity triggers neuronal oxidative metabolism followed by astrocytic glycolysis. Science 305, 99-103 (2004) (Pubitemid 38869381)
    • (2004) Science , vol.305 , Issue.5680 , pp. 99-103
    • Kasischke, K.A.1    Vishwasrao, H.D.2    Fisher, P.J.3    Zipfel, W.R.4    Webb, W.W.5
  • 209
    • 0028143148 scopus 로고
    • The high affinity uptake system for excitatory amino acids in the brain
    • DOI 10.1016/0301-0082(94)90033-7
    • Danbolt N. C: The high affinity uptake system for excitatory amino acids in the brain. Prog Neurobiol 44, 377-396. 1994) (Pubitemid 24337092)
    • (1994) Progress in Neurobiology , vol.44 , Issue.4 , pp. 377-396
    • Danbolt, N.C.1
  • 210
  • 211
    • 0027536702 scopus 로고
    • Neuronalastrocytic interactions in glutamate metabolism
    • Schousboe A, N. Westergaard, L. Hertz: Neuronalastrocytic interactions in glutamate metabolism. Biochem Soc Trans 21, 49-53 (1993)
    • (1993) Biochem Soc Trans , vol.21 , pp. 49-53
    • Schousboe, A.1    Westergaard, N.2    Hertz, L.3
  • 212
    • 0030773837 scopus 로고    scopus 로고
    • Synaptic efficacy enhanced by glial cells in vitro
    • DOI 10.1126/science.277.5332.1684
    • Pfrieger F. W, B. A. Barres: Synaptic efficacy enhanced by glial cells in vitro. Science 277, 1684-1687 (1997) (Pubitemid 27446234)
    • (1997) Science , vol.277 , Issue.5332 , pp. 1684-1687
    • Pfrieger, F.W.1    Barres, B.A.2
  • 213
    • 0035834416 scopus 로고    scopus 로고
    • CNS synaptogenesis promoted by glia-derived cholesterol
    • DOI 10.1126/science.294.5545.1354
    • Mauch D H., K. Nagler, S. Schumacher, C. Goritz, E. C. Muller, A. Otto, F. W. Pfrieger: CNS synaptogenesis promoted by glia-derived cholesterol. Science 294, 1354-1357 (2001) (Pubitemid 33063104)
    • (2001) Science , vol.294 , Issue.5545 , pp. 1354-1357
    • Mauch, D.H.1    Nagier, K.2    Schumacher, S.3    Goritz, C.4    Muller, E.-C.5    Otto, A.6    Pfrieger, F.W.7
  • 214
    • 0035951508 scopus 로고    scopus 로고
    • Control of synapse number by glia
    • DOI 10.1126/science.291.5504.657
    • Ullian E. M, S. K. Sapperstein, . K. S.Christopherson, B. A Barres:. Control of synapse number by glia. Science 291, 657-661 (2001) (Pubitemid 32150425)
    • (2001) Science , vol.291 , Issue.5504 , pp. 657-661
    • Ullian, E.M.1    Sapperstein, S.K.2    Christopherson, K.S.3    Barres, B.A.4
  • 216
    • 0032577419 scopus 로고    scopus 로고
    • Regulation of the phosphorylation of glial fibrillary acidic protein (GFAP) by glutamate and calcium ions in slices of immature rat spinal cord: Comparison with immature hippocampus
    • DOI 10.1016/S0304-3940(98)00340-1, PII S0304394098003401
    • Kommers T, L. Vinade, C. Pereira, C. A. Goncalves, S. Wofchuk, R. Rodnight: Regulation of the phosphorylation of glial fibrillary acidic protein (GFAP) by glutamate and calcium ions in slices of immature rat spinal cord: comparison with immature hippocampus. Neurosci Lett 248, 141-143 (1998) (Pubitemid 28275953)
    • (1998) Neuroscience Letters , vol.248 , Issue.2 , pp. 141-143
    • Kommers, T.1    Vinade, L.2    Pereira, C.3    Goncalves, C.A.4    Wofchuk, S.5    Rodnight, R.6
  • 217
    • 0031149170 scopus 로고    scopus 로고
    • Neuronal regulation of astrocyte morphology in vitro is mediated by GABAergic signaling
    • DOI 10.1002/(SICI)1098-1136(199705)20:1<1::AID-GLIA1>3.0.CO;2-E
    • Matsutani S, N. Yamamoto: Neuronal regulation of astrocyte morphology in vitro is mediated by GABAergic signaling. Glia 20, 1-9 (1997) (Pubitemid 27207003)
    • (1997) GLIA , vol.20 , Issue.1 , pp. 1-9
    • Matsutani, S.1    Yamamoto, N.2
  • 218
    • 0037440418 scopus 로고    scopus 로고
    • Gabaergic signaling mediates the morphological organization of astrocytes in the adult rat forebrain
    • DOI 10.1002/glia.10166
    • Runquist M, G. Alonso: Gabaergic signaling mediates the morphological organization of astrocytes in the adult rat forebrain. Glia 41, 137-151 (2003) (Pubitemid 36262191)
    • (2003) GLIA , vol.41 , Issue.2 , pp. 137-151
    • Runquist, M.1    Alonso, G.2
  • 219
    • 0031030995 scopus 로고    scopus 로고
    • Steroid hormones and excitability in the mammalian brain
    • DOI 10.1006/frne.1996.0144
    • Joels M: Steroid hormones and excitability in the mammalian brain. Front Neuroendocrinol 18, 2-48 (1997) (Pubitemid 27045164)
    • (1997) Frontiers in Neuroendocrinology , vol.18 , Issue.1 , pp. 2-48
    • Joels, M.1
  • 220
    • 0035828176 scopus 로고    scopus 로고
    • The modulatory effect of estrogen on the neuronal activity in the barrel cortex of the rat. An electrophysiological study
    • Kis Z, D. Budai, G. Imre, T. Farkas, S. Horvath, J. Toldi: The modulatory effect of estrogen on the neuronal activity in the barrel cortex of the rat. An electrophysiological study. Neuroreport 12, 2509-2512 (2001) (Pubitemid 32682212)
    • (2001) NeuroReport , vol.12 , Issue.11 , pp. 2509-2512
    • Kis, Z.1    Budai, D.2    Imre, G.3    Farkas, T.4    Horvath, S.5    Toldi, J.6
  • 221
    • 0036376094 scopus 로고    scopus 로고
    • Estrogen actions throughout the brain
    • McEwen B: Estrogen actions throughout the brain. Recent Prog Horm Res 57, 357-384 (2002)
    • (2002) Recent Prog Horm Res , vol.57 , pp. 357-384
    • McEwen, B.1
  • 222
    • 0035449918 scopus 로고    scopus 로고
    • Estrogen regulates functional inhibition of hippocampal CA1 pyramidal cells in the adult female rat
    • Rudick C. N, C. S. Woolley: Estrogen regulates functional inhibition of hippocampal CA1 pyramidal cells in the adult female rat. J Neurosci 21, 6532-6543 (2001) (Pubitemid 32781097)
    • (2001) Journal of Neuroscience , vol.21 , Issue.17 , pp. 6532-6543
    • Rudick, C.N.1    Woolley, C.S.2
  • 223
    • 0038118229 scopus 로고    scopus 로고
    • A role for the basal forebrain cholinergic system in estrogen-induced disinhibition of hippocampal pyramidal cells
    • Rudick C. N, R. B. Gibbs, C. S. Woolley: A role for the basal forebrain cholinergic system in estrogen-induced disinhibition of hippocampal pyramidal cells. J Neurosci 23, 4479-4490 (2003) (Pubitemid 36706178)
    • (2003) Journal of Neuroscience , vol.23 , Issue.11 , pp. 4479-4490
    • Rudick, C.N.1    Gibbs, R.B.2    Woolley, C.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.